Published in N Engl J Med on November 05, 2014
The Use of TKM-100802 and Convalescent Plasma in 2 Patients With Ebola Virus Disease in the United States. Clin Infect Dis (2015) 3.83
Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea. PLoS Med (2016) 2.88
The Contribution of Ebola Viral Load at Admission and Other Patient Characteristics to Mortality in a Médecins Sans Frontières Ebola Case Management Centre, Kailahun, Sierra Leone, June-October 2014. J Infect Dis (2015) 2.64
Ebola virus disease. BMJ (2014) 2.63
Ebola virus disease among children in West Africa. N Engl J Med (2015) 2.17
Ethical and practical considerations in providing critical care to patients with Ebola virus disease. Chest (2015) 2.05
Early clinical sequelae of Ebola virus disease in Sierra Leone: a cross-sectional study. Lancet Infect Dis (2015) 1.94
Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014. Viruses (2014) 1.73
Evaluating large-scale blood transfusion therapy for the current Ebola epidemic in Liberia. J Infect Dis (2015) 1.56
Characteristics and Clinical Management of a Cluster of 3 Patients With Ebola Virus Disease, Including the First Domestically Acquired Cases in the United States. Ann Intern Med (2015) 1.47
Ethics review of studies during public health emergencies - the experience of the WHO ethics review committee during the Ebola virus disease epidemic. BMC Med Ethics (2017) 1.39
Interferon β-1a for the treatment of Ebola virus disease: A historically controlled, single-arm proof-of-concept trial. PLoS One (2017) 1.39
Use of Viremia to Evaluate the Baseline Case Fatality Ratio of Ebola Virus Disease and Inform Treatment Studies: A Retrospective Cohort Study. PLoS Med (2015) 1.32
Ebola Virus Disease Complicated by Late-Onset Encephalitis and Polyarthritis, Sierra Leone. Emerg Infect Dis (2016) 1.31
Delayed Disease Progression in Cynomolgus Macaques Infected with Ebola Virus Makona Strain. Emerg Infect Dis (2015) 1.31
Buffer AVL Alone Does Not Inactivate Ebola Virus in a Representative Clinical Sample Type. J Clin Microbiol (2015) 1.24
Clinical characteristics of 154 patients suspected of having Ebola virus disease in the Ebola holding center of Jui Government Hospital in Sierra Leone during the 2014 Ebola outbreak. Eur J Clin Microbiol Infect Dis (2015) 1.22
Personal Protective Equipment: Protecting Health Care Providers in an Ebola Outbreak. Clin Ther (2015) 1.16
Clinical Management of Ebola Virus Disease in the United States and Europe. N Engl J Med (2016) 1.15
Ebola Virus Outbreak Investigation, Sierra Leone, September 28-November 11, 2014. Emerg Infect Dis (2015) 1.10
Differential diagnosis of illness in travelers arriving from Sierra Leone, Liberia, or Guinea: a cross-sectional study from the GeoSentinel Surveillance Network. Ann Intern Med (2015) 1.06
Gastrointestinal and Hepatic Manifestations of Ebola Virus Infection. Dig Dis Sci (2015) 1.06
Blood kinetics of Ebola virus in survivors and nonsurvivors. J Clin Invest (2015) 1.04
Ebola virus vaccine trials: the ethical mandate for a therapeutic safety net. BMJ (2014) 1.04
Field Evaluation of Capillary Blood Samples as a Collection Specimen for the Rapid Diagnosis of Ebola Virus Infection During an Outbreak Emergency. Clin Infect Dis (2015) 1.01
Ebola vaccine development plan: ethics, concerns and proposed measures. BMC Med Ethics (2016) 0.98
Ebola: a holistic approach is required to achieve effective management and control. J Allergy Clin Immunol (2015) 0.92
Prognostic Analysis of Patients with Ebola Virus Disease. PLoS Negl Trop Dis (2015) 0.92
Towards detection and diagnosis of Ebola virus disease at point-of-care. Biosens Bioelectron (2015) 0.91
Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial. PLoS Med (2016) 0.91
Ebola virus disease and Marburg disease in pregnancy: a review and management considerations for filovirus infection. Obstet Gynecol (2015) 0.89
Critical Care for Multiple Organ Failure Secondary to Ebola Virus Disease in the United States. Crit Care Med (2015) 0.88
