Published in Chem Commun (Camb) on May 15, 2014
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Axinellamines as broad-spectrum antibacterial agents: scalable synthesis and biology. J Am Chem Soc (2014) 0.81
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Total synthesis of palau'amine. Nat Commun (2015) 0.76
Asymmetric Synthesis of Axinellamines A and B. Angew Chem Int Ed Engl (2016) 0.75
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Natural products as sources of new drugs over the period 1981-2002. J Nat Prod (2003) 8.03
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Total synthesis of palau'amine. Angew Chem Int Ed Engl (2010) 2.62
Biologically inspired oxidation catalysis. Nature (2008) 2.47
Chasing molecules that were never there: misassigned natural products and the role of chemical synthesis in modern structure elucidation. Angew Chem Int Ed Engl (2005) 2.35
Lessons from the past and charting the future of marine natural products drug discovery and chemical biology. Chem Biol (2012) 2.29
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From protein domains to drug candidates-natural products as guiding principles in the design and synthesis of compound libraries. Angew Chem Int Ed Engl (2002) 2.03
C-H functionalization logic in total synthesis. Chem Soc Rev (2011) 2.00
The pursuit of palau'amine. Angew Chem Int Ed Engl (2007) 2.00
Innate and guided C-H functionalization logic. Acc Chem Res (2011) 1.94
Total synthesis of dimeric pyrrole-imidazole alkaloids: sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton. J Am Chem Soc (2007) 1.65
Some recent advances in the synthesis of polycyclic imidazole-containing marine natural products. Nat Prod Rep (2007) 1.64
A submarine journey: the pyrrole-imidazole alkaloids. Mar Drugs (2009) 1.61
Transition metal-catalyzed C-H activation reactions: diastereoselectivity and enantioselectivity. Chem Soc Rev (2009) 1.61
Chemoselectivity: the mother of invention in total synthesis. Acc Chem Res (2009) 1.44
Structural assignment of tetrabromostyloguanidine: does the relative configuration of the palau'amines need revision? Angew Chem Int Ed Engl (2007) 1.44
Total synthesis of (+/-)-axinellamines A and B. Angew Chem Int Ed Engl (2008) 1.44
Natural products, stylissadines A and B, specific antagonists of the P2X7 receptor, an important inflammatory target. J Org Chem (2007) 1.41
Synthesis of 1,9-dideoxy-pre-axinellamine. Angew Chem Int Ed Engl (2008) 1.39
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Studies toward the total synthesis of axinellamine and massadine. Org Lett (2007) 1.35
Massadine, a novel geranylgeranyltransferase type I inhibitor from the marine sponge Stylissa aff. massa. Org Lett (2003) 1.34
Sceptrin as a potential biosynthetic precursor to complex pyrrole-imidazole alkaloids: the total synthesis of ageliferin. Angew Chem Int Ed Engl (2004) 1.30
Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids. Nat Prod Rep (2011) 1.28
Total synthesis of all (-)-Agelastatin alkaloids. Chem Sci (2010) 1.27
Total syntheses of (+/-)-massadine and massadine chloride. J Am Chem Soc (2008) 1.26
Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines. J Am Chem Soc (2011) 1.25
Synthesis of marine alkaloids from the oroidin family. Angew Chem Int Ed Engl (2008) 1.24
Short total synthesis of (+/-)-sceptrin. J Am Chem Soc (2004) 1.23
Nagelamides A-H, new dimeric bromopyrrole alkaloids from marine sponge Agelas species. J Nat Prod (2004) 1.22
Axinellamines A-D, Novel Imidazo-Azolo-Imidazole Alkaloids from the Australian Marine Sponge Axinella sp. J Org Chem (1999) 1.21
Asymmetric total synthesis of (-)-agelastatin a using sulfinimine (N-sulfinyl imine) derived methodologies. Org Lett (2005) 1.20
