Published in J Biol Chem on July 16, 2014
Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport. Mol Biol Cell (2015) 0.81
Uptake and processing of the cytolethal distending toxin by mammalian cells. Toxins (Basel) (2014) 0.80
Pseudomonas Exotoxin A: optimized by evolution for effective killing. Front Microbiol (2015) 0.80
Keeping It All Going-Complement Meets Metabolism. Front Immunol (2017) 0.78
Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans. PLoS Pathog (2015) 0.77
Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus. Sci Rep (2016) 0.75
Making Bunyaviruses Talk: Interrogation Tactics to Identify Host Factors Required for Infection. Viruses (2016) 0.75
In vitro and in vivo effects of a recombinant anti-PSMA immunotoxin in combination with docetaxel against prostate cancer. Oncotarget (2016) 0.75
Cross-inhibition of pathogenic agents and the host proteins they exploit. Sci Rep (2016) 0.75
Developing a Novel Gene-Delivery Vector System Using the Recombinant Fusion Protein of Pseudomonas Exotoxin A and Hyperthermophilic Archaeal Histone HPhA. PLoS One (2015) 0.75
Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting. J Cell Biol (2017) 0.75
Host determinants of adeno-associated viral vector entry. Curr Opin Virol (2017) 0.75
RNA-guided human genome engineering via Cas9. Science (2013) 48.29
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell (2013) 24.00
Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol (2009) 13.01
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell (1991) 11.51
Thrombin signalling and protease-activated receptors. Nature (2000) 9.27
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell (1996) 8.25
The mechanisms of vesicle budding and fusion. Cell (2004) 7.96
A rapid and general assay for monitoring endogenous gene modification. Methods Mol Biol (2010) 6.77
Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol (2002) 6.37
Ebola virus entry requires the cholesterol transporter Niemann-Pick C1. Nature (2011) 5.68
Haploid genetic screens in human cells identify host factors used by pathogens. Science (2009) 4.91
The DNA sequence and analysis of human chromosome 6. Nature (2003) 4.75
Processing of the Ebola virus glycoprotein by the proprotein convertase furin. Proc Natl Acad Sci U S A (1998) 4.33
Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle. Dev Cell (2007) 4.26
Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1984) 3.98
Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis. Trends Cell Biol (1999) 3.50
Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution. Proc Natl Acad Sci U S A (1986) 3.41
Role of diacylglycerol in PKD recruitment to the TGN and protein transport to the plasma membrane. Science (2001) 3.39
Conformational biosensors reveal GPCR signalling from endosomes. Nature (2013) 3.29
Coat proteins: shaping membrane transport. Nat Rev Mol Cell Biol (2003) 3.10
The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP. Immunity (1997) 2.93
Exiting the Golgi complex. Nat Rev Mol Cell Biol (2008) 2.75
Regulation of secretory vesicle traffic by Rab small GTPases. Cell Mol Life Sci (2008) 2.71
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells. Cell Stem Cell (2011) 2.69
Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D. Cell (1999) 2.67
A heterotrimeric G protein, G alpha i-3, on Golgi membranes regulates the secretion of a heparan sulfate proteoglycan in LLC-PK1 epithelial cells. J Cell Biol (1991) 2.58
Complete vesiculation of Golgi membranes and inhibition of protein transport by a novel sea sponge metabolite, ilimaquinone. Cell (1993) 2.44
The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A. J Biol Chem (1992) 2.40
Global gene disruption in human cells to assign genes to phenotypes by deep sequencing. Nat Biotechnol (2011) 2.23
EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking. J Cell Biol (2003) 2.16
CdtA, CdtB, and CdtC form a tripartite complex that is required for cytolethal distending toxin activity. Infect Immun (2001) 2.13
Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry. Science (2013) 1.91
Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation. J Cell Biol (1994) 1.80
Role of heterotrimeric G proteins in membrane traffic. Mol Biol Cell (1992) 1.79
A guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer. FEBS J (2011) 1.70
Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits. Biochemistry (2005) 1.51
Identification of host cell factors required for intoxication through use of modified cholera toxin. J Cell Biol (2011) 1.47
Site-specific protein labeling via sortase-mediated transpeptidation. Curr Protoc Protein Sci (2009) 1.43
Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry. Nature (2005) 1.41
The KDEL retrieval system is exploited by Pseudomonas exotoxin A, but not by Shiga-like toxin-1, during retrograde transport from the Golgi complex to the endoplasmic reticulum. J Cell Sci (1999) 1.40
Regulation of Golgi structure through heterotrimeric G proteins. Cell (1997) 1.38
Transport according to GARP: receiving retrograde cargo at the trans-Golgi network. Trends Cell Biol (2010) 1.32
Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT). Proc Natl Acad Sci U S A (2011) 1.31
Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions. Nat Protoc (2013) 1.25
DNA sequence and analysis of human chromosome 9. Nature (2004) 1.21
Membrane fission: the biogenesis of transport carriers. Annu Rev Biochem (2012) 1.19
Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity. J Mol Biol (2001) 1.18
An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. J Cell Biol (2009) 1.08
rsly1 binding to syntaxin 5 is required for endoplasmic reticulum-to-Golgi transport but does not promote SNARE motif accessibility. Mol Biol Cell (2003) 1.08
Evidence for an interaction of neuronostatin with the orphan G protein-coupled receptor, GPR107. Am J Physiol Regul Integr Comp Physiol (2012) 1.03
Retrograde transport of protein toxins through the Golgi apparatus. Histochem Cell Biol (2013) 1.03
Furin regulates both the activation of Pseudomonas exotoxin A and the Quantity of the toxin receptor expressed on target cells. Infect Immun (1996) 1.02
Attachment of Chlamydia trachomatis L2 to host cells requires sulfation. Proc Natl Acad Sci U S A (2012) 1.00
Three-dimensional structure of the rSly1 N-terminal domain reveals a conformational change induced by binding to syntaxin 5. J Mol Biol (2004) 0.96
Regulation of constitutive cargo transport from the trans-Golgi network to plasma membrane by Golgi-localized G protein betagamma subunits. J Biol Chem (2010) 0.94
Binding of the cytosolic p200 protein to Golgi membranes is regulated by heterotrimeric G proteins. J Cell Sci (1993) 0.93
Intact sphingomyelin biosynthetic pathway is essential for intracellular transport of influenza virus glycoproteins. Proc Natl Acad Sci U S A (2013) 0.92
The biosynthesis and biological function of diphthamide. Crit Rev Biochem Mol Biol (2013) 0.92
LRP 1 B functions as a receptor for Pseudomonas exotoxin. Biochim Biophys Acta (2005) 0.89
Human GPR107 and murine Gpr108 are members of the LUSTR family of proteins found in both plants and animals, having similar topology to G-protein coupled receptors. DNA Seq (2007) 0.81
Himasthla elongata: effect of infection on expression of the LUSTR-like receptor mRNA in common periwinkle haemocytes. Exp Parasitol (2009) 0.80