Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant.

PubWeight™: 0.77‹?›

🔗 View Article (PMC 4239810)

Published in Mamm Genome on August 05, 2014

Authors

Youming Zhang1, Charlotte Dean, Lauren Chessum, Dao Nguyen, Michelle Stewart, Martin Taylor, William O Cookson, Miriam F Moffatt

Author Affiliations

1: Molecular Genetics and Genomics Group, Division of Respiratory Sciences, National Heart and Lung Institute, Imperial College London, Dovehouse Street, London, SW3 6LY, UK, y.zhang@imperial.ac.uk.

Articles cited by this

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol (1986) 35.41

Pfam: multiple sequence alignments and HMM-profiles of protein domains. Nucleic Acids Res (1998) 8.87

Interleukin-2: inception, impact, and implications. Science (1988) 8.19

Zinc finger proteins: new insights into structural and functional diversity. Curr Opin Struct Biol (2001) 4.92

A genome-wide search for quantitative trait loci underlying asthma. Nature (1996) 3.58

The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol (2003) 3.22

Interleukin-2 induction of T-cell G1 progression and c-myb expression. Science (1986) 2.26

Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. Nat Genet (2003) 2.21

NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions. Clin Microbiol Rev (2002) 1.97

A gene-driven approach to the identification of ENU mutants in the mouse. Nat Genet (2002) 1.76

Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradation. Mol Cell Biol (2006) 1.76

Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nat Genet (1995) 1.70

Polymorphisms of PHF11 and DPP10 are associated with asthma and related traits in a Chinese population. Respiration (2009) 1.48

A missense mutation in the zinc-finger domain of the human hairless gene underlies congenital atrichia in a family of Irish travellers. Am J Hum Genet (1998) 1.32

Comprehensive testing of positionally cloned asthma genes in two populations. Am J Respir Crit Care Med (2007) 1.32

Estimating the number of coding mutations in genotypic- and phenotypic-driven N-ethyl-N-nitrosourea (ENU) screens. Mamm Genome (2006) 1.24

Genetic and genomic approaches to asthma: new insights for the origins. Curr Opin Pulm Med (2012) 1.17

Elevated serum interferon-gamma in atopic asthma correlates with increased airways responsiveness and circadian peak expiratory flow variation. Eur Respir J (1998) 1.12

The zinc finger mutation C417R of I-kappa B kinase gamma impairs lipopolysaccharide- and TNF-mediated NF-kappa B activation through inhibiting phosphorylation of the I-kappa B kinase beta activation loop. J Immunol (2004) 1.04

CLLD8/KMT1F is a lysine methyltransferase that is important for chromosome segregation. J Biol Chem (2010) 1.00

A genome-wide screen for asthma-associated quantitative trait loci in a mouse model of allergic asthma. Hum Mol Genet (1999) 0.93

Mutagenesis strategies for identifying novel loci associated with disease phenotypes. Semin Cell Dev Biol (2003) 0.92

Polymorphisms within the PHF11 gene at chromosome 13q14 are associated with childhood atopic dermatitis. Genes Immun (2005) 0.91

Functional characterization of the atopy-associated gene PHF11. J Allergy Clin Immunol (2008) 0.90

Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1). J Allergy Clin Immunol (2011) 0.84

ENU mutagenesis as a tool for understanding lung development and disease. Biochem Soc Trans (2009) 0.81

Articles by these authors

Merlin--rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet (2001) 53.16

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08

A genome-wide association study of global gene expression. Nat Genet (2007) 22.98

Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat Genet (2006) 9.87

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94

Disordered microbial communities in asthmatic airways. PLoS One (2010) 6.35

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses. BMC Biol (2014) 4.39

Variants of DENND1B associated with asthma in children. N Engl J Med (2009) 4.18

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet (2009) 3.41

A high-morbidity outbreak of methicillin-resistant Staphylococcus aureus among players on a college football team, facilitated by cosmetic body shaving and turf burns. Clin Infect Dis (2004) 3.29

Genetic and environmental effects on complex traits in mice. Genetics (2006) 3.27

