Assessing the validity, responsiveness and meaningfulness of the Hidradenitis Suppurativa Clinical Response (HiSCR) as the clinical endpoint for hidradenitis suppurativa treatment.

PubWeight™: 1.63‹?› | Rank: Top 4%

🔗 View Article (PMID 25040429)

Published in Br J Dermatol on November 11, 2014

Authors

A B Kimball1, G B E Jemec, M Yang, A Kageleiry, J E Signorovitch, M M Okun, Y Gu, K Wang, P Mulani, M Sundaram

Author Affiliations

1: Department of Dermatology, Harvard Medical School, Boston, MA, U.S.A.

Associated clinical trials:

MABp1 IN HIDRADENITIS SUPPURATIVA REFRACTORY TO ADALIMUMAB | NCT02643654

Laser Hair Removal for Treatment of Pilonidal Disease | NCT03949140

Articles by these authors

(truncated to the top 100)

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature (2000) 47.15

Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med (1999) 26.42

Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science (1995) 8.31

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell (1998) 6.79

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature (1999) 6.37

Sequence and genomic organization of Norwalk virus. Virology (1993) 6.25

Pairwise end sequencing: a unified approach to genomic mapping and sequencing. Genomics (1995) 4.83

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J Biol Chem (1999) 4.56

Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells. Proc Natl Acad Sci U S A (1975) 4.38

Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana. Genes Dev (1999) 4.35

Nucleotide sequence of the amylase gene from Bacillus subtilis. Nucleic Acids Res (1983) 4.33

Early Homo and associated artefacts from Asia. Nature (1995) 4.23

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci U S A (1995) 4.22

Right 25 bp terminus sequence of the nopaline T-DNA is essential for and determines direction of DNA transfer from agrobacterium to the plant genome. Cell (1984) 4.09

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell (1999) 3.76

Autism-like behavioral phenotypes in BTBR T+tf/J mice. Genes Brain Behav (2007) 3.76

A mini binary vector series for plant transformation. Plant Mol Biol (1999) 3.75

Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene (2009) 3.64

Intracellular distributions of mechanochemical proteins in cultured fibroblasts. Proc Natl Acad Sci U S A (1977) 3.63

Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells. J Clin Invest (1998) 3.54

Complete genomic sequence and analysis of the prion protein gene region from three mammalian species. Genome Res (1998) 3.44

Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A. Proc Natl Acad Sci U S A (1992) 3.38

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching. J Exp Med (1998) 3.37

Efficacies of different preparations of glucosamine for the treatment of osteoarthritis: a meta-analysis of randomised, double-blind, placebo-controlled trials. Int J Clin Pract (2013) 3.16

A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia. Cell (2001) 3.13

Susceptible chiasmate configurations of chromosome 21 predispose to non-disjunction in both maternal meiosis I and meiosis II. Nat Genet (1996) 3.13

Titin: major myofibrillar components of striated muscle. Proc Natl Acad Sci U S A (1979) 2.96

When the brain changes its mind: interocular grouping during binocular rivalry. Proc Natl Acad Sci U S A (1996) 2.93

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J Mol Biol (1999) 2.92

Distribution-free estimation of age-related centiles. Ann Hum Biol (1988) 2.87

Heterotopic ossification: a review. Skeletal Radiol (2005) 2.86

HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells. Leukemia (2010) 2.83

A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function. Proc Natl Acad Sci U S A (2001) 2.77

Localization of Bacillus subtilis sacU(Hy) mutations to two linked genes with similarities to the conserved procaryotic family of two-component signalling systems. J Bacteriol (1988) 2.71

Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy. Cell (1999) 2.68

Activation of human cyclin-dependent kinases in vitro. Mol Biol Cell (1992) 2.68

Identification of a genetically distinct subspecies of Mycobacterium kansasii. J Clin Microbiol (1992) 2.66

Phosphorus limitation of nitrogen fixation by Trichodesmium in the central Atlantic Ocean. Nature (2001) 2.65

Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs. Nat Med (1997) 2.61

The structure of trp RNA-binding attenuation protein. Nature (1995) 2.55

An approach to nearest neighbor analysis of membrane proteins. Application to the human erythrocyte membrane of a method employing cleavable cross-linkages. J Biol Chem (1974) 2.53

Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction. Anal Biochem (2000) 2.53

Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system. Nat Genet (2000) 2.53

Bringing a family practice model of health to the People's Republic of China. Fam Med (2001) 2.52

Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers. Anal Chem (2001) 2.42

naked cuticle encodes an inducible antagonist of Wnt signalling. Nature (2000) 2.35

A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells. EMBO J (1995) 2.34

Identification of the pleiotropic sacQ gene of Bacillus subtilis. J Bacteriol (1986) 2.33

Sarcomere-associated cytoskeletal lattices in striated muscle. Review and hypothesis. Cell Muscle Motil (1985) 2.30

Endoscopic tri-modal imaging for detection of early neoplasia in Barrett's oesophagus: a multi-centre feasibility study using high-resolution endoscopy, autofluorescence imaging and narrow band imaging incorporated in one endoscopy system. Gut (2007) 2.30

Site-Specific Nick in the T-DNA Border Sequence as a Result of Agrobacterium vir Gene Expression. Science (1987) 2.26

Role of inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells. J Cell Biol (1996) 2.21

