Published in Br J Pharmacol on November 01, 1970
Evaluation of mechanisms controlling the release and inactivation of the adrenergic transmitter in the rabbit portal vein and vas deferens. Br J Pharmacol (1972) 4.45
Role of transmitter uptake mechanisms in synaptic neurotransmission. Br J Pharmacol (1971) 3.82
Evidence for the existence of 'atypical' beta-adrenoceptors (beta 3-adrenoceptors) mediating relaxation in the rat distal colon in vitro. Br J Pharmacol (1990) 1.84
Binding of catecholamines to connective tissue and the effect upon the responses of blood vessels to noradrenaline and to nerve stimulation. J Physiol (1973) 1.63
Glucocorticoids have state-dependent stimulant effects on the mesencephalic dopaminergic transmission. Proc Natl Acad Sci U S A (1996) 1.56
The effects of drugs on the sensitivity of the rat anococcygeus muscle to agonists. Br J Pharmacol (1973) 1.53
Evaluation of neuronal and extraneuronal uptake mechanisms during adrenergic nerve stimulation. Br J Pharmacol (1971) 1.34
A basis for migraine therapy- the autonomic theory reappraised. Postgrad Med J (1978) 1.17
Effect of steroids on beta-adrenoceptor-mediated relaxation of pig bronchus. Br J Pharmacol (1983) 1.15
The epidemic of cocaine-related juxtapyloric perforations: with a comment on the importance of testing for Helicobacter pylori. Ann Surg (1999) 1.12
Effects of uptake inhibitors on responses of sheep coronary arteries to catecholamines and sympathetic nerve stimulation. Br J Pharmacol (1979) 1.01
The effects of pargyline on overflow of transmitter and uptake of noradrenaline in the cat spleen. Br J Pharmacol (1973) 1.00
Corticosterone acts in the nucleus accumbens to enhance dopamine signaling and potentiate reinstatement of cocaine seeking. J Neurosci (2013) 0.98
Suppression of glucocorticoid secretion and antipsychotic drugs have similar effects on the mesolimbic dopaminergic transmission. Proc Natl Acad Sci U S A (1996) 0.97
Influence of sex-steroid hormones on the regulation of lymphocyte beta 2-adrenoceptors during the menstrual cycle. Br J Clin Pharmacol (1994) 0.95
Catecholamine uptake by isolated coronary arteries and atria of the kitten. Br J Pharmacol (1978) 0.93
Adaptation during surgical stress. A reevaluation of the role of glucocorticoids. J Clin Invest (1986) 0.93
Involvement of uptake2 in the termination of activity of neurogenic noradrenaline in the rat isolated atrium. J Physiol (1976) 0.92
The accumulation and metabolism of (-)-noradrenaline by cells in culture. Br J Pharmacol (1973) 0.89
The effects of hypercholesterolaemic plasma on vascular sensitivity to noradrenaline. Br J Pharmacol (1975) 0.89
Inhibition of catecholamine uptake in the isolated rat heart by haloalkylamines related to phenoxybenzamine. Br J Pharmacol (1972) 0.86
High-affinity uptake of noradrenaline in postsynaptic neurones. Br J Pharmacol (1993) 0.85
Functional properties of the uptake of amines in immortalised peptidergic neurones (transport-P). Br J Pharmacol (1996) 0.84
Neurobiological mechanisms that contribute to stress-related cocaine use. Neuropharmacology (2013) 0.84
An uptake mechanism for L-noradrenaline in the cat spleen, associated with the nerves but distinct from uptake. J Physiol (1974) 0.83
Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells. Br J Pharmacol (2002) 0.82
Extraneuronal monoamine transporter mediates the permissive action of cortisol in the Guinea pig trachea: possible involvement of tracheal chondrocytes. PLoS One (2013) 0.82
The effect of reserpine treatment on the extraneuronal uptake of [3H]-isoprenaline into rat atria. Br J Pharmacol (1985) 0.82
Studies of uptake of the bretylium analogue, iodobenzyltrimethylammonium iodide, by non-primate, monkey and human hearts. Br J Clin Pharmacol (1979) 0.81
The influence of hormonal and neuronal factors on rat heart adrenoceptors. Br J Pharmacol (1980) 0.81
The influence of amine metabolizing enzymes on the pharmacology of tyramine in the isolated perfused mesenteric arterial bed of the rat. Br J Pharmacol (1989) 0.79
Corticosteroid involvement in the changes in noradrenergic responsiveness of tissues from rats made hypertensive by short-term isolation. Br J Pharmacol (1978) 0.79
The effectiveness of alpha 2-adrenoceptor activation increases from the distal to the proximal part of the veins of canine limbs. Br J Pharmacol (1990) 0.78
On the mechanism of pancuronium-induced supersensitivity to noradrenaline in rat smooth muscle. Br J Pharmacol (1979) 0.78
