Published in Cancer Lett on March 28, 2015
Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis. Semin Cancer Biol (2015) 0.78
MiRNA-543 promotes osteosarcoma cell proliferation and glycolysis by partially suppressing PRMT9 and stabilizing HIF-1α protein. Oncotarget (2016) 0.77
A Switch in Akt Isoforms Is Required for Notch-Induced Snail1 Expression and Protection from Cell Death. Mol Cell Biol (2015) 0.77
Global analysis of H3K27me3 as an epigenetic marker in prostate cancer progression. BMC Cancer (2017) 0.75
Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation. Nat Commun (2017) 0.75
Epithelial-to-Pericyte Transition in Cancer. Cancers (Basel) (2017) 0.75
Epithelial-mesenchymal transitions in development and disease. Cell (2009) 39.17
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer (2007) 18.69
The snail superfamily of zinc-finger transcription factors. Nat Rev Mol Cell Biol (2002) 10.59
Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol (2014) 10.04
A conditional knockout resource for the genome-wide study of mouse gene function. Nature (2011) 9.93
Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol (2004) 9.80
A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature (1998) 8.48
The Snail genes as inducers of cell movement and survival: implications in development and cancer. Development (2005) 8.42
TGFβ signalling in context. Nat Rev Mol Cell Biol (2012) 8.08
Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol (2009) 7.95
Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer (2013) 6.13
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer. Nat Rev Cancer (2008) 6.10
Mechanisms of estrogen action. Physiol Rev (2001) 5.97
A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells. Nat Cell Biol (2006) 4.55
Online survival analysis software to assess the prognostic value of biomarkers using transcriptomic data in non-small-cell lung cancer. PLoS One (2013) 4.31
Adherens junctions: from molecules to morphogenesis. Nat Rev Mol Cell Biol (2010) 3.97
Wnt-dependent regulation of the E-cadherin repressor snail. J Biol Chem (2005) 3.03
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J (2005) 2.72
Mechanisms and function of substrate recruitment by F-box proteins. Nat Rev Mol Cell Biol (2013) 2.56
Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses. Proc Natl Acad Sci U S A (2004) 1.99
The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha. Mol Endocrinol (2007) 1.95
The N-end rule pathway. Annu Rev Biochem (2012) 1.88
SnapShot: F Box Proteins II. Cell (2009) 1.88
FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas. Nature (2012) 1.79
Epithelial E- and P-cadherins: role and clinical significance in cancer. Biochim Biophys Acta (2012) 1.64
A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol (2004) 1.63
Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression. Proc Natl Acad Sci U S A (2012) 1.59
The Snail-like CES-1 protein of C. elegans can block the expression of the BH3-only cell-death activator gene egl-1 by antagonizing the function of bHLH proteins. Development (2003) 1.57
Outside-in signaling through integrins and cadherins: a central mechanism to control epidermal growth and differentiation? J Invest Dermatol (2008) 1.50
E-cadherin controls adherens junctions in the epidermis and the renewal of hair follicles. EMBO J (2003) 1.44
The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein. Mol Cell (1999) 1.44
The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation. J Biol Chem (2009) 1.35
p63: revving up epithelial stem-cell potential. Nat Cell Biol (2007) 1.32
Novel protein domains and repeats in Drosophila melanogaster: insights into structure, function, and evolution. Genome Res (2001) 1.28
DRE-1: an evolutionarily conserved F box protein that regulates C. elegans developmental age. Dev Cell (2007) 1.22
Contact inhibition (of proliferation) redux. Curr Opin Cell Biol (2012) 1.22
The developmental transcription factor slug is widely expressed in tissues of adult mice. J Histochem Cytochem (2004) 1.20
Slug stability is dynamically regulated during neural crest development by the F-box protein Ppa. Development (2006) 1.19
A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse. Hum Mol Genet (2006) 1.13
Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics (2009) 1.08
The skinny on Slug. Mol Carcinog (2010) 1.06
PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis. Cancer Cell (2014) 1.06
CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration. Mol Cell (2013) 1.05
The C. elegans Snail homolog CES-1 can activate gene expression in vivo and share targets with bHLH transcription factors. Nucleic Acids Res (2009) 1.01
Expression of snail in epidermal keratinocytes promotes cutaneous inflammation and hyperplasia conducive to tumor formation. Cancer Res (2010) 0.96
DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation. Dev Cell (2014) 0.92
Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase. Mol Cell (2013) 0.92
Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability. Nucleic Acids Res (2013) 0.90
Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential. Cell Death Differ (2013) 0.89
Slug (Snai2) expression during skin and hair follicle development. J Invest Dermatol (2010) 0.87
Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCF{beta}-TrCP by single substrate depletion. Genes Dev (2010) 0.87
The malignant brain tumor (MBT) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 demethylase complex for chromatin association and epithelial-to-mesenchymal transition. J Biol Chem (2013) 0.84
Keratohyalin, trichohyalin and keratohyalin-trichohyalin hybrid granules: an overview. J Dermatol (1992) 0.81
Coordination of cell proliferation and cell fate determination by CES-1 snail. PLoS Genet (2013) 0.80