Published in Sci Transl Med on April 02, 2014
T follicular helper cell differentiation, function, and roles in disease. Immunity (2014) 3.29
Pathophysiology of T follicular helper cells in humans and mice. Nat Immunol (2015) 1.80
Local triggering of the ICOS coreceptor by CD11c(+) myeloid cells drives organ inflammation in lupus. Immunity (2015) 1.58
Bcl-2 as a Therapeutic Target in Human Tubulointerstitial Inflammation. Arthritis Rheumatol (2016) 1.41
OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response. Immunity (2015) 1.17
Germinal centers and autoimmune disease in humans and mice. Immunol Cell Biol (2016) 1.08
New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndrome. Curr Opin Rheumatol (2015) 0.86
B Cells, Antibodies, and More. Clin J Am Soc Nephrol (2015) 0.85
Anti-CD28 Antibody and Belatacept Exert Differential Effects on Mechanisms of Renal Allograft Rejection. J Am Soc Nephrol (2016) 0.84
Tracing Donor-MHC Class II Reactive B cells in Mouse Cardiac Transplantation: Delayed CTLA4-Ig Treatment Prevents Memory Alloreactive B-Cell Generation. Transplantation (2016) 0.83
T cells and autoimmune kidney disease. Nat Rev Nephrol (2017) 0.80
Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus. Lupus Sci Med (2016) 0.79
Editorial: autoimmunity to vimentin and lupus nephritis. Arthritis Rheumatol (2014) 0.79
The Lupus Susceptibility Gene Pbx1 Regulates the Balance between Follicular Helper T Cell and Regulatory T Cell Differentiation. J Immunol (2016) 0.78
Genetics of Lupus Nephritis: Clinical Implications. Semin Nephrol (2015) 0.78
T cells in Systemic Lupus Erythematosus. Curr Opin Immunol (2016) 0.78
Transplantation: molecular phenotyping of T-cell-mediated rejection. Nat Rev Nephrol (2014) 0.76
Bob1 limits cellular frequency of T-follicular helper cells. Eur J Immunol (2016) 0.76
The BAFFling effects of rituximab in lupus: danger ahead? Nat Rev Rheumatol (2016) 0.76
Loss of Immune Tolerance Is Controlled by ICOS in Sle1 Mice. J Immunol (2016) 0.75
Disruption of Pathogenic Cellular Networks by IL-21 Blockade Leads to Disease Amelioration in Murine Lupus. J Immunol (2017) 0.75
B Cell Immunity in Solid Organ Transplantation. Front Immunol (2017) 0.75
Metabolic Factors that Contribute to Lupus Pathogenesis. Crit Rev Immunol (2016) 0.75
T follicular helper cells in the generation of alloantibody and graft rejection. Curr Opin Organ Transplant (2016) 0.75
Overview of pathophysiology and treatment of human lupus nephritis. Curr Opin Rheumatol (2016) 0.75
BAFF Induces Tertiary Lymphoid Structures and Positions T Cells within the Glomeruli during Lupus Nephritis. J Immunol (2017) 0.75
Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity. J Immunol (2017) 0.75
Extrafollicular CD4(+) T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease. Nat Commun (2017) 0.75
May you live in interesting times: Challenges and opportunities in Lupus research. Arthritis Rheumatol (2017) 0.75
Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications. Transl Res (2017) 0.75
The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum (1982) 67.54
Three-dimensional segregation of supramolecular activation clusters in T cells. Nature (1998) 14.14
Follicular helper CD4 T cells (TFH). Annu Rev Immunol (2011) 12.50
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity (2008) 9.61
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity (2009) 7.69
Germinal centers. Annu Rev Immunol (2012) 6.26
Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. Immunity (2011) 5.98
Germinal-center organization and cellular dynamics. Immunity (2007) 5.62
SAP-controlled T-B cell interactions underlie germinal centre formation. Nature (2008) 5.14
A validated regulatory network for Th17 cell specification. Cell (2012) 4.82
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J Exp Med (2010) 4.04
In vivo imaging of germinal centres reveals a dynamic open structure. Nature (2007) 3.83
Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum (2010) 3.76
A receptor/cytoskeletal movement triggered by costimulation during T cell activation. Science (1998) 3.76
Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12. Immunol Cell Biol (2009) 3.51
Activation of autoreactive B cells by CpG dsDNA. Immunity (2003) 3.40
Banff '09 meeting report: antibody mediated graft deterioration and implementation of Banff working groups. Am J Transplant (2010) 3.29
Identification of human B and T lymphocytes by scanning electron microscopy. J Exp Med (1973) 3.21
IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J Exp Med (2009) 3.18
Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone. Immunity (2011) 2.81
Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels. Proc Natl Acad Sci U S A (1998) 2.69
A fuzzy c-means (FCM)-based approach for computerized segmentation of breast lesions in dynamic contrast-enhanced MR images. Acad Radiol (2006) 2.47
Prognostic factors in lupus nephritis. Contribution of renal histologic data. Am J Med (1983) 2.38
Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. J Immunol (2012) 2.34
The good, the bad and the ugly - TFH cells in human health and disease. Nat Rev Immunol (2013) 2.33
Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat Immunol (2012) 2.26
The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation. Curr Biol (2006) 2.20
The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development. Immunity (2012) 2.19
Deconvolution microscopy. Adv Biochem Eng Biotechnol (2005) 2.16
Tuning immune responses: diversity and adaptation of the immunological synapse. Nat Rev Immunol (2005) 1.98
Anniversary paper: History and status of CAD and quantitative image analysis: the role of Medical Physics and AAPM. Med Phys (2008) 1.86
Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation. J Immunol (2011) 1.84
Understanding the structure and function of the immunological synapse. Cold Spring Harb Perspect Biol (2010) 1.54
Predicting outcomes of lupus nephritis with tubulointerstitial inflammation and scarring. Arthritis Care Res (Hoboken) (2011) 1.54
In situ B cell-mediated immune responses and tubulointerstitial inflammation in human lupus nephritis. J Immunol (2010) 1.54
In vitro detection of C4d-fixing HLA alloantibodies: associations with capillary C4d deposition in kidney allografts. Am J Transplant (2007) 1.52
Antigen-dependent and -independent Ca2+ responses triggered in T cells by dendritic cells compared with B cells. J Exp Med (1998) 1.46
Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus. Immunity (2013) 1.40
Kinetics and expression patterns of chemokine receptors in human CD4+ T lymphocytes primed by myeloid or plasmacytoid dendritic cells. Eur J Immunol (2003) 1.29
The regulation of actin remodeling during T-cell-APC conjugate formation. Immunol Rev (2002) 1.24
The clinical and renal biopsy predictors of long-term outcome in lupus nephritis: a study of 87 patients and review of the literature. Q J Med (1989) 1.20
A dual-stage method for lesion segmentation on digital mammograms. Med Phys (2007) 1.17
IL-17-producing T cells in lupus nephritis. Lupus (2011) 1.15
T cell-independent spontaneous loss of tolerance by anti-double-stranded DNA B cells in C57BL/6 mice. J Immunol (2008) 1.04
Germinal center B-cells. Autoimmunity (2012) 0.89
Calcium responses elicited in human T cells and dendritic cells by cell-cell interaction and soluble ligands. Int Immunol (1999) 0.87
Capillary C4d deposition as a marker of humoral immunity in renal allograft rejection. J Am Soc Nephrol (2002) 0.83
Visualization of Cell-Cell Interaction Contacts: Synapses and Kinapses. Self Nonself (2011) 0.78
HMGB1 and RAGE in inflammation and cancer. Annu Rev Immunol (2010) 5.65
Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial. Arthritis Rheum (2010) 4.57
Bile cast nephropathy is a common pathologic finding for kidney injury associated with severe liver dysfunction. Kidney Int (2013) 4.36
A fuzzy c-means (FCM)-based approach for computerized segmentation of breast lesions in dynamic contrast-enhanced MR images. Acad Radiol (2006) 2.47
Volumetric texture analysis of breast lesions on contrast-enhanced magnetic resonance images. Magn Reson Med (2007) 2.31
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse. Immunity (2006) 2.23
Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes. Kidney Int (2010) 2.18
Fractal analysis of mammographic parenchymal patterns in breast cancer risk assessment. Acad Radiol (2007) 2.16
Computerized interpretation of breast MRI: investigation of enhancement-variance dynamics. Med Phys (2004) 2.14
Transforming growth factor-beta-dependent and -independent pathways of induction of tubulointerstitial fibrosis in beta6(-/-) mice. Am J Pathol (2003) 2.05
Automatic identification and classification of characteristic kinetic curves of breast lesions on DCE-MRI. Med Phys (2006) 1.94
In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes. Am J Physiol Endocrinol Metab (2009) 1.88
