Published in Cell Stem Cell on October 02, 2009
Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell (2012) 3.66
Bone marrow-derived cell therapy stimulates endogenous cardiomyocyte progenitors and promotes cardiac repair. Cell Stem Cell (2011) 3.49
A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability. PLoS One (2011) 3.39
Role of cardiac stem cells in cardiac pathophysiology: a paradigm shift in human myocardial biology. Circ Res (2011) 2.76
Ex vivo gene transfer and correction for cell-based therapies. Nat Rev Genet (2011) 2.13
In vivo functional and transcriptional profiling of bone marrow stem cells after transplantation into ischemic myocardium. Arterioscler Thromb Vasc Biol (2011) 1.80
Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes. J Mol Cell Cardiol (2011) 1.77
Induction of vascular progenitor cells from endothelial cells stimulates coronary collateral growth. Circ Res (2011) 1.62
Pregenerative medicine: developmental paradigms in the biology of cardiovascular regeneration. J Clin Invest (2010) 1.57
Human pericytes for ischemic heart repair. Stem Cells (2013) 1.39
Bioengineering heart muscle: a paradigm for regenerative medicine. Annu Rev Biomed Eng (2011) 1.26
Fighting fat with fat: the expanding field of adipose stem cells. Cell Stem Cell (2009) 1.25
Cardiovascular molecular imaging: focus on clinical translation. Circulation (2011) 1.24
The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-regulated kinase (ERK)/NRF2 signaling pathway and cytokine release. J Biol Chem (2012) 1.24
Cardiac regeneration. Curr Top Dev Biol (2012) 1.17
Developmental and regenerative biology of multipotent cardiovascular progenitor cells. Circ Res (2011) 1.16
The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation. Am J Physiol Heart Circ Physiol (2012) 1.10
Human myocardial pericytes: multipotent mesodermal precursors exhibiting cardiac specificity. Stem Cells (2015) 1.02
Heart repair and regeneration: recent insights from zebrafish studies. Wound Repair Regen (2012) 1.02
SWI/SNF protein component BAF250a regulates cardiac progenitor cell differentiation by modulating chromatin accessibility during second heart field development. J Biol Chem (2012) 1.01
Computational models reduce complexity and accelerate insight into cardiac signaling networks. Circ Res (2011) 1.00
A complement-IL-4 regulatory circuit controls liver regeneration. J Immunol (2011) 0.99
Comparison of Human Embryonic Stem Cell-Derived Cardiomyocytes, Cardiovascular Progenitors, and Bone Marrow Mononuclear Cells for Cardiac Repair. Stem Cell Reports (2015) 0.93
ATP-sensitive K(+) channel-deficient dilated cardiomyopathy proteome remodeled by embryonic stem cell therapy. Stem Cells (2010) 0.93
Regenerating functional heart tissue for myocardial repair. Cell Mol Life Sci (2012) 0.92
Programming and reprogramming a human heart cell. EMBO J (2015) 0.92
Making it stick: chasing the optimal stem cells for cardiac regeneration. Expert Rev Cardiovasc Ther (2014) 0.91
Lessons for cardiac regeneration and repair through development. Trends Mol Med (2010) 0.89
Current stem cell delivery methods for myocardial repair. Biomed Res Int (2012) 0.89
Innate regeneration in the aging heart: healing from within. Mayo Clin Proc (2013) 0.89
K(ATP) channel-dependent metaboproteome decoded: systems approaches to heart failure prediction, diagnosis, and therapy. Cardiovasc Res (2011) 0.86
Stem cell therapy for inflammatory bowel disease. J Gastroenterol (2015) 0.86
Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells. J Am Heart Assoc (2014) 0.86
Conditioned mesenchymal stem cells produce pleiotropic gut trophic factors. J Gastroenterol (2013) 0.85
Label-free electrophysiological cytometry for stem cell-derived cardiomyocyte clusters. Lab Chip (2012) 0.85
iPSC-derived human mesenchymal stem cells improve myocardial strain of infarcted myocardium. J Cell Mol Med (2014) 0.85
The cardiac hypoxic niche: emerging role of hypoxic microenvironment in cardiac progenitors. Cardiovasc Diagn Ther (2012) 0.83