Experimental Treatment of Ebola Virus Disease with Brincidofovir. PLoS One (2016) 0.88
Presence and Persistence of Ebola or Marburg Virus in Patients and Survivors: A Rapid Systematic Review. PLoS Negl Trop Dis (2016) 0.88
Personal Protective Equipment for Filovirus Epidemics: A Call for Better Evidence. J Infect Dis (2015) 0.87
Clinical Features of and Risk Factors for Fatal Ebola Virus Disease, Moyamba District, Sierra Leone, December 2014-February 2015. Emerg Infect Dis (2016) 0.86
Feasibility of Xpert Ebola Assay in Médecins Sans Frontières Ebola Program, Guinea. Emerg Infect Dis (2016) 0.86
Successful Implementation of a Multicountry Clinical Surveillance and Data Collection System for Ebola Virus Disease in West Africa: Findings and Lessons Learned. Glob Health Sci Pract (2016) 0.84
The face of Ebola: changing frequency of haemorrhage in the West African compared with Eastern-Central African outbreaks. BMC Infect Dis (2015) 0.84
The etiology of Ebola virus disease-like illnesses in Ebola virusnegative patients from Sierra Leone. Oncotarget (2016) 0.83
Association of clinical signs and symptoms of Ebola viral disease with case fatality: a systematic review and meta-analysis. J Community Hosp Intern Med Perspect (2015) 0.83
Ebola Virus Infection: Overview and Update on Prevention and Treatment. Infect Dis Ther (2015) 0.83
Ebola virus disease and critical illness. Crit Care (2016) 0.82
FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga. J Infect Dis (2016) 0.81
Ebola Virus Disease, Democratic Republic of the Congo, 2014. Emerg Infect Dis (2016) 0.81
Ebola virus disease: What clinicians in the United States need to know. Am J Infect Control (2015) 0.81
Ebola Virus Disease in Children, Sierra Leone, 2014-2015. Emerg Infect Dis (2016) 0.81
Epidemiology of Epidemic Ebola Virus Disease in Conakry and Surrounding Prefectures, Guinea, 2014-2015. Emerg Infect Dis (2016) 0.80
Factors Underlying Ebola Virus Infection Among Health Workers, Kenema, Sierra Leone, 2014-2015. Clin Infect Dis (2016) 0.79
Assessing the direct effects of the ebola outbreak on life expectancy in liberia, sierra leone and Guinea. PLoS Curr (2015) 0.79
Plasmodium Parasitemia Associated With Increased Survival in Ebola Virus-Infected Patients. Clin Infect Dis (2016) 0.79
Heterogeneities in the case fatality ratio in the West African Ebola outbreak 2013-2016. Philos Trans R Soc Lond B Biol Sci (2017) 0.79
Strengthening Health Systems While Responding to a Health Crisis: Lessons Learned by a Nongovernmental Organization During the Ebola Virus Disease Epidemic in Sierra Leone. J Infect Dis (2016) 0.79
Neglected filoviruses. FEMS Microbiol Rev (2016) 0.78
Ebola response in Sierra Leone: The impact on children. J Infect (2016) 0.78
Transforming Clinical Data into Actionable Prognosis Models: Machine-Learning Framework and Field-Deployable App to Predict Outcome of Ebola Patients. PLoS Negl Trop Dis (2016) 0.78
Aetiology of PCR negative suspected Crimean-Congo hemorrhagic fever cases in an endemic area. Pathog Glob Health (2016) 0.75
Chinese Public Attention to the Outbreak of Ebola in West Africa: Evidence from the Online Big Data Platform. Int J Environ Res Public Health (2016) 0.75
Understanding bleeding in ebola virus disease. Clin Adv Hematol Oncol (2015) 0.75
Development of a Prediction Model for Ebola Virus Disease: A Retrospective Study in Nzérékoré Ebola Treatment Center, Guinea. Am J Trop Med Hyg (2016) 0.75
Systems biology: A tool for charting the antiviral landscape. Virus Res (2016) 0.75
Predicting Ebola Severity: A Clinical Prioritization Score for Ebola Virus Disease. PLoS Negl Trop Dis (2017) 0.75
Clinical presentations and outcomes of patients with Ebola virus disease in Freetown, Sierra Leone. Infect Dis Poverty (2016) 0.75
Aerial medical evacuation of health workers with suspected Ebola virus disease in Guinea Conakry-interest of a negative pressure isolation pod-a case series. BMC Emerg Med (2017) 0.75
