Published in Angew Chem Int Ed Engl on December 04, 2014
HaloTag technology: a versatile platform for biomedical applications. Bioconjug Chem (2015) 0.80
Sugar-dependent modulation of neuronal development, regeneration, and plasticity by chondroitin sulfate proteoglycans. Exp Neurol (2015) 0.79
Quantitative investigation of human cell surface N-glycoprotein dynamics. Chem Sci (2016) 0.77
Nanoscale materials for probing the biological functions of the glycocalyx. Glycobiology (2016) 0.75
Glycan Engineering for Cell and Developmental Biology. Cell Chem Biol (2016) 0.75
Advances in cell surface glycoengineering reveal biological function. Glycobiology (2016) 0.75
Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med (2001) 9.51
Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature (2002) 6.51
HaloTag: a novel protein labeling technology for cell imaging and protein analysis. ACS Chem Biol (2008) 6.00
Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Mol Cell (2000) 5.72
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. Development (2007) 5.62
Direct reprogramming of mouse fibroblasts to neural progenitors. Proc Natl Acad Sci U S A (2011) 3.93
Functions of heparan sulfate proteoglycans in cell signaling during development. Development (2004) 3.56
Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells (2005) 3.38
A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification. Development (2007) 2.92
Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nat Med (2008) 2.80
Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation. Cell (1994) 2.61
The role of FGF/Erk signaling in pluripotent cells. Development (2010) 2.40
Regeneration next: toward heart stem cell therapeutics. Cell Stem Cell (2009) 1.92
Sequence analysis of heparan sulfate epitopes with graded affinities for fibroblast growth factors 1 and 2. J Biol Chem (2001) 1.68
Preparation and properties of fluorescent polysaccharides. Anal Biochem (1983) 1.48
Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes. J Am Chem Soc (2008) 1.41
6-O-sulfation of heparan sulfate differentially regulates various fibroblast growth factor-dependent signalings in culture. J Biol Chem (2008) 1.22
Glycocalyx remodeling with proteoglycan mimetics promotes neural specification in embryonic stem cells. J Am Chem Soc (2014) 1.14
HaloTag protein-mediated specific labeling of living cells with quantum dots. Biochem Biophys Res Commun (2008) 1.10
Heparan sulfate is required for embryonic stem cells to exit from self-renewal. J Biol Chem (2009) 1.09
Directing neuronal signaling through cell-surface glycan engineering. J Am Chem Soc (2014) 1.03
Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells. J Biol Chem (2012) 1.03
Specific glycosaminoglycans modulate neural specification of mouse embryonic stem cells. Stem Cells (2011) 1.03
Elucidating glycosaminoglycan-protein-protein interactions using carbohydrate microarray and computational approaches. Proc Natl Acad Sci U S A (2011) 1.00
Development of a multiplex autoantibody test for detection of lung cancer. PLoS One (2014) 0.91
Glycosaminoglycans as regulators of stem cell differentiation. Biochem Soc Trans (2011) 0.90
Undersulfation of heparan sulfate restricts differentiation potential of mouse embryonic stem cells. J Biol Chem (2012) 0.88
A hexylchloride-based catch-and-release system for chemical proteomic applications. ACS Chem Biol (2013) 0.82
Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics. Nat Chem Biol (2007) 3.60
Phosphofructokinase 1 glycosylation regulates cell growth and metabolism. Science (2012) 3.05
Sulfation patterns of glycosaminoglycans encode molecular recognition and activity. Nat Chem Biol (2006) 2.25
Exploring the O-GlcNAc proteome: direct identification of O-GlcNAc-modified proteins from the brain. Proc Natl Acad Sci U S A (2004) 2.17
A chemoenzymatic approach toward the rapid and sensitive detection of O-GlcNAc posttranslational modifications. J Am Chem Soc (2003) 2.14
Profiling the sulfation specificities of glycosaminoglycan interactions with growth factors and chemotactic proteins using microarrays. Chem Biol (2007) 1.95
Quantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags. Nat Chem Biol (2010) 1.79
Direct in-gel fluorescence detection and cellular imaging of O-GlcNAc-modified proteins. J Am Chem Soc (2008) 1.71
Chemical approaches to understanding O-GlcNAc glycosylation in the brain. Nat Chem Biol (2008) 1.60
Dynamic O-GlcNAc modification regulates CREB-mediated gene expression and memory formation. Nat Chem Biol (2012) 1.52
Parallel identification of O-GlcNAc-modified proteins from cell lysates. J Am Chem Soc (2004) 1.48
Site-specific GlcNAcylation of human erythrocyte proteins: potential biomarker(s) for diabetes. Diabetes (2008) 1.39
Neuroactive chondroitin sulfate glycomimetics. J Am Chem Soc (2008) 1.39
The chemical neurobiology of carbohydrates. Chem Rev (2008) 1.33
A chondroitin sulfate small molecule that stimulates neuronal growth. J Am Chem Soc (2004) 1.21
Chemical approaches to deciphering the glycosaminoglycan code. Curr Opin Chem Biol (2005) 1.19
Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation. J Am Chem Soc (2003) 1.17
Direct identification of nonreducing GlcNAc residues on N-glycans of glycoproteins using a novel chemoenzymatic method. Bioconjug Chem (2007) 1.11
Protein fucosylation regulates synapsin Ia/Ib expression and neuronal morphology in primary hippocampal neurons. Proc Natl Acad Sci U S A (2005) 1.11
Discovery of a TNF-alpha antagonist using chondroitin sulfate microarrays. J Am Chem Soc (2006) 1.08
Spinophilin is phosphorylated by Ca2+/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin. J Neurochem (2004) 1.06
Directing neuronal signaling through cell-surface glycan engineering. J Am Chem Soc (2014) 1.03
A 'molecular switchboard'--covalent modifications to proteins and their impact on transcription. Org Biomol Chem (2003) 1.02
A sulfated carbohydrate epitope inhibits axon regeneration after injury. Proc Natl Acad Sci U S A (2012) 1.00
Elucidating glycosaminoglycan-protein-protein interactions using carbohydrate microarray and computational approaches. Proc Natl Acad Sci U S A (2011) 1.00
End-functionalized glycopolymers as mimetics of chondroitin sulfate proteoglycans. Chem Sci (2010) 0.97
Activation of the transcriptional function of the NF-κB protein c-Rel by O-GlcNAc glycosylation. Sci Signal (2013) 0.97
Tunable heparan sulfate mimetics for modulating chemokine activity. J Am Chem Soc (2013) 0.94
Semaphorin 3A binds to the perineuronal nets via chondroitin sulfate type E motifs in rodent brains. J Biol Chem (2013) 0.93
A role for fucose alpha(1-2) galactose carbohydrates in neuronal growth. J Am Chem Soc (2005) 0.93
Chemoenzymatic probes for detecting and imaging fucose-α(1-2)-galactose glycan biomarkers. J Am Chem Soc (2012) 0.91
The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines. Neuromolecular Med (2002) 0.89
Activation of phospholipase C pathways by a synthetic chondroitin sulfate-E tetrasaccharide promotes neurite outgrowth of dopaminergic neurons. J Neurochem (2007) 0.86
Identification of the plasticity-relevant fucose-alpha(1-2)-galactose proteome from the mouse olfactory bulb. Biochemistry (2009) 0.86
Bioorganic chemistry: a sweet synthesis. Nature (2007) 0.83
Visualization of O-GlcNAc glycosylation stoichiometry and dynamics using resolvable poly(ethylene glycol) mass tags. Curr Protoc Chem Biol (2013) 0.82
Regulation of spinophilin Ser94 phosphorylation in neostriatal neurons involves both DARPP-32-dependent and independent pathways. J Neurochem (2005) 0.81
Tailored glycopolymers as anticoagulant heparin mimetics. Angew Chem Int Ed Engl (2013) 0.80
Molecular recognition and enhancement of aqueous solubility and bioactivity of CD437 by β-cyclodextrin. Bioorg Med Chem Lett (2010) 0.80
Use of cerny epoxides for the accelerated synthesis of glycosaminoglycans. Org Lett (2003) 0.78
Synthetic probes of glycosaminoglycan function. Curr Opin Chem Biol (2013) 0.77
Microarray method for the rapid detection of glycosaminoglycan-protein interactions. Methods Mol Biol (2012) 0.77
Chemistry. Improving biologic drugs via total chemical synthesis. Science (2013) 0.75
Photoactivatable glycopolymers for the proteome-wide identification of fucose-α(1-2)-galactose binding proteins. J Am Chem Soc (2014) 0.75