Published in Nucleic Acids Res on October 16, 2012
DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control. Nat Genet (2015) 1.26
Effect of prenatal arsenic exposure on DNA methylation and leukocyte subpopulations in cord blood. Epigenetics (2014) 1.22
COHCAP: an integrative genomic pipeline for single-nucleotide resolution DNA methylation analysis. Nucleic Acids Res (2013) 1.08
Whole-genome fingerprint of the DNA methylome during human B cell differentiation. Nat Genet (2015) 1.07
Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes. Epigenetics (2014) 1.01
The dynamics of DNA methylation fidelity during mouse embryonic stem cell self-renewal and differentiation. Genome Res (2014) 1.00
Molecular determinants of regulatory T cell development: the essential roles of epigenetic changes. Front Immunol (2013) 0.98
Methylomics of gene expression in human monocytes. Hum Mol Genet (2013) 0.97
Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers. Genome Res (2015) 0.96
S-adenosylmethionine levels regulate the schwann cell DNA methylome. Neuron (2014) 0.95
Effect of sex hormones on n-3 polyunsaturated fatty acid biosynthesis in HepG2 cells and in human primary hepatocytes. Prostaglandins Leukot Essent Fatty Acids (2013) 0.93
Epigenetic modulation of the immune function: a potential target for tolerance. Epigenetics (2013) 0.90
Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures. Nucleic Acids Res (2015) 0.85
PTPRG inhibition by DNA methylation and cooperation with RAS gene activation in childhood acute lymphoblastic leukemia. Int J Cancer (2014) 0.85
Regulation of the transcriptional program by DNA methylation during human αβ T-cell development. Nucleic Acids Res (2014) 0.84
Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition. Leukemia (2016) 0.83
Leukocyte-adjusted epigenome-wide association studies of blood from solid tumor patients. Epigenetics (2014) 0.82
Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients. EMBO Mol Med (2015) 0.82
The DNA methylation profile of activated human natural killer cells. Epigenetics (2016) 0.80
Genome-wide CpG island methylation and intergenic demethylation propensities vary among different tumor sites. Nucleic Acids Res (2015) 0.80
The role of genomics in common variable immunodeficiency disorders. Clin Exp Immunol (2017) 0.79
Genome-wide DNA methylation analysis in precursor B-cells. Epigenetics (2014) 0.79
Monozygotic twins discordant for common variable immunodeficiency reveal impaired DNA demethylation during naïve-to-memory B-cell transition. Nat Commun (2015) 0.78
Enlarged leukocyte referent libraries can explain additional variance in blood-based epigenome-wide association studies. Epigenomics (2016) 0.77
Association between DNA methyltransferases 3B gene polymorphisms and the susceptibility to acute myeloid leukemia in Chinese Han population. PLoS One (2013) 0.77
Integrated methylome and transcriptome analysis reveals novel regulatory elements in pediatric acute lymphoblastic leukemia. Epigenetics (2015) 0.77
Bone marrow transcriptome and epigenome profiles of equine common variable immunodeficiency patients unveil block of B lymphocyte differentiation. Clin Immunol (2015) 0.77
A Chemical Probe Targets DNA 5-Formylcytosine Sites and Inhibits TDG Excision, Polymerases Bypass, and Gene Expression. Chem Sci (2014) 0.77
Distinct genomic and epigenomic features demarcate hypomethylated blocks in colon cancer. BMC Cancer (2016) 0.75
Systematic comparison of lncRNAs with protein coding mRNAs in population expression and their response to environmental change. BMC Plant Biol (2017) 0.75
The Expression Pattern of the Pre-B Cell Receptor Components Correlates with Cellular Stage and Clinical Outcome in Acute Lymphoblastic Leukemia. PLoS One (2016) 0.75
Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol (2004) 101.91
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res (2003) 52.74
Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc Int Conf Intell Syst Mol Biol (1994) 37.96
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 20.32
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat Biotechnol (2009) 11.18
Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature (2010) 9.81
CpG islands and the regulation of transcription. Genes Dev (2011) 9.50
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs). Genome Res (2008) 4.84
The DNA methylation paradox. Trends Genet (1999) 4.40
Something about SUMO inhibits transcription. Curr Opin Genet Dev (2005) 4.05
Transcriptional control of early B cell development. Annu Rev Immunol (2004) 3.22
The protean nature of cells in the B lymphocyte lineage. Immunity (2007) 2.64
Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. J Biol Chem (2004) 2.63
Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells. Genes Cells (2007) 2.51
Mammalian cytosine methylation at a glance. J Cell Sci (2009) 2.43
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data. BMC Bioinformatics (2010) 2.24
DNA methylation status predicts cell type-specific enhancer activity. EMBO J (2011) 1.98
