Published in Hum Mol Genet on April 15, 2006
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DNA methylation signatures within the human brain. Am J Hum Genet (2007) 3.50
A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity. Cell (2012) 2.72
Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patterns. Genome Res (2006) 2.67
Environmental epigenetics and asthma: current concepts and call for studies. Am J Respir Crit Care Med (2008) 2.26
Developmental origins of health and disease: brief history of the approach and current focus on epigenetic mechanisms. Semin Reprod Med (2009) 2.03
Tissue-specific expression and post-translational modification of histone H3 variants. J Proteome Res (2008) 1.84
What is an epigenetic transgenerational phenotype? F3 or F2. Reprod Toxicol (2007) 1.79
Application of OMICS technologies in occupational and environmental health research; current status and projections. Occup Environ Med (2009) 1.67
Epigenetic mediation of environmental influences in major psychotic disorders. Schizophr Bull (2009) 1.47
The impact of new research technologies on our understanding of environmental causes of disease: the concept of clinical vulnerability. Environ Health (2009) 1.31
Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells. Cancer Res (2008) 1.30
Grand challenges in evolutionary and population genetics: the importance of integrating epigenetics, genomics, modeling, and experimentation. Front Genet (2014) 1.29
Epigenetic alterations in aging. J Appl Physiol (1985) (2010) 1.20
Early life nutrition, epigenetics and programming of later life disease. Nutrients (2014) 1.18
Beyond genetics: epigenetic code in chronic kidney disease. Kidney Int (2010) 1.18
Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing. Nucleic Acids Res (2011) 1.15
Evolution of DOHaD: the impact of environmental health sciences. J Dev Orig Health Dis (2014) 1.08
Developmental origins of child mental health disorders. J Child Psychol Psychiatry (2008) 1.07
Epigenetic allele silencing unveils recessive RYR1 mutations in core myopathies. Am J Hum Genet (2006) 1.07
Molecular targets of epigenetic regulation and effectors of environmental influences. Toxicol Appl Pharmacol (2010) 1.05
From 'omics' to complex disease: a systems biology approach to gene-environment interactions in cancer. Cancer Cell Int (2010) 1.02
Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growth. Am J Physiol Gastrointest Liver Physiol (2010) 1.02
Epigenetic mechanisms and models in the origins of asthma. Curr Opin Allergy Clin Immunol (2013) 1.02
Epigenetic regulation of caloric restriction in aging. BMC Med (2011) 0.99
Analyzing the cancer methylome through targeted bisulfite sequencing. Cancer Lett (2012) 0.96
Epigenetics: Beyond Chromatin Modifications and Complex Genetic Regulation. Plant Physiol (2014) 0.95
Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. Alcohol Clin Exp Res (2007) 0.95
Epigenetic changes (aberrant DNA methylation) in colorectal neoplasia. Gut Liver (2007) 0.94
Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders. Pharmacol Ther (2014) 0.92
How the epigenome contributes to the development of psychiatric disorders. Dev Psychobiol (2010) 0.92
Targeting the epigenome with bioactive food components for cancer prevention. J Nutrigenet Nutrigenomics (2012) 0.91
Statistical genetics concepts and approaches in schizophrenia and related neuropsychiatric research. Schizophr Bull (2006) 0.91
Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium. Hum Reprod Update (2013) 0.89
Seed in soil, with an epigenetic view. Biochim Biophys Acta (2008) 0.86
Epigenetics and miRNA emerge as key regulators of smooth muscle cell phenotype and function. Pulm Pharmacol Ther (2012) 0.85
Competence and regulatory interactions during regeneration in plants. Front Plant Sci (2014) 0.84
Metabolomic fingerprinting: challenges and opportunities. Crit Rev Biomed Eng (2013) 0.82
Genetic and epigenetic alterations in breast cancer: what are the perspectives for clinical practice? Int J Biochem Cell Biol (2007) 0.82
Cancer gene discovery in mouse and man. Biochim Biophys Acta (2009) 0.81
The BisPCR(2) method for targeted bisulfite sequencing. Epigenetics Chromatin (2015) 0.81
Epigenomics in cancer management. Cancer Manag Res (2010) 0.81
Characterising the epigenome as a key component of the fetal exposome in evaluating in utero exposures and childhood cancer risk. Mutagenesis (2015) 0.80
Sex and the single nucleotide polymorphism: exploring the genetic causes of skeletal sex differences. J Bone Miner Res (2012) 0.79
