Published in Dev Biol on July 27, 2014
The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. Nat Genet (2016) 1.55
Control of vertebrate core planar cell polarity protein localization and dynamics by Prickle 2. Development (2015) 0.89
From Planar Cell Polarity to Ciliogenesis and Back: The Curious Tale of the PPE and CPLANE proteins. Trends Cell Biol (2017) 0.83
The Drosophila planar polarity gene multiple wing hairs directly regulates the actin cytoskeleton. Development (2015) 0.79
The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells. J Cell Biol (2015) 0.79
Tissue morphodynamics: Translating planar polarity cues into polarized cell behaviors. Semin Cell Dev Biol (2016) 0.77
The planar cell polarity effector protein Wdpcp (Fritz) controls epithelial cell cortex dynamics via septins and actomyosin. Biochem Biophys Res Commun (2014) 0.76
A Novel Frizzled-Based Screening Tool Identifies Genetic Modifiers of Planar Cell Polarity in Drosophila Wings. G3 (Bethesda) (2016) 0.75
Planar Cell Polarity Effector Fritz Interacts with Dishevelled and Has Multiple Functions in Regulating PCP. G3 (Bethesda) (2017) 0.75
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (1993) 58.26
An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases. Proc Natl Acad Sci U S A (2007) 12.13
Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31. Genetics (2004) 9.98
The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron (1992) 5.26
The white gene as a marker in a new P-element vector for gene transfer in Drosophila. Nucleic Acids Res (1987) 4.92
Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature (2003) 4.56
Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev (1998) 4.51
Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell (1998) 4.49
Vectors for P-mediated transformation in Drosophila. Biotechnology (1988) 4.18
Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. Cell (1999) 4.07
Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet (2006) 3.97
Tissue/planar cell polarity in vertebrates: new insights and new questions. Development (2007) 3.66
Regulation of planar cell polarity by Smurf ubiquitin ligases. Cell (2009) 3.50
Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nat Cell Biol (2002) 3.49
Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics (1995) 3.45
Mathematical modeling of planar cell polarity to understand domineering nonautonomy. Science (2005) 3.42
The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. J Neurosci (2006) 3.36
A genetic analysis of the determination of cuticular polarity during development in Drosophila melanogaster. J Embryol Exp Morphol (1982) 3.36
Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell (2002) 3.03
Principles of planar polarity in animal development. Development (2011) 2.94
Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. Science (2010) 2.89
Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells. J Cell Biol (1993) 2.80
Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling. Genes Dev (2001) 2.78
Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning. Development (2003) 2.67
Asymmetric localization of frizzled and the establishment of cell polarity in the Drosophila wing. Mol Cell (2001) 2.41
Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nat Genet (2005) 2.36
Van Gogh: a new Drosophila tissue polarity gene. Genetics (1998) 2.23
Strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila. Development (1998) 2.14
The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family. Development (1999) 2.12
Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling. EMBO J (2003) 2.09
The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization. Dev Cell (2001) 2.08
The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs. Genes Dev (1999) 1.98
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol (2009) 1.90
The planar cell polarity gene strabismus regulates convergence and extension and neural fold closure in Xenopus. Dev Biol (2002) 1.84
Tissue polarity points from cells that have higher Frizzled levels towards cells that have lower Frizzled levels. Curr Biol (1997) 1.80
Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes. Development (2004) 1.80
The prickle-related gene in vertebrates is essential for gastrulation cell movements. Curr Biol (2003) 1.76
The genetic control of tissue polarity in Drosophila. Bioessays (1992) 1.70
Microtubules enable the planar cell polarity of airway cilia. Curr Biol (2012) 1.59
A single frizzled protein has a dual function in tissue polarity. Development (1994) 1.58
Regulation of convergent extension in Xenopus by Wnt5a and Frizzled-8 is independent of the canonical Wnt pathway. Int J Dev Biol (2001) 1.42
Drosophila tissue polarity requires the cell-autonomous activity of the fuzzy gene, which encodes a novel transmembrane protein. Development (1997) 1.37
The function of the frizzled pathway in the Drosophila wing is dependent on inturned and fuzzy. Genetics (2002) 1.37
Inturned localizes to the proximal side of wing cells under the instruction of upstream planar polarity proteins. Curr Biol (2004) 1.32
The Drosophila tissue polarity gene inturned acts cell autonomously and encodes a novel protein. Development (1996) 1.28
Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse. Dev Dyn (2009) 1.28
The WD40 repeat protein fritz links cytoskeletal planar polarity to frizzled subcellular localization in the Drosophila epidermis. Genetics (2005) 1.15
Control of vertebrate intraflagellar transport by the planar cell polarity effector Fuz. J Cell Biol (2012) 1.11
Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol (2013) 1.09
Insights into the molecular evolution of the PDZ/LIM family and identification of a novel conserved protein motif. PLoS One (2007) 1.09
The multiple-wing-hairs gene encodes a novel GBD-FH3 domain-containing protein that functions both prior to and after wing hair initiation. Genetics (2008) 1.08
Planar polarity genes in the Drosophila wing regulate the localisation of the FH3-domain protein Multiple Wing Hairs to control the site of hair production. Development (2008) 1.06
Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. Hum Mol Genet (2011) 1.04
Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes. Dev Cell (2013) 0.99
The PCP effector Fuzzy controls cilial assembly and signaling by recruiting Rab8 and Dishevelled to the primary cilium. Mol Biol Cell (2013) 0.95
Responses of hair follicle-associated structures to loss of planar cell polarity signaling. Proc Natl Acad Sci U S A (2013) 0.93
Planar cell polarity pathway regulates nephrin endocytosis in developing podocytes. J Biol Chem (2013) 0.93
Fuz regulates craniofacial development through tissue specific responses to signaling factors. PLoS One (2011) 0.90
PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube. Dev Dyn (2011) 0.89
Wnt and planar cell polarity signaling in cystic renal disease. Organogenesis (2013) 0.86
The Drosophila planar polarity proteins inturned and multiple wing hairs interact physically and function together. Genetics (2010) 0.83