Published in Front Genet on December 03, 2013
eMERGEing progress in genomics-the first seven years. Front Genet (2014) 1.30
PheKB: a catalog and workflow for creating electronic phenotype algorithms for transportability. J Am Med Inform Assoc (2016) 1.10
Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis. Front Genet (2014) 1.06
Desiderata for computable representations of electronic health records-driven phenotype algorithms. J Am Med Inform Assoc (2015) 1.04
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet (2015) 0.94
Energy homeostasis genes and breast cancer risk: The influence of ancestry, body size, and menopausal status, the breast cancer health disparities study. Cancer Epidemiol (2015) 0.84
Insights into the Genetic Susceptibility to Type 2 Diabetes from Genome-Wide Association Studies of Obesity-Related Traits. Curr Diab Rep (2015) 0.81
The foundation of precision medicine: integration of electronic health records with genomics through basic, clinical, and translational research. Front Genet (2015) 0.78
Genome-wide association study for the interaction between BMR and BMI in obese Korean women including overweight. Nutr Res Pract (2015) 0.76
Association of gene coding variation and resting metabolic rate in a multi-ethnic sample of children and adults. BMC Obes (2017) 0.75
BIOFILTER AS A FUNCTIONAL ANNOTATION PIPELINE FOR COMMON AND RARE COPY NUMBER BURDEN. Pac Symp Biocomput (2016) 0.75
Association of timing of menarche with depressive symptoms and depression in adolescence: Mendelian randomisation study. Br J Psychiatry (2016) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatrics (2007) 23.88
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics (2010) 21.21
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Obesity as a medical problem. Nature (2000) 15.12
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet (2007) 14.99
LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics (2010) 13.54
Genetic and environmental factors in relative body weight and human adiposity. Behav Genet (1997) 12.07
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science (2007) 9.86
The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies. BMC Med Genomics (2011) 9.20
Genotype imputation with thousands of genomes. G3 (Bethesda) (2011) 8.77
Overexpression of Fto leads to increased food intake and results in obesity. Nat Genet (2010) 4.37
A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene. PLoS Genet (2009) 2.68
Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure. Obesity (Silver Spring) (2008) 2.68
Chapter 11: Genome-wide association studies. PLoS Comput Biol (2012) 2.46
Life course variations in the associations between FTO and MC4R gene variants and body size. Hum Mol Genet (2009) 2.22
Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations. Am J Hum Genet (2009) 2.09
Variation in the FTO gene influences food intake but not energy expenditure. Exp Clin Endocrinol Diabetes (2008) 1.96
Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development. PLoS Genet (2011) 1.82
Increasing heritability of BMI and stronger associations with the FTO gene over childhood. Obesity (Silver Spring) (2008) 1.77
Genetic determinants of common obesity and their value in prediction. Best Pract Res Clin Endocrinol Metab (2012) 1.76
Adipose tissue collagen VI in obesity. J Clin Endocrinol Metab (2009) 1.70
The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PLoS One (2010) 1.67
The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels. Eur J Hum Genet (2010) 1.45
The FTO obesity gene. Genotyping and gene expression analysis in morbidly obese patients. Obes Surg (2008) 1.31
The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimer's disease risk: a prospective cohort study. J Alzheimers Dis (2011) 1.30
Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling. J Biol Chem (2010) 1.26
Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis. PLoS Biol (2007) 1.21
A variant in FTO shows association with melanoma risk not due to BMI. Nat Genet (2013) 1.17
A common variant of the FTO gene is associated with not only increased adiposity but also elevated blood pressure in French Canadians. Circ Cardiovasc Genet (2009) 1.05
Contribution of 32 GWAS-identified common variants to severe obesity in European adults referred for bariatric surgery. PLoS One (2013) 1.01
Expression of collagen VI α5 and α6 chains in human muscle and in Duchenne muscular dystrophy-related muscle fibrosis. Matrix Biol (2011) 0.99
Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome: a systematic review and meta-analysis. Diabetologia (2012) 0.93
A comprehensive analysis of the COL29A1 gene does not support a role in eczema. J Allergy Clin Immunol (2011) 0.78