Response to Bergmann et al: Carbon 14 Birth Dating of Human Cardiomyocytes. Circ Res (2012) 0.82
Bioluminescence imaging: a shining future for cardiac regeneration. J Cell Mol Med (2013) 0.82
Myocardial regeneration of the failing heart. Heart Fail Rev (2013) 0.81
SWI/SNF in cardiac progenitor cell differentiation. J Cell Biochem (2013) 0.81
Promises and pitfalls in cell replacement therapy for heart failure. Drug Discov Today Dis Mech (2010) 0.81
Long-lived engineering of glycans to direct stem cell fate. Angew Chem Int Ed Engl (2014) 0.80
Concise review: skeletal muscle stem cells and cardiac lineage: potential for heart repair. Stem Cells Transl Med (2013) 0.80
Method for obtaining committed adult mesenchymal precursors from skin and lung tissue. PLoS One (2012) 0.79
An early requirement for nkx2.5 ensures the first and second heart field ventricular identity and cardiac function into adulthood. Dev Biol (2014) 0.79
Preconditioning c-Kit-positive Human Cardiac Stem Cells with a Nitric Oxide Donor Enhances Cell Survival through Activation of Survival Signaling Pathways. J Biol Chem (2016) 0.79
Fabp4-CreER lineage tracing reveals two distinctive coronary vascular populations. J Cell Mol Med (2014) 0.78
Derivation of functional ventricular cardiomyocytes using endogenous promoter sequence from murine embryonic stem cells. Stem Cell Res (2011) 0.78
Micromanaging cardiac regeneration: Targeted delivery of microRNAs for cardiac repair and regeneration. World J Cardiol (2016) 0.78
Chronic heart failure: opportunities for a bridge between China and the United States. Circ Res (2013) 0.78
Shedding new light on the mechanism underlying stem cell therapy for the heart. Mol Ther (2011) 0.76
Endpoints in stem cell trials in ischemic heart failure. Stem Cell Res Ther (2015) 0.76
Intracoronary Delivery of Human Mesenchymal/Stromal Stem Cells: Insights from Coronary Microcirculation Invasive Assessment in a Swine Model. PLoS One (2015) 0.76
Tracking stem cells with superparamagnetic iron oxide nanoparticles: perspectives and considerations. Int J Nanomedicine (2017) 0.76
A GPS for heart progenitor cell lineages. Mol Ther (2011) 0.75
Near Equilibrium Calculus of Stem Cells in Application to the Airway Epithelium Lineage. PLoS Comput Biol (2016) 0.75
Cardiomyoblast (h9c2) differentiation on tunable extracellular matrix microenvironment. Tissue Eng Part A (2015) 0.75
Recent Progress on Chemical Biology of Pluripotent Stem Cell Self-renewal, Reprogramming and Cardiomyogenesis. Recent Pat Regen Med (2011) 0.75
Transplantation of multipotent Isl1+ cardiac progenitor cells preserves infarcted heart function in mice. Am J Transl Res (2017) 0.75
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature (2005) 9.44
Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell (2006) 7.21
Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature (2008) 7.03
Marked differences in differentiation propensity among human embryonic stem cell lines. Nat Biotechnol (2008) 6.19
The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Cell (2002) 4.72
Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Nature (2009) 4.68
Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization. Nature (2006) 4.35
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol (2003) 4.25
An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation. Cell (2007) 3.74
Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511. Nat Biotechnol (2010) 3.70
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity. Nat Med (2004) 3.63
Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature (2002) 3.60
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell (2007) 3.54
Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice. Science (2011) 3.49
ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med (2002) 3.36
Epicardial retinoid X receptor alpha is required for myocardial growth and coronary artery formation. Proc Natl Acad Sci U S A (2005) 3.13
Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice. Proc Natl Acad Sci U S A (2002) 3.13
Standardization as a mechanism to improve safety in health care. Jt Comm J Qual Saf (2004) 3.05
Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2. EMBO J (2003) 3.02
Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development (2002) 2.71
Lives of a heart cell: tracing the origins of cardiac progenitors. Cell Stem Cell (2008) 2.68
Generation of functional ventricular heart muscle from mouse ventricular progenitor cells. Science (2009) 2.60
Origins and fates of cardiovascular progenitor cells. Cell (2008) 2.55
BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development (2004) 2.50
Identification of cardiac-specific myosin light chain kinase. Circ Res (2008) 2.45
Islet1 cardiovascular progenitors: a single source for heart lineages? Development (2008) 2.39
Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nat Med (2002) 2.37
Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm. Nat Genet (2012) 2.34
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy. Proc Natl Acad Sci U S A (2002) 2.32
Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function. Mol Cell Biol (2004) 2.12
Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction. Nat Biotechnol (2013) 2.11
p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload. Mol Cell Biol (2004) 1.95
Mouse PeP: a novel peroxisomal protein linked to myoblast differentiation and development. Dev Dyn (2002) 1.87
Tcap gene mutations in hypertrophic cardiomyopathy and dilated cardiomyopathy. J Am Coll Cardiol (2004) 1.79
Stem cells: lost in translation. Nature (2004) 1.79
Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis. J Clin Invest (2004) 1.79
Towards regenerative therapy for cardiac disease. Lancet (2012) 1.75
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene. J Mol Cell Cardiol (2009) 1.72
Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies. Biochem Biophys Res Commun (2004) 1.69
Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo. J Cell Biol (2007) 1.60
Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers. Biotechnol Bioeng (2003) 1.58
Pregenerative medicine: developmental paradigms in the biology of cardiovascular regeneration. J Clin Invest (2010) 1.57
Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells. Circulation (2007) 1.57
Targeted conditional gene knockout in human embryonic stem cells. Cell Res (2010) 1.53
Latent TGF-beta-binding protein 2 binds to DANCE/fibulin-5 and regulates elastic fiber assembly. EMBO J (2007) 1.48
Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling. J Biol Chem (2003) 1.44
Asymmetric septal hypertrophy in heterozygous cMyBP-C null mice. Cardiovasc Res (2004) 1.39
Mixed signals in heart failure: cancer rules. J Clin Invest (2002) 1.36
Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning. Cardiovasc Res (2004) 1.34
Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats. J Clin Invest (2004) 1.33
SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling. J Biol Chem (2003) 1.33
Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. J Clin Invest (2013) 1.32
Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals. J Am Coll Cardiol (2007) 1.29
Bioengineering heart muscle: a paradigm for regenerative medicine. Annu Rev Biomed Eng (2011) 1.26
Reduced cardiac L-type Ca2+ current in Ca(V)beta2-/- embryos impairs cardiac development and contraction with secondary defects in vascular maturation. Circ Res (2006) 1.24
The cardiovascular physiologic actions of urocortin II: acute effects in murine heart failure. Proc Natl Acad Sci U S A (2004) 1.22
Cardiomyopathy associated with microcirculation dysfunction in laminin alpha4 chain-deficient mice. J Biol Chem (2005) 1.22
Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor. J Biol Chem (2002) 1.21
Prox1 maintains muscle structure and growth in the developing heart. Development (2008) 1.21
Small proline-rich protein 1A is a gp130 pathway- and stress-inducible cardioprotective protein. EMBO J (2004) 1.19
Normal fate and altered function of the cardiac neural crest cell lineage in retinoic acid receptor mutant embryos. Mech Dev (2002) 1.18
