Published in Front Physiol on February 16, 2016
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Actin dynamics control SRF activity by regulation of its coactivator MAL. Cell (2003) 7.43
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell (2012) 6.80
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell (2003) 6.48
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis. Mol Cell (2003) 5.66
Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol (2009) 5.41
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Yap1 acts downstream of α-catenin to control epidermal proliferation. Cell (2011) 4.85
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell (2009) 4.81
A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J (1999) 4.66
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev Cell (2010) 4.59
The kinase domain of titin controls muscle gene expression and protein turnover. Science (2005) 3.68
Signaling in muscle atrophy and hypertrophy. Physiology (Bethesda) (2008) 3.68
Restriction of intestinal stem cell expansion and the regenerative response by YAP. Nature (2012) 3.54
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes Dev (2012) 3.48
SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton. Mol Cell Biol (2006) 3.39
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nat Cell Biol (2009) 3.26
A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors. Cell (2013) 3.17
YAP regulates neural progenitor cell number via the TEA domain transcription factor. Genes Dev (2008) 3.16
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Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65. Mol Cell Biol (2006) 3.15
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Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat Rev Mol Cell Biol (2012) 3.07
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Force transduction by Triton cytoskeletons. J Cell Biol (2002) 2.83
Hippo pathway effector Yap promotes cardiac regeneration. Proc Natl Acad Sci U S A (2013) 2.76
Modulating F-actin organization induces organ growth by affecting the Hippo pathway. EMBO J (2011) 2.75
Structure and function of the WW domain. Prog Biophys Mol Biol (1996) 2.73
E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components. Proc Natl Acad Sci U S A (2011) 2.61
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YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29. Nat Cell Biol (2012) 2.59
Mechanical memory and dosing influence stem cell fate. Nat Mater (2014) 2.50
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Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size. Sci Signal (2011) 2.38
Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus. Nat Cell Biol (2014) 2.30
Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila. Development (2011) 2.20
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2. Cell (2013) 2.16
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A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling. EMBO J (2012) 1.81
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Conversion of mechanical force into TGF-β-mediated biochemical signals. Curr Biol (2011) 1.74
The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1. EMBO J (2007) 1.69
Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1. Proc Natl Acad Sci U S A (2013) 1.59
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Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation. J Biol Chem (2007) 1.35
In vitro model for stretch-induced hypertrophy of skeletal muscle. Science (1979) 1.33
Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP. Dev Biol (2012) 1.32
Disease implications of the Hippo/YAP pathway. Trends Mol Med (2015) 1.32
The Hippo-YAP signaling pathway and contact inhibition of growth. J Cell Sci (2014) 1.29
YAP and TAZ: a nexus for Hippo signaling and beyond. Trends Cell Biol (2015) 1.29
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The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin. Mol Biol Cell (2003) 1.24
Alternative Wnt Signaling Activates YAP/TAZ. Cell (2015) 1.21
Regulation of the Hippo pathway by cell architecture and mechanical signals. Semin Cell Dev Biol (2012) 1.20
Akt signaling in skeletal muscle: regulation by exercise and passive stretch. Am J Physiol Endocrinol Metab (2003) 1.20
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Intracellular signaling specificity in response to uniaxial vs. multiaxial stretch: implications for mechanotransduction. Am J Physiol Cell Physiol (2004) 1.14
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis. Genes Dev (2015) 1.13
Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function. Biochem Soc Trans (2011) 1.11
The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation. Cancer Cell (2014) 1.11
Mechanotransduction in bone repair and regeneration. FASEB J (2010) 1.10
Yap is a novel regulator of C2C12 myogenesis. Biochem Biophys Res Commun (2010) 1.10
Mechanisms of muscle growth and atrophy in mammals and Drosophila. Dev Dyn (2013) 1.09
Skeletal muscle wasting with disuse atrophy is multi-dimensional: the response and interaction of myonuclei, satellite cells and signaling pathways. Front Physiol (2014) 1.08
Mechanotransduction and the regulation of protein synthesis in skeletal muscle. Proc Nutr Soc (2004) 1.07
Yes-associated protein 65 (YAP) expands neural progenitors and regulates Pax3 expression in the neural plate border zone. PLoS One (2011) 1.05
Transcription factor TEAD4 regulates expression of myogenin and the unfolded protein response genes during C2C12 cell differentiation. Cell Death Differ (2011) 1.04
The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells. J Cell Sci (2012) 1.04
Myostatin and the skeletal muscle atrophy and hypertrophy signaling pathways. Cell Mol Life Sci (2014) 1.03
Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression. J Clin Invest (2013) 1.02
Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration. Sci Signal (2014) 0.98
Regulation of mammalian Ste20 (Mst) kinases. Trends Biochem Sci (2015) 0.98
YAP and TAZ, Hippo signaling targets, act as a rheostat for nuclear SHP2 function. Dev Cell (2013) 0.96
The Hippo signal transduction network in skeletal and cardiac muscle. Sci Signal (2014) 0.96