Hematopoietic cytokines, transcription factors and lineage commitment. Oncogene (2002) 1.93
Expanding role of ubiquitination in NF-κB signaling. Cell Res (2010) 1.89
Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription. Nat Immunol (2004) 1.82
Estrogen alters thresholds for B cell apoptosis and activation. J Clin Invest (2002) 1.76
Global DNA demethylation during mouse erythropoiesis in vivo. Science (2011) 1.73
Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis. Immunity (2009) 1.67
Differentially expressed genes are marked by histone 3 lysine 9 trimethylation in human cancer cells. Oncogene (2007) 1.58
Evolving views on the genealogy of B cells. Nat Rev Immunol (2008) 1.52
A promoter DNA demethylation landscape of human hematopoietic differentiation. Nucleic Acids Res (2011) 1.49
The transcription factor Spi-B is expressed in plasmacytoid DC precursors and inhibits T-, B-, and NK-cell development. Blood (2002) 1.32
From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitment. Curr Opin Immunol (2010) 1.25
Small RNAs guide hematopoietic cell differentiation and function. J Immunol (2010) 1.24
Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation. EMBO J (2007) 1.22
Factors and networks that underpin early hematopoiesis. Semin Immunol (2011) 1.03
Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue. Diabetologia (2010) 1.03
Role of PI3K in the generation and survival of B cells. Immunol Rev (2010) 0.97
Differential roles of estrogen receptors α and β in control of B-cell maturation and selection. Mol Med (2010) 0.97
Normal B-1a cell development requires B cell-intrinsic NFATc1 activity. Proc Natl Acad Sci U S A (2003) 0.97
Transcriptional control of B cell development and function. Gene (2004) 0.95
Molecular resolution of the B cell landscape. Curr Opin Immunol (2011) 0.93
Transcriptional regulation by DNA methylation. Cancer Treat Rev (2011) 0.91
Brca1 in immunoglobulin gene conversion and somatic hypermutation. DNA Repair (Amst) (2007) 0.88
Fetal bone marrow as a source of stem cells for in utero or postnatal transplantation. Br J Haematol (2000) 0.88
IL-3 and stromal cell-derived factor synergistically stimulate the growth of pre-B cell lines cloned from long-term lymphoid bone marrow cultures. J Immunol (1989) 0.88
Human recombinant IL-3 stimulates B cell differentiation. J Immunol (1989) 0.86
Cutting edge: Identification of a hybrid cytokine consisting of IL-7 and the beta-chain of the hepatocyte growth factor/scatter factor. J Immunol (2001) 0.83
Inhibitory effect of interleukin 3 on early development of human B-lymphopoiesis. Br J Haematol (2001) 0.80
DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics (2012) 9.31
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet (2009) 7.07
Dental x-rays and risk of meningioma. Cancer (2012) 5.99
FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity. Nat Genet (2007) 5.93
Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero. Science (2008) 5.76
Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat Genet (2009) 5.13
Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. N Engl J Med (2015) 5.03
Assessment of cumulative evidence on genetic associations: interim guidelines. Int J Epidemiol (2007) 4.96
Interventions to prevent skin cancer by reducing exposure to ultraviolet radiation: a systematic review. Am J Prev Med (2004) 4.07
Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer (2008) 3.98
Protective association of aspirin/NSAIDs and esophageal cancer: a systematic review and meta-analysis. Gastroenterology (2003) 3.90
Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions. BMC Bioinformatics (2008) 3.89
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
A road map for efficient and reliable human genome epidemiology. Nat Genet (2006) 3.21
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst (2010) 3.18
DNA topoisomerase II in therapy-related acute promyelocytic leukemia. N Engl J Med (2005) 3.06
The landscape of recombination in African Americans. Nature (2011) 3.06
DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J Natl Cancer Inst (2010) 2.87
Epidemiology of intracranial meningioma. Neurosurgery (2005) 2.60
Population- and community-based recruitment of African Americans and Latinos: the San Francisco Bay Area Lung Cancer Study. Am J Epidemiol (2003) 2.52
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet (2011) 2.43
Epidemiology of brain tumors. Neurol Clin (2007) 2.38
Leukemia in twins: lessons in natural history. Blood (2003) 2.37
Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B. J Clin Invest (2013) 2.04
Genome-wide association study of glioma and meta-analysis. Hum Genet (2012) 1.96
A meta-analysis of the association between day-care attendance and childhood acute lymphoblastic leukaemia. Int J Epidemiol (2010) 1.95
Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma. Carcinogenesis (2009) 1.94
Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. Crit Rev Toxicol (2008) 1.93
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