Oxidative rearrangement of imidazoles with dimethyldioxirane. Org Lett (2004) 1.19
Scalable, stereocontrolled total syntheses of (±)-axinellamines A and B. J Am Chem Soc (2011) 1.19
Massadine chloride: a biosynthetic precursor of massadine and stylissadine. Angew Chem Int Ed Engl (2007) 1.19
New class of nucleophiles for palladium-catalyzed asymmetric allylic alkylation. Total synthesis of agelastatin A. J Am Chem Soc (2006) 1.18
Enantioselective synthesis of (+)-monobromophakellin and (+)-phakellin: a concise phakellin annulation strategy applicable to Palau'amine. Angew Chem Int Ed Engl (2008) 1.16
Stereocontrolled synthesis of triazacyclopenta[cd]pentalenes by intramolecular 1,3-dipolar cycloaddition reactions of azomethine imines. J Org Chem (2002) 1.16
On the structure of palau'amine: evidence for the revised relative configuration from chemical synthesis. J Am Chem Soc (2007) 1.16
Mechanism of the vinylcyclobutane rearrangement of sceptrin to ageliferin and nagelamide E. Angew Chem Int Ed Engl (2006) 1.15
Palladium-catalyzed direct functionalization of imidazolinone: synthesis of dibromophakellstatin. J Am Chem Soc (2007) 1.15
Stylissadines A and B: the first tetrameric pyrrole-imidazole alkaloids. Org Lett (2006) 1.14
Facile synthesis of the trans-fused azabicyclo[3.3.0]octane core of the palau'amines and the tricyclic core of the axinellamines from a common intermediate. Org Lett (2008) 1.13
Synthesis of (-)-agelastatin A by [3.3] sigmatropic rearrangement of allyl cyanate. Org Lett (2007) 1.13
Synthetic access to the chlorocyclopentane cores of the proposed original and revised structures of palau'amine. Angew Chem Int Ed Engl (2008) 1.13
Short, enantioselective total synthesis of sceptrin and ageliferin by programmed oxaquadricyclane fragmentation. Angew Chem Int Ed Engl (2005) 1.13
Enantioselective strategy to the spirocyclic core of Palau'amine and related bisguanidine marine alkaloids. Org Lett (2001) 1.13
Revisiting the Kinnel-Scheuer hypothesis for the biosynthesis of palau'amine. Chem Commun (Camb) (2010) 1.12
Stable 5-substituted cyclopentadienes for the Diels-Alder cycloaddition and their application to the synthesis of palau'amine. Angew Chem Int Ed Engl (2008) 1.10
Diels-Alder reactions of oroidin and model compounds. Org Lett (2006) 1.09
Exploring symmetry-based logic for a synthesis of palau'amine. J Org Chem (2009) 1.09
Pyrrole aminoimidazole alkaloid metabiosynthesis with marine sponges Agelas conifera and Stylissa caribica. Angew Chem Int Ed Engl (2012) 1.08
New total synthesis of the marine antitumor alkaloid (-)-agelastatin A. Org Lett (2004) 1.07
Organic chemistry in drug discovery. Science (2004) 1.07
Density functional theory guided design of exo-selective dehydroalanine dienophiles for application toward the synthesis of palau'amine. J Org Chem (2007) 1.06
Alkynyliodonium salts in organic synthesis. Application to the total synthesis of (-)-agelastatin A and (-)-agelastatin B. J Am Chem Soc (2002) 1.06
Spirocycloisomerization of tethered alkylidene glycocyamidines: synthesis of a base template common to the palau'amine family of alkaloids. Angew Chem Int Ed Engl (2005) 1.06
Synthesis of sceptrin alkaloids. Org Lett (2004) 1.05
Enantiospecific formal total synthesis of the tumor and GSK-3 beta inhibiting alkaloid, (-)-agelastatin A. Org Lett (2003) 1.03
Synthesis and Diels-Alder reactions of 4-vinylimidazoles. Org Lett (2001) 1.00
Natural products and traditional medicine: turning on a paradigm. J Nat Prod (2012) 1.00
Highly regioselective Diels-Alder reactions toward oroidin alkaloids: use of a tosylvinyl moiety as a nitrogen masking group with adjustable electronics. Org Lett (2005) 0.99
Synthesis of 7-(15)N-Oroidin and evaluation of utility for biosynthetic studies of pyrrole-imidazole alkaloids by microscale (1)H-(15)N HSQC and FTMS. J Nat Prod (2010) 0.99
