Published in J Biol Chem on April 19, 2004
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The WD40-repeat protein Pwp1p associates in vivo with 25S ribosomal chromatin in a histone H4 tail-dependent manner. Nucleic Acids Res (2006) 0.83
NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle. Nucleic Acids Res (2010) 0.81
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Active genes are tri-methylated at K4 of histone H3. Nature (2002) 15.68
Histone H3 lysine 4 methylation patterns in higher eukaryotic genes. Nat Cell Biol (2003) 8.82
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Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature (2011) 8.29
Cancer epigenetics: from mechanism to therapy. Cell (2012) 7.74
Methylation of histone H3 Lys 4 in coding regions of active genes. Proc Natl Acad Sci U S A (2002) 7.67
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J (2002) 6.37
Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9. Nature (2002) 6.09
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science (2002) 6.05
New nomenclature for chromatin-modifying enzymes. Cell (2007) 5.34
The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains. Trends Biochem Sci (2003) 5.19
Histone deimination antagonizes arginine methylation. Cell (2004) 5.19
Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell (2004) 4.99
Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes. J Biol Chem (2005) 4.78
The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation. J Biol Chem (2002) 4.70
JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin. Nature (2009) 4.60
Histone arginine methylation regulates pluripotency in the early mouse embryo. Nature (2007) 4.55
The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res (2003) 4.36
EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell (2003) 4.33
An operational definition of epigenetics. Genes Dev (2009) 4.26
Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains. J Biol Chem (2005) 4.20
Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nat Cell Biol (2006) 3.65
Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin. Mol Cell (2003) 3.47
Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation. Nature (2007) 3.32
Nucleosome-interacting proteins regulated by DNA and histone methylation. Cell (2010) 3.25
Histone methylation: dynamic or static? Cell (2002) 3.12
Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J (2004) 2.94
Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development (2003) 2.91
Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex. J Biol Chem (2002) 2.89
Targeting epigenetic readers in cancer. N Engl J Med (2012) 2.86
Methylation at arginine 17 of histone H3 is linked to gene activation. EMBO Rep (2001) 2.83
Unsafe SETs: histone lysine methyltransferases and cancer. Trends Biochem Sci (2002) 2.80
Crosstalk between CARM1 methylation and CBP acetylation on histone H3. Curr Biol (2002) 2.78
GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42. EMBO J (2007) 2.61
Reversing histone methylation. Nature (2005) 2.57
The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase. EMBO J (2002) 2.56
cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site. Curr Biol (2002) 2.27
Dynamic distribution of the replacement histone variant H3.3 in the mouse oocyte and preimplantation embryos. Int J Dev Biol (2006) 2.17
The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development. Blood (2009) 1.97
Proline isomerization of histone H3 regulates lysine methylation and gene expression. Cell (2006) 1.93
Heterochromatin formation in the mouse embryo requires critical residues of the histone variant H3.3. Nat Cell Biol (2010) 1.89
Histone methylation: recognizing the methyl mark. Methods Enzymol (2004) 1.85
Methylation of H3 lysine 4 at euchromatin promotes Sir3p association with heterochromatin. J Biol Chem (2004) 1.78
The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4. J Mol Biol (2012) 1.69
Regulation of histone H3 lysine 56 acetylation in Schizosaccharomyces pombe. J Biol Chem (2007) 1.65
Two-dimensional proteome reference map of Prototheca zopfii revealed reduced metabolism and enhanced signal transduction as adaptation to an infectious life style. Proteomics (2013) 1.54
Acetylation of beta-catenin by CREB-binding protein (CBP). J Biol Chem (2002) 1.47
Human RNA methyltransferase BCDIN3D regulates microRNA processing. Cell (2012) 1.46
Dnmt3L is a transcriptional repressor that recruits histone deacetylase. Nucleic Acids Res (2002) 1.45
Histone methylation defines epigenetic asymmetry in the mouse zygote. Int J Dev Biol (2002) 1.41
Differential expression of selected histone modifier genes in human solid cancers. BMC Genomics (2006) 1.39
DNA methyltransferases get connected to chromatin. Trends Genet (2002) 1.38
A chromodomain switch mediated by histone H3 Lys 4 acetylation regulates heterochromatin assembly. Genes Dev (2010) 1.37
Role of amyloid-beta glycine 33 in oligomerization, toxicity, and neuronal plasticity. J Neurosci (2009) 1.34
Mechanisms of P/CAF auto-acetylation. Nucleic Acids Res (2003) 1.32
Histone H3 tail clipping regulates gene expression. Nat Struct Mol Biol (2008) 1.30
Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP. J Biol Chem (2008) 1.29
Phosphorylation of histone H3 Thr-45 is linked to apoptosis. J Biol Chem (2009) 1.26
LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease. Nat Cell Biol (2010) 1.25
Aberrant amyloid precursor protein (APP) processing in hereditary forms of Alzheimer disease caused by APP familial Alzheimer disease mutations can be rescued by mutations in the APP GxxxG motif. J Biol Chem (2010) 1.21
Dependence of ORC silencing function on NatA-mediated Nalpha acetylation in Saccharomyces cerevisiae. Mol Cell Biol (2004) 1.19
Characterization of new members of the group 3 outer membrane protein family of Brucella spp. Infect Immun (2003) 1.19
Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity. Mol Cancer Ther (2005) 1.15
A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription. Mol Cell Biol (2003) 1.15
ALKBH1 is a histone H2A dioxygenase involved in neural differentiation. Stem Cells (2012) 1.09
Heritable gene repression through the action of a directed DNA methyltransferase at a chromosomal locus. J Biol Chem (2008) 1.08
Amplification of the BRCA2 pathway gene EMSY in sporadic breast cancer is related to negative outcome. Clin Cancer Res (2004) 1.08
The murine goblet cell protein mCLCA3 is a zinc-dependent metalloprotease with autoproteolytic activity. Mol Cells (2011) 1.04
The amyloid precursor protein C-terminal fragment C100 occurs in monomeric and dimeric stable conformations and binds γ-secretase modulators. Biochemistry (2011) 1.03
Distinct transcriptional outputs associated with mono- and dimethylated histone H3 arginine 2. Nat Struct Mol Biol (2009) 1.03
Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription. Elife (2014) 1.01
The non-coding snRNA 7SK controls transcriptional termination, poising, and bidirectionality in embryonic stem cells. Genome Biol (2013) 1.00
Crystal structure of the ENT domain of human EMSY. J Mol Biol (2005) 0.97
Shedding of the transferrin receptor is mediated constitutively by an integral membrane metalloprotease sensitive to tumor necrosis factor alpha protease inhibitor-2. J Biol Chem (2002) 0.95
Three distinct patterns of histone H3Y41 phosphorylation mark active genes. Cell Rep (2012) 0.95
Chemoselective Staudinger-phosphite reaction of azides for the phosphorylation of proteins. Angew Chem Int Ed Engl (2009) 0.94
Proteome of metastatic canine mammary carcinomas: similarities to and differences from human breast cancer. J Proteome Res (2010) 0.93
Histone H3 lysine 4 methylation is associated with the transcriptional reprogramming efficiency of somatic nuclei by oocytes. Epigenetics Chromatin (2010) 0.93
Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor. J Biol Chem (2012) 0.93
Molecular cloning, expression and isolation of ferritins from two tick species--Ornithodoros moubata and Ixodes ricinus. Insect Biochem Mol Biol (2003) 0.92
Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia. PLoS One (2011) 0.91
Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69. EMBO Rep (2005) 0.90