Published in Am J Respir Crit Care Med on August 16, 2007
Assessing the reproducibility of asthma candidate gene associations, using genome-wide data. Am J Respir Crit Care Med (2009) 2.10
Genome-wide analysis of survival in early-stage non-small-cell lung cancer. J Clin Oncol (2009) 1.52
Sex-stratified linkage analysis identifies a female-specific locus for IgE to cockroach in Costa Ricans. Am J Respir Crit Care Med (2008) 1.43
Asthma and ethnic minorities: socioeconomic status and beyond. Curr Opin Allergy Clin Immunol (2009) 1.38
Ozone, oxidant defense genes, and risk of asthma during adolescence. Am J Respir Crit Care Med (2007) 1.33
Genetic variations in GRIA1 on chromosome 5q33 related to asparaginase hypersensitivity. Clin Pharmacol Ther (2010) 1.15
Race, ethnicity and social class and the complex etiologies of asthma. Pharmacogenomics (2008) 1.09
Genome Wide Association Study to predict severe asthma exacerbations in children using random forests classifiers. BMC Med Genet (2011) 1.04
Neuropeptide S receptor induces neuropeptide expression and associates with intermediate phenotypes of functional gastrointestinal disorders. Gastroenterology (2009) 0.99
Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema. Am J Respir Cell Mol Biol (2009) 0.98
Role of ADAM and ADAMTS metalloproteinases in airway diseases. Respir Res (2009) 0.95
Thymic stromal lymphopoietin (TSLP) is associated with allergic rhinitis in children with asthma. Clin Mol Allergy (2011) 0.92
The clinical implications of mouse models of enhanced anxiety. Future Neurol (2011) 0.89
Genes to diseases (G2D) computational method to identify asthma candidate genes. PLoS One (2008) 0.86
A genome-wide association scan for asthma in a general Australian population. Hum Genet (2008) 0.85
DNA methylation in the Neuropeptide S Receptor 1 (NPSR1) promoter in relation to asthma and environmental factors. PLoS One (2013) 0.84
Genome-wide interaction study identifies RCBTB1 as a modifier for smoking effect on carotid intima-media thickness. Arterioscler Thromb Vasc Biol (2013) 0.83
Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1). PLoS One (2011) 0.83
Interaction between retinoid acid receptor-related orphan receptor alpha (RORA) and neuropeptide S receptor 1 (NPSR1) in asthma. PLoS One (2013) 0.82
Investigating highly replicated asthma genes as candidate genes for allergic rhinitis. BMC Med Genet (2013) 0.82
Genetic variation of ITGB3 is associated with asthma in Chinese Han children. PLoS One (2013) 0.81
The asthma candidate gene NPSR1 mediates isoform specific downstream signalling. BMC Pulm Med (2011) 0.80
Risk factors for allergic rhinitis in Costa Rican children with asthma. Allergy (2009) 0.80
The role of neuropeptide S and neuropeptide S receptor 1 in regulation of respiratory function in mice. Peptides (2010) 0.79
Analyses of associations between three positionally cloned asthma candidate genes and asthma or asthma-related phenotypes in a Chinese population. BMC Med Genet (2009) 0.78
Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant. Mamm Genome (2014) 0.77
Neuropeptide S receptor 1 (NPSR1) activates cancer-related pathways and is widely expressed in neuroendocrine tumors. Virchows Arch (2014) 0.75
A functional AT/G polymorphism in the 5'-untranslated region of SETDB2 in the IgE locus on human chromosome 13q14. Genes Immun (2015) 0.75
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
The International HapMap Project. Nature (2003) 73.65
The structure of haplotype blocks in the human genome. Science (2002) 50.88
A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature (2007) 35.08
Efficiency and power in genetic association studies. Nat Genet (2005) 25.56
PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet (1998) 23.25
A comprehensive review of genetic association studies. Genet Med (2002) 16.75
Replication validity of genetic association studies. Nat Genet (2001) 16.30
A tutorial on statistical methods for population association studies. Nat Rev Genet (2006) 12.49
Long-term effects of budesonide or nedocromil in children with asthma. The Childhood Asthma Management Program Research Group. N Engl J Med (2000) 8.32
Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature (2002) 8.28
Problems of reporting genetic associations with complex outcomes. Lancet (2003) 8.11
Using linkage genome scans to improve power of association in genome scans. Am J Hum Genet (2006) 5.67
The Childhood Asthma Management Program (CAMP): design, rationale, and methods. Childhood Asthma Management Program Research Group. Control Clin Trials (1999) 5.11
