Published in Pflugers Arch on January 06, 2015
Novel mutations highlight the key role of the ankyrin repeat domain in TRPV4-mediated neuropathy. Neurol Genet (2015) 0.80
Cell migration: integrating signals from front to back. Science (2003) 29.13
Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol (2005) 11.74
TRP channels. Annu Rev Biochem (2007) 8.09
Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nat Rev Mol Cell Biol (2010) 7.27
Focal adhesion motility revealed in stationary fibroblasts. Science (1999) 6.24
Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell (2000) 5.73
Heat-evoked activation of the ion channel, TRPV4. J Neurosci (2002) 4.69
Collective cell guidance by cooperative intercellular forces. Nat Mater (2011) 4.64
Paxillin: adapting to change. Physiol Rev (2004) 4.48
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature (2003) 4.45
Calpain-mediated proteolysis of talin regulates adhesion dynamics. Nat Cell Biol (2004) 4.29
Migration of zebrafish primordial germ cells: a role for myosin contraction and cytoplasmic flow. Dev Cell (2006) 3.39
Ca(2+)- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature (1995) 3.22
Epithelial plasticity: a common theme in embryonic and cancer cells. Science (2013) 3.21
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives. J Biol Chem (2002) 3.14
Calcium flickers steer cell migration. Nature (2008) 3.01
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells. J Biol Chem (2002) 2.87
Calcium in tumour metastasis: new roles for known actors. Nat Rev Cancer (2011) 2.30
Molecular determinants of permeation through the cation channel TRPV4. J Biol Chem (2002) 2.24
The vanilloid transient receptor potential channel TRPV4: from structure to disease. Prog Biophys Mol Biol (2009) 2.13
The switchable integrin adhesome. J Cell Sci (2010) 2.12
A sphingosine-1-phosphate-activated calcium channel controlling vascular smooth muscle cell motility. Circ Res (2006) 2.12
Calcium gradients underlying polarization and chemotaxis of eosinophils. Science (1991) 2.08
Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation. Arterioscler Thromb Vasc Biol (2006) 1.99
Temperature-modulated diversity of TRPV4 channel gating: activation by physical stresses and phorbol ester derivatives through protein kinase C-dependent and -independent pathways. J Biol Chem (2003) 1.97
Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin. Proc Natl Acad Sci U S A (2009) 1.91
Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts. J Biol Chem (2001) 1.91
TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling. Circ Res (2009) 1.84
TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain. J Biol Chem (2006) 1.75
PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4. J Biol Chem (2006) 1.71
TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity. J Cell Biol (2005) 1.68
Role of ion channels and transporters in cell migration. Physiol Rev (2012) 1.52
Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia. J Neurosci (2008) 1.47
Ca2+ influx through L-type Ca2+ channels controls the trailing tail contraction in growth factor-induced fibroblast cell migration. J Biol Chem (2005) 1.36
Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1. J Biol Chem (2009) 1.34
Calpain activity increases in hepatocytes following addition of ATP. Demonstration by a novel fluorescent approach. J Biol Chem (1993) 1.28
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3. J Biol Chem (2008) 1.26
UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling. Proc Natl Acad Sci U S A (2013) 1.26
Functional role of vanilloid transient receptor potential 4-canonical transient receptor potential 1 complex in flow-induced Ca2+ influx. Arterioscler Thromb Vasc Biol (2010) 1.25
TRPC1 regulates skeletal myoblast migration and differentiation. J Cell Sci (2008) 1.25
A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia. Proc Natl Acad Sci U S A (2009) 1.25
Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epithelia. J Biol Chem (2004) 1.22
IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid. J Cell Biol (2008) 1.22
Effects of TRPM8 on the proliferation and motility of prostate cancer PC-3 cells. Asian J Androl (2009) 1.21
Calcium gradients underlying cell migration. Curr Opin Cell Biol (2011) 1.19
Lysophospholipids stimulate prostate cancer cell migration via TRPV2 channel activation. Biochim Biophys Acta (2009) 1.19
Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness. Cancer Res (2009) 1.18
TRPC1 functions as a store-operated Ca2+ channel in intestinal epithelial cells and regulates early mucosal restitution after wounding. Am J Physiol Gastrointest Liver Physiol (2005) 1.18
