Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells.

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🔗 View Article (PMC 4004670)

Published in Cell on April 10, 2014

Authors

Mario L Suvà1, Esther Rheinbay2, Shawn M Gillespie2, Anoop P Patel3, Hiroaki Wakimoto4, Samuel D Rabkin4, Nicolo Riggi5, Andrew S Chi6, Daniel P Cahill4, Brian V Nahed4, William T Curry4, Robert L Martuza4, Miguel N Rivera5, Nikki Rossetti5, Simon Kasif7, Samantha Beik8, Sabah Kadri8, Itay Tirosh8, Ivo Wortman8, Alex K Shalek9, Orit Rozenblatt-Rosen8, Aviv Regev10, David N Louis11, Bradley E Bernstein12

Author Affiliations

1: Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address: suva.mario@mgh.harvard.edu.
2: Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
3: Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
4: Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
5: Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
6: Divisions of Neuro-Oncology and Hematology/Oncology and Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
7: Bioinformatics Program, Boston University, Boston, MA 02215, USA; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
8: Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
9: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
10: Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02140, USA.
11: Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
12: Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address: bernstein.bradley@mgh.harvard.edu.

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