Published in Biochemistry on April 26, 2005
Cotranslational and posttranslational N-glycosylation of polypeptides by distinct mammalian OST isoforms. Cell (2009) 2.10
Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex. Cell (2011) 1.86
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GPR107, a G-protein-coupled receptor essential for intoxication by Pseudomonas aeruginosa exotoxin A, localizes to the Golgi and is cleaved by furin. J Biol Chem (2014) 0.88
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Transcription factor Nrf1 is topologically repartitioned across membranes to enable target gene transactivation through its acidic glucose-responsive domains. PLoS One (2014) 0.80
N-linked glycosylation and homeostasis of the endoplasmic reticulum. Curr Opin Cell Biol (2016) 0.79
Mammalian cells lacking either the cotranslational or posttranslocational oligosaccharyltransferase complex display substrate-dependent defects in asparagine linked glycosylation. Sci Rep (2016) 0.79
Reduced expression of the oligosaccharyltransferase exacerbates protein hypoglycosylation in cells lacking the fully assembled oligosaccharide donor. Glycobiology (2015) 0.78
Comprehensive proteomic analysis of nonintegrin laminin receptor interacting proteins. J Proteome Res (2012) 0.77
DC2 and keratinocyte-associated protein 2 (KCP2), subunits of the oligosaccharyltransferase complex, are regulators of the gamma-secretase-directed processing of amyloid precursor protein (APP). J Biol Chem (2011) 0.77
Expanding the Molecular and Clinical Phenotype of SSR4-CDG. Hum Mutat (2015) 0.77
Gene amplification and functional diversification of melanocortin 4 receptor at an extremely polymorphic locus controlling sexual maturation in the platyfish. Genetics (2013) 0.77
OST4 is a subunit of the mammalian oligosaccharyltransferase required for efficient N-glycosylation. J Cell Sci (2013) 0.77
Dissecting the molecular organization of the translocon-associated protein complex. Nat Commun (2017) 0.75
Bacterial N-Glycosylation Efficiency Is Dependent on the Structural Context of Target Sequons. J Biol Chem (2016) 0.75
Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nat Chem Biol (2009) 2.70
Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein. Nat Struct Mol Biol (2005) 2.33
Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex. Cell (2011) 1.86
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Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway. J Clin Invest (2009) 1.59
Lens proteomics: the accumulation of crystallin modifications in the mouse lens with age. Invest Ophthalmol Vis Sci (2002) 1.55
Identification of protein modifications using MS/MS de novo sequencing and the OpenSea alignment algorithm. J Proteome Res (2005) 1.54
The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice. J Neurosci (2010) 1.54
Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system. Cell (2007) 1.44
Molecular architecture of the chick vestibular hair bundle. Nat Neurosci (2013) 1.43
High-throughput identification of proteins and unanticipated sequence modifications using a mass-based alignment algorithm for MS/MS de novo sequencing results. Anal Chem (2004) 1.42
Aquaporin-4 dynamics in orthogonal arrays in live cells visualized by quantum dot single particle tracking. Mol Biol Cell (2008) 1.38
Two-dimensional liquid chromatography study of the human whole saliva proteome. J Proteome Res (2004) 1.35
On the biomarkers and mechanisms of konzo, a distinct upper motor neuron disease associated with food (cassava) cyanogenic exposure. Food Chem Toxicol (2010) 1.34
Accurate annotation of peptide modifications through unrestrictive database search. J Proteome Res (2007) 1.30
The membrane proteome of the mouse lens fiber cell. Mol Vis (2009) 1.30
Deamidation, but not truncation, decreases the urea stability of a lens structural protein, betaB1-crystallin. Biochemistry (2002) 1.25
Techniques for accurate protein identification in shotgun proteomic studies of human, mouse, bovine, and chicken lenses. J Ocul Biol Dis Infor (2009) 1.25
p97 functions as an auxiliary factor to facilitate TM domain extraction during CFTR ER-associated degradation. EMBO J (2006) 1.24
Global organization and function of mammalian cytosolic proteasome pools: Implications for PA28 and 19S regulatory complexes. Mol Biol Cell (2006) 1.17
Lens proteomics: analysis of rat crystallin sequences and two-dimensional electrophoresis map. Invest Ophthalmol Vis Sci (2002) 1.15
Decreased heat stability and increased chaperone requirement of modified human betaB1-crystallins. Mol Vis (2002) 1.14
