PubRank

Donald K Ingram

Author PubWeight™ 163.92‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006 20.91
2 Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab 2008 6.22
3 Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature 2012 5.00
4 AGEMAP: a gene expression database for aging in mice. PLoS Genet 2007 3.22
5 Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Proc Natl Acad Sci U S A 2003 2.82
6 Metformin improves healthspan and lifespan in mice. Nat Commun 2013 2.68
7 Dietary deprivation extends lifespan in Caenorhabditis elegans. Aging Cell 2006 2.54
8 Calorie restriction in rhesus monkeys. Exp Gerontol 2003 2.52
9 Aging in rhesus monkeys: relevance to human health interventions. Science 2004 2.37
10 Biomarkers of caloric restriction may predict longevity in humans. Science 2002 2.32
11 A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults. Am J Clin Nutr 2007 2.16
12 Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates. Proc Natl Acad Sci U S A 2006 2.03
13 Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans. Aging Cell 2006 2.01
14 Transient improvement in cognitive function and synaptic plasticity in rats following cancer chemotherapy. Clin Cancer Res 2006 1.97
15 Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction. Proc Natl Acad Sci U S A 2008 1.97
16 Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease. Proc Natl Acad Sci U S A 2004 1.86
17 Cognitive impairment following high fat diet consumption is associated with brain inflammation. J Neuroimmunol 2009 1.82
18 Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: contributions of maternal diet. Neurobiol Dis 2009 1.80
19 Involvement of Notch signaling in hippocampal synaptic plasticity. Proc Natl Acad Sci U S A 2004 1.77
20 Age and gender effects on microglia and astrocyte numbers in brains of mice. Brain Res 2002 1.67
21 Circulating adiponectin levels increase in rats on caloric restriction: the potential for insulin sensitization. Exp Gerontol 2004 1.64
22 Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent. Proc Natl Acad Sci U S A 2005 1.61
23 Effects of long-term diet restriction on aging and longevity in primates remain uncertain. J Gerontol A Biol Sci Med Sci 2004 1.60
24 Age-associated learning and memory deficits in two mouse versions of the Stone T-maze. Neurobiol Aging 2012 1.55
25 Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice. Neurobiol Aging 2004 1.46
26 Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging. Cell Metab 2013 1.45
27 Effects of caloric restriction on inflammatory periodontal disease. Nutrition 2008 1.43
28 High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling. J Neurochem 2010 1.43
29 Common physical and functional changes associated with aging in dogs. J Am Vet Med Assoc 2015 1.40
30 Defining healthy aging in older dogs and differentiating healthy aging from disease. J Am Vet Med Assoc 2015 1.40
31 Effect of age and caloric restriction on circadian adrenal steroid rhythms in rhesus macaques. Neurobiol Aging 2007 1.39
32 Caloric restriction and aging in primates: Relevance to humans and possible CR mimetics. Microsc Res Tech 2002 1.30
33 DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking. Alcohol Clin Exp Res 2004 1.23
34 Metformin supplementation and life span in Fischer-344 rats. J Gerontol A Biol Sci Med Sci 2010 1.21
35 Ovarian aging and menopause: current theories, hypotheses, and research models. Exp Biol Med (Maywood) 2005 1.14
36 Impact of reduced meal frequency without caloric restriction on glucose regulation in healthy, normal-weight middle-aged men and women. Metabolism 2007 1.13
37 Dietary restriction in aging nonhuman primates. Interdiscip Top Gerontol 2007 1.12
38 Catecholaminergic neuronal loss in locus coeruleus of aged female dtg APP/PS1 mice. J Chem Neuroanat 2007 1.11
39 Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasion. Circ Res 2009 1.10
40 Age-related decline in caloric intake and motivation for food in rhesus monkeys. Neurobiol Aging 2004 1.10
41 Optimal window of caloric restriction onset limits its beneficial impact on T-cell senescence in primates. Aging Cell 2008 1.09
42 A blueberry-enriched diet provides cellular protection against oxidative stress and reduces a kainate-induced learning impairment in rats. Neurobiol Aging 2007 1.08
43 Adipogenic signaling in rat white adipose tissue: modulation by aging and calorie restriction. Exp Gerontol 2007 1.07
44 Comparative approaches to facilitate the discovery of prolongevity interventions: effects of tocopherols on lifespan of three invertebrate species. Mech Ageing Dev 2006 1.06
45 Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice. Neurosci Lett 2009 1.05