Enantioselective total synthesis of (+)-dibromophakellstatin. J Am Chem Soc (2003) 0.99
A stereoselective synthesis of the bromopyrrole natural product (-)-agelastatin A. Angew Chem Int Ed Engl (2009) 0.98
A transient N-O-linked Pauson-Khand strategy for the synthesis of the deschloro carbocyclic core of the palau'amines and styloguanidines. Org Lett (2003) 0.97
Structural revisions of natural products by total synthesis. Nat Prod Rep (2009) 0.97
Total synthesis of (-)-agelastatin A. Org Lett (2008) 0.97
New insight into marine alkaloid metabolic pathways: revisiting oroidin biosynthesis. Chembiochem (2011) 0.97
Hypervalent iodine-mediated vicinal syn diazidation: application to the total synthesis of (+/-)-dibromophakellstatin. Org Lett (2004) 0.95
Extending Pummerer reaction chemistry. Synthesis of (+/-)-dibromophakellstatin by oxidative cyclization of an imidazole derivative. Org Lett (2005) 0.94
Synthetic Studies on Palau'amine. Construction of the Cyclopentane Core via an Asymmetric 1,3-Dipolar Cycloaddition. Tetrahedron Lett (2010) 0.93
New antifeedant bromopyrrole alkaloid from the Caribbean sponge Stylissa caribica. J Nat Prod (2001) 0.92
Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis. Bioorg Med Chem (2011) 0.92
Asymmetric synthesis of ageliferin. J Am Chem Soc (2011) 0.92
Total synthesis of the beta-catenin inhibitor, (-)-agelastatin A: a second-generation approach based on radical aminobromination. Org Lett (2009) 0.92
Asymmetric total synthesis of ent-cyclooroidin. Org Lett (2010) 0.91
De novo synthesis of benzosceptrin C and nagelamide H from 7-15N-oroidin: implications for pyrrole-aminoimidazole alkaloid biosynthesis. J Nat Prod (2012) 0.91
Ugi-4-component reaction enabling rapid access to the core fragment of massadine. Org Lett (2010) 0.90
Stereocontrolled synthesis of vicinal diamines by organocatalytic asymmetric Mannich reaction of N-protected aminoacetaldehydes: formal synthesis of (-)-agelastatin A. J Am Chem Soc (2012) 0.90
Extending Pummerer reaction chemistry: studies in the palau'amine synthesis area. J Org Chem (2011) 0.90
Thermochemical Stability of alpha-Amino-alpha-carbonylmethyl Radicals and Their Resonance As Measured by ESR. J Org Chem (1997) 0.90
Total synthesis of (+/-)-agelastatin A, a potent inhibitor of osteopontin-mediated neoplastic transformations. Org Lett (2009) 0.90
Synthesis and anticancer activity of all known (-)-agelastatin alkaloids. J Org Chem (2013) 0.89
A biomimetic route for construction of the [4+2] and [3+2] core skeletons of dimeric pyrrole-imidazole alkaloids and asymmetric synthesis of ageliferins. J Am Chem Soc (2012) 0.89
Toward palau'amine: Hg(OTf)2-catalyzed synthesis of the cyclopentane core. Chemistry (2009) 0.89
Total synthesis of the marine natural product rac-dibromophakellstatin. Angew Chem Int Ed Engl (2005) 0.88
Total synthesis of (-)-agelastatin A: the application of a sequential sigmatropic rearrangement. Org Lett (2009) 0.88
Synthetic (±)-axinellamines deficient in halogen. Angew Chem Int Ed Engl (2012) 0.87
Recent synthetic studies leading to structural revisions of marine natural products. Mar Drugs (2009) 0.86
New bromopyrrole alkaloids from the Indopacific sponge Agelas nakamurai. J Nat Prod (1999) 0.86
Latonduines A and B, new alkaloids isolated from the marine sponge Stylissa carteri: structure elucidation, synthesis, and biogenetic implications. Org Lett (2003) 0.85
Extending Pummerer reaction chemistry: application to the assembly of the pentacyclic core of dibromopalau'amine. Org Lett (2010) 0.85
A likely biogenetic gateway linking 2-aminoimidazolinone metabolites of sponges to proline: spontaneous oxidative conversion of the pyrrole-proline-guanidine pseudo-peptide to dispacamide A. J Am Chem Soc (2004) 0.84
