Published in Nucleic Acids Res on January 16, 2014
Regulation of axon regeneration by the RNA repair and splicing pathway. Nat Neurosci (2015) 1.47
tRNA fragments in human health and disease. FEBS Lett (2014) 1.41
The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells. EMBO J (2014) 1.15
Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors. Nature (2014) 1.05
Handling tRNA introns, archaeal way and eukaryotic way. Front Genet (2014) 0.91
Characterization of 3'-Phosphate RNA Ligase Paralogs RtcB1, RtcB2, and RtcB3 from Myxococcus xanthus Highlights DNA and RNA 5'-Phosphate Capping Activity of RtcB3. J Bacteriol (2015) 0.85
RNA ligation in neurons by RtcB inhibits axon regeneration. Proc Natl Acad Sci U S A (2015) 0.82
Analysis of two domains with novel RNA-processing activities throws light on the complex evolution of ribosomal RNA biogenesis. Front Genet (2014) 0.81
Coevolution of RtcB and Archease created a multiple-turnover RNA ligase. RNA (2015) 0.77
Cutting, dicing, healing and sealing: the molecular surgery of tRNA. Wiley Interdiscip Rev RNA (2015) 0.76
Archaeal Nucleic Acid Ligases and Their Potential in Biotechnology. Archaea (2015) 0.76
Structure of RNA 3'-phosphate cyclase bound to substrate RNA. RNA (2014) 0.75
RNA damage in biological conflicts and the diversity of responding RNA repair systems. Nucleic Acids Res (2016) 0.75
Functional analysis of the mammalian RNA ligase for IRE1 in the unfolded protein response. Biosci Rep (2017) 0.75
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr D Biol Crystallogr (2010) 108.52
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids. Nucleic Acids Res (2007) 37.31
Regulation of cellular metabolism by protein lysine acetylation. Science (2010) 10.55
Enzymatic breakage and joining of deoxyribonucleic acid. VI. Further purification and properties of polynucleotide ligase from Escherichia coli infected with bacteriophage T4. J Biol Chem (1968) 7.09
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature (1997) 5.08
Allosteric activators of glucokinase: potential role in diabetes therapy. Science (2003) 3.97
A mechanism for all polymerases. Nature (1998) 3.79
DOOR: a database for prokaryotic operons. Nucleic Acids Res (2008) 3.50
Structure and function of the transcription elongation factor GreB bound to bacterial RNA polymerase. Cell (2003) 3.14
The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates. Nature (2006) 2.86
tRNA splicing. J Biol Chem (1998) 2.77
HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Science (2011) 2.03
Protocols for production of selenomethionine-labeled proteins in 2-L polyethylene terephthalate bottles using auto-induction medium. Protein Expr Purif (2005) 2.02
Donation of catalytic residues to RNA polymerase active center by transcription factor Gre. Proc Natl Acad Sci U S A (2003) 1.88
RtcB is the RNA ligase component of an Escherichia coli RNA repair operon. J Biol Chem (2011) 1.82
GeConT: gene context analysis. Bioinformatics (2004) 1.68
Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity. J Biol Chem (2007) 1.65
Archaeal 3'-phosphate RNA splicing ligase characterization identifies the missing component in tRNA maturation. Proc Natl Acad Sci U S A (2011) 1.65
Characterization of the Escherichia coli RNA 3'-terminal phosphate cyclase and its sigma54-regulated operon. J Biol Chem (1998) 1.63
Novel mechanism of RNA repair by RtcB via sequential 2',3'-cyclic phosphodiesterase and 3'-Phosphate/5'-hydroxyl ligation reactions. J Biol Chem (2011) 1.60
RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates. Proc Natl Acad Sci U S A (2012) 1.51
Protein lysine acylation and cysteine succination by intermediates of energy metabolism. ACS Chem Biol (2012) 1.49
Reconstituting bacterial RNA repair and modification in vitro. Science (2009) 1.45
Genome-scale analysis of gene function in the hydrogenotrophic methanogenic archaeon Methanococcus maripaludis. Proc Natl Acad Sci U S A (2013) 1.21
The sequential 2',3'-cyclic phosphodiesterase and 3'-phosphate/5'-OH ligation steps of the RtcB RNA splicing pathway are GTP-dependent. Nucleic Acids Res (2012) 1.19
Diversity and roles of (t)RNA ligases. Cell Mol Life Sci (2012) 1.18
Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH. Proc Natl Acad Sci U S A (2012) 1.14
Structures of the noncanonical RNA ligase RtcB reveal the mechanism of histidine guanylylation. Biochemistry (2013) 1.12
A protein phosphorylation switch at the conserved allosteric site in GP. Science (1996) 1.08
Kinetic characterization of single strand break ligation in duplex DNA by T4 DNA ligase. J Biol Chem (2011) 0.99
Archease from Pyrococcus abyssi improves substrate specificity and solubility of a tRNA m5C methyltransferase. J Biol Chem (2007) 0.95
The SHS2 module is a common structural theme in functionally diverse protein groups, like Rpb7p, FtsA, GyrI, and MTH1598/TM1083 superfamilies. Proteins (2004) 0.95
