Published in J Cell Biol on July 18, 2016
Cell migration: integrating signals from front to back. Science (2003) 29.13
Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nat Rev Mol Cell Biol (2010) 7.27
Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature (2010) 6.25
Integrins regulate Rac targeting by internalization of membrane domains. Science (2004) 5.07
Mechanotransduction in vascular physiology and atherogenesis. Nat Rev Mol Cell Biol (2009) 4.58
Mechanisms of mechanotransduction. Dev Cell (2006) 3.95
Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments. Dev Cell (2007) 3.84
Dynamic molecular processes mediate cellular mechanotransduction. Nature (2011) 3.38
Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway. Dev Cell (2005) 3.26
Integrin-dependent actomyosin contraction regulates epithelial cell scattering. J Cell Biol (2005) 3.20
Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth. Cancer Cell (2011) 3.19
Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization. Nat Cell Biol (2005) 3.13
Rapid signal transduction in living cells is a unique feature of mechanotransduction. Proc Natl Acad Sci U S A (2008) 3.04
The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. EMBO J (2009) 2.76
Ultrafast long-range charge separation in organic semiconductor photovoltaic diodes. Science (2013) 2.37
ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation. Cell Stem Cell (2013) 2.32
Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization. Dev Cell (2009) 2.32
Polyene-lipids: a new tool to image lipids. Nat Methods (2004) 2.30
Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution. PLoS One (2011) 2.29
The Structure of the talin head reveals a novel extended conformation of the FERM domain. Structure (2010) 2.22
Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biol (2009) 2.16
Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Curr Biol (2013) 2.02
In vivo dynamics of Rac-membrane interactions. Mol Biol Cell (2006) 1.95
Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis. J Cell Biol (2003) 1.93
Integrin-mediated adhesion regulates membrane order. J Cell Biol (2006) 1.92
N-WASP deficiency impairs EGF internalization and actin assembly at clathrin-coated pits. J Cell Sci (2005) 1.89
Optical coherence tomography today: speed, contrast, and multimodality. J Biomed Opt (2014) 1.79
LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. J Cell Biol (2010) 1.79
Rho mediates the shear-enhancement of endothelial cell migration and traction force generation. Biophys J (2004) 1.77
The structure of the C-terminal actin-binding domain of talin. EMBO J (2007) 1.77
Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins. Nat Cell Biol (2002) 1.76
Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice. Arterioscler Thromb Vasc Biol (2008) 1.76
Nanometer targeting of microtubules to focal adhesions. J Cell Biol (2003) 1.69
Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J (2007) 1.69
Catheter ablation vs antiarrhythmic drug therapy for atrial fibrillation: a systematic review. Arch Intern Med (2008) 1.68
Matrix-specific suppression of integrin activation in shear stress signaling. Mol Biol Cell (2006) 1.67
High-resolution synthetic-aperture digital holography with digital phase and pupil correction. Opt Express (2011) 1.64
Siah1/SIP regulates p27(kip1) stability and cell migration under metabolic stress. Cell Cycle (2011) 1.59
Adaptor functions of Cdc42, Ste50, and Sho1 in the yeast osmoregulatory HOG MAPK pathway. EMBO J (2006) 1.55
Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery. Nat Struct Mol Biol (2011) 1.53
Readability assessment of internet-based patient education materials related to uterine artery embolization. J Vasc Interv Radiol (2013) 1.50
Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53. Cancer Res (2011) 1.44
12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB. Arterioscler Thromb Vasc Biol (2005) 1.41
VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function. J Biol Chem (2004) 1.38
Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels. Proc Natl Acad Sci U S A (2012) 1.38
Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway. J Cell Biol (2009) 1.36
Structural determinants of integrin binding to the talin rod. J Biol Chem (2009) 1.35
A complex between FAK, RACK1, and PDE4D5 controls spreading initiation and cancer cell polarity. Curr Biol (2010) 1.34
The innate growth bistability and fitness landscapes of antibiotic-resistant bacteria. Science (2013) 1.34
Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation. Circ Res (2010) 1.29
Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1. Eur J Cell Biol (2010) 1.29
The role of cellular adaptation to mechanical forces in atherosclerosis. Arterioscler Thromb Vasc Biol (2008) 1.28
