Published in Mutagenesis on February 26, 2015
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DNA methylation signatures within the human brain. Am J Hum Genet (2007) 3.50
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BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol (2012) 3.24
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Maintaining cell identity through global control of genomic organization. Immunity (2010) 2.03
Maternal tobacco use modestly alters correlated epigenome-wide placental DNA methylation and gene expression. Epigenetics (2011) 1.76
Differential DNA methylation in umbilical cord blood of infants exposed to low levels of arsenic in utero. Environ Health Perspect (2013) 1.66
Epigenetics and cancer: towards an evaluation of the impact of environmental and dietary factors. Mutagenesis (2007) 1.65
Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC). Hum Mol Genet (2014) 1.58
Taking the measure of the methylome. Nat Biotechnol (2010) 1.57
Personalized estimates of breast cancer risk in clinical practice and public health. Stat Med (2011) 1.49
Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans. Genome Res (2012) 1.45
The human early-life exposome (HELIX): project rationale and design. Environ Health Perspect (2014) 1.44
In utero origins of childhood leukaemia. Early Hum Dev (2004) 1.39
Identification of DNA methylation changes in newborns related to maternal smoking during pregnancy. Environ Health Perspect (2014) 1.35
Paediatric cancer in low-income and middle-income countries. Lancet Oncol (2013) 1.35
Epigenetic mechanisms and cancer: an interface between the environment and the genome. Epigenetics (2011) 1.35
Molecular genetics of acute lymphoblastic leukemia. Annu Rev Pathol (2009) 1.34
Archived Guthrie blood spots as a novel source for quantitative DNA methylation analysis. Biotechniques (2008) 1.30
Cohort profile: the International Childhood Cancer Cohort Consortium (I4C). Int J Epidemiol (2007) 1.24
Biomarkers intersect with the exposome. Biomarkers (2012) 1.22
A systematic assessment of normalization approaches for the Infinium 450K methylation platform. Epigenetics (2013) 1.18
Prenatal exposure to maternal cigarette smoking and DNA methylation: epigenome-wide association in a discovery sample of adolescents and replication in an independent cohort at birth through 17 years of age. Environ Health Perspect (2014) 1.17
Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status. J Med Genet (2012) 1.13
Measuring the exposome: a powerful basis for evaluating environmental exposures and cancer risk. Environ Mol Mutagen (2013) 1.08
Sex-specific effects of early life cadmium exposure on DNA methylation and implications for birth weight. Epigenetics (2013) 1.08
Molecular biomarkers for the study of childhood leukemia. Toxicol Appl Pharmacol (2005) 1.04
Hunting for the 5th base: Techniques for analyzing DNA methylation. Biochim Biophys Acta (2009) 1.03
Distinct dynamics and distribution of histone methyl-lysine derivatives in mouse development. Dev Biol (2004) 0.99
Deciphering the complex: methodological overview of statistical models to derive OMICS-based biomarkers. Environ Mol Mutagen (2013) 0.99
Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation. PLoS One (2014) 0.99
Emerging patterns of epigenomic variation. Trends Genet (2011) 0.95
Quantification of DNA methylation in electrofluidics chips (Bio-COBRA). Nat Protoc (2006) 0.93
Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation. Carcinogenesis (2013) 0.92
Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling. BMC Biotechnol (2014) 0.87
The human promoter methylome. Nat Genet (2007) 0.85
Dynamics of epigenetic modifications in leukemia. Brief Funct Genomics (2011) 0.83
Fetal lung and placental methylation is associated with in utero nicotine exposure. Epigenetics (2014) 0.82
RB1 mutation spectrum in a comprehensive nationwide cohort of retinoblastoma patients. J Med Genet (2014) 0.80
The epigenome and cancer prevention: A complex story of dietary supplementation. Cancer Lett (2012) 0.80
Shared mutation for two childhood diseases. J Natl Cancer Inst (2014) 0.76
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks. Nat Cell Biol (2005) 5.11
Epigenetic interplay between histone modifications and DNA methylation in gene silencing. Mutat Res (2008) 2.61
Transforming epidemiology for 21st century medicine and public health. Cancer Epidemiol Biomarkers Prev (2013) 2.56
PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase. J Cell Biol (2007) 2.39
Modulation of DNA methylation states and infant immune system by dietary supplementation with ω-3 PUFA during pregnancy in an intervention study. Am J Clin Nutr (2013) 2.20
An essential function for NBS1 in the prevention of ataxia and cerebellar defects. Nat Med (2005) 2.06
Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling. Mol Biol Cell (2002) 2.05
Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors. PLoS One (2010) 1.84
Quantitative analysis of DNA methylation profiles in lung cancer identifies aberrant DNA methylation of specific genes and its association with gender and cancer risk factors. Cancer Res (2009) 1.84
Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Cancer Lett (2011) 1.62
Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice. Mol Cell Biol (2004) 1.61
Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis. Cancer Res (2003) 1.45
Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks. EMBO J (2006) 1.36
Histone acetylation and chromatin signature in stem cell identity and cancer. Mutat Res (2007) 1.31
Aberrant DNA methylation distinguishes hepatocellular carcinoma associated with HBV and HCV infection and alcohol intake. J Hepatol (2010) 1.26
Oncogenic microRNAs (OncomiRs) as a new class of cancer biomarkers. Bioessays (2010) 1.21
DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study. FASEB J (2012) 1.21
The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells. Carcinogenesis (2005) 1.21
MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells. BMC Genomics (2013) 1.21
Comparisons of microRNA patterns in plasma before and after tumor removal reveal new biomarkers of lung squamous cell carcinoma. PLoS One (2013) 1.17
Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. J Clin Invest (2004) 1.17
An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability. Hum Mol Genet (2004) 1.16
Epigenetic drivers and genetic passengers on the road to cancer. Mutat Res (2008) 1.16
Aberrant DNA methylation links cancer susceptibility locus 15q25.1 to apoptotic regulation and lung cancer. Cancer Res (2010) 1.13
Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection. Mol Cell Biol (2011) 1.10
Parthenolide: from plant shoots to cancer roots. Drug Discov Today (2013) 1.09
Histone modifications and cancer. Adv Genet (2010) 1.08
Measuring the exposome: a powerful basis for evaluating environmental exposures and cancer risk. Environ Mol Mutagen (2013) 1.08
DNA methylation and cancer: ghosts and angels above the genes. Curr Opin Oncol (2011) 1.03
The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair. Mol Cell Biol (2006) 1.01
Quantitative analysis of DNA methylation after whole bisulfitome amplification of a minute amount of DNA from body fluids. Epigenetics (2009) 1.00
Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells. Epigenetics (2011) 0.97
Quantitative detection of DNA methylation states in minute amounts of DNA from body fluids. Methods (2010) 0.97
DNA methylation changes associated with risk factors in tumors of the upper aerodigestive tract. Epigenetics (2012) 0.97
Identification of a DNA methylome signature of esophageal squamous cell carcinoma and potential epigenetic biomarkers. Epigenetics (2011) 0.97
DNA methylation of hepatitis B virus (HBV) genome associated with the development of hepatocellular carcinoma and occult HBV infection. J Infect Dis (2010) 0.96
Integrative genomics identifies gene signature associated with melanoma ulceration. PLoS One (2013) 0.95
HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression. EMBO J (2004) 0.93
Dependence receptor TrkC is a putative colon cancer tumor suppressor. Proc Natl Acad Sci U S A (2013) 0.93
From hepatitis to hepatocellular carcinoma: a proposed model for cross-talk between inflammation and epigenetic mechanisms. Genome Med (2012) 0.93
Epigenetic information in chromatin: the code of entry for DNA repair. Cell Cycle (2006) 0.92
Deletion of the nuclear isoform of poly(ADP-ribose) glycohydrolase (PARG) reveals its function in DNA repair, genomic stability and tumorigenesis. Carcinogenesis (2010) 0.92
DNA methylation changes associated with cancer risk factors and blood levels of vitamin metabolites in a prospective study. Epigenetics (2011) 0.92
Deciphering the epigenetic code: an overview of DNA methylation analysis methods. Antioxid Redox Signal (2013) 0.91