A study on several machine-learning methods for classification of malignant and benign clustered microcalcifications. IEEE Trans Med Imaging (2005) 1.87
B cell antigen receptor signaling and internalization are mutually exclusive events. PLoS Biol (2006) 1.85
Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus. Arthritis Rheum (2011) 1.79
Prostate cancer: differentiation of central gland cancer from benign prostatic hyperplasia by using diffusion-weighted and dynamic contrast-enhanced MR imaging. Radiology (2010) 1.70
Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients. Arthritis Rheum (2010) 1.67
Lung cancer: performance of automated lung nodule detection applied to cancers missed in a CT screening program. Radiology (2002) 1.66
Role of CXCL13 in cigarette smoke-induced lymphoid follicle formation and chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 1.63
Cancerous breast lesions on dynamic contrast-enhanced MR images: computerized characterization for image-based prognostic markers. Radiology (2010) 1.60
Kinesin motor proteins as targets for cancer therapy. Cancer Metastasis Rev (2009) 1.60
Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2. Nat Immunol (2011) 1.59
Computerized analysis of digitized mammograms of BRCA1 and BRCA2 gene mutation carriers. Radiology (2002) 1.58
Seminal vesicle invasion in prostate cancer: evaluation by using multiparametric endorectal MR imaging. Radiology (2013) 1.57
Computerized analysis of mammographic parenchymal patterns for assessing breast cancer risk: effect of ROI size and location. Med Phys (2004) 1.57
Computerized diagnosis of breast lesions on ultrasound. Med Phys (2002) 1.56
TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells. J Immunol (2007) 1.56
Predicting outcomes of lupus nephritis with tubulointerstitial inflammation and scarring. Arthritis Care Res (Hoboken) (2011) 1.54
In situ B cell-mediated immune responses and tubulointerstitial inflammation in human lupus nephritis. J Immunol (2010) 1.54
The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H-deficient mice. Kidney Int (2012) 1.52
A unique function for cyclin D3 in early B cell development. Nat Immunol (2006) 1.51
Potential effect of different radiologist reporting methods on studies showing benefit of CAD. Acad Radiol (2008) 1.51
Vitamin D receptor attenuates renal fibrosis by suppressing the renin-angiotensin system. J Am Soc Nephrol (2010) 1.50
Computerized texture analysis of mammographic parenchymal patterns of digitized mammograms. Acad Radiol (2005) 1.49
Quantitative imaging test approval and biomarker qualification: interrelated but distinct activities. Radiology (2011) 1.48
Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development. Nat Immunol (2009) 1.48
Histopathological predictors of renal function decrease after laparoscopic radical nephrectomy. J Urol (2010) 1.48
The plasma cell signature in autoimmune disease. Arthritis Rheumatol (2014) 1.47
Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus. Arthritis Res Ther (2010) 1.45
Single-molecule tracing on a fluidic microchip for quantitative detection of low-abundance nucleic acids. J Am Chem Soc (2005) 1.44
Diffusion-weighted MR imaging of focal liver lesions in the left and right lobes: is there a difference in ADC values? Acad Radiol (2013) 1.44
Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expression. Mol Cell Biol (2010) 1.42
Power spectral analysis of mammographic parenchymal patterns for breast cancer risk assessment. J Digit Imaging (2008) 1.41
Renal FcRn reclaims albumin but facilitates elimination of IgG. J Am Soc Nephrol (2009) 1.40
Revisiting the central gland anatomy via MRI: does the central gland extend below the level of verumontanum? J Magn Reson Imaging (2013) 1.39
One hundred useful references in pediatric cardiac intensive care: the 2012 update. Pediatr Crit Care Med (2013) 1.39
Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients. J Immunol (2011) 1.34
The tyrosine phosphatase PRL-1 localizes to the endoplasmic reticulum and the mitotic spindle and is required for normal mitosis. J Biol Chem (2002) 1.32
Breast cancer: effectiveness of computer-aided diagnosis observer study with independent database of mammograms. Radiology (2002) 1.29
Classification of breast lesions with multimodality computer-aided diagnosis: observer study results on an independent clinical data set. Radiology (2006) 1.29
Modified anti-CD3 therapy in psoriatic arthritis: a phase I/II clinical trial. J Rheumatol (2002) 1.28
Computerized detection and classification of cancer on breast ultrasound. Acad Radiol (2004) 1.22