DNA methylation analysis in human cancer. Methods Mol Biol (2013) 0.79
Implications of systemic dysfunction for the etiology of malignancy. Gene Regul Syst Bio (2013) 0.78
Developmental origins of adult diseases. Indian J Endocrinol Metab (2012) 0.78
High-content analysis of cancer genome DNA alterations. Curr Opin Genet Dev (2008) 0.77
pENCODE: a plant encyclopedia of DNA elements. Annu Rev Genet (2014) 0.77
Genome-wide methylation and transcriptome analysis in penile carcinoma: uncovering new molecular markers. Clin Epigenetics (2015) 0.76
Maternal folate status and obesity/insulin resistance in the offspring: a systematic review. Int J Obes (Lond) (2015) 0.76
Chromosome-wide analysis of protein binding and modifications. Methods Mol Biol (2009) 0.75
Childhood cancer and environmental integrity: a commentary and a proposal. Rev Saude Publica (2017) 0.75
Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes. Int J Nanomedicine (2016) 0.75
Inhibition of H3K9 methyltransferase G9a ameliorates methylglyoxal-induced peritoneal fibrosis. PLoS One (2017) 0.75
Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice. J Clin Invest (2017) 0.75
Epigenetic: A missing paradigm in cellular and molecular pathways of sulfur mustard lung: a prospective and comparative study. Iran J Basic Med Sci (2015) 0.75
Achieving HIV-1 Control through RNA-Directed Gene Regulation. Genes (Basel) (2016) 0.75
Bioinformatic Dissecting of TP53 Regulation Pathway Underlying Butyrate-induced Histone Modification in Epigenetic Regulation. Genet Epigenet (2014) 0.75
Emerging Role of Nutri-Epigenetics in Inflammation and Cancer. Oncol Nurs Forum (2016) 0.75
Brassica-Derived Plant Bioactives as Modulators of Chemopreventive and Inflammatory Signaling Pathways. Int J Mol Sci (2017) 0.75
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet (2009) 10.54
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature (2002) 9.40
Increased methylation variation in epigenetic domains across cancer types. Nat Genet (2011) 8.92
Comprehensive high-throughput arrays for relative methylation (CHARM). Genome Res (2008) 8.62
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature (2008) 7.64
Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science (2003) 6.85
Intra-individual change over time in DNA methylation with familial clustering. JAMA (2008) 6.17
Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature (2010) 6.06
Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays. Bioinformatics (2014) 5.93
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol (2013) 5.89
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells. Nat Genet (2009) 5.52
An integrated epigenetic and genetic approach to common human disease. Trends Genet (2004) 4.89
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci U S A (2002) 4.27
An X chromosome gene, WTX, is commonly inactivated in Wilms tumor. Science (2007) 4.00
Association of in vitro fertilization with Beckwith-Wiedemann syndrome and epigenetic alterations of LIT1 and H19. Am J Hum Genet (2002) 3.93
Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies. Int J Epidemiol (2012) 3.62
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation. Nat Genet (2004) 3.56
A genome-wide screen for normally methylated human CpG islands that can identify novel imprinted genes. Genome Res (2002) 3.50
DNA methylation signatures within the human brain. Am J Hum Genet (2007) 3.50
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat Biotechnol (2011) 3.25
Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2. Cancer Res (2002) 3.21
Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition. Nat Struct Mol Biol (2011) 3.00
Epigenetic alterations of H19 and LIT1 distinguish patients with Beckwith-Wiedemann syndrome with cancer and birth defects. Am J Hum Genet (2002) 2.73
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. Cancer Cell (2004) 2.73
Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice. Science (2005) 2.72
BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. Proc Natl Acad Sci U S A (2002) 2.62
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity. Cancer Res (2002) 2.52
Reversible switching between epigenetic states in honeybee behavioral subcastes. Nat Neurosci (2012) 2.44
Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat Rev Cancer (2013) 2.41
Epigenetics and assisted reproductive technology: a call for investigation. Am J Hum Genet (2004) 2.41
SNP-specific array-based allele-specific expression analysis. Genome Res (2008) 2.30