Chromatin structure in double strand break repair. DNA Repair (Amst) (2013) 0.90
Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers. Int J Cancer (2011) 0.90
Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome. Epigenetics (2012) 0.90
Epigenetic Signatures of Cigarette Smoking. Circ Cardiovasc Genet (2016) 0.88
Shaping chromatin for repair. Mutat Res (2012) 0.88
CHRNA5 as negative regulator of nicotine signaling in normal and cancer bronchial cells: effects on motility, migration and p63 expression. Carcinogenesis (2011) 0.88
Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling. BMC Biotechnol (2014) 0.87
Epigenetics and cancer, 2nd IARC meeting, Lyon, France, 6 and 7 December 2007. Mol Oncol (2008) 0.87
DNA demethylating agents and epigenetic therapy of cancer. Adv Genet (2010) 0.86
Epigenetic signatures in cancer: Implications for the control of cancer in the clinic. Curr Opin Mol Ther (2010) 0.86
The combination of arsenic, interferon-alpha, and zidovudine restores an "immunocompetent-like" cytokine expression profile in patients with adult T-cell leukemia lymphoma. Retrovirology (2013) 0.86
Epigenetic silencing of sFRP1 activates the canonical Wnt pathway and contributes to increased cell growth and proliferation in hepatocellular carcinoma. Tumour Biol (2012) 0.86
HAT cofactor TRRAP mediates beta-catenin ubiquitination on the chromatin and the regulation of the canonical Wnt pathway. Cell Cycle (2008) 0.85
Intensity-dependent constitutional MLH1 promoter methylation leads to early onset of colorectal cancer by affecting both alleles. Genes Chromosomes Cancer (2010) 0.84
Methylome analysis and epigenetic changes associated with menarcheal age. PLoS One (2013) 0.84
Transcriptional regulation of the human tumor suppressor DOK1 by E2F1. Mol Cell Biol (2012) 0.83
Challenges and opportunities in research on early-life events/exposures and cancer development later in life. Cancer Causes Control (2012) 0.83
Epstein - Barr virus transforming protein LMP-1 alters B cells gene expression by promoting accumulation of the oncoprotein ΔNp73α. PLoS Pathog (2013) 0.83
Histone acetyltransferase cofactor Trrap maintains self-renewal and restricts differentiation of embryonic stem cells. Stem Cells (2013) 0.83
Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool. J Immunol (2009) 0.82
Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-β) is associated with a DNA methylome switch. BMC Genomics (2014) 0.82
Methylation patterns in sentinel genes in peripheral blood cells of heavy smokers: Influence of cruciferous vegetables in an intervention study. Epigenetics (2011) 0.81
Epigenetic mechanisms of plant-derived anticancer drugs. Front Biosci (Landmark Ed) (2012) 0.81
Epigenetic signatures in stem cells and cancer stem cells. Epigenomics (2009) 0.81
Detection of cancer-specific epigenomic changes in biofluids: powerful tools in biomarker discovery and application. Mol Oncol (2012) 0.81
Developmental and transplacental genotoxicology: fluconazole. Mutat Res (2008) 0.80
Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours. Eur J Hum Genet (2013) 0.80
The epigenome and cancer prevention: A complex story of dietary supplementation. Cancer Lett (2012) 0.80
PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models. BMC Cancer (2014) 0.79
Loss of histone acetyltransferase cofactor transformation/transcription domain-associated protein impairs liver regeneration after toxic injury. Hepatology (2011) 0.78
Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters. J Virol (2013) 0.77
HBV protein as a double-barrel shot-gun targets epigenetic landscape in liver cancer. J Hepatol (2008) 0.77
Transposable hypomethylation is associated with metastatic capacity of primary melanomas. Int J Clin Exp Pathol (2013) 0.77
Histone code in the cross-talk during DNA damage signaling. Cell Res (2010) 0.77
Epigenetics is a fascinating field of modern biology. Preface. Adv Genet (2010) 0.76
Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter-induced transformation of JB6 cells. BMC Complement Altern Med (2012) 0.76
New concepts of old epigenetic phenomena and their implications for selecting specific cell populations for epigenomic research. Epigenomics (2011) 0.76
Combination of arsenic and interferon-α inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomas. PLoS One (2013) 0.75
Reply to GC Burdge. Am J Clin Nutr (2013) 0.75
Comparative genomic analysis of esophageal cancers. Ann N Y Acad Sci (2014) 0.75