Kinetic mechanism of human DNA ligase I reveals magnesium-dependent changes in the rate-limiting step that compromise ligation efficiency. J Biol Chem (2011) 0.92
tRNA ligase catalyzes the GTP-dependent ligation of RNA with 3'-phosphate and 5'-hydroxyl termini. Biochemistry (2012) 0.88
Predicted role for the archease protein family based on structural and sequence analysis of TM1083 and MTH1598, two proteins structurally characterized through structural genomics efforts. Proteins (2004) 0.82
Collagen structure and stability. Annu Rev Biochem (2009) 4.62
Watching a protein as it functions with 150-ps time-resolved x-ray crystallography. Science (2003) 4.12
Bright ideas for chemical biology. ACS Chem Biol (2008) 3.84
Identification of transcribed sequences in Arabidopsis thaliana by using high-resolution genome tiling arrays. Proc Natl Acad Sci U S A (2005) 3.21
Defining the sequence-recognition profile of DNA-binding molecules. Proc Natl Acad Sci U S A (2006) 2.97
Dynamics of proteins in crystals: comparison of experiment with simple models. Biophys J (2002) 2.71
Hydrolytic stability of hydrazones and oximes. Angew Chem Int Ed Engl (2008) 2.45
Collagen stability: insights from NMR spectroscopic and hybrid density functional computational investigations of the effect of electronegative substituents on prolyl ring conformations. J Am Chem Soc (2002) 2.19
Project management system for structural and functional proteomics: Sesame. J Struct Funct Genomics (2003) 2.19
Ensemble refinement of protein crystal structures: validation and application. Structure (2007) 2.16
Pathway for polyarginine entry into mammalian cells. Biochemistry (2004) 2.14
Protein structural variation in computational models and crystallographic data. Structure (2007) 2.13
An electronic effect on protein structure. Protein Sci (2003) 2.04
Protocols for production of selenomethionine-labeled proteins in 2-L polyethylene terephthalate bottles using auto-induction medium. Protein Expr Purif (2005) 2.02
n-->pi* interactions in proteins. Nat Chem Biol (2010) 2.02
Prolyl 4-hydroxylase. Crit Rev Biochem Mol Biol (2010) 1.99
Nature of amide carbonyl--carbonyl interactions in proteins. J Am Chem Soc (2009) 1.89
Chemical synthesis of proteins. Annu Rev Biophys Biomol Struct (2005) 1.71
Insights on the conformational stability of collagen. Nat Prod Rep (2002) 1.71
Auto-induction medium for the production of [U-15N]- and [U-13C, U-15N]-labeled proteins for NMR screening and structure determination. Protein Expr Purif (2005) 1.65
High-throughput purification and quality assurance of Arabidopsis thaliana proteins for eukaryotic structural genomics. J Struct Funct Genomics (2005) 1.65
Simple chemical transformation of lignocellulosic biomass into furans for fuels and chemicals. J Am Chem Soc (2009) 1.63
Optimization and evaluation of a coarse-grained model of protein motion using x-ray crystal data. Biophys J (2006) 1.62
Self-assembly of synthetic collagen triple helices. Proc Natl Acad Sci U S A (2006) 1.61
Advances in Bioconjugation. Curr Org Chem (2010) 1.60
Structure and mechanism of mouse cysteine dioxygenase. Proc Natl Acad Sci U S A (2006) 1.59
Fermentable sugars by chemical hydrolysis of biomass. Proc Natl Acad Sci U S A (2010) 1.57
Stereoelectronic effects on polyproline conformation. Protein Sci (2006) 1.57
Stereoelectronic and steric effects in the collagen triple helix: toward a code for strand association. J Am Chem Soc (2005) 1.56
Ribonuclease inhibitor: structure and function. Prog Nucleic Acid Res Mol Biol (2005) 1.55
Translocation of a beta-peptide across cell membranes. J Am Chem Soc (2002) 1.55
Fluorogenic label for biomolecular imaging. ACS Chem Biol (2006) 1.54
Stereoelectronic effects on collagen stability: the dichotomy of 4-fluoroproline diastereomers. J Am Chem Soc (2003) 1.53
Structures and analysis of highly homologous psychrophilic, mesophilic, and thermophilic adenylate kinases. J Biol Chem (2004) 1.52
Reaction mechanism and kinetics of the traceless Staudinger ligation. J Am Chem Soc (2006) 1.52
Energetics of an n --> pi interaction that impacts protein structure. Org Lett (2006) 1.50
Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles. Sci Transl Med (2014) 1.50
Structural consequences of effector protein complex formation in a diiron hydroxylase. Proc Natl Acad Sci U S A (2008) 1.47
Ribonuclease inhibitor as an intracellular sentry. Nucleic Acids Res (2003) 1.45
Bright building blocks for chemical biology. ACS Chem Biol (2014) 1.44
Real-time footprinting of DNA in the first kinetically significant intermediate in open complex formation by Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A (2007) 1.44
Structural basis for selective activation of ABA receptors. Nat Struct Mol Biol (2010) 1.43
