Published in Am J Med Sci on April 01, 2015
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med (2012) 13.48
TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol (2005) 7.55
Stereotaxic white matter atlas based on diffusion tensor imaging in an ICBM template. Neuroimage (2008) 6.58
Improved overall survival in melanoma with combined dabrafenib and trametinib. N Engl J Med (2014) 5.65
Tract probability maps in stereotaxic spaces: analyses of white matter anatomy and tract-specific quantification. Neuroimage (2007) 5.23
Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes. Nat Biotechnol (2011) 4.84
Cancer burden in the HIV-infected population in the United States. J Natl Cancer Inst (2011) 4.69
The DNA methylome of human peripheral blood mononuclear cells. PLoS Biol (2010) 4.25
Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial. Lancet Oncol (2012) 4.19
The pulvinar regulates information transmission between cortical areas based on attention demands. Science (2012) 4.14
Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model. J Clin Invest (2008) 4.13
Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation. Immunity (2011) 3.75
Atlas-based whole brain white matter analysis using large deformation diffeomorphic metric mapping: application to normal elderly and Alzheimer's disease participants. Neuroimage (2009) 3.74
Gradient-index meta-surfaces as a bridge linking propagating waves and surface waves. Nat Mater (2012) 3.42
Silencing by small RNAs is linked to endosomal trafficking. Nat Cell Biol (2009) 3.25
Integrated 3D-printed reactionware for chemical synthesis and analysis. Nat Chem (2012) 3.23
VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors. Cancer Cell (2011) 3.23
Magnetic field and tissue dependencies of human brain longitudinal 1H2O relaxation in vivo. Magn Reson Med (2007) 3.23
A gain-of-function mutation in a plant disease resistance gene leads to constitutive activation of downstream signal transduction pathways in suppressor of npr1-1, constitutive 1. Plant Cell (2003) 3.00
Human brain white matter atlas: identification and assignment of common anatomical structures in superficial white matter. Neuroimage (2008) 2.86
The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans. J Immunol (2008) 2.71
The phytochrome-interacting transcription factor, PIF3, acts early, selectively, and positively in light-induced chloroplast development. Proc Natl Acad Sci U S A (2004) 2.71
On the origin of new genes in Drosophila. Genome Res (2008) 2.69
Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase. Antimicrob Agents Chemother (2003) 2.66
TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi. Cell (2004) 2.62
Memory CD4+ T cells do not induce graft-versus-host disease. J Clin Invest (2003) 2.54
A randomized controlled trial of radiofrequency ablation and surgical resection in the treatment of small hepatocellular carcinoma. J Hepatol (2012) 2.53
Outsourcing CO2 within China. Proc Natl Acad Sci U S A (2013) 2.51
Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells. Nat Cell Biol (2003) 2.50
C. elegans screen identifies autophagy genes specific to multicellular organisms. Cell (2010) 2.50
MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin. Cancer Lett (2008) 2.48
The scavenger receptor MARCO is required for lung defense against pneumococcal pneumonia and inhaled particles. J Exp Med (2004) 2.46
Multi-contrast human neonatal brain atlas: application to normal neonate development analysis. Neuroimage (2011) 2.41
MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. Biochem Biophys Res Commun (2009) 2.39
Knockout analysis of Arabidopsis transcription factors TGA2, TGA5, and TGA6 reveals their redundant and essential roles in systemic acquired resistance. Plant Cell (2003) 2.35
Proportions of Kaposi sarcoma, selected non-Hodgkin lymphomas, and cervical cancer in the United States occurring in persons with AIDS, 1980-2007. JAMA (2011) 2.31
Variation of the relaxographic "shutter-speed" for transcytolemmal water exchange affects the CR bolus-tracking curve shape. Magn Reson Med (2003) 2.23
Transjugular intrahepatic portosystemic shunt for Budd-Chiari syndrome: techniques, indications and results on 51 Chinese patients from a single centre. Liver Int (2013) 2.22
Contour-based object tracking with occlusion handling in video acquired using mobile cameras. IEEE Trans Pattern Anal Mach Intell (2004) 2.22
Atlas-guided tract reconstruction for automated and comprehensive examination of the white matter anatomy. Neuroimage (2010) 2.21
Retention in care of adults and adolescents living with HIV in 13 U.S. areas. J Acquir Immune Defic Syndr (2012) 2.15
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet (2011) 2.13
The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo. Am J Hematol (2009) 2.12
Transjugular intrahepatic portosystemic shunt for portal vein thrombosis with symptomatic portal hypertension in liver cirrhosis. J Hepatol (2010) 2.11
Imaging transforming growth factor-beta signaling dynamics and therapeutic response in breast cancer bone metastasis. Nat Med (2009) 2.10
Comparison of intravitreal triamcinolone acetonide versus intravitreal bevacizumab as the primary treatment of clinically significant macular edema. Retina (2015) 2.08
SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res (2005) 2.07
A putative nucleoporin 96 Is required for both basal defense and constitutive resistance responses mediated by suppressor of npr1-1,constitutive 1. Plant Cell (2005) 2.06
Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression. Cell (2012) 2.06
Quantification of increased cellularity during inflammatory demyelination. Brain (2011) 2.05
Single base-resolution methylome of the silkworm reveals a sparse epigenomic map. Nat Biotechnol (2010) 2.03
IFN-gamma-producing gamma delta T cells help control murine West Nile virus infection. J Immunol (2003) 2.03
