Published in Methods Enzymol on January 01, 1982
Tubulin dynamics in cultured mammalian cells. J Cell Biol (1984) 6.46
Molecular and functional characterization of the Salmonella invasion gene invA: homology of InvA to members of a new protein family. J Bacteriol (1992) 6.08
Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation. Infect Immun (1987) 5.92
Spindle microtubule dynamics in sea urchin embryos: analysis using a fluorescein-labeled tubulin and measurements of fluorescence redistribution after laser photobleaching. J Cell Biol (1984) 5.23
Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase. J Cell Biol (1988) 2.72
Recycling of transferrin receptors in A431 cells is inhibited during mitosis. EMBO J (1984) 2.42
An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane. EMBO J (1994) 2.10
Assembly properties of fluorescein-labeled tubulin in vitro before and after fluorescence bleaching. J Cell Biol (1984) 2.03
Newly synthesized G protein of vesicular stomatitis virus is not transported to the Golgi complex in mitotic cells. J Cell Biol (1985) 1.94
A monoclonal antibody to the heavy chain of clathrin. EMBO J (1983) 1.94
Antibodies against lysosomal membranes reveal a 100,000-mol-wt protein that cross-reacts with purified H+,K+ ATPase from gastric mucosa. J Cell Biol (1984) 1.59
Invasion of epithelial cells by Actinobacillus actinomycetemcomitans: a dynamic, multistep process. Infect Immun (1996) 1.56
Arrestin mobilizes signaling proteins to the cytoskeleton and redirects their activity. J Mol Biol (2007) 1.52
The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex. Proc Natl Acad Sci U S A (2005) 1.43
Arrest of Listeria movement in host cells by a bacterial ActA analogue: implications for actin-based motility. Proc Natl Acad Sci U S A (1994) 1.41
Purification and properties of transgelin: a transformation and shape change sensitive actin-gelling protein. J Cell Biol (1993) 1.35
Interaction of fluorescently-labeled contractile proteins with the cytoskeleton in cell models. J Cell Biol (1984) 1.29
Exchangeability of alpha-actinin in living cardiac fibroblasts and muscle cells. J Cell Biol (1985) 1.25
Epoxide hydrolase is a marker for the smooth endoplasmic reticulum in rat liver. EMBO J (1985) 1.23
Aldolase exists in both the fluid and solid phases of cytoplasm. J Cell Biol (1988) 1.22
Formation and alignment of Z lines in living chick myotubes microinjected with rhodamine-labeled alpha-actinin. J Cell Biol (1986) 1.19
HT-29 cells are an in vitro model for the generation of cell polarity in epithelia during embryonic differentiation. Proc Natl Acad Sci U S A (1988) 1.11
Disruption of the three cytoskeletal networks in mammalian cells does not affect transcription, translation, or protein translocation changes induced by heat shock. Mol Cell Biol (1985) 1.06
Inhibition of Listeria locomotion by mosquito oostatic factor, a natural oligoproline peptide uncoupler of profilin action. Infect Immun (1995) 0.93
Effect of functional end groups of silane self-assembled monolayer surfaces on apatite formation, fibronectin adsorption and osteoblast cell function. J Tissue Eng Regen Med (2009) 0.90
Spatial pattern of myosin phosphorylation in contracting smooth muscle cells: evidence for contractile zones. J Cell Biol (1988) 0.90
Association of microinjected myosin and its subfragments with myofibrils in living muscle cells. J Cell Biol (1988) 0.90
Flow-through comb electroporation device for delivery of macromolecules. Anal Chem (2013) 0.87
Preparation of functionally active cell-permeable peptides by single-step ligation of two peptide modules. Proc Natl Acad Sci U S A (1998) 0.82
Glutathione reductase is essential for host defense against bacterial infection. Free Radic Biol Med (2013) 0.81
Microfilaments in cellular and developmental processes. Science (1971) 13.56
Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science (1995) 8.31
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature (1999) 6.37
Sequence and genomic organization of Norwalk virus. Virology (1993) 6.25
Identification of clones that encode chicken tropomyosin by direct immunological screening of a cDNA expression library. Proc Natl Acad Sci U S A (1983) 6.00
Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. Proc Natl Acad Sci U S A (1978) 5.91
Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins. Science (1986) 4.99
Microinjection and localization of a 130K protein in living fibroblasts: a relationship to actin and fibronectin. Cell (1980) 4.87
Pairwise end sequencing: a unified approach to genomic mapping and sequencing. Genomics (1995) 4.83
Rapid purification of mammalian 70,000-dalton stress proteins: affinity of the proteins for nucleotides. Mol Cell Biol (1985) 4.75
The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity. Nature (1984) 4.61
Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J Biol Chem (1999) 4.56
A rapid purification of alpha-actinin, filamin, and a 130,000-dalton protein from smooth muscle. J Biol Chem (1980) 4.50