The Individualised versus the Public Health Approach to Treating Ebola. PLoS Med (2015) 0.75
Clinical, virological, and biological parameters associated with outcomes of Ebola virus infection in Macenta, Guinea. JCI Insight (2017) 0.75
Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings. PLoS Negl Trop Dis (2016) 0.75
Development and Implementation of the Ebola Traveler Monitoring Program and Clinical Outcomes of Monitored Travelers during October - May 2015, Minnesota. PLoS One (2016) 0.75
Ultrasensitive Detection of Bacteria by Targeting Abundant Transcripts. Sci Rep (2016) 0.75
Emergence of Ebola virus disease in a french acute care setting: a simulation study based on documented inter-individual contacts. Sci Rep (2016) 0.75
Analysis of Diagnostic Findings From the European Mobile Laboratory in Guéckédou, Guinea, March 2014 Through March 2015. J Infect Dis (2016) 0.75
A Health Care Worker with Ebola Virus Disease and Adverse Prognostic Factors Treated in Sierra Leone. Am J Trop Med Hyg (2016) 0.75
Ebola virus disease and the veterinary perspective. Ann Clin Microbiol Antimicrob (2015) 0.75
Caring for Critically Ill Ebola Virus Disease Patients With One Hand Tied Behind Your Back. Crit Care Med (2015) 0.75
Electrolyte and Metabolic Disturbances in Ebola Patients during a Clinical Trial, Guinea, 2015. Emerg Infect Dis (2016) 0.75
Predicting Subnational Ebola Virus Disease Epidemic Dynamics from Sociodemographic Indicators. PLoS One (2016) 0.75
Predicting Ebola infection: A malaria-sensitive triage score for Ebola virus disease. PLoS Negl Trop Dis (2017) 0.75
Spatial and temporal dynamics of superspreading events in the 2014-2015 West Africa Ebola epidemic. Proc Natl Acad Sci U S A (2017) 0.75
Preparing for Serious Communicable Diseases in the United States: What the Ebola Virus Epidemic Has Taught Us. Microbiol Spectr (2016) 0.75
Influence of Referral Pathway on Ebola Virus Disease Case-Fatality Rate and Effect of Survival Selection Bias. Emerg Infect Dis (2017) 0.75
Validation of a portable, deployable system for continuous vital sign monitoring using a multiparametric wearable sensor and personalised analytics in an Ebola treatment centre. BMJ Glob Health (2016) 0.75
Operational Research during the Ebola Emergency. Emerg Infect Dis (2017) 0.75
The natural history of acute Ebola virus disease among patients managed in five Ebola treatment units in West Africa: A retrospective cohort study. PLoS Negl Trop Dis (2017) 0.75
Emerging Infectious Diseases: Epidemiological Perspective. Indian J Dermatol (2017) 0.75
The predictor of mortality outcome in adult patients with Ebola virus disease during the 2014-2015 outbreak in Guinea. Eur J Clin Microbiol Infect Dis (2016) 0.75
Mortality among PCR negative admitted Ebola suspects during the 2014/15 outbreak in Conakry, Guinea: A retrospective cohort study. PLoS One (2017) 0.75
Ebola Virus Delta Peptide is a Viroporin. J Virol (2017) 0.75
Emergence of Zaire Ebola virus disease in Guinea. N Engl J Med (2014) 16.45
Critically ill patients with 2009 influenza A(H1N1) infection in Canada. JAMA (2009) 13.00
Update on avian influenza A (H5N1) virus infection in humans. N Engl J Med (2008) 10.27
Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N Engl J Med (2010) 9.90
Critically Ill patients with 2009 influenza A(H1N1) in Mexico. JAMA (2009) 9.41
Zika virus, French polynesia, South pacific, 2013. Emerg Infect Dis (2014) 6.75
High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med (2013) 6.56
Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea. N Engl J Med (2016) 6.22
Eligibility criteria of randomized controlled trials published in high-impact general medical journals: a systematic sampling review. JAMA (2007) 6.09
Rapid diagnosis of Ebola hemorrhagic fever by reverse transcription-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome. J Virol (2004) 5.86
Critical care and the global burden of critical illness in adults. Lancet (2010) 5.55