Transferability of tag SNPs in genetic association studies in multiple populations. Nat Genet (2006) 4.78
No gene is an island: the flip-flop phenomenon. Am J Hum Genet (2007) 4.69
PBAT: tools for family-based association studies. Am J Hum Genet (2004) 4.68
Characterization of a common susceptibility locus for asthma-related traits. Science (2004) 4.05
A genome-wide search for quantitative trait loci underlying asthma. Nature (1996) 3.58
Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nat Genet (2006) 3.54
Analysis of dose-response curves to methacholine. An approach suitable for population studies. Am Rev Respir Dis (1987) 3.03
Freely associating. Nat Genet (1999) 2.91
Once and again-issues surrounding replication in genetic association studies. J Clin Endocrinol Metab (2002) 2.35
Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. Nat Genet (2003) 2.21
Asthma is associated with single-nucleotide polymorphisms in ADAM33. Clin Exp Allergy (2004) 2.20
Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet (2003) 2.16
Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am J Hum Genet (2004) 2.03
The portability of tagSNPs across populations: a worldwide survey. Genome Res (2006) 1.99
G-Protein-coupled receptor polymorphisms are associated with asthma in a large German population. Am J Respir Crit Care Med (2005) 1.88
Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica. J Allergy Clin Immunol (2007) 1.88
"Are we there yet?": Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits. Am J Hum Genet (2003) 1.82
Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma. Am J Respir Crit Care Med (2005) 1.78
Genetic demography of Antioquia (Colombia) and the Central Valley of Costa Rica. Hum Genet (2003) 1.76
Contribution of ADAM33 polymorphisms to the population risk of asthma. Thorax (2005) 1.76
Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations. J Allergy Clin Immunol (2003) 1.69
Distribution of IgE in a community population sample: correlations with age, sex, and allergen skin test reactivity. J Allergy Clin Immunol (1981) 1.54
ADAM33 is not associated with asthma in Puerto Rican or Mexican populations. Am J Respir Crit Care Med (2003) 1.47
ADAM33 polymorphisms and phenotype associations in childhood asthma. J Allergy Clin Immunol (2004) 1.43
ADAM33 polymorphism: association with bronchial hyper-responsiveness in Korean asthmatics. Clin Exp Allergy (2004) 1.41
Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function. Am J Respir Crit Care Med (2005) 1.40
Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood. J Allergy Clin Immunol (2007) 1.29
ADAM33 polymorphisms are associated with asthma susceptibility in a Japanese population. Clin Exp Allergy (2006) 1.16
Evaluating HapMap SNP data transferability in a large-scale genotyping project involving 175 cancer-associated genes. Hum Genet (2005) 1.13
Summary health statistics for U.S. children: National Health Interview Survey, 2004. Vital Health Stat 10 (2006) 1.11
G protein-coupled receptor 154 gene polymorphism is associated with airway hyperresponsiveness to methacholine in a Chinese population. J Allergy Clin Immunol (2006) 1.09
The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations. Respir Res (2006) 1.04
Chromosome 7p linkage and GPR154 gene association in Italian families with allergic asthma. Clin Exp Allergy (2007) 1.03
Asthma. JAMA (1997) 1.02
Association between ADAM33 polymorphisms and adult asthma in the Japanese population. Clin Exp Allergy (2006) 1.01
Positional identification of an asthma susceptibility gene on human chromosome 5q33. Am J Respir Crit Care Med (2005) 1.00
ADAM33 haplotypes are associated with asthma in a large Australian population. Eur J Hum Genet (2006) 0.97
Lack of association between ADAM33 gene and asthma in a Chinese population. Int J Immunogenet (2006) 0.95
The importance of genetic influences in asthma. Eur Respir J (1999) 0.95
Regression to the truth: replication of association in pharmacogenetic studies. Pharmacogenomics (2003) 0.83
Lack of association of GPRA (G protein-coupled receptor for asthma susceptibility) haplotypes with high serum IgE or asthma in a Korean population. J Allergy Clin Immunol (2004) 0.80
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest (2006) 8.43
Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol (2004) 5.57
Genomic screening and replication using the same data set in family-based association testing. Nat Genet (2005) 5.44
Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet (2004) 5.01
