Published in Hum Genet on September 02, 2014
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Global cancer statistics, 2002. CA Cancer J Clin (2005) 119.22
An integrated map of genetic variation from 1,092 human genomes. Nature (2012) 59.82
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
Genetic analysis of genome-wide variation in human gene expression. Nature (2004) 27.28
Population genomics of human gene expression. Nat Genet (2007) 24.49
Mapping the genetic architecture of gene expression in human liver. PLoS Biol (2008) 19.44
Genome-wide associations of gene expression variation in humans. PLoS Genet (2005) 17.27
Mapping determinants of human gene expression by regional and genome-wide association. Nature (2005) 17.24
Lung cancer. N Engl J Med (2008) 13.49
Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer (1953) 11.45
Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol (2008) 11.05
High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet (2008) 9.68
Genetics and beyond--the transcriptome of human monocytes and disease susceptibility. PLoS One (2010) 7.48
Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat Genet (2013) 7.13
Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet (2012) 6.97
A navigator for human genome epidemiology. Nat Genet (2008) 5.07
Effects of cigarette smoke on the human airway epithelial cell transcriptome. Proc Natl Acad Sci U S A (2004) 4.89
Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat Med (2007) 4.63
p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis. Cancer Cell (2003) 2.65
A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection. Cell (2013) 2.60
Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer. J Natl Cancer Inst (1999) 2.34
Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis. J Clin Invest (1997) 2.30
iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53. Nat Genet (2006) 2.20
The TP53 gene, tobacco exposure, and lung cancer. Hum Mutat (2003) 1.86
Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis. Cell Death Differ (2012) 1.81
Identification of polymorphic antioxidant response elements in the human genome. Hum Mol Genet (2007) 1.79
The field of tissue injury in the lung and airway. Cancer Prev Res (Phila) (2008) 1.77
A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines. Genome Res (2013) 1.72
Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation. Proc Natl Acad Sci U S A (2005) 1.49
Molecular epidemiology of lung cancer. Ann Oncol (1999) 1.48
Signatures of environmental exposures using peripheral leukocyte gene expression: tobacco smoke. Cancer Epidemiol Biomarkers Prev (2004) 1.44
Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts. PLoS Genet (2009) 1.17
Human single-nucleotide polymorphisms alter p53 sequence-specific binding at gene regulatory elements. Nucleic Acids Res (2010) 1.03
Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer. PLoS One (2010) 1.02
Real-time gap ligase chain reaction: a rapid semiquantitative assay for detecting p53 mutation at low levels in surgical margins and lymph nodes from resected lung and head and neck tumors. Clin Cancer Res (2004) 0.90
Effects of cigarette smoke on the human airway epithelial cell transcriptome. Proc Natl Acad Sci U S A (2004) 4.89
450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. Environ Health Perspect (2012) 4.89
Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat Med (2007) 4.63
Automatic clustering of orthologs and inparalogs shared by multiple proteomes. Bioinformatics (2006) 3.98
Plasma soluble urokinase receptor levels are increased but do not distinguish primary from secondary focal segmental glomerulosclerosis. Kidney Int (2013) 3.97
Anatase TiO2 single crystals with a large percentage of reactive facets. Nature (2008) 3.66
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. Nature (2013) 3.22
Predictive factors for glaucomatous visual field progression in the Advanced Glaucoma Intervention Study. Ophthalmology (2004) 3.14
Caribbean corals in crisis: record thermal stress, bleaching, and mortality in 2005. PLoS One (2010) 2.69
A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection. Cell (2013) 2.60
Prednisone in Uric Acid lowering in Symptomatic Heart Failure Patients With Hyperuricemia (PUSH-PATH) study. Can J Cardiol (2013) 2.60
Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners. Nat Cell Biol (2006) 2.52
Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells. Breast Cancer Res Treat (2007) 2.49
Gene expression in lung adenocarcinomas of smokers and nonsmokers. Am J Respir Cell Mol Biol (2003) 2.45
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A (2009) 2.37
Gene expression profiling of human lung tissue from smokers with severe emphysema. Am J Respir Cell Mol Biol (2004) 2.33
TLR4 links podocytes with the innate immune system to mediate glomerular injury. J Am Soc Nephrol (2008) 2.23
Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression. Genome Biol (2007) 2.20
NAT2 slow acetylation and bladder cancer in workers exposed to benzidine. Int J Cancer (2006) 2.16
Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2008) 2.15
The structure of ferrihydrite, a nanocrystalline material. Science (2007) 2.11
Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium. BMC Genomics (2008) 2.11
Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha. Nucleic Acids Res (2012) 2.07
Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion. Cancer Res (2007) 2.02
Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts. J Cell Sci (2005) 1.95
State of the art. Chronic obstructive pulmonary disease, inflammation, and lung cancer. Proc Am Thorac Soc (2006) 1.92
Airway PI3K pathway activation is an early and reversible event in lung cancer development. Sci Transl Med (2010) 1.84
Re-evaluation of the histopathologic classification of ANCA-associated glomerulonephritis: a study of 121 patients in a single center. Nephrol Dial Transplant (2011) 1.82
Identification of polymorphic antioxidant response elements in the human genome. Hum Mol Genet (2007) 1.79
The field of tissue injury in the lung and airway. Cancer Prev Res (Phila) (2008) 1.77
Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury. Am J Respir Crit Care Med (2009) 1.77
HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin. Am J Physiol Cell Physiol (2010) 1.75
A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. Am J Respir Crit Care Med (2013) 1.73
Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review. Am J Epidemiol (2002) 1.73
Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis. Cancer Res (2011) 1.71
Identification of a microRNA signature in renal fibrosis: role of miR-21. Am J Physiol Renal Physiol (2011) 1.70
Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity. Hum Mol Genet (2005) 1.69
Surface-engineered magnetic nanoparticle platforms for cancer imaging and therapy. Acc Chem Res (2011) 1.69
Noncanonical DNA motifs as transactivation targets by wild type and mutant p53. PLoS Genet (2008) 1.67
Relationship of DNA methylation and gene expression in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2014) 1.63
Expression-based discovery of variation in the human glutathione S-transferase M3 promoter and functional analysis in a glioma cell line using allele-specific chromatin immunoprecipitation. Cancer Res (2005) 1.62
Participation of the urokinase receptor in neutrophil efferocytosis. Blood (2009) 1.62
Potential role of high-mobility group box 1 in cystic fibrosis airway disease. Am J Respir Crit Care Med (2008) 1.62
Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq. Cancer Prev Res (Phila) (2011) 1.61
Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury. Am J Respir Crit Care Med (2008) 1.61
Ligand-dependent scope and divergent mechanistic behavior in nickel-catalyzed reductive couplings of aldehydes and alkynes. J Am Chem Soc (2004) 1.59
A highly homozygous and parthenogenetic human embryonic stem cell line derived from a one-pronuclear oocyte following in vitro fertilization procedure. Cell Res (2007) 1.58
Association of Interferon- and transforming growth factor β-regulated genes and macrophage activation with systemic sclerosis-related progressive lung fibrosis. Arthritis Rheumatol (2014) 1.58
Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: current and developing technologies. Mutat Res (2008) 1.56
Pooled analysis of alcohol dehydrogenase genotypes and head and neck cancer: a HuGE review. Am J Epidemiol (2004) 1.56
The renal histopathological spectrum of patients with nephrotic syndrome: an analysis of 1523 patients in a single Chinese centre. Nephrol Dial Transplant (2011) 1.54