Comparison of contraction and calcium handling between right and left ventricular myocytes from adult mouse heart: a role for repolarization waveform. J Physiol (2005) 1.17
Perinatal loss of Nkx2-5 results in rapid conduction and contraction defects. Circ Res (2008) 1.16
A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells. Nat Cell Biol (2013) 1.16
Restoration of deficient membrane proteins in the cardiomyopathic hamster by in vivo cardiac gene transfer. Circulation (2002) 1.14
The suppressor of cytokine signaling-1 (SOCS1) is a novel therapeutic target for enterovirus-induced cardiac injury. J Clin Invest (2003) 1.14
Beyond the sarcomere: CSRP3 mutations cause hypertrophic cardiomyopathy. Hum Mol Genet (2008) 1.13
A common MLP (muscle LIM protein) variant is associated with cardiomyopathy. Circ Res (2009) 1.11
Sarcoplasmic reticulum calcium defect in Ras-induced hypertrophic cardiomyopathy heart. Am J Physiol Heart Circ Physiol (2003) 1.11
Calcium and heart failure: the cycle game. Nat Med (2003) 1.09
Ablation of Nkx2-5 at mid-embryonic stage results in premature lethality and cardiac malformation. Cardiovasc Res (2011) 1.08
Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature. Cell Res (2011) 1.08
Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart. Circ Res (2011) 1.07
Slow progressive conduction and contraction defects in loss of Nkx2-5 mice after cardiomyocyte terminal differentiation. Lab Invest (2009) 1.07
Thymosin beta-4 is essential for coronary vessel development and promotes neovascularization via adult epicardium. Ann N Y Acad Sci (2007) 1.04
Stem cell models of cardiac development and disease. Annu Rev Cell Dev Biol (2010) 1.03
Embryonic heart progenitors and cardiogenesis. Cold Spring Harb Perspect Med (2013) 1.01
Reversing advanced heart failure by targeting Ca2+ cycling. Annu Rev Med (2008) 1.01
Reversal of calcium cycling defects in advanced heart failure toward molecular therapy. J Am Coll Cardiol (2006) 0.98
Innate defense mechanism against virus infection within the cardiac myocyte requiring gp130-STAT3 signaling. Circulation (2006) 0.96
Spatial distributions of Kv4 channels and KChip2 isoforms in the murine heart based on laser capture microdissection. Cardiovasc Res (2006) 0.96
Young MLP deficient mice show diastolic dysfunction before the onset of dilated cardiomyopathy. J Mol Cell Cardiol (2005) 0.95
Normal hematopoiesis after conditional targeting of RXRalpha in murine hematopoietic stem/progenitor cells. J Leukoc Biol (2006) 0.93
Distinct roles of HF-1b/Sp4 in ventricular and neural crest cells lineages affect cardiac conduction system development. Dev Biol (2006) 0.92
Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models. Cell Calcium (2009) 0.91
Driving vascular endothelial cell fate of human multipotent Isl1+ heart progenitors with VEGF modified mRNA. Cell Res (2013) 0.90
Molecular medicine: microRNAs and the tell-tale heart. Nature (2007) 0.89
Toward biologically targeted therapy of calcium cycling defects in heart failure. Physiology (Bethesda) (2008) 0.89
Functional differences in engineered myocardium from embryonic stem cell-derived versus neonatal cardiomyocytes. Stem Cell Reports (2013) 0.89
Reprogramming a broken heart. Cell Stem Cell (2012) 0.89
Genetic modifiers of cardiac arrhythmias. Trends Mol Med (2003) 0.89
Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum. J Biol Chem (2004) 0.87
Cardiac origin of smooth muscle cells in the inflow tract. J Mol Cell Cardiol (2010) 0.86
Unravelling Ras signals in cardiovascular disease. Nat Cell Biol (2004) 0.85
LMNA-associated cardiocutaneous progeria: an inherited autosomal dominant premature aging syndrome with late onset. Am J Med Genet A (2013) 0.85
Shortcuts to making cardiomyocytes. Nat Cell Biol (2011) 0.84
The cytoskeleton-associated PDZ-LIM protein, ALP, acts on serum response factor activity to regulate muscle differentiation. Mol Biol Cell (2007) 0.83
Quality: the Mayo Clinic approach. Am J Med Qual (2009) 0.81
Cardiomyocyte reprogramming and the new age of cellular alchemy. J Mol Cell Cardiol (2012) 0.81