Feeding low or pharmacological concentrations of zinc oxide changes the hepatic proteome profiles in weaned piglets.

PubWeight™: 0.78‹?›

🔗 View Article (PMC 3839893)

Published in PLoS One on November 25, 2013

Authors

Angelika Bondzio1, Robert Pieper, Christoph Gabler, Christoph Weise, Petra Schulze, Juergen Zentek, Ralf Einspanier

Author Affiliations

1: Institute of Veterinary Biochemistry, Freie Universität Berlin, Berlin, Germany.

Articles cited by this

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol (2002) 82.19

Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem (1996) 45.70

Molecular chaperones in the cytosol: from nascent chain to folded protein. Science (2002) 15.09

Mammalian zinc transport, trafficking, and signals. J Biol Chem (2006) 3.05

Mammalian zinc transporters: nutritional and physiologic regulation. Annu Rev Nutr (2009) 2.91

The development of the DIGE system: 2D fluorescence difference gel analysis technology. Anal Bioanal Chem (2005) 2.64

Heat shock genes - integrating cell survival and death. J Biosci (2007) 2.43

Zinc and human health: an update. Arch Toxicol (2011) 2.08

Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis. J Biol Chem (1997) 1.88

Regulatory role for the arginine-nitric oxide pathway in metabolism of energy substrates. J Nutr Biochem (2006) 1.77

Sp1 and its likes: biochemical and functional predictions for a growing family of zinc finger transcription factors. Ann N Y Acad Sci (1999) 1.59

Treatment of cirrhosis and liver failure in rats by hepatocyte xenotransplantation. Gastroenterology (2003) 1.48

Zinc supplementation prevents alcoholic liver injury in mice through attenuation of oxidative stress. Am J Pathol (2005) 1.47

Common themes and variations in the rhodanese superfamily. IUBMB Life (2007) 1.46

Iron, ferritin, and nutrition. Annu Rev Nutr (2004) 1.39

Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig. Proc Natl Acad Sci U S A (2002) 1.28

Influence of dietary zinc oxide and copper sulfate on the gastrointestinal ecosystem in newly weaned piglets. Appl Environ Microbiol (2005) 1.19

Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex. J Biol Chem (2002) 1.18

History of zinc as related to brain function. J Nutr (2000) 1.08

Aging and molecular chaperones. Exp Gerontol (2003) 1.08

Effects of intracellular zinc depletion on metallothionein and ZIP2 transporter expression and apoptosis. J Leukoc Biol (2001) 1.07

Dietary zinc deficiency induced-changes in the activity of enzymes and the levels of free radicals, lipids and protein electrophoretic behavior in growing rats. Toxicology (2002) 1.07

Heat shock response: hsp70 in environmental monitoring. J Biochem Mol Toxicol (2003) 1.06

Supplemental zinc reduced intestinal permeability by enhancing occludin and zonula occludens protein-1 (ZO-1) expression in weaning piglets. Br J Nutr (2009) 1.03

Apoptosis induced by chelation of intracellular zinc is associated with depletion of cellular reduced glutathione level in rat hepatocytes. Chem Biol Interact (2000) 1.01

Effect of dietary zinc deficiency on hematological and biochemical parameters and concentrations of zinc, copper, and iron in growing rats. Toxicology (2001) 1.01

Intracellular zinc movement and its effect on the carbohydrate metabolism of isolated rat hepatocytes. J Biol Chem (1996) 0.99

Zinc supplementation inhibits hepatic apoptosis in mice subjected to a long-term ethanol exposure. Exp Biol Med (Maywood) (2008) 0.98

Increased dietary zinc oxide changes the bacterial core and enterobacterial composition in the ileum of piglets. J Anim Sci (2011) 0.97

The role of serpins in the surveillance of the secretory pathway. Cell Mol Life Sci (2007) 0.97

Diosmectite-zinc oxide composite improves intestinal barrier function, modulates expression of pro-inflammatory cytokines and tight junction protein in early weaned pigs. Br J Nutr (2013) 0.95