46 Chronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in rats. Toxicol Appl Pharmacol 2009 1.03
47 Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus. Nutr Neurosci 2008 1.02
48 Caloric restriction mimetics: the next phase. Ann N Y Acad Sci 2005 1.02
49 Bioenergetics of aging and calorie restriction. Ageing Res Rev 2006 1.01
50 Caloric restriction mimetics: a novel approach for biogerontology. Methods Mol Biol 2007 1.01
51 Stereological analysis of microvascular parameters in a double transgenic model of Alzheimer's disease. Brain Res Bull 2005 1.00
52 Drusenoid maculopathy in rhesus monkeys (Macaca mulatta): effects of age and gender. Graefes Arch Clin Exp Ophthalmol 2008 0.99
53 Neuropathological quantification of dtg APP/PS1: neuroimaging, stereology, and biochemistry. Age (Dordr) 2007 0.99
54 The prolongevity effect of resveratrol depends on dietary composition and calorie intake in a tephritid fruit fly. Exp Gerontol 2009 0.98
55 In vitro cellular adaptations of indicators of longevity in response to treatment with serum collected from humans on calorie restricted diets. PLoS One 2008 0.97
56 Adiponectin protects rat hippocampal neurons against excitotoxicity. Age (Dordr) 2010 0.97
57 NOX activity in brain aging: exacerbation by high fat diet. Free Radic Biol Med 2010 0.97
58 A blueberry-enriched diet attenuates nephropathy in a rat model of hypertension via reduction in oxidative stress. PLoS One 2011 0.97
59 Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats. Pharmacol Biochem Behav 2004 0.97
60 Prolongevity effects of an oregano and cranberry extract are diet dependent in the Mexican fruit fly (Anastrepha ludens). J Gerontol A Biol Sci Med Sci 2009 0.96
61 Blueberry-enriched diet protects rat heart from ischemic damage. PLoS One 2009 0.96
62 Assessment of auditory function in rhesus monkeys (Macaca mulatta): effects of age and calorie restriction. Neurobiol Aging 2004 0.96
63 Cytokine responses in young and old rhesus monkeys: effect of caloric restriction. J Interferon Cytokine Res 2002 0.94
64 Endometriosis: clinical monitoring and treatment procedures in Rhesus Monkeys. J Med Primatol 2007 0.93
65 Aging of the striatum: mechanisms and interventions. Age (Dordr) 2008 0.93
66 Accelerated cognitive aging in diabetic rats is prevented by lowering corticosterone levels. Neurobiol Learn Mem 2008 0.92
67 The effects of a calorie-reduced diet on periodontal inflammation and disease in a non-human primate model. J Periodontol 2008 0.92
68 Calorie restriction alters physical performance but not cognition in two models of altered neuroendocrine signaling. Behav Brain Res 2008 0.92
69 Striatal lesions interfere with acquisition of a complex maze task in rats. Behav Brain Res 2008 0.91
70 Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice. Antiviral Res 2010 0.91
71 Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition. Psychopharmacology (Berl) 2005 0.91
72 Telomere dynamics in rhesus monkeys: no apparent effect of caloric restriction. J Gerontol A Biol Sci Med Sci 2011 0.90
73 Recording lifetime behavior and movement in an invertebrate model. PLoS One 2011 0.90
74 Chronic caloric restriction partially protects against age-related alteration in serum metabolome. Age (Dordr) 2012 0.90
75 Impact of moderate calorie restriction on testicular morphology and endocrine function in adult rhesus macaques (Macaca mulatta). Age (Dordr) 2013 0.89
76 Effects of moderate calorie restriction on testosterone production and semen characteristics in young rhesus macaques (Macaca mulatta). Biol Reprod 2010 0.88
77 Effects of calorie restriction on reproductive and adrenal systems in Japanese quail: are responses similar to mammals, particularly primates? Mech Ageing Dev 2005 0.88
78 Prolongevity effects of a botanical with oregano and cranberry extracts in Mexican fruit flies: examining interactions of diet restriction and age. Age (Dordr) 2011 0.87
79 Dietary restriction and life-span. Science 2002 0.87
80 Drusenoid maculopathy in rhesus monkeys: autofluorescence, lipofuscin and drusen pathogenesis. Graefes Arch Clin Exp Ophthalmol 2008 0.87
81 Sildenafil citrate attenuates a complex maze impairment induced by intracerebroventricular infusion of the NOS inhibitor Nomega-nitro-L-arginine methyl ester. Eur J Pharmacol 2007 0.86
82 Caloric restriction modulates insulin receptor signaling in liver and skeletal muscle of rat. Nutrition 2005 0.85
83 Manipulation of caloric content but not diet composition, attenuates the deficit in learning and memory of senescence-accelerated mouse strain P8. Exp Gerontol 2008 0.85
84 Relationship between plasma ghrelin, insulin, leptin, interleukin 6, adiponectin, testosterone and longevity in the Baltimore Longitudinal Study of Aging. Aging Clin Exp Res 2011 0.84
