Lupus risk variants in the PXK locus alter B-cell receptor internalization.

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Published in Front Genet on January 08, 2015

Authors

Samuel E Vaughn1, Corinne Foley2, Xiaoming Lu3, Zubin H Patel1, Erin E Zoller3, Albert F Magnusen3, Adrienne H Williams4, Julie T Ziegler4, Mary E Comeau4, Miranda C Marion4, Stuart B Glenn5, Adam Adler5, Nan Shen6, Swapan Nath5, Anne M Stevens7, Barry I Freedman8, Betty P Tsao9, Chaim O Jacob10, Diane L Kamen11, Elizabeth E Brown12, Gary S Gilkeson11, Graciela S Alarcón13, John D Reveille14, Juan-Manuel Anaya15, Judith A James16, Kathy L Moser5, Lindsey A Criswell17, Luis M Vilá18, Marta E Alarcón-Riquelme19, Michelle Petri20, R Hal Scofield21, Robert P Kimberly13, Rosalind Ramsey-Goldman22, Young Binjoo23, Jeongim Choi23, Sang-Cheol Bae23, Susan A Boackle24, Timothy J Vyse25, Joel M Guthridge5, Bahram Namjou3, Patrick M Gaffney5, Carl D Langefeld4, Kenneth M Kaufman26, Jennifer A Kelly5, Isaac T W Harley1, John B Harley26, Leah C Kottyan26

Author Affiliations

1: Immunology Graduate Program and Medical Scientist Training Program, University of Cincinnati College of Medicine Cincinnati, OH, USA ; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center Cincinnati, OH, USA.
2: Spelman College Atlanta, GA, USA.
3: Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center Cincinnati, OH, USA.
4: Center for Public Health Genomics and the Department of Biostatistical Sciences, Wake Forest School of Medicine Winston-Salem, NC, USA.
5: Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation Oklahoma City, OK, USA.
6: Immunology Graduate Program and Medical Scientist Training Program, University of Cincinnati College of Medicine Cincinnati, OH, USA ; Joint Molecular Rheumatology Laboratory of the Institute of Health Sciences and Shanghai Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institutes for Biological Sciences, and Chinese Academy of Sciences Shanghai, China.
7: Center for Immunity and Immunotherapies, Seattle Children's Research Institute Seattle, WA, USA ; Division of Rheumatology, Department of Pediatrics, University of Washington Seattle, WA, USA.
8: Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine Winston-Salem, NC, USA.
9: Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles Los Angeles, CA, USA.
10: Department of Medicine, Keck School of Medicine, University of Southern California Los Angeles, CA, USA.
11: Division of Rheumatology, Medical University of South Carolina Charleston, SC, USA.
12: Department of Epidemiology, University of Alabama at Birmingham Birmingham, AL, USA ; Department of Medicine, University of Alabama at Birmingham Birmingham, AL, USA.
13: Department of Medicine, University of Alabama at Birmingham Birmingham, AL, USA.
14: Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston Houston, TX, USA.
15: Center for Autoimmune Disease Research, Universidad del Rosario Bogota, Colombia.
16: Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation Oklahoma City, OK, USA ; Department of Medicine, University of Oklahoma Health Sciences Center Oklahoma City, OK, USA.
17: Rosalind Russell/Ephraim P Engleman Rheumatology Research Research Center, Department of Medicine, University of California, San Francisco San Francisco, CA, USA.
18: Division of Rheumatology, Department of Medicine, University of Puerto Rico Medical Sciences Campus San Juan, PR, USA.
19: Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation Oklahoma City, OK, USA ; Center for Genomics and Oncological Research, Pfizer-University of Granada-Junta de Andalucia Granada, Spain.
20: Department of Medicine, Johns Hopkins University School of Medicine Baltimore, MD, USA.
21: Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation Oklahoma City, OK, USA ; Department of Medicine, University of Oklahoma Health Sciences Center Oklahoma City, OK, USA ; United States Department of Veterans Affairs Medical Center Oklahoma City, OK, USA.
22: Division of Rheumatology, Feinberg School of Medicine, Northwestern University Chicago, IL, USA.
23: Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases Seoul, Korea.
24: Division of Rheumatology, University of Colorado School of Medicine Aurora, CO, USA.
25: Divisions of Genetics and Molecular Medicine and Immunology, King's College London London, UK.
26: Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center Cincinnati, OH, USA ; United States Department of Veterans Affairs Medical Center Cincinnati, OH, USA.

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