Published in RNA Biol on October 31, 2014
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Negative regulation of toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade. Science (2007) 2.18
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Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation. Genes Dev (2011) 2.06
Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli. Mol Cell (2014) 2.05
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The long noncoding RNA RMST interacts with SOX2 to regulate neurogenesis. Mol Cell (2013) 1.48
Mediator complex regulates alternative mRNA processing via the MED23 subunit. Mol Cell (2012) 1.41
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Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. Elife (2014) 1.16
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The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL. Proc Natl Acad Sci U S A (2013) 1.78
The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structure. Proc Natl Acad Sci U S A (2002) 1.46
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Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation. Biochemistry (2002) 1.21
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Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands. J Med Chem (2006) 1.17
Design and creation of new nanomaterials for therapeutic RNAi. ACS Chem Biol (2007) 1.16
A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and iPS cell generation. Nat Commun (2012) 1.14
Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis. Chem Biol Drug Des (2007) 1.12
Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication. J Biol Chem (2003) 1.11
Discovery of nonsteroidal anti-inflammatory drug and anticancer drug enhancing reprogramming and induced pluripotent stem cell generation. Stem Cells (2011) 1.08
Dissecting RNA-interference pathway with small molecules. Chem Biol (2005) 1.07
Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5. Retrovirology (2004) 1.05
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Silencing microRNA by interfering nanoparticles in mice. Nucleic Acids Res (2011) 1.02
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Design and synthesis of HIV-1 protease inhibitors incorporating oxazolidinones as P2/P2' ligands in pseudosymmetric dipeptide isosteres. J Med Chem (2007) 0.97
Selective binding of TAR RNA by a Tat-derived beta-peptide. Org Lett (2003) 0.96
Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression. J Biol Chem (2008) 0.96
Identification of flavopiridol analogues that selectively inhibit positive transcription elongation factor (P-TEFb) and block HIV-1 replication. Chembiochem (2009) 0.95
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Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones. J Med Chem (2010) 0.93
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P-TEFb kinase complex phosphorylates histone H1 to regulate expression of cellular and HIV-1 genes. J Biol Chem (2010) 0.87
Synthesis and structure-activity relationship studies of HIV-1 virion infectivity factor (Vif) inhibitors that block viral replication. ChemMedChem (2012) 0.87
U30 of 7SK RNA forms a specific photo-cross-link with Hexim1 in the context of both a minimal RNA-binding site and a fully reconstituted 7SK/Hexim1/P-TEFb ribonucleoprotein complex. J Mol Biol (2009) 0.86
Molecular mechanisms of RNA-triggered gene silencing machineries. Acc Chem Res (2012) 0.86
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Delivery of therapeutic RNAi by nanovehicles. Chembiochem (2009) 0.85
Substrate envelope-designed potent HIV-1 protease inhibitors to avoid drug resistance. Chem Biol (2013) 0.84
Inhibition of HIV tat-TAR interactions by an antisense oligo-2'-O-methylribonucleoside methylphosphonate. Bioorg Med Chem Lett (2003) 0.84
Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila. Proc Natl Acad Sci U S A (2013) 0.84
miR-TRAP: a benchtop chemical biology strategy to identify microRNA targets. Angew Chem Int Ed Engl (2012) 0.84
Learning the molecular mechanisms of the reprogramming factors: let's start from microRNAs. Mol Biosyst (2012) 0.84
A bimolecular mechanism of HIV-1 Tat protein interaction with RNA polymerase II transcription elongation complexes. J Mol Biol (2002) 0.82
Staged miRNA re-regulation patterns during reprogramming. Genome Biol (2013) 0.82
Efficient Computation of Small-Molecule Configurational Binding Entropy and Free Energy Changes by Ensemble Enumeration. J Chem Theory Comput (2013) 0.82
Testing the substrate-envelope hypothesis with designed pairs of compounds. ACS Chem Biol (2013) 0.81
Using microRNAs to enhance the generation of induced pluripotent stem cells. Curr Protoc Stem Cell Biol (2012) 0.81
Interfering nanoparticles for silencing microRNAs. Methods Enzymol (2012) 0.81
Orientation and affinity of HIV-1 Tat fragments in Tat-TAR complex determined by fluorescence resonance energy transfer. Bioconjug Chem (2006) 0.81
Dynamics of nascent mRNA folding and RNA-protein interactions: an alternative TAR RNA structure is involved in the control of HIV-1 mRNA transcription. Nucleic Acids Res (2006) 0.81
Mechanism of site-specific psoralen photoadducts formation in triplex DNA directed by psoralen-conjugated oligonucleotides. Biochemistry (2005) 0.81
A new class of RNA-binding oligomers: peptoid amide and ester analogues. Bioconjug Chem (2002) 0.79
Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance. J Med Chem (2012) 0.79
Design and synthesis of a novel peptidomimetic inhibitor of HIV-1 Tat-TAR interactions: squaryldiamide as a new potential bioisostere of unsubstituted guanidine. Bioorg Med Chem Lett (2005) 0.78
Design, microwave-assisted synthesis, and photophysical properties of small molecule organic antennas for luminescence resonance energy transfer. J Comb Chem (2005) 0.78
Microwave-assisted parallel synthesis of a 4,6-diamino-2,2-dimethyl-1,2-dihydro-1-phenyl-s-triazine library. J Comb Chem (2004) 0.77
Phosphorylation of histone H1 by P-TEFb is a necessary step in skeletal muscle differentiation. J Cell Physiol (2012) 0.77
In Vivo Delivery of RNAi by Reducible Interfering Nanoparticles (iNOPs). ACS Med Chem Lett (2013) 0.77
Quantitative analysis of RNA-mediated protein-protein interactions in living cells by FRET. Chem Biol Drug Des (2007) 0.75
Design and assembly of new nonviral RNAi delivery agents by microwave-assisted quaternization (MAQ) of tertiary amines. Bioconjug Chem (2010) 0.75
Strategies to antagonize miRNA functions in vitro and in vivo. Nanomedicine (Lond) (2014) 0.75
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