Published in Sci Rep on April 30, 2015
Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER. J Cell Biol (2016) 0.90
Formin-mediated actin polymerization at cell-cell junctions stabilizes E-cadherin and maintains monolayer integrity during wound repair. Mol Biol Cell (2016) 0.76
Changes in E-cadherin rigidity sensing regulate cell adhesion. Proc Natl Acad Sci U S A (2017) 0.75
Profilin connects actin assembly with microtubule dynamics. Mol Biol Cell (2016) 0.75
Small-molecule agonists of mammalian Diaphanous-related (mDia) formins reveal an effective glioblastoma anti-invasion strategy. Mol Biol Cell (2015) 0.75
Two Distinct Actin Networks Mediate Traction Oscillations to Confer Focal Adhesion Mechanosensing. Biophys J (2017) 0.75
Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors. Nat Commun (2017) 0.75
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p53 mutations in cancer. Nat Cell Biol (2013) 5.18
Mutant p53 drives invasion by promoting integrin recycling. Cell (2009) 4.75
mDia mediates Rho-regulated formation and orientation of stable microtubules. Nat Cell Biol (2001) 3.71
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Unleashing formins to remodel the actin and microtubule cytoskeletons. Nat Rev Mol Cell Biol (2009) 3.45
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Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy. Methods Enzymol (2004) 3.02
Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria. Nat Genet (2009) 3.01
Functional cooperation between the microtubule and actin cytoskeletons. Curr Opin Cell Biol (2000) 2.95
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nat Cell Biol (2006) 2.93
Microtubules and the organization of the Golgi complex. Exp Cell Res (1985) 2.69
Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly. Chem Biol (2009) 2.57
p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. Nat Cell Biol (2009) 2.35
Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices. J Cell Biol (2007) 2.17
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Regulatory interactions between two actin nucleators, Spire and Cappuccino. J Cell Biol (2007) 2.08
Aurora B regulates formin mDia3 in achieving metaphase chromosome alignment. Dev Cell (2011) 1.98
Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel. Proc Natl Acad Sci U S A (2011) 1.98
The formin mDia2 stabilizes microtubules independently of its actin nucleation activity. J Cell Biol (2008) 1.96
Mutations in the neuronal ß-tubulin subunit TUBB3 result in malformation of cortical development and neuronal migration defects. Hum Mol Genet (2010) 1.83
BRD7 is a candidate tumour suppressor gene required for p53 function. Nat Cell Biol (2010) 1.76
Coordination of microtubule and microfilament dynamics by Drosophila Rho1, Spire and Cappuccino. Nat Cell Biol (2006) 1.65
Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics. Proc Natl Acad Sci U S A (2002) 1.64
p19Arf-p53 tumor suppressor pathway regulates cell motility by suppression of phosphoinositide 3-kinase and Rac1 GTPase activities. J Biol Chem (2003) 1.49
Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep (2012) 1.43
Congenital myopathies: diseases of the actin cytoskeleton. J Pathol (2004) 1.42
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WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2. Nat Cell Biol (2008) 1.38
Analysis of turnover dynamics of the submembranous actin cortex. Mol Biol Cell (2013) 1.38
Differential interactions of the formins INF2, mDia1, and mDia2 with microtubules. Mol Biol Cell (2011) 1.31
Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion. Oncogene (2004) 1.29
Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression. Dev Cell (2011) 1.29
Strong and ubiquitous expression of transgenes targeted into the beta-actin locus by Cre/lox cassette replacement. Genesis (2005) 1.25
Actin microfilaments are essential for the cytological positioning and morphology of the Golgi complex. Eur J Cell Biol (1998) 1.25
α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction. J Cell Biol (2012) 1.22
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Analysis of the local organization and dynamics of cellular actin networks. J Cell Biol (2013) 1.13
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Filamin acts as a key regulator in epithelial defence against transformed cells. Nat Commun (2014) 1.10
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Splice variant-specific cellular function of the formin INF2 in maintenance of Golgi architecture. Mol Biol Cell (2011) 1.07
INF1 is a novel microtubule-associated formin. Mol Biol Cell (2008) 1.04
Golgi as an MTOC: making microtubules for its own good. Histochem Cell Biol (2013) 1.04
Ubiquitin-mediated degradation of the formin mDia2 upon completion of cell division. J Biol Chem (2009) 1.03
FHOD1 is needed for directed forces and adhesion maturation during cell spreading and migration. Dev Cell (2013) 1.03
Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1. Mol Biol Cell (2012) 1.01
Involvement of the Rho-mDia1 pathway in the regulation of Golgi complex architecture and dynamics. Mol Biol Cell (2011) 1.01
Disruption of actin microfilaments by cytochalasin D leads to activation of p53. FEBS Lett (1998) 1.00
Actin coating and compression of fused secretory vesicles are essential for surfactant secretion--a role for Rho, formins and myosin II. J Cell Sci (2012) 1.00
Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2. Exp Cell Res (2006) 0.99
Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces. Cell Rep (2013) 0.98
Identification and functional characterization of FMN2, a regulator of the cyclin-dependent kinase inhibitor p21. Mol Cell (2013) 0.97
Mechanisms of leading edge protrusion in interstitial migration. Nat Commun (2013) 0.97
An optogenetic tool for the activation of endogenous diaphanous-related formins induces thickening of stress fibers without an increase in contractility. Cytoskeleton (Hoboken) (2013) 0.97
Actin recruitment to the Chlamydia inclusion is spatiotemporally regulated by a mechanism that requires host and bacterial factors. PLoS One (2012) 0.95
Nutlin-3a induces cytoskeletal rearrangement and inhibits the migration and invasion capacity of p53 wild-type cancer cells. Mol Cancer Ther (2010) 0.92
Changes in p53 expression in mouse fibroblasts can modify motility and extracellular matrix organization. Oncogene (2000) 0.92
Formation of adherens junctions leads to the emergence of a tissue-level tension in epithelial monolayers. J Cell Sci (2014) 0.90
Control of myofibroblast differentiation by microtubule dynamics through a regulated localization of mDia2. J Biol Chem (2013) 0.89
Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics. Nat Commun (2013) 0.87
AtFH1 formin mutation affects actin filament and microtubule dynamics in Arabidopsis thaliana. J Exp Bot (2012) 0.87
The microtubule end-binding protein EB2 is a central regulator of microtubule reorganisation in apico-basal epithelial differentiation. J Cell Sci (2013) 0.86
Arp2/3 inhibition induces amoeboid-like protrusions in MCF10A epithelial cells by reduced cytoskeletal-membrane coupling and focal adhesion assembly. PLoS One (2014) 0.83
The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology. J Cell Sci (2013) 0.82
Dia-interacting protein (DIP) imposes migratory plasticity in mDia2-dependent tumor cells in three-dimensional matrices. PLoS One (2012) 0.82
Loss of γ-cytoplasmic actin triggers myofibroblast transition of human epithelial cells. Mol Biol Cell (2014) 0.81
An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids. PLoS One (2014) 0.81
Actin polymerization negatively regulates p53 function by impairing its nuclear import in response to DNA damage. PLoS One (2013) 0.80
Small-molecule intramimics of formin autoinhibition: a new strategy to target the cytoskeletal remodeling machinery in cancer cells. Cancer Res (2013) 0.79
RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness. Blood (2014) 0.79
Oncogenic Shp2 disturbs microtubule regulation to cause HDAC6-dependent ERK hyperactivation. Oncogene (2013) 0.76
Proteomic analyses uncover a new function and mode of action for mouse homolog of Diaphanous 2 (mDia2). Mol Cell Proteomics (2015) 0.76