Sequence-specific retention and regulated integration of a nascent membrane protein by the endoplasmic reticulum Sec61 translocon. Mol Biol Cell (2008) 1.11
A novel tripartite motif involved in aquaporin topogenesis, monomer folding and tetramerization. Nat Struct Mol Biol (2007) 1.10
Ectopic Pax6 expression disturbs lens fiber cell differentiation. Invest Ophthalmol Vis Sci (2004) 1.08
Distinct energy metabolism of auditory and vestibular sensory epithelia revealed by quantitative mass spectrometry using MS2 intensity. Proc Natl Acad Sci U S A (2012) 1.05
Methionine sulfoxide reductase A (MsrA) restores alpha-crystallin chaperone activity lost upon methionine oxidation. Biochim Biophys Acta (2009) 1.05
Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome. J Biol Chem (2008) 1.04
Role of Hsp90 in biogenesis of the beta-cell ATP-sensitive potassium channel complex. Mol Biol Cell (2010) 1.03
The hydrogen peroxide reactivity of peptidylglycine monooxygenase supports a Cu(II)-superoxo catalytic intermediate. J Biol Chem (2005) 1.03
Proteomic profiling of human retinal and choroidal endothelial cells reveals molecular heterogeneity related to tissue of origin. Mol Vis (2007) 1.02
Reliable detection of deamidated peptides from lens crystallin proteins using changes in reversed-phase elution times and parent ion masses. J Proteome Res (2007) 1.02
Laser light-scattering evidence for an altered association of beta B1-crystallin deamidated in the connecting peptide. Protein Sci (2004) 1.02
Thermal instability of ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) channel function: protection by single suppressor mutations and inhibiting channel activity. Biochemistry (2012) 1.01
Mass measurements of C-terminally truncated alpha-crystallins from two-dimensional gels identify Lp82 as a major endopeptidase in rat lens. Mol Cell Proteomics (2002) 1.00
Molecular mechanisms of aquaporin biogenesis by the endoplasmic reticulum Sec61 translocon. Biochim Biophys Acta (2006) 1.00
The cotranslational contacts between ribosome-bound nascent polypeptides and the subunits of the hetero-oligomeric chaperonin TRiC probed by photocross-linking. J Biol Chem (2005) 1.00
Na+/K+-ATPase α1 identified as an abundant protein in the blood-labyrinth barrier that plays an essential role in the barrier integrity. PLoS One (2011) 0.99
Calpain-specific proteolysis in primate retina: Contribution of calpains in cell death. Invest Ophthalmol Vis Sci (2006) 0.99
Role of the retinal vascular endothelial cell in ocular disease. Prog Retin Eye Res (2012) 0.99
The DMM complex prevents spreading of DNA methylation from transposons to nearby genes in Neurospora crassa. Genes Dev (2010) 0.98
Biophysical properties of gammaC-crystallin in human and mouse eye lens: the role of molecular dipoles. J Mol Biol (2007) 0.98
Ligand-driven vectorial folding of ribosome-bound human CFTR NBD1. Mol Cell (2011) 0.97
Engineering the substrate specificity of ADP-ribosyltransferases for identifying direct protein targets. J Am Chem Soc (2014) 0.97
Endoplasmic reticulum protein quality control is determined by cooperative interactions between Hsp/c70 protein and the CHIP E3 ligase. J Biol Chem (2013) 0.96
HIF1α protein stability is increased by acetylation at lysine 709. J Biol Chem (2012) 0.96
Stable liquid glucagon formulations for rescue treatment and bi-hormonal closed-loop pancreas. Curr Diab Rep (2012) 0.95
Quantification of isotopically overlapping deamidated and 18o-labeled peptides using isotopic envelope mixture modeling. J Proteome Res (2009) 0.94
Mechanisms of glucagon degradation at alkaline pH. Peptides (2013) 0.93
Kinetic analysis of ribosome-bound fluorescent proteins reveals an early, stable, cotranslational folding intermediate. J Biol Chem (2011) 0.93
Proteome analysis of lens epithelia, fibers, and the HLE B-3 cell line. Invest Ophthalmol Vis Sci (2003) 0.92
The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation. Am J Physiol Cell Physiol (2013) 0.92
Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum-associated degradation. Mol Biol Cell (2011) 0.91
Proteomic and sequence analysis of chicken lens crystallins reveals alternate splicing and translational forms of beta B2 and beta A2 crystallins. Invest Ophthalmol Vis Sci (2004) 0.90
N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2. J Gen Physiol (2011) 0.90
Mechanisms of CFTR Folding at the Endoplasmic Reticulum. Front Pharmacol (2012) 0.90
In vitro reconstitution of CFTR biogenesis and degradation. Methods Mol Med (2002) 0.89
Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein. J Biol Chem (2014) 0.89
