Published in Genome Res on May 16, 2014
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Mammalian Brain Development is Accompanied by a Dramatic Increase in Bipolar DNA Methylation. Sci Rep (2016) 0.75
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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol (2009) 235.12
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Human DNA methylomes at base resolution show widespread epigenomic differences. Nature (2009) 34.27
DNA methylation patterns and epigenetic memory. Genes Dev (2002) 33.83
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (2009) 32.97
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Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell (2008) 28.29
A chromatin landmark and transcription initiation at most promoters in human cells. Cell (2007) 23.41
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Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature (2000) 14.91
The Polycomb group protein EZH2 directly controls DNA methylation. Nature (2005) 13.67
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature (1988) 13.21
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature (2000) 12.97
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DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature (2007) 11.14
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet (2009) 10.54
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DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature (2011) 8.75
A clustering approach for identification of enriched domains from histone modification ChIP-Seq data. Bioinformatics (2009) 8.33
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature (2011) 8.31
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci U S A (2000) 8.12
Dynamic changes in the human methylome during differentiation. Genome Res (2010) 7.96
Global epigenomic reconfiguration during mammalian brain development. Science (2013) 6.14
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. Nature (2011) 5.50
Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet (2011) 4.25
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science (2011) 4.12
Epigenetic instability in ES cells and cloned mice. Science (2001) 4.08
Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell (2012) 4.00
Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions. Genome Res (2011) 3.57
Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine. Science (2012) 3.45
Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates. Cell (2011) 3.39
Genomic distribution and inter-sample variation of non-CpG methylation across human cell types. PLoS Genet (2011) 2.98
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In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases. PLoS Genet (2012) 2.70
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Hairpin-bisulfite PCR: assessing epigenetic methylation patterns on complementary strands of individual DNA molecules. Proc Natl Acad Sci U S A (2003) 2.35
Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis. Cell Rep (2013) 2.10
H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes. Mol Cell (2010) 1.85
Processive methylation of hemimethylated CpG sites by mouse Dnmt1 DNA methyltransferase. J Biol Chem (2004) 1.77
Fidelity of the methylation pattern and its variation in the genome. Genome Res (2003) 1.71
'Leveling' the playing field for analyses of single-base resolution DNA methylomes. Trends Genet (2012) 1.67
Comparative epigenomic annotation of regulatory DNA. Cell (2012) 1.62
Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment. Cell Stem Cell (2007) 1.56
Molecular barcodes detect redundancy and contamination in hairpin-bisulfite PCR. Nucleic Acids Res (2004) 1.44
Genome-wide uH2A localization analysis highlights Bmi1-dependent deposition of the mark at repressed genes. PLoS Genet (2009) 1.36
Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase. Nucleic Acids Res (2006) 1.36
Genome-wide quantitative assessment of variation in DNA methylation patterns. Nucleic Acids Res (2011) 1.23
A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network. Nucleic Acids Res (2012) 1.21
Epigenetic stability increases extensively during Drosophila follicle stem cell differentiation. Proc Natl Acad Sci U S A (2010) 1.12
Decreased fidelity in replicating CpG methylation patterns in cancer cells. Cancer Res (2005) 1.09
Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming. Hum Mol Genet (2012) 1.07
Genome-wide dynamic changes of DNA methylation of repetitive elements in human embryonic stem cells and fetal fibroblasts. Genomics (2011) 0.95
Spontaneous differentiation of mouse embryonic stem cells in vitro: characterization by global gene expression profiles. Biochem Biophys Res Commun (2005) 0.94
Instability of retroviral DNA methylation in embryonic stem cells. Stem Cells (2008) 0.94
STATISTICAL INFERENCE OF TRANSMISSION FIDELITY OF DNA METHYLATION PATTERNS OVER SOMATIC CELL DIVISIONS IN MAMMALS. Ann Appl Stat (2010) 0.90
Decreased fidelity in replicating DNA methylation patterns in cancer cells leads to dense methylation of a CpG island. Curr Top Microbiol Immunol (2006) 0.83
Statistical inference of in vivo properties of human DNA methyltransferases from double-stranded methylation patterns. PLoS One (2012) 0.80