Blood-based profiles of DNA methylation predict the underlying distribution of cell types: a validation analysis. Epigenetics (2013) 1.79
History of allergies among adults with glioma and controls. Int J Cancer (2002) 1.78
Distinct germ line polymorphisms underlie glioma morphologic heterogeneity. Cancer Genet (2011) 1.77
Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers. Cancer Epidemiol Biomarkers Prev (2012) 1.76
Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake. PLoS Genet (2010) 1.74
Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients. J Clin Invest (2007) 1.73
Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome. Cancer Res (2009) 1.73
A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. Nat Genet (2012) 1.73
In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia. Blood (2002) 1.71
The Pathways Study: a prospective study of breast cancer survivorship within Kaiser Permanente Northern California. Cancer Causes Control (2008) 1.70
PTEN expression in non-small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration. Hum Pathol (2005) 1.67
Comorbidities and survival in a large cohort of patients with newly diagnosed myelodysplastic syndromes. Leuk Res (2009) 1.57
Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests. Cancer Epidemiol Biomarkers Prev (2008) 1.56
Molecular basis of selective atrial fibrosis due to overexpression of transforming growth factor-β1. Cardiovasc Res (2013) 1.55
Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma. Neuro Oncol (2007) 1.53
The cost of breast cancer screening in the Medicare population. JAMA Intern Med (2013) 1.53
Serum IgE, tumor epidermal growth factor receptor expression, and inherited polymorphisms associated with glioma survival. Cancer Res (2006) 1.52
Cytogenetics of Hispanic and White children with acute lymphoblastic leukemia in California. Cancer Epidemiol Biomarkers Prev (2006) 1.51
Understanding regional variation in Medicare expenditures for initial episodes of prostate cancer care. Med Care (2014) 1.50
A population-based study of the Arg399Gln polymorphism in X-ray repair cross- complementing group 1 (XRCC1) and risk of pancreatic adenocarcinoma. Cancer Res (2002) 1.45
Accuracy of multiplexed Illumina platform-based single-nucleotide polymorphism genotyping compared between genomic and whole genome amplified DNA collected from multiple sources. Cancer Epidemiol Biomarkers Prev (2006) 1.45
Diagnostic X-rays and risk of childhood leukaemia. Int J Epidemiol (2010) 1.43
SNPLogic: an interactive single nucleotide polymorphism selection, annotation, and prioritization system. Nucleic Acids Res (2008) 1.42
Polymorphisms of LIG4, BTBD2, HMGA2, and RTEL1 genes involved in the double-strand break repair pathway predict glioblastoma survival. J Clin Oncol (2010) 1.40
Searching for common stem cells of the hepatic and hematopoietic systems in the human fetal liver: CD34+ cytokeratin 7/8+ cells express markers for stellate cells. J Hepatol (2004) 1.40
Identifying differentially expressed genes from microarray experiments via statistic synthesis. Bioinformatics (2004) 1.39
Peripheral blood DNA methylation profiles are indicative of head and neck squamous cell carcinoma: an epigenome-wide association study. Epigenetics (2012) 1.35
IgE, allergy, and risk of glioma: update from the San Francisco Bay Area Adult Glioma Study in the temozolomide era. Int J Cancer (2009) 1.35
Reduced immunoglobulin E and allergy among adults with glioma compared with controls. Cancer Res (2004) 1.34
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. Genet Epidemiol (2012) 1.34
A population-based, case-control study of polymorphisms in carcinogen-metabolizing genes, smoking, and pancreatic adenocarcinoma risk. J Natl Cancer Inst (2002) 1.33
Quantitative reconstruction of leukocyte subsets using DNA methylation. Genome Biol (2014) 1.32
Ethnic difference in daycare attendance, early infections, and risk of childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev (2005) 1.32
DNA quantification of whole genome amplified samples for genotyping on a multiplexed bead array platform. Cancer Epidemiol Biomarkers Prev (2007) 1.31
Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals. J Immunol (2007) 1.31
DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression. Neuro Oncol (2011) 1.29
Identification of methylated genes associated with aggressive bladder cancer. PLoS One (2010) 1.27
Novel childhood ALL susceptibility locus BMI1-PIP4K2A is specifically associated with the hyperdiploid subtype. Blood (2013) 1.25
NQO1 polymorphisms and de novo childhood leukemia: a HuGE review and meta-analysis. Am J Epidemiol (2008) 1.25
Meat and meat mutagens and risk of prostate cancer in the Agricultural Health Study. Cancer Epidemiol Biomarkers Prev (2008) 1.23
Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking. PLoS One (2009) 1.23
Allergy-related polymorphisms influence glioma status and serum IgE levels. Cancer Epidemiol Biomarkers Prev (2007) 1.22
MDR1 gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev (2007) 1.21
Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology. Neuro Oncol (2013) 1.20