Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.

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Published in Am J Clin Nutr on December 10, 2014

Authors

Dariush Mozaffarian1, Edmond K Kabagambe1, Catherine O Johnson1, Rozenn N Lemaitre1, Ani Manichaikul1, Qi Sun1, Millennia Foy1, Lu Wang1, Howard Wiener1, Marguerite R Irvin1, Stephen S Rich1, Hongyu Wu1, Majken K Jensen1, Daniel I Chasman1, Audrey Y Chu1, Myriam Fornage1, Lyn Steffen1, Irena B King1, Barbara McKnight1, Bruce M Psaty1, Luc Djoussé1, Ida Y-D Chen1, Jason H Y Wu1, David S Siscovick1, Paul M Ridker1, Michael Y Tsai1, Eric B Rimm1, Frank B Hu1, Donna K Arnett1

Author Affiliations

1: From the Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA (DM); the Divisions of Cardiovascular Medicine (DM and PMR), Genetics (DIC), Preventive Medicine (LW, DIC, AYC, and PMR), and Aging (LD) and the Channing Division of Network Medicine (DM, QS, EBR, FBH), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; the Departments of Epidemiology (DM, EBR, and FBH) and Nutrition (DM, QS, H Wu, MKJ, EBR, and FBH), Harvard School of Public Health, Boston, MA; the Department of Medicine (COJ, RNL, BMP, and DSS), School of Medicine, and the Departments of Biostatistics (BM), Epidemiology (DSS and BMP), and Health Services (BMP), School of Public Health, University of Washington, Seattle, WA; the Group Health Collaborative Research Institute, Seattle, WA (BMP); Center for Public Health Genomics (AM and SSR) and the Division of Biostatistics (AM), Department of Public Health Sciences, University of Virginia, Charlottesville, VA; the Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (EKK); the Division of Epidemiology & Community Health, School of Public Health (LS) and Department of Laboratory Medicine & Pathology (MYT), University of Minnesota, Minneapolis, MN; Institute of Molecular Medicine (M Foy and M Fornage) and Division of Epidemiology (M Fornage), Human Genetics, and Environmental Science, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX; Division of Genomic Outcomes, Department of Pediatrics, Harbor-UCLA Medical Center, Los Angeles, CA (IY-DC); The George Institute for Global Health, University of Sydney, Australia (JHYW); and the Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL (H Wiener, MRI, and DKA).

Associated clinical trials:

Women's Health Study (WHS): A Randomized Trial of Low-dose Aspirin and Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer (WHS) | NCT00000479

Multi-Ethnic Study of Atherosclerosis (MESA) | NCT00005487

Cardiovascular Health Study (CHS) | NCT00005133

Genetic and Environmental Determinants of Triglycerides (GOLDN) | NCT00083369

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