The lupus family registry and repository. Rheumatology (Oxford) (2010) 1.21
The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways. Mol Cell Biol (2002) 1.20
Bruton's tyrosine kinase mediates NF-kappa B activation and B cell survival by B cell-activating factor receptor of the TNF-R family. J Immunol (2007) 1.19
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation. Nat Immunol (2012) 1.18
Evaluation of computer-aided diagnosis on a large clinical full-field digital mammographic dataset. Acad Radiol (2008) 1.17
A dual-stage method for lesion segmentation on digital mammograms. Med Phys (2007) 1.17
Coexpression of an intronic microRNA and its host gene reveals a potential role for miR-483-5p as an IGF2 partner. Mol Cell Endocrinol (2010) 1.16
Exploring nonlinear feature space dimension reduction and data representation in breast Cadx with Laplacian eigenmaps and t-SNE. Med Phys (2010) 1.16
Mouse podocyte complement factor H: the functional analog to human complement receptor 1. J Am Soc Nephrol (2007) 1.16
Evaluating imaging and computer-aided detection and diagnosis devices at the FDA. Acad Radiol (2012) 1.13
Dynamic Contrast-enhanced MR Imaging Curve-type Analysis: Is It Helpful in the Differentiation of Prostate Cancer from Healthy Peripheral Zone? Radiology (2015) 1.11
CAT-8015: a second-generation pseudomonas exotoxin A-based immunotherapy targeting CD22-expressing hematologic malignancies. Clin Cancer Res (2009) 1.10
Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptor. J Immunol (2007) 1.09
B-cell targeted therapeutics in clinical development. Arthritis Res Ther (2013) 1.09
Robustness of computerized lesion detection and classification scheme across different breast US platforms. Radiology (2005) 1.06
Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells. Proc Natl Acad Sci U S A (2009) 1.06
Potentiation of kinesin spindle protein inhibitor-induced cell death by modulation of mitochondrial and death receptor apoptotic pathways. Cancer Res (2007) 1.06
Chronic kidney disease induced in mice by reversible unilateral ureteral obstruction is dependent on genetic background. Am J Physiol Renal Physiol (2010) 1.06
Pauci-immune glomerulonephritis in children: a clinicopathologic study of 21 patients. Pediatr Nephrol (2015) 1.05
Promoter variant of PIK3C3 is associated with autoimmunity against Ro and Sm epitopes in African-American lupus patients. J Biomed Biotechnol (2010) 1.05
Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failure. J Am Soc Nephrol (2007) 1.05
Computerized lesion detection on breast ultrasound. Med Phys (2002) 1.05
Four-color flow cytometry shows strong concordance with bone marrow morphology and cytogenetics in the evaluation for myelodysplasia. Am J Clin Pathol (2005) 1.03
Targeted expression of human vitamin d receptor in the skin promotes the initiation of the postnatal hair follicle cycle and rescues the alopecia in vitamin D receptor null mice. J Invest Dermatol (2002) 1.03
Performance of computer-aided diagnosis in the interpretation of lesions on breast sonography. Acad Radiol (2004) 1.03
A spin-drying technique for lyopreservation of mammalian cells. Ann Biomed Eng (2011) 1.02
Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha. J Immunol (2002) 1.02
Relationships between computer-extracted mammographic texture pattern features and BRCA1/2 mutation status: a cross-sectional study. Breast Cancer Res (2014) 1.02
The autoimmune disease risk allele of UBE2L3 in African American patients with systemic lupus erythematosus: a recessive effect upon subphenotypes. J Rheumatol (2011) 1.01
Evaluation of clinical breast MR imaging performed with prototype computer-aided diagnosis breast MR imaging workstation: reader study. Radiology (2011) 1.01
Estimating three-class ideal observer decision variables for computerized detection and classification of mammographic mass lesions. Med Phys (2004) 1.01
Heme oxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy. PLoS One (2013) 1.00
Disease-specific patient reported outcome tools for systemic lupus erythematosus. Semin Arthritis Rheum (2012) 0.99
Breast US computer-aided diagnosis workstation: performance with a large clinical diagnostic population. Radiology (2008) 0.99
B-cell antigen-receptor signalling in lymphocyte development. Immunology (2003) 0.99
Validation of quantitative analysis of multiparametric prostate MR images for prostate cancer detection and aggressiveness assessment: a cross-imager study. Radiology (2014) 0.99