Published in EMBO J on December 20, 1988
Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA. EMBO J (1989) 4.69
Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains. EMBO J (1993) 3.51
Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit. Proc Natl Acad Sci U S A (1992) 2.82
Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing. Proc Natl Acad Sci U S A (1992) 2.66
Mutations in the yeast RNA14 and RNA15 genes result in an abnormal mRNA decay rate; sequence analysis reveals an RNA-binding domain in the RNA15 protein. Mol Cell Biol (1991) 2.35
Recognition of U1 and U2 small nuclear RNAs can be altered by a 5-amino-acid segment in the U2 small nuclear ribonucleoprotein particle (snRNP) B" protein and through interactions with U2 snRNP-A' protein. Mol Cell Biol (1991) 2.33
Genes encoding glycine-rich Arabidopsis thaliana proteins with RNA-binding motifs are influenced by cold treatment and an endogenous circadian rhythm. Plant Physiol (1994) 2.29
Direct, sequence-specific binding of the human U1-70K ribonucleoprotein antigen protein to loop I of U1 small nuclear RNA. Mol Cell Biol (1989) 2.29
Cloning of a yeast U1 snRNP 70K protein homologue: functional conservation of an RNA-binding domain between humans and yeast. EMBO J (1991) 1.97
Structure and expression of the Drosophila melanogaster gene for the U1 small nuclear ribonucleoprotein particle 70K protein. Mol Cell Biol (1990) 1.85
Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3. Genetics (1996) 1.76
The Drosophila suppressor of sable gene encodes a polypeptide with regions similar to those of RNA-binding proteins. Mol Cell Biol (1991) 1.71
A specific 31-nucleotide domain of U1 RNA directly interacts with the 70K small nuclear ribonucleoprotein component. Mol Cell Biol (1989) 1.68
Polar zippers: their role in human disease. Protein Sci (1994) 1.53
A conserved epitope on a subset of SR proteins defines a larger family of Pre-mRNA splicing factors. J Cell Biol (1995) 1.51
The EBNA-2 arginine-glycine domain is critical but not essential for B-lymphocyte growth transformation; the rest of region 3 lacks essential interactive domains. J Virol (1994) 1.27
Structure and expression of a plant U1 snRNP 70K gene: alternative splicing of U1 snRNP 70K pre-mRNAs produces two different transcripts. Plant Cell (1996) 1.23
The yeast homolog of the U1 snRNP protein 70K is encoded by the SNP1 gene. Nucleic Acids Res (1992) 1.22
The amino-terminal domain of yeast U1-70K is necessary and sufficient for function. Mol Cell Biol (1995) 1.02
Splicing factor SF1 from Drosophila and Caenorhabditis: presence of an N-terminal RS domain and requirement for viability. RNA (1999) 1.02
Degradation of a developmentally regulated mRNA in Xenopus embryos is controlled by the 3' region and requires the translation of another maternal mRNA. Mol Cell Biol (1991) 0.88
Tobacco nuclear gene for the 31 kd chloroplast ribonucleoprotein: genomic organization, sequence analysis and expression. Nucleic Acids Res (1991) 0.87
Key residues revealed in a major conformational epitope of the U1-70K protein. Proc Natl Acad Sci U S A (1999) 0.82
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1990) 0.75
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res (1984) 181.98
Genomic sequencing. Proc Natl Acad Sci U S A (1984) 92.36
New M13 vectors for cloning. Methods Enzymol (1983) 90.74
A simple and very efficient method for generating cDNA libraries. Gene (1983) 55.36
Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res (1984) 39.52
A catalogue of splice junction sequences. Nucleic Acids Res (1982) 39.41
pEMBL: a new family of single stranded plasmids. Nucleic Acids Res (1983) 19.19
Dideoxy sequencing method using denatured plasmid templates. Anal Biochem (1986) 17.34
Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A (1979) 14.61
A compensatory base change in U1 snRNA suppresses a 5' splice site mutation. Cell (1986) 9.65
The U1 small nuclear RNA-protein complex selectively binds a 5' splice site in vitro. Cell (1983) 9.00