Basal serum cortisol levels are not predictive of response to corticotropin but have prognostic significance in patients with septic shock. J Korean Med Sci (2007) 0.77
Proceedings: Inhibition of accumulation of adrenaline and noradrenaline in arterial smooth muscle by steroids. Br J Pharmacol (1972) 0.76
Release of endogenous noradrenaline from an isolated elastic artery. J Physiol (1974) 0.75
Modification by betamethasone of the effects of bronchodilator drugs on cholinergic bronchoconstriction in rats. Br J Pharmacol (1984) 0.75
Postsynaptic alpha-adrenoceptor reserve and the shift of the concentration-response curves to the right, as caused by the irreversible alpha-adrenoceptor antagonist phenoxybenzamine. Br J Pharmacol (1987) 0.75
Corticosterone Potentiation of Cocaine-Induced Reinstatement of Conditioned Place Preference in Mice is Mediated by Blockade of the Organic Cation Transporter 3. Neuropsychopharmacology (2016) 0.75
Acidaemia produced by sympathomimetic amines and sympathetic nerve stimulation. J Physiol (1973) 0.75
Effects of ovarian steroids upon responses mediated by adrenoceptors in separated layers of the myometrium and in the costo-uterine muscle of the guinea-pig. Br J Pharmacol (1983) 0.75
Coronary artery spasm. Br Med J (1979) 0.75
The role of uptake2 in the extraneuronal metabolism of catecholamines in the isolated rat heart. Br J Pharmacol (1969) 3.25
Mechanism of hydrocortisone potentiation of responses to epinephrine and norepinephrine in rabbit aorta. Circ Res (1969) 2.53
The influence of the adrenal cortex on behavior of terminal vascular bed. Ann N Y Acad Sci (1953) 2.53
Steroid potentiation of responses to sympathomimetic amines in aortic strips. Br J Pharmacol (1969) 1.90
A UNIFIED THEORY OF GLUCOCORTICOID ACTION. Perspect Biol Med (1964) 1.65
Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J Neurochem (1966) 7.91
The uptake of [3H]GABA by slices of rat cerebral cortex. J Neurochem (1968) 5.05
The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci U S A (1986) 3.97
Role of transmitter uptake mechanisms in synaptic neurotransmission. Br J Pharmacol (1971) 3.82
Effects of 6-hydroxydopamine on catecholamine containing neurones in the rat brain. J Neurochem (1970) 3.42
The role of uptake2 in the extraneuronal metabolism of catecholamines in the isolated rat heart. Br J Pharmacol (1969) 3.25
Opiate analgesics inhibit substance P release from rat trigeminal nucleus. Nature (1977) 2.74
The retrograde axonal transport of nerve growth factor. Brain Res (1974) 2.60
Release of gamma-aminobutyric acid from inhibitory nerves of lobster. Proc Natl Acad Sci U S A (1966) 2.47
Multiple opiate receptor sites on primary afferent fibres. Nature (1980) 2.34
The possible existence of multiple receptors for substance P. Naunyn Schmiedebergs Arch Pharmacol (1982) 2.18
The physiologic disposition and metabolism of norepinephrine in immunosympathectomized animals. J Pharmacol Exp Ther (1966) 2.03
GABA uptake in rat central nervous system: comparison of uptake in slices and homogenates and the effects of some inhibitors. J Neurochem (1971) 2.00
Trans-synaptic regulation of growth and development of adrenergic neurones in a mouse sympathetic ganglion. Brain Res (1971) 1.99
7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proc Natl Acad Sci U S A (1988) 1.99
Release of dopamine from dendrites in rat substantia nigra. Nature (1976) 1.95
Reduced uptake of tritiated noradrenaline in tissues of immunosympathectomized animals. Nature (1965) 1.91
Autoradiographic localization of 3 H-GABA in rat retina. Nat New Biol (1972) 1.90
Effects of phenoxybenzamine on the uptake and metabolism of noradrenaline in the rat heart and vas deferens. Br J Pharmacol (1969) 1.90
Multiple tachykinin binding sites in peripheral tissues and in brain. Eur J Pharmacol (1986) 1.86
Catecholamine uptake processes. Br Med Bull (1973) 1.83
Uptake and metabolism of gamma-aminobutyric acid by neurones and glial cells. Biochem Pharmacol (1975) 1.83
The inhibition of noradrenaline uptake by drugs. Adv Drug Res (1965) 1.82
Use of catechol O-methyltransferase for the enzyme radiochemical assay of dopamine. J Neurochem (1973) 1.82
Capsaicin-induced depletion of substance P from primary sensory neurones. Brain Res (1978) 1.80
Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death. Proc Natl Acad Sci U S A (1994) 1.79
Dopamine receptors in the brain. Science (1975) 1.79
