Published in J Immunol on September 01, 2003
Role of CD8+ T cells in control of West Nile virus infection. J Virol (2004) 3.40
Genomic analysis of the host response to hepatitis B virus infection. Proc Natl Acad Sci U S A (2004) 3.16
Pathogenesis of West Nile Virus infection: a balance between virulence, innate and adaptive immunity, and viral evasion. J Virol (2006) 3.15
Ly6c+ "inflammatory monocytes" are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis. J Exp Med (2008) 3.08
A critical role for induced IgM in the protection against West Nile virus infection. J Exp Med (2003) 2.89
Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing. Immunity (2009) 2.66
CD4+ T-cell responses are required for clearance of West Nile virus from the central nervous system. J Virol (2006) 2.44
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CD8+ T cells require perforin to clear West Nile virus from infected neurons. J Virol (2006) 2.31
Tregs control the development of symptomatic West Nile virus infection in humans and mice. J Clin Invest (2009) 2.18
Protective immune responses against West Nile virus are primed by distinct complement activation pathways. J Exp Med (2006) 2.11
Gamma interferon plays a crucial early antiviral role in protection against West Nile virus infection. J Virol (2006) 1.84
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Complement activation is required for induction of a protective antibody response against West Nile virus infection. J Virol (2005) 1.75
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CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis. Proc Natl Acad Sci U S A (2008) 1.60
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Epidermal T cells and wound healing. J Immunol (2010) 1.58
Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion. J Clin Invest (2007) 1.57
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CD40-CD40 ligand interactions promote trafficking of CD8+ T cells into the brain and protection against West Nile virus encephalitis. J Virol (2007) 1.30
Functions of skin-resident γδ T cells. Cell Mol Life Sci (2011) 1.27
Progress on the development of therapeutics against West Nile virus. Antiviral Res (2009) 1.26
The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development. Immunol Rev (2009) 1.25
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Role of two distinct gammadelta T cell subsets during West Nile virus infection. FEMS Immunol Med Microbiol (2008) 0.97
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Regulatory T cells shape the resident memory T cell response to virus infection in the tissues. J Immunol (2013) 0.95
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The West Nile virus-like flavivirus Koutango is highly virulent in mice due to delayed viral clearance and the induction of a poor neutralizing antibody response. J Virol (2014) 0.95
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Oral administration of active hexose correlated compound enhances host resistance to West Nile encephalitis in mice. J Nutr (2009) 0.89
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Role of natural killer and Gamma-delta T cells in West Nile virus infection. Viruses (2013) 0.86
Important roles for gamma interferon and NKG2D in gammadelta T-cell-induced demyelination in T-cell receptor beta-deficient mice infected with a coronavirus. J Virol (2005) 0.85
Repeated in vivo stimulation of T and B cell responses in old mice generates protective immunity against lethal West Nile virus encephalitis. J Immunol (2011) 0.85
CD8 and CD4 T cells in west nile virus immunity and pathogenesis. Viruses (2013) 0.83
Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption. PLoS One (2014) 0.83
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The co-stimulatory effects of MyD88-dependent Toll-like receptor signaling on activation of murine γδ T cells. PLoS One (2014) 0.82
Early IFN-gamma production after YF 17D vaccine virus immunization in mice and its association with adaptive immune responses. PLoS One (2013) 0.82
Subcapsular sinus macrophages limit dissemination of West Nile virus particles after inoculation but are not essential for the development of West Nile virus-specific T cell responses. Virology (2014) 0.81
Identification of novel gammadelta T-cell subsets following bacterial infection in the absence of Vgamma1+ T cells: homeostatic control of gammadelta T-cell responses to pathogen infection by Vgamma1+ T cells. Infect Immun (2006) 0.81
Dysregulation of Toll-Like Receptor 7 Compromises Innate and Adaptive T Cell Responses and Host Resistance to an Attenuated West Nile Virus Infection in Old Mice. J Virol (2015) 0.80
γδ T Cells Play a Protective Role in Chikungunya Virus-Induced Disease. J Virol (2015) 0.80
Risk factors for West Nile virus infection and disease in populations and individuals. Expert Rev Anti Infect Ther (2015) 0.79
TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets. Nat Immunol (2016) 0.78
IL-33 promotes innate IFN-γ production and modulates dendritic cell response in LCMV-induced hepatitis in mice. Eur J Immunol (2015) 0.78
Mice deficient in interferon-gamma or interferon-gamma receptor 1 have distinct inflammatory responses to acute viral encephalomyelitis. PLoS One (2013) 0.78
CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system. J Neuroinflammation (2015) 0.78
PIN: a novel protein involved in IFN-gamma accumulation of NOS-1 in neurons. DNA Cell Biol (2008) 0.78
CD8 T cells protect adult naive mice from JEV-induced morbidity via lytic function. PLoS Negl Trop Dis (2017) 0.78
Immunization with Culex tarsalis mosquito salivary gland extract modulates West Nile virus infection and disease in mice. Viral Immunol (2013) 0.77
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Association of γδ T Cell Compartment Size to Disease Activity and Response to Therapy in SLE. PLoS One (2016) 0.75
Adaptive immune response to viral infections in the central nervous system. Handb Clin Neurol (2014) 0.75
Stress hormones predict a host superspreader phenotype in the West Nile virus system. Proc Biol Sci (2017) 0.75
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science (2009) 9.22
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions. Nat Genet (2006) 8.99
The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus. Cell (2009) 7.88
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science (2008) 7.59
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med (2004) 7.49
RNA interference screen for human genes associated with West Nile virus infection. Nature (2008) 4.93
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science (2011) 4.76
Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model. J Clin Invest (2008) 4.13
Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation. Immunity (2011) 3.75
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc Natl Acad Sci U S A (2003) 3.46
The circadian clock controls toll-like receptor 9-mediated innate and adaptive immunity. Immunity (2012) 3.43
ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity. J Exp Med (2008) 3.39
OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands. J Clin Invest (2004) 3.38
Integrated 3D-printed reactionware for chemical synthesis and analysis. Nat Chem (2012) 3.23
VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors. Cancer Cell (2011) 3.23
Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J Exp Med (2004) 3.02
The Lyme disease agent exploits a tick protein to infect the mammalian host. Nature (2005) 2.82
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. Nat Med (2002) 2.77
Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing. Immunity (2009) 2.66
In vivo regulation of Bcl6 and T follicular helper cell development. J Immunol (2010) 2.63
Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response. J Immunol (2010) 2.63
TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi. Cell (2004) 2.62
Host feeding patterns of Culex mosquitoes and West Nile virus transmission, northeastern United States. Emerg Infect Dis (2006) 2.58
Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. J Neuropathol Exp Neurol (2005) 2.58
Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection. Immunity (2011) 2.54
Memory CD4+ T cells do not induce graft-versus-host disease. J Clin Invest (2003) 2.54
Blood (1->3)-beta-D-glucan as a diagnostic test for HIV-related Pneumocystis jirovecii pneumonia. Clin Infect Dis (2011) 2.54
A randomized controlled trial of radiofrequency ablation and surgical resection in the treatment of small hepatocellular carcinoma. J Hepatol (2012) 2.53
Molecular adaptation of Borrelia burgdorferi in the murine host. J Exp Med (2002) 2.49
Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes. J Virol (2006) 2.20
Age-associated defect in human TLR-1/2 function. J Immunol (2007) 2.20
A tick antioxidant facilitates the Lyme disease agent's successful migration from the mammalian host to the arthropod vector. Cell Host Microbe (2007) 2.17
Epidemiology of West Nile virus in Connecticut: a five-year analysis of mosquito data 1999-2003. Vector Borne Zoonotic Dis (2004) 2.15
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet (2011) 2.13
Rab 5 is required for the cellular entry of dengue and West Nile viruses. J Virol (2007) 2.12
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Imaging transforming growth factor-beta signaling dynamics and therapeutic response in breast cancer bone metastasis. Nat Med (2009) 2.10
Regulation of pulmonary fibrosis by chemokine receptor CXCR3. J Clin Invest (2004) 2.10
Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections. Immunity (2007) 2.07
SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res (2005) 2.07
Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression. Cell (2012) 2.06
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Racial and Ethnic Disparities in Hospital Readmissions After Delivery. Obstet Gynecol (2015) 2.01
Mechanism by which orally administered beta-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models. J Immunol (2004) 2.00
Human innate immunosenescence: causes and consequences for immunity in old age. Trends Immunol (2009) 2.00
Endovascular foreign body retrieval. J Vasc Surg (2012) 1.99
Gamma delta T cells provide an early source of interferon gamma in tumor immunity. J Exp Med (2003) 1.99
Dysregulation of TLR3 impairs the innate immune response to West Nile virus in the elderly. J Virol (2008) 1.93
Dehalococcoides mccartyi gen. nov., sp. nov., obligately organohalide-respiring anaerobic bacteria relevant to halogen cycling and bioremediation, belong to a novel bacterial class, Dehalococcoidia classis nov., order Dehalococcoidales ord. nov. and family Dehalococcoidaceae fam. nov., within the phylum Chloroflexi. Int J Syst Evol Microbiol (2012) 1.93
Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus. Arthritis Res Ther (2010) 1.93
A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice. J Immunol (2010) 1.91
Long-term outcome after epilepsy surgery for focal cortical dysplasia. J Neurosurg (2004) 1.87
Coordinated regulation of polycomb group complexes through microRNAs in cancer. Cancer Cell (2011) 1.86
Gamma interferon plays a crucial early antiviral role in protection against West Nile virus infection. J Virol (2006) 1.84
n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner. Diabetes (2007) 1.84
Borrelia burgdorferi changes its surface antigenic expression in response to host immune responses. Infect Immun (2004) 1.82
Beta-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells. Cancer Res (2003) 1.81
Age-associated change in the frequency of memory CD4+ T cells impairs long term CD4+ T cell responses to influenza vaccine. J Immunol (2004) 1.80
Human neural stem cell grafts ameliorate motor neuron disease in SOD-1 transgenic rats. Transplantation (2006) 1.80
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Efficacy of interferon alpha-2b and ribavirin against West Nile virus in vitro. Emerg Infect Dis (2002) 1.75
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Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation. J Clin Invest (2015) 1.74
Normal magnetic resonance imaging and medial temporal lobe epilepsy: the clinical syndrome of paradoxical temporal lobe epilepsy. J Neurosurg (2005) 1.74
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A case of meningoencephalitis by the relapsing fever spirochaete Borrelia miyamotoi in Europe. Lancet (2013) 1.73
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Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy. Vaccine (2009) 1.72
Protective and therapeutic capacity of human single-chain Fv-Fc fusion proteins against West Nile virus. J Virol (2005) 1.72
Hypoglycemic and hypolipidemic effects and antioxidant activity of fruit extracts from Lycium barbarum. Life Sci (2004) 1.71
IL-10 regulates murine lupus. J Immunol (2002) 1.70
Slowing bacterial translation speed enhances eukaryotic protein folding efficiency. J Mol Biol (2010) 1.70
A West Nile virus recombinant protein vaccine that coactivates innate and adaptive immunity. J Infect Dis (2007) 1.68
Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature (2011) 1.67
Immunoassay targeting nonstructural protein 5 to differentiate West Nile virus infection from dengue and St. Louis encephalitis virus infections and from flavivirus vaccination. J Clin Microbiol (2003) 1.65
Synthesis and electromagnetic, microwave absorbing properties of core-shell Fe3O4-poly(3, 4-ethylenedioxythiophene) microspheres. ACS Appl Mater Interfaces (2011) 1.62
Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation. Nat Immunol (2009) 1.61
Autoantibody induction by DNA-containing immune complexes requires HMGB1 with the TLR2/microRNA-155 pathway. J Immunol (2013) 1.61
Induction of regulatory T cells by physiological level estrogen. J Cell Physiol (2008) 1.59
Detection of human anti-flavivirus antibodies with a west nile virus recombinant antigen microsphere immunoassay. J Clin Microbiol (2004) 1.59
γδT Cell-derived interleukin-17A via an interleukin-1β-dependent mechanism mediates cardiac injury and fibrosis in hypertension. Hypertension (2014) 1.59
Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion. J Clin Invest (2007) 1.57
Disruption of Ixodes scapularis anticoagulation by using RNA interference. Proc Natl Acad Sci U S A (2004) 1.56
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Anaplasma phagocytophilum utilizes multiple host evasion mechanisms to thwart NADPH oxidase-mediated killing during neutrophil infection. Infect Immun (2004) 1.52