The 5' terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors. Cell (1984) 6.25
"Nonrandom" DNA sequence analysis in bacteriophage M13 by the dideoxy chain-termination method. Proc Natl Acad Sci U S A (1982) 5.90
Cloning of the human cDNA for the U1 RNA-associated 70K protein. EMBO J (1986) 4.43
Xenopus 5S gene transcription factor, TFIIIA: characterization of a cDNA clone and measurement of RNA levels throughout development. Cell (1984) 4.32
Primary structure of human nuclear ribonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-rRNA-binding proteins. Mol Cell Biol (1987) 3.91
Isolation of small nuclear ribonucleoproteins containing U1, U2, U4, U5, and U6 RNAs. J Biol Chem (1983) 3.65
cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins. EMBO J (1987) 3.47
Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes. EMBO J (1983) 2.81
Analysis of a cDNA clone expressing a human autoimmune antigen: full-length sequence of the U2 small nuclear RNA-associated B" antigen. Proc Natl Acad Sci U S A (1987) 2.75
Formation of the 3' end of U1 snRNA is directed by a conserved sequence located downstream of the coding region. EMBO J (1985) 2.69
A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen. Cell (1987) 2.58
Sequences required for 3' end formation of human U2 small nuclear RNA. Cell (1985) 2.57
The human U1-70K snRNP protein: cDNA cloning, chromosomal localization, expression, alternative splicing and RNA-binding. Nucleic Acids Res (1987) 2.57
Control of ribosomal protein gene expression. Biochim Biophys Acta (1988) 2.50
Structure and expression of the human haptoglobin locus. EMBO J (1985) 2.09
Molecular cloning of a cDNA encoding the human Sm-D autoantigen. Proc Natl Acad Sci U S A (1988) 2.08
Expression of two Xenopus laevis ribosomal protein genes in injected frog oocytes. A specific splicing block interferes with the L1 RNA maturation. J Mol Biol (1984) 2.03
Expression of ribosomal-protein genes in Xenopus laevis development. Cell (1982) 1.96
Structure of the mouse nucleolin gene. The complete sequence reveals that each RNA binding domain is encoded by two independent exons. J Mol Biol (1988) 1.76
cDNA cloning of a human autoimmune nuclear ribonucleoprotein antigen. Proc Natl Acad Sci U S A (1985) 1.59
Small nuclear U-ribonucleoproteins in Xenopus laevis development. Uncoupled accumulation of the protein and RNA components. J Mol Biol (1984) 1.56
Formation of the 3' end on U snRNAs requires at least three sequence elements. EMBO J (1986) 1.52
Ribonucleoprotein particles in cellular processes. J Cell Biol (1988) 1.44
Isolation and characterization of a complementary DNA expressing human U1 small nuclear ribonucleoprotein C polypeptide. J Immunol (1988) 1.37
Coordinate expression of ribosomal protein genes during Xenopus development. Dev Biol (1985) 1.19
CRM1 is an export receptor for leucine-rich nuclear export signals. Cell (1997) 18.60
Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA. Science (1971) 10.54
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell (1995) 9.98
Nucleocytoplasmic transport. Science (1996) 8.76
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity (1999) 7.78
HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc Natl Acad Sci U S A (1997) 6.92
Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice. Science (1996) 6.70
Complete sequence of the staphylococcal gene encoding protein A. A gene evolved through multiple duplications. J Biol Chem (1984) 5.94
Genes specifically expressed at growth arrest of mammalian cells. Cell (1988) 5.61
Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding. Cell (1986) 5.59
Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell (2001) 5.33
Translation of MuLV and MSV RNAs in nuclease-treated reticulocyte extracts: enhancement of the gag-pol polypeptide with yeast suppressor tRNA. Cell (1978) 5.31
The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J (1997) 5.08
Nuclear export of different classes of RNA is mediated by specific factors. J Cell Biol (1994) 4.99
Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins. Cell (1985) 4.98
Monomethylated cap structures facilitate RNA export from the nucleus. Cell (1990) 4.72
Virus-receptor interaction in an adenovirus system. J Virol (1968) 4.69
Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA. EMBO J (1989) 4.69
A novel method for site-directed mutagenesis: its application to an eukaryotic tRNAPro gene promoter. EMBO J (1982) 4.67
Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B'' and their cognate RNAs. Nature (1990) 4.67
A nuclear cap binding protein complex involved in pre-mRNA splicing. Cell (1994) 4.56
Addition of polyadenylate sequences to virus-specific RNA during adenovirus replication. Proc Natl Acad Sci U S A (1971) 4.48
Cloning of the human cDNA for the U1 RNA-associated 70K protein. EMBO J (1986) 4.43
Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity (1997) 4.19
A general method to select for M13 clones carrying base pair substitution mutants constructed in vitro. Nucleic Acids Res (1983) 4.14
Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex. EMBO J (1997) 4.06
A cap-binding protein complex mediating U snRNA export. Nature (1995) 3.89
Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature (1999) 3.84
Isolation and characterization of adenovirus messenger ribonucleic acid in productive infection. J Virol (1972) 3.83
An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes. Nature (1985) 3.80
Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences. Science (1995) 3.79
Early events of virus-cell interaction in an adenovirus system. J Virol (1969) 3.68
Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. Nat Cell Biol (2001) 3.67
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion. EMBO J (1994) 3.60
Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs. EMBO J (1987) 3.50
Identification of a nuclear export receptor for tRNA. Curr Biol (1998) 3.49
U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. Mol Cell (1998) 3.39
Structural proteins of adenoviruses. X. Isolation and topography of low molecular weight antigens from the virion of adenovirus type 2. Virology (1973) 3.26
The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal. Cell (1990) 3.24
Unrelated animal viruses share receptors. Nature (1976) 3.24
Interleukin 6 is required for the development of collagen-induced arthritis. J Exp Med (1998) 3.20
In vitro assembly of U1 snRNPs. EMBO J (1987) 3.18
CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. Genes Dev (1994) 3.12
Specific alterations of coxsackievirus B3 eluted from HeLa cells. J Virol (1971) 3.10
RNA export. Cell (1995) 3.03
Nucleocytoplasmic transport: the last 200 nanometers. Cell (1998) 3.00
A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2. Cell (1976) 3.00
Cell-specific expression of a transfected human alpha 1-antitrypsin gene. Cell (1985) 2.99
Gene for staphylococcal protein A. Proc Natl Acad Sci U S A (1983) 2.97
Common and interchangeable elements in the promoters of genes transcribed by RNA polymerase iii. Cell (1983) 2.94
Promoter of a eukaryotic tRNAPro gene is composed of three noncontiguous regions. Proc Natl Acad Sci U S A (1982) 2.91
Hydroxyapatite chromatography and formamide denaturation of adenovirus DNA. J Virol (1973) 2.90
PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation. Cell (2000) 2.88
A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export. J Cell Biol (1996) 2.84
Transformation reveals a chromosomal locus of the gene(s) for methicillin resistance in Staphylococcus aureus. J Bacteriol (1975) 2.83
RNA synthesis and processing in adenovirus-infected cells. Cold Spring Harb Symp Quant Biol (1975) 2.82
Xenopus laevis U2 snRNA genes: tandemly repeated transcription units sharing 5' and 3' flanking homology with other RNA polymerase II transcribed genes. EMBO J (1983) 2.81
CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy. J Clin Invest (1998) 2.74
A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export. J Cell Biol (1997) 2.74