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol (2009) 9.43
Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Mol Cell (2013) 2.97
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Valsalva manoeuver, intra-ocular pressure, cerebrospinal fluid pressure, optic disc topography: Beijing intracranial and intra-ocular pressure study. Acta Ophthalmol (2013) 2.09
Label-free detection of small-molecule-protein interactions by using nanowire nanosensors. Proc Natl Acad Sci U S A (2005) 1.95
Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development. Development (2011) 1.92
Time-resolved shadowgraphs of material ejection in intense femtosecond laser ablation of aluminum. Phys Rev Lett (2007) 1.85
Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration. PLoS Genet (2010) 1.83
Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. Nat Cell Biol (2013) 1.64
MPprimer: a program for reliable multiplex PCR primer design. BMC Bioinformatics (2010) 1.62
Expression analysis and molecular targeting of cyclin-dependent kinases in advanced melanoma. Cell Cycle (2011) 1.54
An indole-3-acetic acid carboxyl methyltransferase regulates Arabidopsis leaf development. Plant Cell (2005) 1.53
Beneficial effects versus toxicity of medium-chain triacylglycerols in rats with NASH. J Hepatol (2007) 1.45
In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains. Dev Biol (2012) 1.43
CoSi particles on silica support as a highly active and selective catalyst for naphthalene hydrogenation. Chem Commun (Camb) (2009) 1.39
Regiocontrol in Mn(III)-mediated oxidative heterobicyclizations: access to the core skeletons of oroidin dimers. Angew Chem Int Ed Engl (2006) 1.38
Effect of chronic alcohol consumption on Hepatic SIRT1 and PGC-1alpha in rats. Biochem Biophys Res Commun (2008) 1.38
Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine. J Biol Chem (2012) 1.33
Common variants on chromosome 2 and risk of primary open-angle glaucoma in the Afro-Caribbean population of Barbados. Proc Natl Acad Sci U S A (2009) 1.30
MFEprimer-2.0: a fast thermodynamics-based program for checking PCR primer specificity. Nucleic Acids Res (2012) 1.24
Structure-activity relationship studies of small-molecule inhibitors of Wnt response. Bioorg Med Chem Lett (2009) 1.24
Expression analysis of Ubc9, the single small ubiquitin-like modifier (SUMO) E2 conjugating enzyme, in normal and malignant tissues. Hum Pathol (2010) 1.16
Microwave synthesis of fluorescent carbon nanoparticles with electrochemiluminescence properties. Chem Commun (Camb) (2009) 1.15
Palladium-catalyzed direct functionalization of imidazolinone: synthesis of dibromophakellstatin. J Am Chem Soc (2007) 1.15
Virus-specific T cell responses in macaques acutely infected with SHIV(sf162p3). Virology (2007) 1.14
Revisiting the Kinnel-Scheuer hypothesis for the biosynthesis of palau'amine. Chem Commun (Camb) (2010) 1.12
Tankyrase is necessary for canonical Wnt signaling during kidney development. Dev Dyn (2010) 1.09
A Highly Selective Vanadium Catalyst for Benzylic C-H Oxidation. Chem Sci (2012) 1.07
Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function. J Biol Chem (2011) 1.06
Alcohol alters hepatic FoxO1, p53, and mitochondrial SIRT5 deacetylation function. Biochem Biophys Res Commun (2008) 1.03
Prediction of protein phosphorylation sites by using the composition of k-spaced amino acid pairs. PLoS One (2012) 1.02
Crb apical polarity proteins maintain zebrafish retinal cone mosaics via intercellular binding of their extracellular domains. Dev Cell (2012) 1.02
Visible light-promoted metal-free C-H activation: diarylketone-catalyzed selective benzylic mono- and difluorination. J Am Chem Soc (2013) 1.01