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nat Genet (2013) 3.17

The influence of Hispanic ethnicity on nonsmall cell lung cancer histology and patient survival: an analysis of the Survival, Epidemiology, and End Results database. Cancer (2012) 3.12

Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib. Cancer Discov (2014) 2.79

Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77

A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol (2009) 2.53

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet (2010) 2.43

Outgrowth of the bacterial airway microbiome after rhinovirus exacerbation of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 2.28

Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. Nat Genet (2003) 2.21

The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2014) 2.17

Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB J (2013) 2.16

Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet (2003) 2.16

Significance of the microbiome in obstructive lung disease. Thorax (2012) 1.97

A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice. Mamm Genome (2006) 1.96

Evaluation of functionally meaningful measures for clinical trials of cognition enhancement in schizophrenia. Am J Psychiatry (2011) 1.86

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease. Hum Mol Genet (2005) 1.81

A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines. Genome Res (2013) 1.72

NOD1 variation, immunoglobulin E and asthma. Hum Mol Genet (2005) 1.66

Improved detection of bifidobacteria with optimised 16S rRNA-gene based pyrosequencing. PLoS One (2012) 1.62

Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors. Genome Res (2012) 1.60

Filaggrin mutations in children with severe atopic dermatitis. J Invest Dermatol (2007) 1.46

The genetics of atopic dermatitis. J Allergy Clin Immunol (2006) 1.39

Gene-environment interaction for childhood asthma and exposure to farming in Central Europe. J Allergy Clin Immunol (2011) 1.30

Gene-environment interactions in chronic inflammatory disease. Nat Immunol (2011) 1.30

Do racial or socioeconomic disparities exist in lung cancer treatment? Cancer (2010) 1.25

Gene-associated markers provide tools for tackling illegal fishing and false eco-certification. Nat Commun (2012) 1.20

Genome-wide association study of lung function decline in adults with and without asthma. J Allergy Clin Immunol (2012) 1.20

Conditions associated with the cystic fibrosis defect promote chronic Pseudomonas aeruginosa infection. Am J Respir Crit Care Med (2014) 1.19

Development of the egg hatch assay for detection of anthelminthic resistance in human hookworms. Int J Parasitol (2005) 1.18

Genetic and genomic approaches to asthma: new insights for the origins. Curr Opin Pulm Med (2012) 1.17

Upper airways microbiota in antibiotic-naïve wheezing and healthy infants from the tropics of rural Ecuador. PLoS One (2012) 1.17

The origin, global distribution, and functional impact of the human 8p23 inversion polymorphism. Genome Res (2012) 1.14

Genetic and perinatal risk factors for asthma onset and severity: a review and theoretical analysis. Epidemiol Rev (2002) 1.14

Treatment of chronic steroid-refractory graft-versus-host disease with low-dose rituximab. Transplantation (2008) 1.09

Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics (2009) 1.08

Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma. Front Genet (2013) 1.08

Dynamic and physical clustering of gene expression during epidermal barrier formation in differentiating keratinocytes. PLoS One (2009) 1.08

Establishing normal plasma and 24-hour urinary biochemistry ranges in C3H, BALB/c and C57BL/6J mice following acclimatization in metabolic cages. Lab Anim (2010) 1.07

Synthesis and cytotoxicity of epoxide and pyrazole analogs of the combretastatins. Bioorg Med Chem (2005) 1.07

Mapping the spawning grounds of North Sea cod (Gadus morhua) by direct and indirect means. Proc Biol Sci (2008) 1.06

Connective tissue structure of the tree shrew optic nerve and associated ageing changes. Invest Ophthalmol Vis Sci (2007) 1.03

Competing functions encoded in the allergy-associated F(c)epsilonRIbeta gene. Immunity (2003) 1.02

Sequencing the human microbiome in health and disease. Hum Mol Genet (2013) 1.02

Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung. Dev Biol (2012) 1.01

Multichange isothermal mutagenesis: a new strategy for multiple site-directed mutations in plasmid DNA. ACS Synth Biol (2013) 1.01

The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled. Dev Biol (2012) 1.00

The stringent response controls catalases in Pseudomonas aeruginosa and is required for hydrogen peroxide and antibiotic tolerance. J Bacteriol (2013) 0.99