Zinc and the liver: an active interaction. Dig Dis Sci (2007) 0.95

Update on zinc deficiency and excess in clinical pediatric practice. Ann Nutr Metab (2013) 0.95

ERp29, an unusual redox-inactive member of the thioredoxin family. Antioxid Redox Signal (2006) 0.95

Dietary supplementation with zinc oxide increases Igf-I and Igf-I receptor gene expression in the small intestine of weanling piglets. J Nutr (2006) 0.95

Effect of pharmacological concentrations of zinc oxide with or without the inclusion of an antibacterial agent on nursery pig performance. J Anim Sci (2001) 0.94

Antioxidant protection against organic and inorganic oxygen radicals by normal human plasma: the important primary role for iron-binding and iron-oxidising proteins. Biochim Biophys Acta (1993) 0.94

Proteomic analysis reveals altered expression of proteins related to glutathione metabolism and apoptosis in the small intestine of zinc oxide-supplemented piglets. Amino Acids (2009) 0.93

Regulation of metallothioneins and ZnT-1 transporter expression in human hepatoma cells HepG2 exposed to zinc and cadmium. Toxicol In Vitro (2009) 0.93

Enzymatic conversion of cyanide to thiocyanate. Am J Physiol (1948) 0.90

Dietary supplementation with zinc oxide stimulates ghrelin secretion from the stomach of young pigs. J Nutr Biochem (2008) 0.90

Endoplasmic reticulum protein 29 (ERp29): An emerging role in cancer. Int J Biochem Cell Biol (2010) 0.89

Rhodanese distribution in porcine (Sus scrofa) tissues. Comp Biochem Physiol B Biochem Mol Biol (2002) 0.89

Growth and plasma zinc responses of young pigs fed pharmacologic levels of zinc. J Anim Sci (1993) 0.89

Early- and traditionally weaned nursery pigs benefit from phase-feeding pharmacological concentrations of zinc oxide: effect on metallothionein and mineral concentrations. J Anim Sci (1999) 0.87

Impairment of cellular immunity is associated with overexpression of heat shock protein 70 in neonatal pigs with intrauterine growth retardation. Cell Stress Chaperones (2012) 0.86

A high amount of dietary zinc changes the expression of zinc transporters and metallothionein in jejunal epithelial cells in vitro and in vivo but does not prevent zinc accumulation in jejunal tissue of piglets. J Nutr (2013) 0.86

Zinc depletion reduced Egr-1 and HNF-3beta expression and apolipoprotein A-I promoter activity in Hep G2 cells. Am J Physiol Cell Physiol (2002) 0.85

Identification of differentially expressed proteins in ruminal epithelium in response to a concentrate-supplemented diet. Am J Physiol Gastrointest Liver Physiol (2011) 0.84

Differential expression of cyclooxygenase 1 and cyclooxygenase 2 in the bovine oviduct. J Endocrinol (2006) 0.83

Transferrin function in zinc absorption and transport. Proc Soc Exp Biol Med (1976) 0.83

Dose-dependent effects of dietary zinc oxide on bacterial communities and metabolic profiles in the ileum of weaned pigs. J Anim Physiol Anim Nutr (Berl) (2011) 0.82

Effect of zinc supplementation on type 2 diabetes parameters and liver metallothionein expressions in Wistar rats. J Physiol Biochem (2012) 0.82

Pharmacological zinc and phytase supplementation enhance metallothionein mRNA abundance and protein concentration in newly weaned pigs. J Nutr (2004) 0.82

Effects of zinc on epithelial barrier properties and viability in a human and a porcine intestinal cell culture model. Toxicol In Vitro (2012) 0.82

Zinc oxide-montmorillonite hybrid influences diarrhea, intestinal mucosal integrity, and digestive enzyme activity in weaned pigs. Biol Trace Elem Res (2012) 0.82

Activation of glycolysis by zinc is diminished in hepatocytes from metallothionein-null mice. Biol Trace Elem Res (2000) 0.81

Identification of metal-binding proteins in human hepatoma lines by immobilized metal affinity chromatography and mass spectrometry. Mol Cell Proteomics (2003) 0.81

