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PCNA, the maestro of the replication fork. Cell (2007) 10.43

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A base-excision DNA-repair protein finds intrahelical lesion bases by fast sliding in contact with DNA. Proc Natl Acad Sci U S A (2006) 4.60

An oxygen scavenging system for improvement of dye stability in single-molecule fluorescence experiments. Biophys J (2007) 4.49

Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism. Proc Natl Acad Sci U S A (1999) 4.05

Repetitive shuttling of a motor protein on DNA. Nature (2005) 3.82

Single-molecule kinetics of lambda exonuclease reveal base dependence and dynamic disorder. Science (2003) 3.22

Single-molecule imaging of RNA polymerase-DNA interactions in real time. Biophys J (1999) 3.03

Single molecule measurements of repressor protein 1D diffusion on DNA. Phys Rev Lett (2006) 2.81

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SSB protein diffusion on single-stranded DNA stimulates RecA filament formation. Nature (2009) 2.33

XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer. Nat Genet (2005) 2.26

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Sliding and jumping of single EcoRV restriction enzymes on non-cognate DNA. Nucleic Acids Res (2008) 1.86

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Single-stranded DNA scanning and deamination by APOBEC3G cytidine deaminase at single molecule resolution. J Biol Chem (2012) 1.30

Single-molecule approaches to characterizing kinetics of biomolecular interactions. Curr Opin Biotechnol (2010) 1.25

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The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scattering. J Mol Biol (1998) 1.12

An archaeal endonuclease displays key properties of both eukaryal XPF-ERCC1 and Mus81. J Biol Chem (2004) 1.10

Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threading. J Biol Chem (2010) 1.09

Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer. Genome Integr (2012) 1.00

Sequential and multistep substrate interrogation provides the scaffold for specificity in human flap endonuclease 1. Cell Rep (2013) 0.96

Single-molecule characterization of Fen1 and Fen1/PCNA complexes acting on flap substrates. Nucleic Acids Res (2013) 0.94

Single-molecule conformational dynamics of fluctuating noncovalent DNA-protein interactions in DNA damage recognition. J Am Chem Soc (2001) 0.92

Structure and function of a novel endonuclease acting on branched DNA substrates. EMBO J (2009) 0.89

The enzyme mechanism of nitrite reductase studied at single-molecule level. Proc Natl Acad Sci U S A (2008) 0.86

Modulation of the Pyrococcus abyssi NucS endonuclease activity by replication clamp at functional and structural levels. J Biol Chem (2012) 0.85

Single-molecule fluorescence polarization study of conformational change in archaeal group II chaperonin. PLoS One (2011) 0.83

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EMSA and single-molecule force spectroscopy study of interactions between Bacillus subtilis single-stranded DNA-binding protein and single-stranded DNA. Langmuir (2011) 0.79