Published in Gene on January 01, 1987
Survey of amino-terminal proteolytic cleavage sites in mitochondrial precursor proteins: leader peptides cleaved by two matrix proteases share a three-amino acid motif. Proc Natl Acad Sci U S A (1989) 2.10
Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease. J Clin Invest (1990) 1.91
Human cytochrome c oxidase: structure, function, and deficiency. J Bioenerg Biomembr (1997) 1.13
Both nuclear and mitochondrial cytochrome c oxidase mRNA levels increase dramatically during mouse postnatal development. Biochem J (1995) 1.01
Nucleotide sequence of cDNA encoding subunit IV of cytochrome c oxidase from fetal rat liver. Nucleic Acids Res (1989) 0.91
Serum-deprivation stimulates cap-binding by PARN at the expense of eIF4E, consistent with the observed decrease in mRNA stability. Nucleic Acids Res (2005) 0.90
Nucleotide sequence of cDNA for rat brain and liver cytochrome c oxidase subunit IV. Nucleic Acids Res (1989) 0.90
Cytochrome oxidase subunit V gene of Neurospora crassa: DNA sequences, chromosomal mapping, and evidence that the cya-4 locus specifies the structural gene for subunit V. Mol Cell Biol (1989) 0.89
The rat cytochrome c oxidase subunit IV gene family: tissue-specific and hormonal differences in subunit IV and cytochrome c mRNA expression. Nucleic Acids Res (1990) 0.86
Co-ordinate expression of cytochrome c oxidase subunit III and VIc mRNAs in rat tissues. Biochem J (1990) 0.85
A role for phosphodiesterase 3B in acquisition of brown fat characteristics by white adipose tissue in male mice. Endocrinology (2013) 0.85
The cyclope gene of Drosophila encodes a cytochrome c oxidase subunit VIc homolog. Genetics (2001) 0.82
Rapid evolution of the human gene for cytochrome c oxidase subunit IV. Proc Natl Acad Sci U S A (1992) 0.80
Nucleotide sequence of a mouse cDNA for subunit IV of cytochrome c oxidase. Nucleic Acids Res (1990) 0.79
Fending off decay: a combinatorial approach in intact cells for identifying mRNA stability elements. RNA (2001) 0.79
Low Cytochrome Oxidase 1 Links Mitochondrial Dysfunction to Atherosclerosis in Mice and Pigs. PLoS One (2017) 0.75
Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc Natl Acad Sci U S A (1990) 9.98
Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc Natl Acad Sci U S A (1991) 7.15
Transcription of the beta-like globin genes and pseudogenes of the goat in a cell-free system. Nucleic Acids Res (1981) 6.63
The petite mutation in yeast. Loss of mitochondrial deoxyribonucleic acid during induction of petites with ethidium bromide. J Mol Biol (1970) 6.44
A role for glucagon-like peptide-1 in the central regulation of feeding. Nature (1996) 6.03
Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature (2000) 5.71
Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: a distinctive clinical syndrome. Ann Neurol (1984) 5.21
Mitochondrial DNA deletions in progressive external ophthalmoplegia and Kearns-Sayre syndrome. N Engl J Med (1989) 4.87
Deletions of mitochondrial DNA in Kearns-Sayre syndrome. Neurology (1988) 4.28
Electrophoresis of DNA in agarose gels. Optimizing separations of conformational isomers of double- and single-stranded DNAs. Biochemistry (1977) 4.20
Dichloroacetate causes toxic neuropathy in MELAS: a randomized, controlled clinical trial. Neurology (2006) 4.11
Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity. Nat Med (1999) 3.88
Mitochondrial myopathies. Ann Neurol (1985) 3.81
Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli. J Bacteriol (1990) 3.78
Exercise intolerance due to mutations in the cytochrome b gene of mitochondrial DNA. N Engl J Med (1999) 3.76
An autosomal dominant disorder with multiple deletions of mitochondrial DNA starting at the D-loop region. Nature (1989) 3.75
Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease. Neurology (2010) 3.70