Protection of zinc against tumor necrosis factor induced lethal inflammation depends on heat shock protein 70 and allows safe antitumor therapy. Cancer Res (2007) 0.80

Effect of feeding organic and inorganic sources of additional zinc on growth performance and zinc balance in nursery pigs. J Anim Sci (2002) 0.80

Zinc concentration in tissues and performance of weanling pigs fed pharmacological levels of zinc from ZnO, Zn-methionine, Zn-lysine, or ZnSO4. J Anim Sci (1996) 0.79

Gene expression profiling in hepatic tissue of newly weaned pigs fed pharmacological zinc and phytase supplemented diets. BMC Genomics (2008) 0.79

Ameliorative effects of soy 11S protein on liver damage and hyperlipidemia in alcohol-fed rats. Biol Pharm Bull (2004) 0.79

Slow binding of metal ions to pigeon liver malic enzyme: a general case. Biochemistry (2000) 0.78

Effects of transportation on expression of Hsp90, Hsp70, Hsp27 and αB-crystallin in the pig stomach. Vet Rec (2011) 0.78

Zinc deficiency decreases plasma level and hepatic mRNA abundance of apolipoprotein A-I in rats and hamsters. Am J Physiol (1998) 0.78

Apolipoprotein A-I gene expression is regulated by cellular zinc status in hep G2 cells. Am J Physiol (1999) 0.77

Hepatic responses to dietary stress in zinc- and metallothionein-deficient mice. Exp Biol Med (Maywood) (2006) 0.77

Activities of purine catabolism related enzymes in zinc deficiency: relationship to T-lymphocyte dysfunction and hyperammonemia. Int J Vitam Nutr Res (1991) 0.77

Dietary pharmacological or excess zinc and phytase effects on tissue mineral concentrations, metallothionein, and apparent mineral retention in the newly weaned pig. Biol Trace Elem Res (2005) 0.76

Serosal zinc attenuate serotonin and vasoactive intestinal peptide induced secretion in piglet small intestinal epithelium in vitro. Comp Biochem Physiol A Mol Integr Physiol (2007) 0.76

Zinc, vanadate and selenate inhibit the tri-iodothyronine-induced expression of fatty acid synthase and malic enzyme in chick-embryo hepatocytes in culture. Biochem J (1994) 0.76

Role of d electrons in the zinc-blende semiconductors ZnS, ZnSe, and ZnTe. Phys Rev B Condens Matter (1995) 0.76

Effects of metal-ion binding on rhodanese activity. Arch Biochem Biophys (1978) 0.76

Simultaneous multiple element detection by particle beam/hollow cathode-optical emission spectroscopy as a tool for metallomic studies: determinations of metal binding with apo-transferrin. Metallomics (2009) 0.76

Articles by these authors

Discovering microRNAs from deep sequencing data using miRDeep. Nat Biotechnol (2008) 10.17

Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin. Mol Cell (2003) 3.47

Ninety-day oral toxicity studies on two genetically modified maize MON810 varieties in Wistar Han RCC rats (EU 7th Framework Programme project GRACE). Arch Toxicol (2014) 2.91

Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type II. J Exp Med (2004) 2.73

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42. EMBO J (2007) 2.61

Two-dimensional proteome reference map of Prototheca zopfii revealed reduced metabolism and enhanced signal transduction as adaptation to an infectious life style. Proteomics (2013) 1.54

miR-Q: a novel quantitative RT-PCR approach for the expression profiling of small RNA molecules such as miRNAs in a complex sample. BMC Mol Biol (2008) 1.42

Insulin attenuates the systemic inflammatory response in endotoxemic rats. Endocrinology (2004) 1.39

Integrated microRNA-mRNA-analysis of human monocyte derived macrophages upon Mycobacterium avium subsp. hominissuis infection. PLoS One (2011) 1.35

Role of amyloid-beta glycine 33 in oligomerization, toxicity, and neuronal plasticity. J Neurosci (2009) 1.34