Accurate genome-scale percentage DNA methylation estimates from microarray data. Biostatistics (2010) 2.11
Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. Gastroenterology (2004) 2.06
Redefining CpG islands using hidden Markov models. Biostatistics (2010) 2.03
Association between Beckwith-Wiedemann syndrome and assisted reproductive technology: a case series of 19 patients. Fertil Steril (2005) 1.87
Regulated noise in the epigenetic landscape of development and disease. Cell (2012) 1.79
A nucleolar protein, H19 opposite tumor suppressor (HOTS), is a tumor growth inhibitor encoded by a human imprinted H19 antisense transcript. Proc Natl Acad Sci U S A (2011) 1.77
Significance analysis and statistical dissection of variably methylated regions. Biostatistics (2011) 1.74
Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells. Mol Cancer Ther (2007) 1.42
Loss of imprinting of IGF2: a common epigenetic modifier of intestinal tumor risk. Cancer Res (2005) 1.39
Microdeletion of LIT1 in familial Beckwith-Wiedemann syndrome. Am J Hum Genet (2004) 1.38
A species-generalized probabilistic model-based definition of CpG islands. Mamm Genome (2009) 1.36
Large-scale hypomethylated blocks associated with Epstein-Barr virus-induced B-cell immortalization. Genome Res (2013) 1.34
DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth. Int J Epidemiol (2012) 1.30
Epigenetic specificity of loss of imprinting of the IGF2 gene in Wilms tumors. J Natl Cancer Inst (2007) 1.29
BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression. Mol Cell Biol (2008) 1.26
Measuring cell-type specific differential methylation in human brain tissue. Genome Biol (2013) 1.19
DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation. Cancer Res (2008) 1.17
Genome-wide DNA methylation scan in major depressive disorder. PLoS One (2012) 1.17
Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk. Proc Natl Acad Sci U S A (2007) 1.15
Higher order chromatin organization in cancer. Semin Cancer Biol (2012) 1.09
Overlapping euchromatin/heterochromatin- associated marks are enriched in imprinted gene regions and predict allele-specific modification. Genome Res (2008) 1.06
Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages. Proc Natl Acad Sci U S A (2002) 1.05
Comprehensive high-throughput arrays for relative methylation (CHARM). Curr Protoc Hum Genet (2010) 1.02
Genetics and epigenetics--nature's pen-and-pencil set. N Engl J Med (2007) 1.02
CTCFL/BORIS is a methylation-independent DNA-binding protein that preferentially binds to the paternal H19 differentially methylated region. Cancer Res (2008) 0.99
The commonality of plasticity underlying multipotent tumor cells and embryonic stem cells. J Cell Biochem (2007) 0.97
Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions. BMC Genomics (2012) 0.94
Children with idiopathic hemihypertrophy and beckwith-wiedemann syndrome have different constitutional epigenotypes associated with wilms tumor. Am J Hum Genet (2005) 0.93
A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol (2014) 0.92
Temporal stability and age-related prevalence of loss of imprinting of the insulin-like growth factor-2 gene. Epigenetics (2009) 0.91
Factors associated with preterm delivery in mothers of children with Beckwith-Wiedemann syndrome: a case cohort study from the BWS registry. Am J Med Genet A (2005) 0.90
A new link between epigenetic progenitor lesions in cancer and the dynamics of signal transduction. Cell Cycle (2009) 0.87
Adaptation of the CHARM DNA methylation platform for the rat genome reveals novel brain region-specific differences. Epigenetics (2011) 0.84
Association of chromosome arm 16q loss with loss of imprinting of insulin-like growth factor-II in Wilms tumor. Genes Chromosomes Cancer (2005) 0.82
Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1. Am J Med Genet B Neuropsychiatr Genet (2008) 0.82
Addition of H19 'loss of methylation testing' for Beckwith-Wiedemann syndrome (BWS) increases the diagnostic yield. J Mol Diagn (2010) 0.82
Epigenetic variability and the evolution of human cancer. Adv Cancer Res (2003) 0.80
Inheritance pattern of Beckwith-Wiedemann syndrome is heterogeneous in 291 families with an affected proband. Am J Med Genet A (2005) 0.75
Stem cell differentiation as a renewal-reward process: predictions and validation in the colonic crypt. Adv Exp Med Biol (2012) 0.75
Lack of parental origin specificity of altered alleles at 11p15 in testicular germ cell tumors. Cancer Genet Cytogenet (2003) 0.75