Neurochemical characteristics of early and late onset types of Alzheimer's disease. Br Med J (Clin Res Ed) (1984) 1.78
Uptake mechanisms for neurotransmitter amines. Biochem Pharmacol (1974) 1.73
Tissue selectivity of substance P alkyl esters: suggesting multiple receptors. Eur J Pharmacol (1983) 1.65
Sodium dependence of transmitter uptake at adrenergic nerve terminals. Mol Pharmacol (1966) 1.63
A post-mortem study of the cholinergic and GABA systems in senile dementia. Brain (1982) 1.62
The release of gamma-aminobutyric acid during inhibition in the cat visual cortex. J Physiol (1971) 1.59
Uptake, storage and metabolism of norepinephrine in tissues of the developing rat. J Pharmacol Exp Ther (1967) 1.58
Huntington's chorea. Post-mortem measurement of glutamic acid decarboxylase, choline acetyltransferase and dopamine in basal ganglia. Brain (1974) 1.57
Differences in the regulation of tyrosine hydroxylase and dopa decarboxylase in sympathetic ganglia and adrenals. Nat New Biol (1971) 1.54
Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site. Proc Natl Acad Sci U S A (1990) 1.53
Biochemical and anatomical observations on the degeneration of peptide-containing primary afferent neurons after neonatal capsaicin. Neuroscience (1981) 1.50
A quantitative ultrastructural and biochemical analysis of the process of reinnervation of the superior cervical ganglion in the adult rat. Brain Res (1974) 1.43
Naloxone as a GABA antagonist: evidence from iontophoretic, receptor binding and convulsant studies. Eur J Pharmacol (1978) 1.38
Smoking...harmful to the brain. Nature (1996) 1.37
Inhibition of noradrenaline uptake 2 in the isolated rat heart by steroids, clonidine and methoxylated phenylethylamines. Eur J Pharmacol (1972) 1.37
Enhancement of H-3-norepinephrine uptake in rat tissues by O-methylated metabolites of catecholamines. J Pharmacol Exp Ther (1966) 1.36
Subcellular distribution of endogenous and (3H) gamma-aminobutyric acid in rat cerebral cortex. J Neurochem (1969) 1.35
The uptake and storage of H3-norepinephrine in the reserpine-pretreated rat heart. J Pharmacol Exp Ther (1965) 1.30
Effects of surgical decentralization and nerve growth factor on the maturation of adrenergic neurons in a mouse sympathetic ganglion. J Neurochem (1972) 1.28
Glycine uptake in rat central nervous system slices and homogenates: evidence for different uptake systems in spinal cord and cerebral cortex. J Neurochem (1971) 1.24
Release and metabolism of substance P in rat hypothalamus. Nature (1976) 1.24
Regional studies of catecholamines in the rat brain. II. Rate of turnover of catecholamines in various brain regions. J Neurochem (1966) 1.23
Purification and characterisation of a membrane-bound substance-P-degrading enzyme from human brain. Eur J Biochem (1981) 1.22
Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type. Neurosci Lett (1980) 1.21
Calcium-dependent release of somatostatin and neurotensin from rat brain in vitro. Nature (1978) 1.21
Effects of 6-hydroxydopamine on noradrenaline-containing neurones in the rat brain. Nature (1969) 1.20
Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype. Proc Natl Acad Sci U S A (1992) 1.19
The metabolism of gamma-aminobutyric acid (GABA) in the lobster nervous system--uptake of GABA in the nerve-muscle preparations. J Neurochem (1968) 1.19
Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat. J Neurosci (1983) 1.18
Studies of the uptake of 3 H-gaba and ( 3 H)glycine in slices and homogenates of rat brain and spinal cord by electron microscopic autoradiography. Brain Res (1972) 1.18
Mechanism of inositol monophosphatase, the putative target of lithium therapy. Proc Natl Acad Sci U S A (1994) 1.18
Regional studies of catecholamines in the rat brain. IV. Effects of drugs on the disposition and metabolism of H3-norepinephrine and H3-dopamine. J Pharmacol Exp Ther (1966) 1.18
Localizing 3H-GABA in nerve terminals of rat cerebral cortex by electron microscopic autoradiography. Nature (1971) 1.18
Noradrenaline metabolizing enzymes in normal and sympathetically denervated vas deferens. J Neurochem (1971) 1.12
The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential. J Med Chem (1994) 1.12
Loss of pigmented dopamine-beta-hydroxylase positive cells from locus coeruleus in senile dementia of Alzheimer's type. Neurosci Lett (1983) 1.12
A quantitative comparison of the formation of synapses in the rat superior cervical sympathetic ganglion by its own and by foreign nerve fibres. Brain Res (1976) 1.10