Calreticulin binds to gentamicin and reduces drug-induced ototoxicity. Toxicol Sci (2011) 0.88
Protein database and quantitative analysis considerations when integrating genetics and proteomics to compare mouse strains. J Proteome Res (2011) 0.88
Uncoupling proteasome peptidase and ATPase activities results in cytosolic release of an ER polytopic protein. J Cell Sci (2006) 0.88
Susceptibility of ovine lens crystallins to proteolytic cleavage during formation of hereditary cataract. Invest Ophthalmol Vis Sci (2008) 0.87
Correlation of actin crosslinker and capper expression levels with stereocilia growth phases. Mol Cell Proteomics (2013) 0.87
Verification and spatial localization of aquaporin-5 in the ocular lens. Exp Eye Res (2013) 0.86
Differential stability of biogenesis intermediates reveals a common pathway for aquaporin-1 topological maturation. J Biol Chem (2004) 0.86
Evidence for stabilization of aquaporin-2 folding mutants by N-linked glycosylation in endoplasmic reticulum. Am J Physiol Cell Physiol (2004) 0.86
Altered patterns of phosphorylation in cultured mouse lenses during development of buthionine sulfoximine cataracts. Exp Eye Res (2002) 0.85
Cooperativity and flexibility of cystic fibrosis transmembrane conductance regulator transmembrane segments participate in membrane localization of a charged residue. J Biol Chem (2002) 0.85
Proteomics and phosphoproteomics analysis of human lens fiber cell membranes. Invest Ophthalmol Vis Sci (2013) 0.85
Expressed sequence tag analysis of guinea pig (Cavia porcellus) eye tissues for NEIBank. Mol Vis (2008) 0.84
General utility of the chicken betaB1-crystallin promoter to drive protein expression in lens fiber cells of transgenic mice. Transgenic Res (2002) 0.84
An energy-dependent maturation step is required for release of the cystic fibrosis transmembrane conductance regulator from early endoplasmic reticulum biosynthetic machinery. J Biol Chem (2005) 0.84
Molecular mechanism of P-glycoprotein assembly into cellular membranes. Curr Protein Pept Sci (2002) 0.84
Epstein-Barr viral BNLF2a protein hijacks the tail-anchored protein insertion machinery to block antigen processing by the transport complex TAP. J Biol Chem (2011) 0.83
Aberrant folding of a mutant Stat5b causes growth hormone insensitivity and proteasomal dysfunction. J Biol Chem (2005) 0.82
Human and monkey lenses cultured with calcium ionophore form alphaB-crystallin lacking the C-terminal lysine, a prominent feature of some human cataracts. Invest Ophthalmol Vis Sci (2009) 0.82
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine? Exp Eye Res (2012) 0.81
Quantitative proteomics identifies a change in glial glutamate metabolism at the time of female puberty. Mol Cell Endocrinol (2006) 0.81
Changes in solvent accessibility of wild-type and deamidated βB2-crystallin following complex formation with αA-crystallin. Exp Eye Res (2012) 0.81
The cytoplasmic domain of rhesus cytomegalovirus Rh178 interrupts translation of major histocompatibility class I leader peptide-containing proteins prior to translocation. J Virol (2011) 0.81
In vitro incorporation of nonnatural amino acids into protein using tRNA(Cys)-derived opal, ochre, and amber suppressor tRNAs. RNA (2010) 0.81
A systems approach implicates nuclear receptor targeting in the Atp7b(-/-) mouse model of Wilson's disease. Metallomics (2012) 0.81
Biochemical stabilization of glucagon at alkaline pH. Diabetes Technol Ther (2014) 0.80
Reticulocyte lysate as a model system to study endoplasmic reticulum membrane protein degradation. Methods Mol Biol (2005) 0.80
In vitro methods for CFTR biogenesis. Methods Mol Biol (2011) 0.80
Solvent accessibility of betaB2-crystallin and local structural changes due to deamidation at the dimer interface. Exp Eye Res (2010) 0.80
CFTR Folding Consortium: methods available for studies of CFTR folding and correction. Methods Mol Biol (2011) 0.79
Sequence and peptide map of guinea pig aquaporin 0. Mol Vis (2004) 0.79
Shotgun proteomic analysis of S-thiolation sites of guinea pig lens nuclear crystallins following oxidative stress in vivo. Mol Vis (2013) 0.79
Proteomic analysis of biopsied human colonic mucosa. J Pediatr Gastroenterol Nutr (2010) 0.79
Fibrinogen Hershey IV: a novel dysfibrinogen with a gammaV411I mutation in the integrin alpha(IIb)beta(3) binding site. Thromb Haemost (2008) 0.79
Dissection of the human multipotent adult progenitor cell secretome by proteomic analysis. Stem Cells Transl Med (2013) 0.77
Mass spectrometry in proteomics. Methods (2005) 0.77
Newborn mouse lens proteome and its alteration by lysine 6 mutant ubiquitin. J Proteome Res (2014) 0.75