Distribution of simian immunodeficiency virus target cells in vaginal tissues of normal rhesus macaques: implications for virus transmission. J Reprod Immunol (2006) 1.01
Control of viremia and maintenance of intestinal CD4(+) memory T cells in SHIV(162P3) infected macaques after pathogenic SIV(MAC251) challenge. Virology (2009) 1.01
Reliability analysis of the Ahringer Caenorhabditis elegans RNAi feeding library: a guide for genome-wide screens. BMC Genomics (2011) 1.01
High temperature requirement factor A1 (HTRA1) gene regulates angiogenesis through transforming growth factor-β family member growth differentiation factor 6. J Biol Chem (2011) 1.01
Synthesis and structure revision of nakiterpiosin. J Am Chem Soc (2009) 1.00
Biomimetic design of elastomer surface pattern for friction control under wet conditions. Bioinspir Biomim (2013) 0.98
Arabidopsis AtBECLIN 1/AtAtg6/AtVps30 is essential for pollen germination and plant development. Cell Res (2007) 0.98
The development of highly potent inhibitors for porcupine. J Med Chem (2013) 0.97
Double-positive CD21+CD27+ B cells are highly proliferating memory cells and their distribution differs in mucosal and peripheral tissues. PLoS One (2011) 0.97
High-performance energy-storage architectures from carbon nanotubes and nanocrystal building blocks. Adv Mater (2012) 0.96
Visible light-promoted metal-free sp(3)-C-H fluorination. Chem Commun (Camb) (2014) 0.96
An approach to the core skeleton of lancifodilactone F. Org Lett (2008) 0.95
Promising carbons for supercapacitors derived from fungi. Adv Mater (2011) 0.94
Comparison of the vaginal environment of Macaca mulatta and Macaca nemestrina throughout the menstrual cycle. Am J Reprod Immunol (2014) 0.94
Induction of terminal differentiation in melanoma cells on downregulation of beta-amyloid precursor protein. J Invest Dermatol (2009) 0.93
Bioinformatics resources and tools for conformational B-cell epitope prediction. Comput Math Methods Med (2013) 0.92
Asymmetric synthesis of ageliferin. J Am Chem Soc (2011) 0.92
Simian immunodeficiency virus infection in rhesus macaques induces selective tissue specific B cell defects in double positive CD21+CD27+ memory B cells. Clin Immunol (2011) 0.91
A biomimetic route for construction of the [4+2] and [3+2] core skeletons of dimeric pyrrole-imidazole alkaloids and asymmetric synthesis of ageliferins. J Am Chem Soc (2012) 0.89
One-pot green synthesis of biocompatible arginine-stabilized magnetic nanoparticles. Nanotechnology (2009) 0.89
Brain protection by using innominate artery cannulation during aortic arch surgery. Ann Thorac Surg (2008) 0.89
CD8 down-regulation and functional impairment of SIV-specific cytotoxic T lymphocytes in lymphoid and mucosal tissues during SIV infection. J Leukoc Biol (2013) 0.89
Expression of the muscle atrophy factor muscle atrophy F-box is suppressed by testosterone. Endocrinology (2008) 0.89
Role of medium-chain triglycerides in the alcohol-mediated cytochrome P450 2E1 induction of mitochondria. Alcohol Clin Exp Res (2007) 0.89
Prediction of lysine ubiquitylation with ensemble classifier and feature selection. Int J Mol Sci (2011) 0.89
Early divergent host responses in SHIVsf162P3 and SIVmac251 infected macaques correlate with control of viremia. PLoS One (2011) 0.87
Suppressing the high-level expression and function of ATM in advanced-stage melanomas does not sensitize the cells to ionizing radiation. Cancer Biol Ther (2009) 0.87
Novel micelle formulation of curcumin for enhancing antitumor activity and inhibiting colorectal cancer stem cells. Int J Nanomedicine (2012) 0.87
Gluten-sensitive enteropathy coincides with decreased capability of intestinal T cells to secrete IL-17 and IL-22 in a macaque model for celiac disease. Clin Immunol (2013) 0.87