Duchenne muscular dystrophy: deficiency of dystrophin at the muscle cell surface. Cell (1988) 3.57
Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion. Science (1998) 3.39
Rapid purification of yeast mitochondrial DNA in high yield. Biochim Biophys Acta (1980) 3.23
Hypervariable regions in the putative glycoprotein of hepatitis C virus. Biochem Biophys Res Commun (1991) 3.09
A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA. Science (1989) 3.02
Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. Mol Cell Biol (1992) 2.83
Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis. Nature (2002) 2.71
Inclusion body myositis and myopathies. Ann Neurol (1995) 2.68
Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis. Nat Med (2001) 2.66
Action of cytochalasin D on cells of established lines. I. Early events. J Cell Biol (1974) 2.64
Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly gene. Nat Genet (1999) 2.59
Brain ischemia and reperfusion: molecular mechanisms of neuronal injury. J Neurol Sci (2000) 2.56
Molecular cloning of hepatitis C virus genome from a single Japanese carrier: sequence variation within the same individual and among infected individuals. Virus Res (1992) 2.56
Mitochondrial DNA mutations and pathogenesis. J Bioenerg Biomembr (1997) 2.54
mtDNA depletion with variable tissue expression: a novel genetic abnormality in mitochondrial diseases. Am J Hum Genet (1991) 2.53
Mitochondrial DNA in yeast and some mammalian species. Science (1966) 2.53
miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer (2010) 2.51
The genetics and pathology of oxidative phosphorylation. Nat Rev Genet (2001) 2.48
Recent life events, cortisol, dehydroepiandrosterone and the onset of major depression in high-risk adolescents. Br J Psychiatry (2000) 2.43
Evolution of nuclear- and mitochondrial-encoded subunit interaction in cytochrome c oxidase. Mol Biol Evol (2001) 2.36
Location and structure of the var1 gene on yeast mitochondrial DNA: nucleotide sequence of the 40.0 allele. Cell (1982) 2.34
Early pathological changes in the parkinsonian brain demonstrated by diffusion tensor MRI. J Neurol Neurosurg Psychiatry (2004) 2.32
Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy. Blood (2000) 2.31
Recombination via flanking direct repeats is a major cause of large-scale deletions of human mitochondrial DNA. Nucleic Acids Res (1990) 2.28
Isolation and partial characterisation of the relaxation protein from nuclei of cultured mouse and human cells. Eur J Biochem (1975) 2.27
HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Dev Biol (1999) 2.27
Molecular evolution of cytochrome c oxidase subunit I in primates: is there coevolution between mitochondrial and nuclear genomes? Mol Phylogenet Evol (2000) 2.26
The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. Br J Cancer (2011) 2.25
Endogenous steroids and financial risk taking on a London trading floor. Proc Natl Acad Sci U S A (2008) 2.22
Mitochondrial DNA mutations in human disease. Am J Med Genet (2001) 2.21
C-reactive protein and complement are important mediators of tissue damage in acute myocardial infarction. J Exp Med (1999) 2.17
Distribution of wild-type and common deletion forms of mtDNA in normal and respiration-deficient muscle fibers from patients with mitochondrial myopathy. Hum Mol Genet (1994) 2.16
Preferential synthesis of yeast mitochondrial DNA in the absence of protein synthesis. J Mol Biol (1969) 2.16
Melas: an original case and clinical criteria for diagnosis. Neuromuscul Disord (1992) 2.15
Cardiac involvement in mitochondrial diseases. A study on 17 patients with documented mitochondrial DNA defects. Circulation (1995) 2.15
Reevaluation of the thyroidal radioactive iodine uptake test, with special reference to reversible primary hypothyroidism with elevated thyroid radioiodine uptake. J Clin Endocrinol Metab (1988) 2.15
Lysosomal glycogen storage disease with normal acid maltase. Neurology (1981) 2.13