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis (2010) 1.54
Targeted disruption of MCPIP1/Zc3h12a results in fatal inflammatory disease. Immunol Cell Biol (2013) 1.53
Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases. Nature (2016) 1.52
miR-129 regulates cell proliferation by downregulating Cdk6 expression. Cell Cycle (2010) 1.51
Pathologic predictors of renal outcome and therapeutic efficacy in IgA nephropathy: validation of the oxford classification. Clin J Am Soc Nephrol (2011) 1.51
Functional magnetic resonance imaging activation of the brain in children: real acupoint versus sham acupoint. J Child Neurol (2010) 1.51
Effect of acupuncture on the brain in children with spastic cerebral palsy using functional neuroimaging (FMRI). J Child Neurol (2008) 1.51
Surveillance of macrolide-resistant Mycoplasma pneumoniae in Beijing, China, from 2008 to 2012. Antimicrob Agents Chemother (2012) 1.51
Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation. Proc Natl Acad Sci U S A (2005) 1.49
Divergent evolution of human p53 binding sites: cell cycle versus apoptosis. PLoS Genet (2007) 1.47
Efficient synthesis and properties of isomeric photochromic diarylethenes having a pyrrole unit. Org Lett (2007) 1.46
Plasmon resonance enhanced multicolour photodetection by graphene. Nat Commun (2011) 1.45
Solvothermal synthesis and photoreactivity of anatase TiO(2) nanosheets with dominant {001} facets. J Am Chem Soc (2009) 1.45
Isolation and characterization of fourteen novel putative and nine known target genes of the p53 family. Cancer Biol Ther (2003) 1.45
Study of stone composition changes in melamine-related urinary calculi and its clinical significance. Urology (2011) 1.44
Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer Res (2010) 1.44
Participation of miR-200 in pulmonary fibrosis. Am J Pathol (2011) 1.43
Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis. J Clin Immunol (2008) 1.42
Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium. Physiol Genomics (2009) 1.42
Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations. Cancer Res (2008) 1.41
Depression recognition using resting-state and event-related fMRI signals. Magn Reson Imaging (2012) 1.41
On the true photoreactivity order of {001}, {010}, and {101} facets of anatase TiO2 crystals. Angew Chem Int Ed Engl (2011) 1.41
A prediction model for lung cancer diagnosis that integrates genomic and clinical features. Cancer Prev Res (Phila) (2008) 1.41
Comparing clines on molecular and phenotypic traits in hybrid zones: a window on tension zone models. Evolution (2008) 1.39
Complement deposition in renal histopathology of patients with ANCA-associated pauci-immune glomerulonephritis. Nephrol Dial Transplant (2008) 1.37
Clinicopathological characteristics and outcomes of patients with crescentic lupus nephritis. Kidney Int (2009) 1.37
Clinical characteristics of the autumn-winter type scrub typhus cases in south of Shandong province, northern China. BMC Infect Dis (2009) 1.36
Fibroblast growth factor 2 promotes endothelial differentiation of adipose tissue-derived stem cells. J Sex Med (2008) 1.35
KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol (2008) 1.33
Tubulointerstitial lesions of patients with lupus nephritis classified by the 2003 International Society of Nephrology and Renal Pathology Society system. Kidney Int (2010) 1.32
Assessment of the gene expression profile of differentiated and dedifferentiated human fetal chondrocytes by microarray analysis. Arthritis Rheum (2002) 1.32
Interaction between PLA2R1 and HLA-DQA1 variants associates with anti-PLA2R antibodies and membranous nephropathy. J Am Soc Nephrol (2013) 1.31
XPD codon 751 polymorphism, metabolism genes, smoking, and bladder cancer risk. Cancer Epidemiol Biomarkers Prev (2002) 1.31
Amorphous TiO(2) nanotube arrays for low-temperature oxygen sensors. Nanotechnology (2008) 1.30
miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling. Am J Physiol Lung Cell Mol Physiol (2012) 1.29
SIEGE: Smoking Induced Epithelial Gene Expression Database. Nucleic Acids Res (2005) 1.29
Genetic polymorphisms in GSTM1, -P1, -T1, and CYP2E1 and the risk of adult brain tumors. Cancer Epidemiol Biomarkers Prev (2003) 1.28
PAI-1 inhibits neutrophil efferocytosis. Proc Natl Acad Sci U S A (2008) 1.27