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Tubulin-destabilizing agent BPR0L075 induces vascular-disruption in human breast cancer mammary fat pad xenografts. PLoS One (2012) 0.86
Epitope prediction based on random peptide library screening: benchmark dataset and prediction tools evaluation. Molecules (2011) 0.86
LC-MS/MS method for the determination of melamine in rat plasma: toxicokinetic study in Sprague-Dawley rats. J Sep Sci (2009) 0.86
Mucosal immunology of HIV infection. Immunol Rev (2013) 0.86
Chronic leucine supplementation increases body weight and insulin sensitivity in rats on high-fat diet likely by promoting insulin signaling in insulin-target tissues. Mol Nutr Food Res (2013) 0.85
Huaier aqueous extract inhibits colorectal cancer stem cell growth partially via downregulation of the Wnt/β-catenin pathway. Oncol Lett (2013) 0.85
Chloride coordination by oligoureas: from mononuclear crescents to dinuclear foldamers. Org Lett (2012) 0.85
Chemical and biological studies of nakiterpiosin and nakiterpiosinone. J Am Chem Soc (2010) 0.85
VizPrimer: a web server for visualized PCR primer design based on known gene structure. Bioinformatics (2011) 0.84
Influence of the addition of transition metals (Cr, Zr, Mo) on the properties of MnOx-FeOx catalysts for low-temperature selective catalytic reduction of NOx by Ammonia. J Colloid Interface Sci (2012) 0.83
Lymphangiogenesis and its relationship with lymphatic metastasis and prognosis in malignant melanoma. Anat Rec (Hoboken) (2008) 0.83
Pantoea stewartii subsp. stewartii exhibits surface motility, which is a critical aspect of Stewart's wilt disease development on maize. Mol Plant Microbe Interact (2008) 0.83
Position-specific analysis and prediction of protein pupylation sites based on multiple features. Biomed Res Int (2013) 0.83
TCP transcription factors are critical for the coordinated regulation of isochorismate synthase 1 expression in Arabidopsis thaliana. Plant J (2015) 0.83
The DEAD/DEAH box helicase, DDX11, is essential for the survival of advanced melanomas. Mol Cancer (2012) 0.83
Enrichment of colorectal cancer stem cells through epithelial-mesenchymal transition via CDH1 knockdown. Mol Med Rep (2012) 0.83
ADAM22 plays an important role in cell adhesion and spreading with the assistance of 14-3-3. Biochem Biophys Res Commun (2005) 0.82
Characteristics and recent trends of sulfur dioxide at urban, rural, and background sites in north China: effectiveness of control measures. J Environ Sci (China) (2012) 0.82
Discovery of hapten-specific scFv from a phage display library and applications for HER2-positive tumor imaging. Bioconjug Chem (2014) 0.82
Echolocation click sounds from wild inshore finless porpoise (Neophocaena phocaenoides sunameri) with comparisons to the sonar of riverine N. p. asiaeorientalis. J Acoust Soc Am (2007) 0.82
Synthesis of cysteamine-coated CdTe quantum dots and its application in mercury (II) detection. Anal Chim Acta (2012) 0.81
PepMapper: a collaborative web tool for mapping epitopes from affinity-selected peptides. PLoS One (2012) 0.81
Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants. Chem Commun (Camb) (2012) 0.81
Using support vector machine and evolutionary profiles to predict antifreeze protein sequences. Int J Mol Sci (2012) 0.80
Controlled synthesis of phase-pure InAs nanowires on Si(111) by diminishing the diameter to 10 nm. Nano Lett (2014) 0.80
Simple alcohols promoted direct C-H arylation of unactivated arenes with aryl halides. Chem Commun (Camb) (2013) 0.80
Prediction of bioluminescent proteins using auto covariance transformation of evolutional profiles. Int J Mol Sci (2012) 0.80
Leucine facilitates the insulin-stimulated glucose uptake and insulin signaling in skeletal muscle cells: involving mTORC1 and mTORC2. Amino Acids (2014) 0.80