Racial and Ethnic Disparities in Hospital Readmissions After Delivery. Obstet Gynecol (2015) 2.01
Multi-contrast large deformation diffeomorphic metric mapping for diffusion tensor imaging. Neuroimage (2009) 2.01
Mechanism by which orally administered beta-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models. J Immunol (2004) 2.00
Laparoscopic versus conventional appendectomy--a meta-analysis of randomized controlled trials. BMC Gastroenterol (2010) 1.99
Syntaxin 2 and endobrevin are required for the terminal step of cytokinesis in mammalian cells. Dev Cell (2003) 1.99
Nuclear pore complex component MOS7/Nup88 is required for innate immunity and nuclear accumulation of defense regulators in Arabidopsis. Plant Cell (2009) 1.96
Regulation of cell death and innate immunity by two receptor-like kinases in Arabidopsis. Cell Host Microbe (2009) 1.93
Dehalococcoides mccartyi gen. nov., sp. nov., obligately organohalide-respiring anaerobic bacteria relevant to halogen cycling and bioremediation, belong to a novel bacterial class, Dehalococcoidia classis nov., order Dehalococcoidales ord. nov. and family Dehalococcoidaceae fam. nov., within the phylum Chloroflexi. Int J Syst Evol Microbiol (2012) 1.93
Isolation and characterization of phyC mutants in Arabidopsis reveals complex crosstalk between phytochrome signaling pathways. Plant Cell (2003) 1.90
Atlas-based analysis of neurodevelopment from infancy to adulthood using diffusion tensor imaging and applications for automated abnormality detection. Neuroimage (2010) 1.89
Meningiomas in children and adolescents: a meta-analysis of individual patient data. Lancet Oncol (2011) 1.88
The clinical pathology of severe acute respiratory syndrome (SARS): a report from China. J Pathol (2003) 1.83
Borrelia burgdorferi changes its surface antigenic expression in response to host immune responses. Infect Immun (2004) 1.82
Beta-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells. Cancer Res (2003) 1.81
Human neural stem cell grafts ameliorate motor neuron disease in SOD-1 transgenic rats. Transplantation (2006) 1.80
MiR-150 promotes gastric cancer proliferation by negatively regulating the pro-apoptotic gene EGR2. Biochem Biophys Res Commun (2010) 1.80
Loss of function of OsDCL1 affects microRNA accumulation and causes developmental defects in rice. Plant Physiol (2005) 1.77
A double-blind, randomized, controlled trial of amphotericin B colloidal dispersion versus amphotericin B for treatment of invasive aspergillosis in immunocompromised patients. Clin Infect Dis (2002) 1.77
Chemical-genomic dissection of the CTD code. Nat Struct Mol Biol (2010) 1.76
Proteus mirabilis genes that contribute to pathogenesis of urinary tract infection: identification of 25 signature-tagged mutants attenuated at least 100-fold. Infect Immun (2004) 1.76
MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-kappaB1. FEBS J (2009) 1.74
Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation. J Clin Invest (2015) 1.74
Stable isotope resolved metabolomics of lung cancer in a SCID mouse model. Metabolomics (2011) 1.73
Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence. Genome Res (2012) 1.73
BLADE-ON-PETIOLE-dependent signaling controls leaf and floral patterning in Arabidopsis. Plant Cell (2005) 1.73
Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-gamma, and proinflammatory adipokines. Circulation (2008) 1.73
Meta-analysis on the relationship between nonsteroidal anti-inflammatory drug use and gastric cancer. Eur J Cancer Prev (2010) 1.72
Hypoglycemic and hypolipidemic effects and antioxidant activity of fruit extracts from Lycium barbarum. Life Sci (2004) 1.71
Clonal persistence and evolution during a decade of recurrent melanoma. J Invest Dermatol (2006) 1.69
Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis. PLoS Genet (2007) 1.68
Unlocking the potential of cation-disordered oxides for rechargeable lithium batteries. Science (2014) 1.67
Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature (2011) 1.67
The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites. Biochem Biophys Res Commun (2009) 1.67
Changes in invasive Pneumococcal disease among HIV-infected adults living in the era of childhood pneumococcal immunization. Ann Intern Med (2006) 1.67
ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 repress SALICYLIC ACID INDUCTION DEFICIENT2 expression to negatively regulate plant innate immunity in Arabidopsis. Plant Cell (2009) 1.67
Vaccine protection against Zika virus from Brazil. Nature (2016) 1.65
Evidence for shutter-speed variation in CR bolus-tracking studies of human pathology. NMR Biomed (2005) 1.65
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol (2009) 1.65
PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo. Cancer Biol Ther (2005) 1.64
Angiotensin II diminishes the effect of SGK1 on the WNK4-mediated inhibition of ROMK1 channels. Kidney Int (2010) 1.64
Seroadaptive practices: association with HIV acquisition among HIV-negative men who have sex with men. PLoS One (2012) 1.64
Prevalence of covert duplicate publications in Budd-Chiari syndrome articles in China: a systematic analysis. Am J Med (2013) 1.63
Synthesis and electromagnetic, microwave absorbing properties of core-shell Fe3O4-poly(3, 4-ethylenedioxythiophene) microspheres. ACS Appl Mater Interfaces (2011) 1.62
Therapeutic targeting of cancer cell metabolism. J Mol Med (Berl) (2011) 1.62
Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways. J Pathol (2004) 1.62
MicroRNA-224 is involved in transforming growth factor-beta-mediated mouse granulosa cell proliferation and granulosa cell function by targeting Smad4. Mol Endocrinol (2010) 1.61
Impaired M. tuberculosis-mediated apoptosis in alveolar macrophages from HIV+ persons: potential role of IL-10 and BCL-3. J Leukoc Biol (2009) 1.61
Induction of regulatory T cells by physiological level estrogen. J Cell Physiol (2008) 1.59