PBAT: tools for family-based association studies. Am J Hum Genet (2004) 4.68
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet (2008) 4.66
Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica. Am J Respir Crit Care Med (2009) 4.64
Family-based designs in the age of large-scale gene-association studies. Nat Rev Genet (2006) 4.59
Family-based association between Alzheimer's disease and variants in UBQLN1. N Engl J Med (2005) 4.34
Worldwide severity and control of asthma in children and adults: the global asthma insights and reality surveys. J Allergy Clin Immunol (2004) 4.17
Is vitamin D deficiency to blame for the asthma epidemic? J Allergy Clin Immunol (2007) 3.97
MMP12, lung function, and COPD in high-risk populations. N Engl J Med (2009) 3.96
Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr (2007) 3.89
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med (2011) 3.80
A genome-wide association study of pulmonary function measures in the Framingham Heart Study. PLoS Genet (2009) 3.78
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. J Allergy Clin Immunol (2010) 3.54
A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics (2003) 3.52
Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet (2010) 3.44
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet (2009) 3.41
Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr (2007) 3.40
On the replication of genetic associations: timing can be everything! Am J Hum Genet (2008) 3.32
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24
A new testing strategy to identify rare variants with either risk or protective effect on disease. PLoS Genet (2011) 3.13
Rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage enzyme-linked immunospot. Am J Respir Crit Care Med (2006) 3.12
Genetic model testing and statistical power in population-based association studies of quantitative traits. Genet Epidemiol (2007) 2.95
Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. Am J Respir Crit Care Med (2004) 2.62
Airway responsiveness in mild to moderate childhood asthma: sex influences on the natural history. Am J Respir Crit Care Med (2008) 2.61
Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. Am J Hum Genet (2009) 2.56
A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol (2009) 2.53
Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. Am J Med Genet B Neuropsychiatr Genet (2008) 2.53
Estimating the number of unseen variants in the human genome. Proc Natl Acad Sci U S A (2009) 2.47
The SERPINE2 gene is associated with chronic obstructive pulmonary disease. Am J Hum Genet (2005) 2.46
Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan. Am J Hum Genet (2007) 2.45
Uric acid and the development of hypertension: the normative aging study. Hypertension (2006) 2.45
Obesity and asthma. Am J Respir Crit Care Med (2006) 2.43
Genome-wide association scan of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet (2008) 2.40
Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma. Am J Respir Crit Care Med (2003) 2.39
Statin exposure is associated with decreased asthma-related emergency department visits and oral corticosteroid use. Am J Respir Crit Care Med (2013) 2.36
The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet (2007) 2.35
The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. Blood (2006) 2.33
Minimal haplotype tagging. Proc Natl Acad Sci U S A (2003) 2.28
Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children. PLoS Genet (2009) 2.27
Association of vitamin D receptor gene polymorphisms with childhood and adult asthma. Am J Respir Crit Care Med (2004) 2.24
Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease. Am J Hum Genet (2002) 2.23
Prediction of chronic obstructive pulmonary disease (COPD) in asthma patients using electronic medical records. J Am Med Inform Assoc (2009) 2.20
The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Hum Mol Genet (2004) 2.19
Using the noninformative families in family-based association tests: a powerful new testing strategy. Am J Hum Genet (2003) 2.18
Cytokines, allergy, and asthma. Curr Opin Allergy Clin Immunol (2005) 2.16
Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. Nat Genet (2012) 2.15
A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects. Stat Appl Genet Mol Biol (2004) 2.15
Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. Hum Mol Genet (2004) 2.14
Chronic caregiver stress and IgE expression, allergen-induced proliferation, and cytokine profiles in a birth cohort predisposed to atopy. J Allergy Clin Immunol (2004) 2.11