Probing substates in sperm whale myoglobin using high-pressure crystallography. Structure (2002) 1.43
Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. J Mol Biol (2007) 1.41
n --> pi* Interaction and n)(pi Pauli repulsion are antagonistic for protein stability. J Am Chem Soc (2010) 1.37
Creating protein models from electron-density maps using particle-filtering methods. Bioinformatics (2007) 1.37
Understanding protein flexibility through dimensionality reduction. J Comput Biol (2003) 1.36
Site-specific protein immobilization by Staudinger ligation. J Am Chem Soc (2003) 1.35
Sampling of the native conformational ensemble of myoglobin via structures in different crystalline environments. Proteins (2008) 1.34
A probabilistic approach to protein backbone tracing in electron density maps. Bioinformatics (2006) 1.34
Crystal structure of a functional dimer of the PhoQ sensor domain. J Biol Chem (2008) 1.32
Inductive Effects on the Energetics of Prolyl Peptide Bond Isomerization: Implications for Collagen Folding and Stability. J Am Chem Soc (1996) 1.32
Ribonucleases as novel chemotherapeutics : the ranpirnase example. BioDrugs (2008) 1.31
Application of elastic network models to proteins in the crystalline state. Biophys J (2009) 1.30
Restructuring the crystalline cellulose hydrogen bond network enhances its depolymerization rate. J Am Chem Soc (2011) 1.30
Peptide bond isosteres: ester or (E)-alkene in the backbone of the collagen triple helix. Org Lett (2005) 1.29
Semisynthesis and characterization of mammalian thioredoxin reductase. Biochemistry (2006) 1.28
Automatic domain decomposition of proteins by a Gaussian Network Model. Proteins (2004) 1.27
Bovine pancreatic ribonuclease: fifty years of the first enzymatic reaction mechanism. Biochemistry (2011) 1.27
Comparison of cell-based and cell-free protocols for producing target proteins from the Arabidopsis thaliana genome for structural studies. Proteins (2005) 1.26
Signature of n→π* interactions in α-helices. Protein Sci (2011) 1.25
Arginine grafting to endow cell permeability. ACS Chem Biol (2007) 1.24
Polyarginine as a multifunctional fusion tag. Protein Sci (2005) 1.24
Structure of the oxygen sensor in Bacillus subtilis: signal transduction of chemotaxis by control of symmetry. Structure (2003) 1.23
Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity. Curr Pharm Biotechnol (2008) 1.23
Tuning the pK(a) of fluorescein to optimize binding assays. Anal Chem (2007) 1.22
An evaluation of peptide-bond isosteres. Chembiochem (2011) 1.22
Olefin metathesis for chemical biology. Curr Opin Chem Biol (2008) 1.21
Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn. J Am Chem Soc (2002) 1.20
Bis-methionyl coordination in the crystal structure of the heme-binding domain of the streptococcal cell surface protein Shp. J Mol Biol (2007) 1.20
Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin. Acta Crystallogr D Biol Crystallogr (2006) 1.20
Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation. J Biol Chem (2013) 1.20
Effect of 3-hydroxyproline residues on collagen stability. J Am Chem Soc (2003) 1.19
Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway. J Cell Sci (2003) 1.18
Reciprocity of steric and stereoelectronic effects in the collagen triple helix. J Am Chem Soc (2006) 1.17
Stereoelectronic and steric effects in side chains preorganize a protein main chain. Proc Natl Acad Sci U S A (2009) 1.17
Roles of static and dynamic domains in stability and catalysis of adenylate kinase. Proc Natl Acad Sci U S A (2006) 1.17
Identifying latent enzyme activities: substrate ambiguity within modern bacterial sugar kinases. Biochemistry (2004) 1.17
Latent fluorophore based on the trimethyl lock. J Am Chem Soc (2005) 1.16
Bis-methionine ligation to heme iron in the streptococcal cell surface protein Shp facilitates rapid hemin transfer to HtsA of the HtsABC transporter. J Biol Chem (2007) 1.16
Structure of an ETHE1-like protein from Arabidopsis thaliana. Acta Crystallogr D Biol Crystallogr (2006) 1.16
Protein assembly by orthogonal chemical ligation methods. J Am Chem Soc (2003) 1.14
Structure and interactions of the first three RNA recognition motifs of splicing factor prp24. J Mol Biol (2007) 1.14
Water-soluble phosphinothiols for traceless staudinger ligation and integration with expressed protein ligation. J Am Chem Soc (2007) 1.14
Staudinger ligation of alpha-azido acids retains stereochemistry. J Org Chem (2002) 1.13
4-chloroprolines: synthesis, conformational analysis, and effect on the collagen triple helix. Biopolymers (2008) 1.13
Solvent Effects on the Energetics of Prolyl Peptide Bond Isomerization. J Am Chem Soc (1992) 1.12
The structure of flavin-dependent tryptophan 7-halogenase RebH. Proteins (2008) 1.12
Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM. J Biol Chem (2008) 1.12