Diastolic paradoxic jet flow in patients with hypertrophic cardiomyopathy: evidence of concealed apical asynergy with cavity obliteration. J Am Coll Cardiol (1992) 2.12
Antibiotic resistant tuberculosis in the United Kingdom: 1993-1999. Thorax (2002) 2.12
Allogeneic stem cell transplantation corrects biochemical derangements in MNGIE. Neurology (2006) 2.11
Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy. Lancet (1991) 2.10
Psychoendocrine antecedents of persistent first-episode major depression in adolescents: a community-based longitudinal enquiry. Psychol Med (2003) 2.07
Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling. Proc Natl Acad Sci U S A (2000) 2.05
The presence of ribonucleotides in mature closed-circular mitochondrial DNA. Proc Natl Acad Sci U S A (1973) 2.05
WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood (1994) 2.03
Widespread tissue distribution of mitochondrial DNA deletions in Kearns-Sayre syndrome. Neurology (1990) 1.97
Fracture history and bone loss in patients with MS. Neurology (1998) 1.97
The mitochondrial tRNA(Leu(UUR)) mutation in mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes (MELAS): genetic, biochemical, and morphological correlations in skeletal muscle. Am J Hum Genet (1992) 1.94
Muscle carnitine palmityltransferase deficiency and myoglobinuria. Science (1973) 1.93
Lumping or splitting? "Ophthalmoplegia-plus" or Kearns-Sayre syndrome? Ann Neurol (1977) 1.90
Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: a CoQ10-responsive condition. Neurology (2005) 1.90
Detection of "deleted" mitochondrial genomes in cytochrome-c oxidase-deficient muscle fibers of a patient with Kearns-Sayre syndrome. Proc Natl Acad Sci U S A (1989) 1.88
Cerebral lactic acidosis correlates with neurological impairment in MELAS. Neurology (2004) 1.83
Mitochondrial neurogastrointestinal encephalomyopathy: an autosomal recessive disorder due to thymidine phosphorylase mutations. Ann Neurol (2000) 1.82
Benign infantile mitochondrial myopathy due to reversible cytochrome c oxidase deficiency. Ann Neurol (1983) 1.82
Prognostic value of tumor-associated macrophage count in human bladder cancer. Int J Urol (2000) 1.81
Coenzyme Q deficiency and cerebellar ataxia associated with an aprataxin mutation. Neurology (2005) 1.80
Phylogenetic subgroups of human T cell lymphotropic virus (HTLV) type I in the tax gene and their association with different risks for HTLV-I-associated myelopathy/tropical spastic paraparesis. J Infect Dis (2000) 1.80
Immunologic responses in malnourished children. Am J Clin Nutr (1975) 1.78
Transthyretin: a choroid plexus-specific transport protein in human brain. The 1986 S. Weir Mitchell award. Neurology (1986) 1.78
Rapid disease progression correlates with instability of mutant SOD1 in familial ALS. Neurology (2005) 1.78
Evidence that multiple residues on both the alpha-helices of the class I MHC molecule are simultaneously recognized by the T cell receptor. Cell (1988) 1.77
Familial cerebellar ataxia with muscle coenzyme Q10 deficiency. Neurology (2001) 1.75
Brain injury by global ischemia and reperfusion: a theoretical perspective on membrane damage and repair. Neurology (1993) 1.74
Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. Br J Cancer (2011) 1.74
Action of cytochalasin D on cells of established lines. II. Cortex and microfilaments. J Cell Biol (1974) 1.74
Cerebellar ataxia and coenzyme Q10 deficiency. Neurology (2003) 1.73
Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance. Cancer Res (1994) 1.73
Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-catenin. J Biol Chem (1999) 1.72
Atrophic rhinitis produced by intranasal inoculation of Bordetella bronchiseptica in hysterectomy produced colostrum-deprived pigs. Cornell Vet (1971) 1.71
GFAP mutations, age at onset, and clinical subtypes in Alexander disease. Neurology (2011) 1.69