Integrating pathway analysis and genetics of gene expression for genome-wide association study of basal cell carcinoma. Hum Genet (2011) 0.99

Evaluation of the efficacy of pyrantel-oxantel for the treatment of soil-transmitted nematode infections. Trans R Soc Trop Med Hyg (2003) 0.98

Predicting DNA methylation level across human tissues. Nucleic Acids Res (2014) 0.98

Clinical trials of potential cognitive-enhancing drugs in schizophrenia: what have we learned so far? Schizophr Bull (2011) 0.97

Chromosome 17q21 SNP and severe asthma. J Hum Genet (2010) 0.96

Genome-wide association studies in the genetics of asthma. Curr Allergy Asthma Rep (2009) 0.95

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis. Hum Mol Genet (2013) 0.95

Dispersal of Mycobacterium tuberculosis via the Canadian fur trade. Proc Natl Acad Sci U S A (2011) 0.95

Adolescent opiate exposure in the female rat induces subtle alterations in maternal care and transgenerational effects on play behavior. Front Psychiatry (2011) 0.95

The genetics of atopic dermatitis. Curr Opin Allergy Clin Immunol (2002) 0.94

Demographic characteristics and employment among people with severe mental illness in a multisite study. Community Ment Health J (2006) 0.90

Impact of collection and storage of lung tumor tissue on whole genome expression profiling. J Mol Diagn (2012) 0.88

Urethral obstruction by seminal coagulum is associated with medetomidine-ketamine anesthesia in male mice on C57BL/6J and mixed genetic backgrounds. J Am Assoc Lab Anim Sci (2009) 0.88

Diversity of Mycobacterium tuberculosis isolates in an immigrant population: evidence against a founder effect. Am J Epidemiol (2004) 0.87

Genetics of complex airway disease. Proc Am Thorac Soc (2011) 0.87

The stringent response modulates 4-hydroxy-2-alkylquinoline biosynthesis and quorum-sensing hierarchy in Pseudomonas aeruginosa. J Bacteriol (2014) 0.87

α-Synuclein levels modulate Huntington's disease in mice. Hum Mol Genet (2011) 0.86

The level of p38α mitogen-activated protein kinase activation in airway epithelial cells determines the onset of innate immune responses to planktonic and biofilm Pseudomonas aeruginosa. J Infect Dis (2013) 0.86

A plant-produced H1N1 trimeric hemagglutinin protects mice from a lethal influenza virus challenge. Hum Vaccin Immunother (2013) 0.86

Gene-environment interaction in chronic disease: a European Science Foundation Forward Look. J Allergy Clin Immunol (2011) 0.85

Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1). J Allergy Clin Immunol (2011) 0.84

Initial validity and reliability data on the Columbia-Suicide Severity Rating Scale. Am J Psychiatry (2012) 0.83

The International Health Partnership Plus: rhetoric or real change? Results of a self-reported survey in the context of the 4th High Level Forum on Aid Effectiveness in Busan. Global Health (2012) 0.83

LD mapping of maternally and non-maternally derived alleles and atopy in FcepsilonRI-beta. Hum Mol Genet (2003) 0.83

Mucoid Pseudomonas aeruginosa caused by mucA mutations result in activation of TLR2 in addition to TLR5 in airway epithelial cells. Biochem Biophys Res Commun (2012) 0.82

ENU mutagenesis as a tool for understanding lung development and disease. Biochem Soc Trans (2009) 0.81

A molecular comparison of microbial communities in bronchiectasis and cystic fibrosis. Eur Respir J (2013) 0.81

An unusual case of tracheoesophageal fistulae. Case Rep Med (2012) 0.81

Investigation of the chromosome 17q25 PSORS2 locus in atopic dermatitis. J Invest Dermatol (2006) 0.80

An influenza N1 neuraminidase-specific monoclonal antibody with broad neuraminidase inhibition activity against H5N1 HPAI viruses. Hum Vaccin (2011) 0.80

The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers. BMC Med Genet (2011) 0.79

Autotransfusion of shed mediastinal blood: a risk factor for mediastinitis after cardiac surgery? Results of a cluster investigation. Chest (2003) 0.79