Deciphering the porcine intestinal microRNA transcriptome. BMC Genomics (2010) 1.30

Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP. J Biol Chem (2008) 1.29

Direct binding of INHAT to H3 tails disrupted by modifications. J Biol Chem (2004) 1.22

Insulin attenuates the systemic inflammatory response to thermal trauma. Mol Med (2002) 1.22

Aberrant amyloid precursor protein (APP) processing in hereditary forms of Alzheimer disease caused by APP familial Alzheimer disease mutations can be rescued by mutations in the APP GxxxG motif. J Biol Chem (2010) 1.21

Nonstarch polysaccharides modulate bacterial microbiota, pathways for butyrate production, and abundance of pathogenic Escherichia coli in the pig gastrointestinal tract. Appl Environ Microbiol (2010) 1.20

Dependence of ORC silencing function on NatA-mediated Nalpha acetylation in Saccharomyces cerevisiae. Mol Cell Biol (2004) 1.19

Characterization of new members of the group 3 outer membrane protein family of Brucella spp. Infect Immun (2003) 1.19

The broader context of antibiotic resistance: zinc feed supplementation of piglets increases the proportion of multi-resistant Escherichia coli in vivo. Int J Med Microbiol (2013) 1.09

The murine goblet cell protein mCLCA3 is a zinc-dependent metalloprotease with autoproteolytic activity. Mol Cells (2011) 1.04

The amyloid precursor protein C-terminal fragment C100 occurs in monomeric and dimeric stable conformations and binds γ-secretase modulators. Biochemistry (2011) 1.03

Intestinal expression of TFF and related genes during postnatal development in a piglet probiotic trial. Cell Physiol Biochem (2009) 1.03

Monozygotic twin model reveals novel embryo-induced transcriptome changes of bovine endometrium in the preattachment period. Biol Reprod (2005) 1.02

Short-term weightlessness produced by parabolic flight maneuvers altered gene expression patterns in human endothelial cells. FASEB J (2011) 1.00

ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kappaB activity and AT1 receptor expression. Biochem Biophys Res Commun (2004) 1.00

Intestinal Salmonella typhimurium infection leads to miR-29a induced caveolin 2 regulation. PLoS One (2013) 0.99

Triblock copolymers: synthesis, characterization, and delivery of a model protein. Int J Pharm (2004) 0.98

Degradation of Cry1Ab protein from genetically modified maize in the bovine gastrointestinal tract. J Agric Food Chem (2005) 0.97

Shedding of the transferrin receptor is mediated constitutively by an integral membrane metalloprotease sensitive to tumor necrosis factor alpha protease inhibitor-2. J Biol Chem (2002) 0.95

Differential gene regulation under altered gravity conditions in follicular thyroid cancer cells: relationship between the extracellular matrix and the cytoskeleton. Cell Physiol Biochem (2011) 0.95

Changes in the diversity of pig ileal lactobacilli around weaning determined by means of 16S rRNA gene amplification and denaturing gradient gel electrophoresis. FEMS Microbiol Ecol (2007) 0.95

Chemoselective Staudinger-phosphite reaction of azides for the phosphorylation of proteins. Angew Chem Int Ed Engl (2009) 0.94

Proteome of metastatic canine mammary carcinomas: similarities to and differences from human breast cancer. J Proteome Res (2010) 0.93

Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor. J Biol Chem (2012) 0.93

Parenteral long-acting amoxicillin reduces intestinal bacterial community diversity in piglets even 5 weeks after the administration. ISME J (2007) 0.92

Molecular cloning, expression and isolation of ferritins from two tick species--Ornithodoros moubata and Ixodes ricinus. Insect Biochem Mol Biol (2003) 0.92

Prenatal testosterone excess alters Sertoli and germ cell number and testicular FSH receptor expression in rams. Am J Physiol Endocrinol Metab (2010) 0.90

Concatameric cloning of porcine microRNA molecules after assembly PCR. Biochem Biophys Res Commun (2008) 0.90