Elucidation of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement. Mol Biol Cell (2008) 1.17
Forming the cell rear first: breaking cell symmetry to trigger directed cell migration. Nat Cell Biol (2010) 1.16
Bisandrographolide from Andrographis paniculata activates TRPV4 channels. J Biol Chem (2006) 1.14
Importance of melastatin-like transient receptor potential 7 and magnesium in the stimulation of osteoblast proliferation and migration by platelet-derived growth factor. Am J Physiol Cell Physiol (2009) 1.12
The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells. Nat Immunol (2008) 1.10
The TRPV4 channel contributes to intercellular junction formation in keratinocytes. J Biol Chem (2010) 1.07
TRPC1 is essential for in vivo angiogenesis in zebrafish. Circ Res (2010) 1.04
Transient receptor potential canonical channels are essential for chemotactic migration of human malignant gliomas. J Cell Physiol (2011) 1.03
Directional persistence of migrating cells requires Kif1C-mediated stabilization of trailing adhesions. Dev Cell (2012) 1.02
The mechanoreceptor TRPV4 is localized in adherence junctions of the human bladder urothelium: a morphological study. J Urol (2011) 1.01
PSA reduces prostate cancer cell motility by stimulating TRPM8 activity and plasma membrane expression. Oncogene (2010) 1.00
TRPM7 regulates polarized cell movements. Biochem J (2011) 1.00
HGF/SF and menthol increase human glioblastoma cell calcium and migration. Biochem Biophys Res Commun (2008) 1.00
Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli. Proc Natl Acad Sci U S A (2013) 0.99
TRPC1 channels regulate directionality of migrating cells. Pflugers Arch (2008) 0.99
Microtubule-associated [corrected] protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4). J Biol Chem (2003) 0.99
TRPV4 mediates tumor-derived endothelial cell migration via arachidonic acid-activated actin remodeling. Oncogene (2011) 0.99
The role of TMEM16A (ANO1) and TMEM16F (ANO6) in cell migration. Pflugers Arch (2013) 0.98
Involvement of TRPV1 and TRPV4 channels in migration of rat pulmonary arterial smooth muscle cells. Pflugers Arch (2012) 0.96
Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation. Eur J Cell Biol (2008) 0.94
Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localization. J Immunol (2010) 0.94
The calcium-conducting ion channel transient receptor potential canonical 6 is involved in macrophage inflammatory protein-2-induced migration of mouse neutrophils. Acta Physiol (Oxf) (2009) 0.93
TRPM4 regulates migration of mast cells in mice. Cell Calcium (2008) 0.93
CaMK-II promotes focal adhesion turnover and cell motility by inducing tyrosine dephosphorylation of FAK and paxillin. Cell Motil Cytoskeleton (2008) 0.91
STIM1 translocation to the plasma membrane enhances intestinal epithelial restitution by inducing TRPC1-mediated Ca2+ signaling after wounding. Am J Physiol Cell Physiol (2010) 0.91
A novel function of capsaicin-sensitive TRPV1 channels: involvement in cell migration. Cell Calcium (2006) 0.91
KCa3.1 and TRPM7 channels at the uropod regulate migration of activated human T cells. PLoS One (2012) 0.89
TRPV1 expression-dependent initiation and regulation of filopodia. J Neurochem (2007) 0.89
The progesterone receptor regulates the expression of TRPV4 channel. Pflugers Arch (2009) 0.87
Importance of non-selective cation channel TRPV4 interaction with cytoskeleton and their reciprocal regulations in cultured cells. PLoS One (2010) 0.86
Mechanism of cell rear retraction in migrating cells. Curr Opin Cell Biol (2013) 0.84
Role of molecular determinants of store-operated Ca(2+) entry (Orai1, phospholipase A2 group 6, and STIM1) in focal adhesion formation and cell migration. J Biol Chem (2012) 0.84
Calcium/calmodulin-signaling supports TRPV4 activation in osteoclasts and regulates bone mass. J Bone Miner Res (2012) 0.84
Apigenin, a plant-derived flavone, activates transient receptor potential vanilloid 4 cation channel. Br J Pharmacol (2012) 0.82
Rapid vinculin exchange dynamics at focal adhesions in primary osteoblasts following shear flow stimulation. J Musculoskelet Neuronal Interact (2010) 0.80
Nociceptive and pro-inflammatory effects of dimethylallyl pyrophosphate via TRPV4 activation. Br J Pharmacol (2012) 0.79
Activation of TRPV4 channels reduces migration of immortalized neuroendocrine cells. J Neurochem (2011) 0.79
Transient receptor potential canonical channel 1 impacts on mechanosignaling during cell migration. Pflugers Arch (2012) 0.77