Effect of selective decontamination on antimicrobial resistance in intensive care units: a systematic review and meta-analysis. Lancet Infect Dis (2013) 5.37
The international Ebola emergency. N Engl J Med (2014) 5.35
Clinical illness and outcomes in patients with Ebola in Sierra Leone. N Engl J Med (2014) 5.17
Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review. Am J Respir Crit Care Med (2008) 5.06
Failure to engage hospitalized elderly patients and their families in advance care planning. JAMA Intern Med (2013) 3.77
Ebola virus disease in West Africa--clinical manifestations and management. N Engl J Med (2014) 3.73
One-step RT-PCR for detection of Zika virus. J Clin Virol (2008) 3.41
Marburg hemorrhagic fever associated with multiple genetic lineages of virus. N Engl J Med (2006) 3.38
Studies of reservoir hosts for Marburg virus. Emerg Infect Dis (2007) 3.35
A multifaceted intervention for quality improvement in a network of intensive care units: a cluster randomized trial. JAMA (2011) 3.08
Patient and healthcare professional factors influencing end-of-life decision-making during critical illness: a systematic review. Crit Care Med (2011) 3.07
Traveler's diarrhea in Thailand: randomized, double-blind trial comparing single-dose and 3-day azithromycin-based regimens with a 3-day levofloxacin regimen. Clin Infect Dis (2006) 3.05
Caring for critically ill patients with ebola virus disease. Perspectives from West Africa. Am J Respir Crit Care Med (2014) 2.90
Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid. J Clin Epidemiol (2011) 2.69
Basic clinical and laboratory features of filoviral hemorrhagic fever. J Infect Dis (2011) 2.52
Hantavirus in African wood mouse, Guinea. Emerg Infect Dis (2006) 2.49
Surviving sepsis in low-income and middle-income countries: new directions for care and research. Lancet Infect Dis (2009) 2.47
New opportunities for field research on the pathogenesis and treatment of Lassa fever. Antiviral Res (2007) 2.47
Novel hantavirus sequences in Shrew, Guinea. Emerg Infect Dis (2007) 2.44
Worldwide emergence of multiple clades of enterovirus 68. J Gen Virol (2012) 2.35
Seasonal influenza epidemiology in sub-Saharan Africa: a systematic review. Lancet Infect Dis (2011) 2.29
Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies. J Am Acad Dermatol (2008) 2.29
Quantitative real-time PCR detection of Zika virus and evaluation with field-caught mosquitoes. Virol J (2013) 2.28
Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal. Malar J (2007) 2.26
Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes. Chest (2013) 2.24
Blood chemistry measurements and D-Dimer levels associated with fatal and nonfatal outcomes in humans infected with Sudan Ebola virus. J Infect Dis (2007) 2.22
A prospective, observational registry of patients with severe sepsis: the Canadian Sepsis Treatment and Response Registry. Crit Care Med (2009) 2.17
Ebola virus disease among children in West Africa. N Engl J Med (2015) 2.17
Failure of anticoagulant thromboprophylaxis: risk factors in medical-surgical critically ill patients*. Crit Care Med (2015) 2.16
Integrating mortality and morbidity outcomes: using quality-adjusted life years in critical care trials. Am J Respir Crit Care Med (2012) 2.15
Critical illness in children with influenza A/pH1N1 2009 infection in Canada. Pediatr Crit Care Med (2010) 2.08
Reducing time-to-treatment decreases mortality of trauma patients with acute subdural hematoma. Ann Surg (2011) 2.06
Evolutionary history and dynamics of dog rabies virus in western and central Africa. J Gen Virol (2009) 1.98
Retracted Resistance to DDT and pyrethroids and increased kdr mutation frequency in An. gambiae after the implementation of permethrin-treated nets in Senegal. PLoS One (2012) 1.97
Mastomys natalensis and Lassa fever, West Africa. Emerg Infect Dis (2006) 1.94
Is a mass immunization program for pandemic (H1N1) 2009 good value for money? Evidence from the Canadian Experience. Vaccine (2010) 1.91