Co-existence of vinculin and a vinculin-like protein of higher molecular weight in smooth muscle. J Biol Chem (1982) 4.42
Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells. Proc Natl Acad Sci U S A (1975) 4.38
Antibody-induced linkages of plasma membrane proteins to intracellular actomyosin-containing filaments in cultured fibroblasts. Proc Natl Acad Sci U S A (1977) 4.23
Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci U S A (1995) 4.22
Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells. J Biol Chem (1984) 4.20
Right 25 bp terminus sequence of the nopaline T-DNA is essential for and determines direction of DNA transfer from agrobacterium to the plant genome. Cell (1984) 4.09
Microinjection of the oncogene form of the human H-ras (T-24) protein results in rapid proliferation of quiescent cells. Cell (1984) 3.81
A mini binary vector series for plant transformation. Plant Mol Biol (1999) 3.75
Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation. Cell (1985) 3.73
Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene (2009) 3.64
Intracellular distributions of mechanochemical proteins in cultured fibroblasts. Proc Natl Acad Sci U S A (1977) 3.63
10-nm filaments are induced to collapse in living cells microinjected with monoclonal and polyclonal antibodies against tubulin. J Cell Biol (1984) 3.51
Complete genomic sequence and analysis of the prion protein gene region from three mammalian species. Genome Res (1998) 3.44
Reversion from transformed to normal phenotype by inhibition of protein synthesis in rat kidney cells infected with a temperature-sensitive mutant of Rous sarcoma virus. Proc Natl Acad Sci U S A (1976) 3.38
Titin: major myofibrillar components of striated muscle. Proc Natl Acad Sci U S A (1979) 2.96
p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps. Mol Cell Biol (2000) 2.96
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J Mol Biol (1999) 2.92
Purification of the major mammalian heat shock proteins. J Biol Chem (1982) 2.79
Biochemical characterization of the mammalian stress proteins and identification of two stress proteins as glucose- and Ca2+-ionophore-regulated proteins. J Biol Chem (1983) 2.78
Use of the avidin-biotin complex for the localization of actin and myosin with fluorescence microscopy. J Cell Biol (1977) 2.74
Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase. J Cell Biol (1988) 2.72
An approach to nearest neighbor analysis of membrane proteins. Application to the human erythrocyte membrane of a method employing cleavable cross-linkages. J Biol Chem (1974) 2.53
Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction. Anal Biochem (2000) 2.53
The common 90-kd protein component of non-transformed '8S' steroid receptors is a heat-shock protein. EMBO J (1985) 2.50
Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers. Anal Chem (2001) 2.42
Non-muscle alpha actinins are calcium-sensitive actin-binding proteins. Nature (1981) 2.35
naked cuticle encodes an inducible antagonist of Wnt signalling. Nature (2000) 2.35
Isolation of phosphorylated peptides and proteins on ion exchange papers. Anal Biochem (1978) 2.33
Direct visualization of fluorescein-labeled microtubules in vitro and in microinjected fibroblasts. J Cell Biol (1981) 2.33
Sarcomere-associated cytoskeletal lattices in striated muscle. Review and hypothesis. Cell Muscle Motil (1985) 2.30
The antibody-induced clustering and endocytosis of HLA antigens on cultured human fibroblasts. Cell (1980) 2.27
Actin in the green alga, Nitella. Proc Natl Acad Sci U S A (1974) 2.27
Site-Specific Nick in the T-DNA Border Sequence as a Result of Agrobacterium vir Gene Expression. Science (1987) 2.26
Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. Genes Dev (2000) 2.21
Development of a real-time PCR method for Firmicutes and Bacteroidetes in faeces and its application to quantify intestinal population of obese and lean pigs. Lett Appl Microbiol (2008) 2.19
Molecular and cellular effects of heat-shock and related treatments of mammalian tissue-culture cells. Cold Spring Harb Symp Quant Biol (1982) 2.18
A network of transverse and longitudinal intermediate filaments is associated with sarcomeres of adult vertebrate skeletal muscle. J Cell Biol (1983) 2.16
Filamin, a new high-molecular-weight protein found in smooth muscle and nonmuscle cells. Purification and properties of chicken gizzard filamin. Biochemistry (1977) 2.11
Concanavalin-A-induced transmembrane linkage of concanavalin A surface receptors to intracellular myosin-containing filaments. Proc Natl Acad Sci U S A (1976) 2.09
RB-dependent S-phase response to DNA damage. Mol Cell Biol (2000) 2.08
Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. Proc Natl Acad Sci U S A (1992) 2.07
Hemodynamic predictors of myocardial oxygen consumption during static and dynamic exercise. Circulation (1974) 2.01
Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells. Mol Cell Biol (1988) 2.00
Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression. Genes Dev (1998) 1.99
Cell surface-associated structural proteins in connective tissue cells. Proc Natl Acad Sci U S A (1977) 1.99
Disruption of the in vivo distribution of the intermediate filaments in fibroblasts through the microinjection of a specific monoclonal antibody. Cell (1981) 1.98
Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo. EMBO J (1997) 1.96
Microinjection of fluorescently labeled alpha-actinin into living fibroblasts. Proc Natl Acad Sci U S A (1979) 1.95
VirD proteins of Agrobacterium tumefaciens are required for the formation of a covalent DNA--protein complex at the 5' terminus of T-strand molecules. EMBO J (1988) 1.93
Comparative genomics of the human and mouse T cell receptor loci. Immunity (2001) 1.92
HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. J Biol Chem (1993) 1.91
A Rab1 mutant affecting guanine nucleotide exchange promotes disassembly of the Golgi apparatus. J Cell Biol (1994) 1.91
Optimal spatial requirements for the location of basic residues in peptide substrates for the cyclic AMP-dependent protein kinase. J Biol Chem (1980) 1.88
Interaction of filamin with f-actin in solution. Proc Natl Acad Sci U S A (1977) 1.87
A mixture model with random-effects components for clustering correlated gene-expression profiles. Bioinformatics (2006) 1.85
Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile. J Cell Biol (1991) 1.85
Power to detect linkage based on multiple sets of data in the presence of locus heterogeneity: comparative evaluation of model-based linkage methods for affected sib pair data. Hum Hered (2001) 1.82
Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil. Clin Cancer Res (1999) 1.82
Transmembrane linkage of fibronectin to intracellular actin-containing filaments in cultured human fibroblasts. Ann N Y Acad Sci (1978) 1.79
Passive tension and stiffness of vertebrate skeletal and insect flight muscles: the contribution of weak cross-bridges and elastic filaments. Biophys J (1993) 1.75
Elevation of tubulin levels by microinjection suppresses new tubulin synthesis. Nature (1983) 1.68
The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elements. Nature (1988) 1.66
Incorporating language phenotypes strengthens evidence of linkage to autism. Am J Med Genet (2001) 1.65
Interaction of MHC class I molecules with the transporter associated with antigen processing. Science (1994) 1.65
Interplay between passive tension and strong and weak binding cross-bridges in insect indirect flight muscle. A functional dissection by gelsolin-mediated thin filament removal. J Gen Physiol (1993) 1.64
A bacterial peptide acting as a plant nuclear targeting signal: the amino-terminal portion of Agrobacterium VirD2 protein directs a beta-galactosidase fusion protein into tobacco nuclei. Proc Natl Acad Sci U S A (1990) 1.63
Titin is an extraordinarily long, flexible, and slender myofibrillar protein. Proc Natl Acad Sci U S A (1984) 1.63
Identification of an N2 line protein of striated muscle. Proc Natl Acad Sci U S A (1980) 1.63
The ultrasensitive silver "protein" stain also detects nanograms of nucleic acids. Biochem Biophys Res Commun (1981) 1.63
Assessing the validity, responsiveness and meaningfulness of the Hidradenitis Suppurativa Clinical Response (HiSCR) as the clinical endpoint for hidradenitis suppurativa treatment. Br J Dermatol (2014) 1.63
Epidermal growth factor stimulates guanine nucleotide binding activity and phosphorylation of ras oncogene proteins. Nature (1984) 1.62
Purification of titin and nebulin. Methods Enzymol (1982) 1.62
Hematopoietic malignancies demonstrate loss-of-function mutations of BAX. Blood (1998) 1.61
Transient reversion of ras oncogene-induced cell transformation by antibodies specific for amino acid 12 of ras protein. Nature (1985) 1.61
Studies on the kinetic mechanism of the catalytic subunit of the cAMP-dependent protein kinase. J Biol Chem (1983) 1.61
Nebulette: a 107 kD nebulin-like protein in cardiac muscle. Cell Motil Cytoskeleton (1995) 1.61
The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. Genomics (1994) 1.60
Characterization of antibodies to smooth muscle myosin kinase and their use in localizing myosin kinase in nonmuscle cells. Proc Natl Acad Sci U S A (1981) 1.55
Mechanochemical proteins, cell motility and cell-cell contacts: the localization of mechanochemical proteins inside cultured cells at the edge of an in vitro "wound". J Cell Physiol (1979) 1.55
Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor C alpha/C delta region. Genomics (1992) 1.55
Structured entry of radiology reports using World Wide Web technology. Radiographics (1996) 1.54
A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum. Proc Natl Acad Sci U S A (1994) 1.53
Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex. EMBO J (1994) 1.53
Somatic PKD2 mutations in individual kidney and liver cysts support a "two-hit" model of cystogenesis in type 2 autosomal dominant polycystic kidney disease. J Am Soc Nephrol (1999) 1.50