Expression of hyaluronan synthases and corresponding hyaluronan receptors is differentially regulated during oocyte maturation in cattle. Biol Reprod (2003) 0.90

Selected pro-inflammatory factor transcripts in bovine endometrial epithelial cells are regulated during the oestrous cycle and elevated in case of subclinical or clinical endometritis. Reprod Fertil Dev (2010) 0.90

Release of periplasmic proteins of Brucella suis upon acidic shock involves the outer membrane protein Omp25. Infect Immun (2004) 0.89

A fast, simple and sensitive method for the detection and quantification of detergent-resistant membranes. J Immunol Methods (2002) 0.89

Quantification and accurate normalisation of small RNAs through new custom RT-qPCR arrays demonstrates Salmonella-induced microRNAs in human monocytes. BMC Genomics (2012) 0.89

The insect metalloproteinase inhibitor gene of the lepidopteran Galleria mellonella encodes two distinct inhibitors. Biol Chem (2007) 0.89

Tumor necrosis factor alpha in the bovine oviduct during the estrous cycle: messenger RNA expression and effect on secretion of prostaglandins, endothelin-1, and angiotensin II. Biol Reprod (2003) 0.88

The tick plasma lectin, Dorin M, is a fibrinogen-related molecule. Insect Biochem Mol Biol (2006) 0.88

Relaxin supports implantation and early pregnancy in the marmoset monkey. Ann N Y Acad Sci (2009) 0.88

Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffolds. Chem Commun (Camb) (2011) 0.87

Identification of PSF as a protein kinase Calpha-binding protein in the cell nucleus. J Cell Biochem (2002) 0.87

The impact of high dietary zinc oxide on the development of the intestinal microbiota in weaned piglets. FEMS Microbiol Ecol (2013) 0.87

Feeding of the probiotic bacterium Enterococcus faecium NCIMB 10415 differentially affects shedding of enteric viruses in pigs. Vet Res (2012) 0.86

Long-term culture of primary porcine oviduct epithelial cells: validation of a comprehensive in vitro model for reproductive science. Theriogenology (2013) 0.86

A high amount of dietary zinc changes the expression of zinc transporters and metallothionein in jejunal epithelial cells in vitro and in vivo but does not prevent zinc accumulation in jejunal tissue of piglets. J Nutr (2013) 0.86

Performance, organ zinc concentration, jejunal brush border membrane enzyme activities and mRNA expression in piglets fed with different levels of dietary zinc. Arch Anim Nutr (2013) 0.85

In vitro mimicking of estrous cycle stages in porcine oviduct epithelium cells: estradiol and progesterone regulate differentiation, gene expression, and cellular function. Biol Reprod (2013) 0.85

Interleukin-4 supports interleukin-12-induced proliferation and interferon-gamma secretion in human activated lymphoblasts and T helper type 1 cells. Immunology (2006) 0.84

Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers. EMBO Mol Med (2012) 0.84

Time-dependent mRNA expression of selected pro-inflammatory factors in the endometrium of primiparous cows postpartum. Reprod Biol Endocrinol (2010) 0.84

Identification of differentially expressed proteins in ruminal epithelium in response to a concentrate-supplemented diet. Am J Physiol Gastrointest Liver Physiol (2011) 0.84

Glycine-terminated dendritic amphiphiles for nonviral gene delivery. Biomacromolecules (2012) 0.83

Effect of alginate and inulin on intestinal microbial ecology of weanling pigs reared under different husbandry conditions. FEMS Microbiol Ecol (2009) 0.83

Differential expression of cyclooxygenase 1 and cyclooxygenase 2 in the bovine oviduct. J Endocrinol (2006) 0.83

Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study. Acta Neuropathol Commun (2014) 0.82

Inhibition of sphingolipid synthesis impairs cellular activation, cytokine production and proliferation in human lymphocytes. Biochem Pharmacol (2005) 0.82

Establishment and characterization of a differentiated epithelial cell culture model derived from the porcine cervix uteri. BMC Vet Res (2012) 0.82

Is there a malignant progression associated with a linear change in protein expression levels from normal canine mammary gland to metastatic mammary tumors? J Proteome Res (2011) 0.82