Sex-and age-based differences in the delivery and outcomes of critical care. CMAJ (2007) 1.91
Potential impact on estimated treatment effects of information lost to follow-up in randomised controlled trials (LOST-IT): systematic review. BMJ (2012) 1.85
Prospects for immunisation against Marburg and Ebola viruses. Rev Med Virol (2010) 1.77
The critically ill child with novel H1N1 influenza A: a case series. Pediatr Crit Care Med (2010) 1.77
Randomized trial of piperaquine with sulfadoxine-pyrimethamine or dihydroartemisinin for malaria intermittent preventive treatment in children. PLoS One (2009) 1.73
Clinical characteristics of a series of 302 French patients with hidradenitis suppurativa, with an analysis of factors associated with disease severity. J Am Acad Dermatol (2009) 1.68
Morbidity and survival probability in burn patients in modern burn care. Crit Care Med (2015) 1.67
Crimean-Congo hemorrhagic fever, Mauritania. Emerg Infect Dis (2004) 1.65
Hypoglycemia at admission is associated with inhospital mortality in Ugandan patients with severe sepsis. Crit Care Med (2011) 1.64
Access to urban acute care services in high- vs. middle-income countries: an analysis of seven cities. Intensive Care Med (2013) 1.64
Knowledge translation in critical care: factors associated with prescription of commonly recommended best practices for critically ill patients. Crit Care Med (2007) 1.62
Screening and prevention of venous thromboembolism in critically ill patients: a decision analysis and economic evaluation. Am J Respir Crit Care Med (2011) 1.58
Hypoglycemia is associated with increased postburn morbidity and mortality in pediatric patients. Crit Care Med (2014) 1.58
Evolutionary processes among sylvatic dengue type 2 viruses. J Virol (2007) 1.54
The use of a mobile laboratory unit in support of patient management and epidemiological surveillance during the 2005 Marburg Outbreak in Angola. PLoS Negl Trop Dis (2011) 1.53
Knowledge translation interventions for critically ill patients: a systematic review*. Crit Care Med (2013) 1.53
Clinical research during a public health emergency: a systematic review of severe pandemic influenza management. Crit Care Med (2013) 1.51
Nighttime cross-coverage is associated with decreased intensive care unit mortality. A single-center study. Am J Respir Crit Care Med (2014) 1.50
Vector competence of Aedes aegypti populations from Senegal for sylvatic and epidemic dengue 2 virus isolated in West Africa. Trans R Soc Trop Med Hyg (2008) 1.50
A triple-blinded randomized trial comparing the hemostatic effects of large-dose 10% hydroxyethyl starch 264/0.45 versus 5% albumin during major reconstructive surgery. Anesth Analg (2005) 1.49
Audit and feedback to reduce broad-spectrum antibiotic use among intensive care unit patients: a controlled interrupted time series analysis. Infect Control Hosp Epidemiol (2012) 1.49
Entomologic investigations of a chikungunya virus epidemic in the Union of the Comoros, 2005. Am J Trop Med Hyg (2008) 1.48
Point-of-care lactate testing predicts mortality of severe sepsis in a predominantly HIV type 1-infected patient population in Uganda. Clin Infect Dis (2008) 1.48
Inconsistent definitions for intention-to-treat in relation to missing outcome data: systematic review of the methods literature. PLoS One (2012) 1.48
Open source clinical science for emerging infections. Lancet Infect Dis (2014) 1.47
The highs and lows of intensive insulin therapy. Am J Respir Crit Care Med (2006) 1.47
Nonbeneficial treatment Canada: definitions, causes, and potential solutions from the perspective of healthcare practitioners*. Crit Care Med (2015) 1.45
A seasonal model to simulate influenza oscillation in Tokyo. Jpn J Infect Dis (2003) 1.45
Marburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatment. J Infect Dis (2007) 1.44
Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients. Crit Care Med (2016) 1.44
Doing today's work superbly well--treating Ebola with current tools. N Engl J Med (2014) 1.43