Processing of adenovirus specific nuclear RNA during virus replication. Virology (1972) 2.71
Inhibition of influenza virus ribonucleic acid polymerase by ribavirin triphosphate. Antimicrob Agents Chemother (1977) 2.71
Cis- and trans-acting elements responsible for the cell-specific expression of the human alpha 1-antitrypsin gene. EMBO J (1987) 2.69
An improved positive selection plasmid vector constructed by oligonucleotide mediated mutagenesis. Nucleic Acids Res (1983) 2.69
Cell proliferation inhibited by MyoD1 independently of myogenic differentiation. Nature (1990) 2.68
Elevated levels of interleukin-6 in unstable angina. Circulation (1996) 2.66
Structural proteins of adenoviruses. IV. Sequential degradation of the adenovirus type 2 virion. Virology (1970) 2.65
Importin provides a link between nuclear protein import and U snRNA export. Cell (1996) 2.65
Transcription by RNA polymerase III. Curr Top Dev Biol (1983) 2.63
Further evidence on the nuclear origin and transfer to the cytoplasm of polyadenylic acid sequences in mammalian cell RNA. J Mol Biol (1973) 2.61
Structure of the human alpha 1-acid glycoprotein gene: sequence homology with other human acute phase protein genes. Nucleic Acids Res (1985) 2.59
Hybridization maps of early and late messenger RNA sequences on the adenovirus type 2 genome. J Mol Biol (1976) 2.58
The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA. Cell (1993) 2.58
The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein. Nat Struct Biol (2000) 2.53
Isolation and characterization of multiple human genes homologous to the oncogenes of avian erythroblastosis virus. EMBO J (1983) 2.52
Nucleocytoplasmic transport: Ran, beta and beyond. Trends Cell Biol (2001) 2.50
A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5' splice site. Genes Dev (1996) 2.50
A transcription factor which binds to the enhancers of SV40, immunoglobulin heavy chain and U2 snRNA genes. Nature (1987) 2.48
Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motif. Cell (1994) 2.45
Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport. J Cell Biol (1991) 2.45
Early interaction between animal viruses and cells. Monogr Virol (1974) 2.43
Transfection of Staphylococcus aureus with bacteriophage deoxyribonucleic acid. J Bacteriol (1972) 2.42
Recombinant interleukin 6 regulates the transcriptional activation of a set of human acute phase genes. J Biol Chem (1988) 2.40
The role of exportin-t in selective nuclear export of mature tRNAs. EMBO J (1998) 2.40
RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase. Mol Cell Biol (1999) 2.37
Regulation of G1 progression by E2A and Id helix-loop-helix proteins. EMBO J (1994) 2.33
The release of growth arrest by microinjection of adenovirus E1A DNA. EMBO J (1985) 2.32
Protein A mutants of Staphylococcus aureus. J Bacteriol (1971) 2.32
Participation of the nuclear cap binding complex in pre-mRNA 3' processing. Proc Natl Acad Sci U S A (1997) 2.31
The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing. Genes Dev (2000) 2.27
Intermediates in adenovirus assembly. J Virol (1976) 2.26
Structural proteins of adenoviruses. I. Purification and characterization of the adenovirus type 2 hexon antigen. Virology (1967) 2.25
Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice. Hepatology (2000) 2.24
Functional analysis of mutant Xenopus U2 snRNAs. Cell (1989) 2.23
GTP hydrolysis by Ran is required for nuclear envelope assembly. Mol Cell (2000) 2.22
Factors affecting competence for transformation in Staphylococcus aureus. J Bacteriol (1974) 2.22
A cap binding protein that may mediate nuclear export of RNA polymerase II-transcribed RNAs. J Cell Biol (1992) 2.20
Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway. EMBO J (2001) 2.17
Competence for transfection in Staphylococcus aureus. J Bacteriol (1973) 2.16
The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteins. EMBO J (2001) 2.14
Relationship between the two components of the split promoter of eukaryotic tRNA genes. Proc Natl Acad Sci U S A (1982) 2.13