BMP2-induced chemotaxis requires PI3K p55γ/p110α-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5β recruitment at the cytocortex. BMC Biol (2014) 0.82

Modulation of α-synuclein fibrillization by ring-fused 2-pyridones: templation and inhibition involve oligomers with different structure. Arch Biochem Biophys (2013) 0.82

Differences in the hepatic signal transcription pathway and cytokine expression between thermal injury and sepsis. Shock (2003) 0.81

Processing of the human transferrin receptor at distinct positions within the stalk region by neutrophil elastase and cathepsin G. Biol Chem (2002) 0.81

Azide phosphoramidite in direct synthesis of azide-modified oligonucleotides. Org Lett (2014) 0.81

Feeding the probiotic Enterococcus faecium strain NCIMB 10415 to piglets specifically reduces the number of Escherichia coli pathotypes that adhere to the gut mucosa. Appl Environ Microbiol (2013) 0.81

Nonstarch polysaccharide-degrading enzymes alter the microbial community and the fermentation patterns of barley cultivars and wheat products in an in vitro model of the porcine gastrointestinal tract. FEMS Microbiol Ecol (2011) 0.80

Intestinal concentrations of free and encapsulated dietary medium-chain fatty acids and effects on gastric microbial ecology and bacterial metabolic products in the digestive tract of piglets. Arch Anim Nutr (2012) 0.80

Expression of epidermal growth factor receptor (EGF-R), vascular endothelial growth factor receptor (VEGF-R) and fibroblast growth factor receptor (FGF-R) systems in porcine oviduct and endometrium during the time of implantation. J Reprod Dev (2004) 0.80

Integrin alpha3beta1 interacts with I1PP2A/lanp and phosphatase PP1. J Neurosci Res (2006) 0.79

Characterization and primary structures of bovine and porcine thyroxine-binding globulin. Mol Cell Endocrinol (2002) 0.79

Anti-HLA-DR-triggered monocytes mediate in vitro T cell anergy. Int Immunol (2008) 0.79

Molecular cloning, structure and bait region splice variants of alpha2-macroglobulin from the soft tick Ornithodoros moubata. Insect Biochem Mol Biol (2003) 0.79

Lability landscape and protease resistance of human insulin amyloid: a new insight into its molecular properties. J Mol Biol (2009) 0.79

Regulation of endometrial fibroblast growth factor 7 (FGF-7) and its receptor FGFR2IIIb in gilts after sex steroid replacements, and during the estrous cycle and early gestation. J Reprod Dev (2005) 0.79

Changes in the expression of pluripotency-associated genes during preimplantation and peri-implantation stages in bovine cloned and in vitro produced embryos. Zygote (2010) 0.79

Copper is required for prion protein-associated superoxide dismutase-I activity in Pichia pastoris. FEBS J (2007) 0.79

Structural analysis of microRNA-target interaction by sequential seed mutagenesis and stem-loop 3' RACE. PLoS One (2013) 0.79

Cry1Ab treatment has no effects on viability of cultured porcine intestinal cells, but triggers Hsp70 expression. PLoS One (2013) 0.79

Towards structure determination of neurotoxin II bound to nicotinic acetylcholine receptor: a solid-state NMR approach. FEBS Lett (2004) 0.78

Biological diversity of yeasts in the gastrointestinal tract of weaned piglets kept under different farm conditions. FEMS Yeast Res (2008) 0.78

Effects of feeding sunflower oil or seal blubber oil to horses with recurrent airway obstruction. Can J Vet Res (2007) 0.78

Differential gene expression in bovine elongated (Day 17) embryos produced by somatic cell nucleus transfer and in vitro fertilization. Theriogenology (2010) 0.78

Cytomegalovirus expresses the chemokine homologue vXCL1 capable of attracting XCR1+ CD4- dendritic cells. J Virol (2013) 0.78

Small structural differences of targeted anti-tumor toxins result in strong variation of protein expression. Protein Expr Purif (2013) 0.77