Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.

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Published in Hum Mol Genet on February 09, 2016

Authors

David A Hinds1, Alfonso Buil2, Daniel Ziemek3, Angel Martinez-Perez4, Rainer Malik5, Lasse Folkersen6, Marine Germain7, Anders Mälarstig3, Andrew Brown2, Jose Manuel Soria4, Martin Dichgans8, Nan Bing9, Anders Franco-Cereceda10, Juan Carlos Souto11, Emmanouil T Dermitzakis2, Anders Hamsten12, Bradford B Worrall13, Joyce Y Tung1, METASTROKE Consortium, INVENT Consortium, Maria Sabater-Lleal14

Author Affiliations

1: 23andMe, Inc., Mountain View, CA, USA.
2: Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
3: Pfizer Worldwide R&D, New York, NY, USA, Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
4: Unitat de Genòmica de Malalties Complexes (UGMC), Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, Barcelona, Spain.
5: Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians Universität, Munich, Germany.
6: Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Building 208, DK-2800 Kongens Lyngby, Denmark.
7: Sorbonne Universités, UPMC Univ Paris 06, INSERM UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases ICAN Institute for Cardiometabolism and Nutrition, Paris, France.
8: Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians University, Munich, Germany, Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
9: Pfizer Worldwide R&D, New York, NY, USA.
10: Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.
11: Unitat d'Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, Barcelona, Spain and.
12: Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
13: Department of Neurology, University of Virginia Health System, Charlottesville, VA, USA.
14: Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, maria.sabater.lleal@ki.se.

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