Development of a real-time PCR method for Firmicutes and Bacteroidetes in faeces and its application to quantify intestinal population of obese and lean pigs. Lett Appl Microbiol (2008) 2.19

Comprehensive processing, display and analysis for in vivo MR spectroscopic imaging. NMR Biomed (2006) 2.19

GAL4 enhancer traps expressed in the embryo, larval brain, imaginal discs, and ovary of Drosophila. Dev Dyn (1997) 2.18

PDGF-D, a new protease-activated growth factor. Nat Cell Biol (2001) 2.17

A network of transverse and longitudinal intermediate filaments is associated with sarcomeres of adult vertebrate skeletal muscle. J Cell Biol (1983) 2.16

Fluorescent localization of contractile proteins in tissue culture cells. Methods Enzymol (1982) 2.12

Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs. Proc Natl Acad Sci U S A (1993) 2.12

Filamin, a new high-molecular-weight protein found in smooth muscle and nonmuscle cells. Purification and properties of chicken gizzard filamin. Biochemistry (1977) 2.11

Early and early disseminated phases of Lyme disease in the rhesus monkey: a model for infection in humans. Infect Immun (1993) 2.11

Randomized phase III study comparing irinotecan combined with 5-fluorouracil and folinic acid to cisplatin combined with 5-fluorouracil in chemotherapy naive patients with advanced adenocarcinoma of the stomach or esophagogastric junction. Ann Oncol (2008) 2.09

An immunodominant conserved region within the variable domain of VlsE, the variable surface antigen of Borrelia burgdorferi. J Immunol (1999) 2.09

Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency. Blood (2000) 2.08

Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. Proc Natl Acad Sci U S A (1992) 2.07

In vivo thickness measurement of basal cell carcinoma and actinic keratosis with optical coherence tomography and 20-MHz ultrasound. Br J Dermatol (2009) 2.07

A multilevel model framework for meta-analysis of clinical trials with binary outcomes. Stat Med (2000) 2.06

Hemodynamic predictors of myocardial oxygen consumption during static and dynamic exercise. Circulation (1974) 2.01

Can clinical and radiological features predict recurrence in solitary keratocystic odontogenic tumors? Oral Surg Oral Med Oral Pathol Oral Radiol (2013) 2.01

Host specificity of Helicobacter pylori strains and host responses in experimentally challenged nonhuman primates. Gastroenterology (1999) 1.96

Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo. EMBO J (1997) 1.96

MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1. Oncogene (2011) 1.94

VirD proteins of Agrobacterium tumefaciens are required for the formation of a covalent DNA--protein complex at the 5' terminus of T-strand molecules. EMBO J (1988) 1.93

Construction and characterization of a half million clone BAC library of durum wheat ( Triticum turgidum ssp. durum). Theor Appl Genet (2003) 1.92

School physical education: effect of the Child and Adolescent Trial for Cardiovascular Health. Prev Med (1996) 1.92

Comparative genomics of the human and mouse T cell receptor loci. Immunity (2001) 1.92

Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development. Proc Natl Acad Sci U S A (2001) 1.91

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization. Mol Cell Biol (1999) 1.91

Epidemiology of influenza A(H1N1)v virus infection in Japan, May-June 2009. Euro Surveill (2009) 1.91

Nucleotide sequence of cloned rat serum albumin messenger RNA. Proc Natl Acad Sci U S A (1981) 1.90

Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation. Cancer Res (1993) 1.89

Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases. Proc Natl Acad Sci U S A (1993) 1.89

Identification of a family of closely related human ubiquitin conjugating enzymes. J Biol Chem (1995) 1.89

Expression of the human cell surface glycoconjugates Lewis x and Lewis y by Helicobacter pylori isolates is related to cagA status. Infect Immun (1996) 1.88

Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate. Oncogene (2010) 1.87

Interaction of filamin with f-actin in solution. Proc Natl Acad Sci U S A (1977) 1.87

A mixture model with random-effects components for clustering correlated gene-expression profiles. Bioinformatics (2006) 1.85

Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile. J Cell Biol (1991) 1.85

Identification of the promoter region of the Escherichia coli major cold shock gene, cspA. J Bacteriol (1992) 1.85

Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice. Proc Natl Acad Sci U S A (2000) 1.83

Power to detect linkage based on multiple sets of data in the presence of locus heterogeneity: comparative evaluation of model-based linkage methods for affected sib pair data. Hum Hered (2001) 1.82

Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil. Clin Cancer Res (1999) 1.82

RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling. J Biol Chem (1999) 1.81

Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization. Proc Natl Acad Sci U S A (2001) 1.80

A genome-wide analysis of Arabidopsis Rop-interactive CRIB motif-containing proteins that act as Rop GTPase targets. Plant Cell (2001) 1.80

Sequence homology between RNAs encoding rat alpha-fetoprotein and rat serum albumin. Proc Natl Acad Sci U S A (1981) 1.79

Decreased blood pressure response in mice deficient of the alpha1b-adrenergic receptor. Proc Natl Acad Sci U S A (1997) 1.76

Passive tension and stiffness of vertebrate skeletal and insect flight muscles: the contribution of weak cross-bridges and elastic filaments. Biophys J (1993) 1.75

ALL-1 partial duplication in acute leukemia. Proc Natl Acad Sci U S A (1994) 1.74

Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial. Br J Dermatol (2008) 1.72