The role of post-synaptic neurones in the biochemical maturation of presynaptic cholinergic nerve terminals in a mouse sympathetic ganglion. J Physiol (1972) 1.10
Effects of protriptyline on the depletion of catecholamines induced by 6-hydroxydopamine in the brain of the rat. J Pharm Pharmacol (1970) 1.10
Release of (3H)gamma-aminobutyric acid from glial cells in rat dorsal root ganglia. J Neurochem (1974) 1.09
The uptake of catechol amines at high perfusion concentrations in the rat isolated heart: A novel catechol amine uptake process. Br J Pharmacol Chemother (1965) 1.08
Synaptosomes: different populations storing catecholamines and gamma-aminobutyric acid in homogenates of rat brain. Nature (1968) 1.08
Dopamine selectively increases 3H-GABA release from slices of rat substantia nigra in vitro. Nature (1977) 1.08
Trans-synaptic regulation of tyrosine hydroxylase activity in adrenergic neurones: effect of potassium concentration on cultured sympathetic ganglia. Naunyn Schmiedebergs Arch Pharmacol (1972) 1.06
Neuronal degeneration in locus ceruleus and cortical correlates of Alzheimer disease. Alzheimer Dis Assoc Disord (1987) 1.06
Neuronal uptake processes for amines and amino acids. Adv Biochem Psychopharmacol (1970) 1.05
The substantia innominata in Alzheimer's disease: an histochemical and biochemical study of cholinergic marker enzymes. Neurosci Lett (1982) 1.05
Relative affinities of drugs acting at cholinoceptors in displacing agonist and antagonist radioligands: the NMS/Oxo-M ratio as an index of efficacy at cortical muscarinic receptors. Br J Pharmacol (1988) 1.05
Thermoregulation: effects of environmental temperature on turnover of hypothalamic norepinephrine. Science (1969) 1.03
Inhibition of the extraneuronal uptake of catecholamine in the isolated rat heart by cholesterol. Nat New Biol (1972) 1.02
Modification of an enzyme radiochemical assay procedure for noradrenaline. Biochem Pharmacol (1970) 1.02
Differences in the uptake, storage and metabolism of (+)- and (-)-noradrenaline. Br J Pharmacol (1971) 1.02
Effect of chlorpromazine and some of its metabolites on the dopamine-sensitive adenylate cyclase of rat brain striatum. J Pharm Pharmacol (1974) 1.02
Catecholamine-sensitive adenylate cyclases in nervous tissues. J Neurochem (1977) 1.02
Substance P. J Med Chem (1982) 1.01
Comparison of the effects of neuroleptic drugs on pre- and postsynaptic dopaminergic mechanisms in the rat striatum. Mol Pharmacol (1976) 1.00
Inhibition of the extraneuronal metabolism of noradrenaline in the isolated heart by adrenergic blocking agents. Nature (1967) 1.00
Stimulation of a dopamine-sensitive adenylate cyclase in homogenates of rat striatum by a metabolite of piribedil (ET 495). Naunyn Schmiedebergs Arch Pharmacol (1974) 1.00
Release of enkephalin from rat globus pallidus in vitro. Nature (1978) 1.00
Substance P: localization in synaptic vesicles in rat central nervous system. J Neurochem (1977) 0.99
Muscarinic cholinergic receptors in rat corpus striatum and regulation of guanosine cyclic 3',5'-monophosphate. Mol Pharmacol (1978) 0.99
Monoamine oxidase and catechol-O-methyl transferase activities in cat nictitating membrane and rat and guinea-pig vas deferens after sympathectomy. Br J Pharmacol (1968) 0.99
Vasoactive intestinal polypeptide (VIP): vesicular localization and potassium evoked release from rat hypothalamus. Brain Res (1978) 0.99
Vasopressin, oxytocin and neurophysins in the human brain and spinal cord. Brain Res (1984) 0.98
Characteristics of noradrenaline uptake in the iris ciliary body and other peripheral tissues of the rat. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1968) 0.98
Reduced glutamic-acid-decarboxylase activity of post-mortem brain in Huntington's chorea. Lancet (1973) 0.98
The Ferrier Lecture, 1983. Amino acids and peptides: fast and slow chemical signals in the nervous system? Proc R Soc Lond B Biol Sci (1984) 0.98
Calcitonin gene-related peptide: novel neuropeptide. Life Sci (1986) 0.97
Use of ADTN to define specific 3H-spirerone binding to receptors in brain. Nature (1978) 0.97
Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative. Proc Natl Acad Sci U S A (1990) 0.96
Dopamine receptors in the retina may all be linked to adenylate cyclase. Nature (1979) 0.96
Increased brain dopamine and dopamine receptors in schizophrenia. Arch Gen Psychiatry (1982) 0.96
Selective extraction of small and large molecules from the cerebrospinal fluid by Purkinje neurons. Science (1985) 0.96