85 Age-related decline in striatal volume in rhesus monkeys: assessment of long-term calorie restriction. Neurobiol Aging 2004 0.84
86 Feed efficiency, food choice, and food reward behaviors in young and old Fischer rats. Neurobiol Aging 2010 0.83
87 The effect of caloric restriction on glycation and glycoxidation in skin collagen of nonhuman primates. J Gerontol A Biol Sci Med Sci 2003 0.83
88 A link between maze learning and hippocampal expression of neuroleukin and its receptor gp78. J Neurochem 2002 0.83
89 Effects of phentermine and phenformin on biomarkers of aging in rats. Gerontology 2004 0.83
90 Survival and cardioprotective benefits of long-term blueberry enriched diet in dilated cardiomyopathy following myocardial infarction in rats. PLoS One 2009 0.83
91 Combined administration of subthreshold doses of the nitric oxide inhibitor, nitro-L-arginine, and muscarinic receptor antagonist, scopolamine, impairs complex maze learning in rats. Behav Pharmacol 2007 0.82
92 Neurotherapeutic effects of novel HO-1 inhibitors in vitro and in a transgenic mouse model of Alzheimer's disease. J Neurochem 2014 0.82
93 Nicotine lowers the secretion of the Alzheimer's amyloid beta-protein precursor that contains amyloid beta-peptide in rat. J Alzheimers Dis 2002 0.82
94 Impact of Moderate Calorie Restriction on the Reproductive Neuroendocrine Axis of Male Rhesus Macaques. Open Longev Sci 2010 0.82
95 Red cell interactions with amyloid-beta(1-40) fibrils in a murine model. Neurobiol Dis 2005 0.81
96 Overview of aging research using nonhuman primate models. Age (Dordr) 2012 0.81
97 Effect of caloric restriction on base-excision repair (BER) in the aging rat brain. Exp Gerontol 2009 0.81
98 The serious search for an anti-aging pill. Sci Am 2002 0.81
99 Brain injury caused by HIV protease inhibitors: role of lipodystrophy and insulin resistance. Antiviral Res 2012 0.81
100 Neuroprotection provided by dietary restriction in rats is further enhanced by reducing glucocortocoids. Neurobiol Aging 2012 0.80
101 Loss of taste responds to high-dose biotin treatment. J Am Coll Nutr 2011 0.80
102 17α-estradiol attenuates neuron loss in ovariectomized Dtg AβPP/PS1 mice. J Alzheimers Dis 2011 0.80
103 The interplay among dietary fat, sugar, protein and açai (Euterpe oleracea Mart.) pulp in modulating lifespan and reproduction in a Tephritid fruit fly. Exp Gerontol 2012 0.80
104 Caloric restriction modulates early events in insulin signaling in liver and skeletal muscle of rat. Ann N Y Acad Sci 2004 0.79
105 Nutritional interventions in aging and age-associated diseases. Ann N Y Acad Sci 2007 0.79
106 Effect of calorie restriction and refeeding on skin wound healing in the rat. Age (Dordr) 2011 0.79
107 Blueberries improve glucose tolerance without altering body composition in obese postmenopausal mice. Obesity (Silver Spring) 2015 0.79
108 Dehydroepiandrosterone sulfate (DHEAS) as an endocrine marker of aging in calorie restriction studies. Exp Gerontol 2013 0.79
109 Ovarian reserve tests and their utility in predicting response to controlled ovarian stimulation in rhesus monkeys. Am J Primatol 2010 0.79
110 Pennington scientific symposium on mechanisms and retardation of aging. Exp Gerontol 2003 0.78
111 The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats. Life Sci 2005 0.78
112 Dietary resistant starch improves selected brain and behavioral functions in adult and aged rodents. Mol Nutr Food Res 2013 0.78
113 Natural infection of human adenovirus 36 in rhesus monkeys is associated with a reduction in fasting glucose 36. J Diabetes 2014 0.77
114 In vivo assessment of adenoviral vector-mediated gene expression of dopamine D(2) receptors in the rat striatum by positron emission tomography. Synapse 2002 0.77
115 Passive avoidance and complex maze learning in the senescence accelerated mouse (SAM): age and strain comparisons of SAM P8 and R1. J Gerontol A Biol Sci Med Sci 2002 0.76
116 The Roy Walford legacy: diet restriction from molecules to mice to monkeys to man and onto mimetics. Exp Gerontol 2004 0.76
117 Functional recovery of the striatal cholinergic system in aged rats by adenoviral vector-mediated gene transfer of dopamine D2 receptor. Mech Ageing Dev 2006 0.76
118 Effects of calorie restriction on chromosomal stability in rhesus monkeys (Macaca mulatta). Age (Dordr) 2006 0.76
119 Cholinesterase inhibitors improve both memory and complex learning in aged beagle dogs. J Alzheimers Dis 2011 0.76
120 Preclinical investigation of the topical administration of phenserine: transdermal flux, cholinesterase inhibition, and cognitive efficacy. J Pharmacol Exp Ther 2007 0.76
121 Impaired long-term depression in P2X3 deficient mice is not associated with a spatial learning deficit. J Neurochem 2006 0.75