The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging. PLoS Comput Biol (2008) 1.27
Recent advances using green and red fluorescent protein variants. Appl Microbiol Biotechnol (2007) 1.27
Real-time study of E-cadherin and membrane dynamics in living animals: implications for disease modeling and drug development. Cancer Res (2009) 1.25
Long-range mechanical force enables self-assembly of epithelial tubular patterns. Proc Natl Acad Sci U S A (2012) 1.24
Cell geometric constraints induce modular gene-expression patterns via redistribution of HDAC3 regulated by actomyosin contractility. Proc Natl Acad Sci U S A (2013) 1.22
Central region of talin has a unique fold that binds vinculin and actin. J Biol Chem (2010) 1.21
Substrate rigidity regulates Ca2+ oscillation via RhoA pathway in stem cells. J Cell Physiol (2009) 1.21
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. Cancer Res (2009) 1.21
Integrins in mechanotransduction. Curr Opin Cell Biol (2013) 1.21
Rapid activation of Rac GTPase in living cells by force is independent of Src. PLoS One (2009) 1.20
Gallium-68-DOTA-NOC PET/CT of patients with gastroenteropancreatic neuroendocrine tumors: a prospective single-center study. AJR Am J Roentgenol (2011) 1.20
Regulation of LKB1/STRAD localization and function by E-cadherin. Curr Biol (2008) 1.18
Visualization of Src activity at different compartments of the plasma membrane by FRET imaging. Chem Biol (2009) 1.18
Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function. Proc Natl Acad Sci U S A (2009) 1.17
Quantitative dynamic footprinting microscopy reveals mechanisms of neutrophil rolling. Nat Methods (2010) 1.17
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor. Genes Dev (2011) 1.17
Inhibition of autophagy impairs tumor cell invasion in an organotypic model. Cell Cycle (2012) 1.14
The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study. Structure (2010) 1.14
The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly. EMBO Rep (2010) 1.14
Src and caveolin-1 reciprocally regulate metastasis via a common downstream signaling pathway in bladder cancer. Cancer Res (2010) 1.14
Rac, membrane heterogeneity, caveolin and regulation of growth by integrins. Trends Cell Biol (2007) 1.13
Matrix metalloproteinase inhibitors as prospective agents for the prevention and treatment of cardiovascular and neoplastic diseases. Curr Top Med Chem (2006) 1.12
Rho-ROCK-LIMK-cofilin pathway regulates shear stress activation of sterol regulatory element binding proteins. Circ Res (2003) 1.11
Mechanically induced actin-mediated rocketing of phagosomes. Mol Biol Cell (2006) 1.10
Need-based activation of ammonium uptake in Escherichia coli. Mol Syst Biol (2012) 1.10
Lessons from the endothelial junctional mechanosensory complex. F1000 Biol Rep (2012) 1.08
Bilateral gynecomastia: A rare presentation of thyrotoxicosis. Indian J Endocrinol Metab (2013) 1.07
The leading edge is a lipid diffusion barrier. J Cell Sci (2005) 1.07
A novel interaction between FRMD7 and CASK: evidence for a causal role in idiopathic infantile nystagmus. Hum Mol Genet (2013) 1.07
Endothelial-to-mesenchymal transition drives atherosclerosis progression. J Clin Invest (2015) 1.06
Endothelial nuclear factor-κB-dependent regulation of arteriogenesis and branching. Circulation (2012) 1.06
Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer. Nat Commun (2011) 1.06
Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes. FEBS Lett (2005) 1.05
Subcellular localization of talin is regulated by inter-domain interactions. J Biol Chem (2012) 1.05
Clinical relevance of palmaris longus agenesis: common anatomical aberration. Anat Sci Int (2008) 1.03
A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration. J Biol Chem (2002) 1.03
Enzymatic properties of rat myelencephalon-specific protease. Biochemistry (2002) 1.03
⁶⁸Ga-DOTANOC PET/CT in patients with carcinoma of unknown primary of neuroendocrine origin. Clin Nucl Med (2012) 1.02
The regulation of dynamic mechanical coupling between actin cytoskeleton and nucleus by matrix geometry. Biomaterials (2013) 1.02
Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration. Am J Respir Crit Care Med (2007) 1.01
Dynamic control of yeast MAP kinase network by induced association and dissociation between the Ste50 scaffold and the Opy2 membrane anchor. Mol Cell (2010) 1.00
Transcriptome sequencing and de novo annotation of the critically endangered Adriatic sturgeon. BMC Genomics (2013) 1.00
Flow-dependent cellular mechanotransduction in atherosclerosis. J Cell Sci (2013) 1.00
Organotypic collagen I assay: a malleable platform to assess cell behaviour in a 3-dimensional context. J Vis Exp (2011) 0.99
Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of src in pancreatic cancer. Cancer Res (2013) 0.99
The intermediate S1' pocket of the endometase/matrilysin-2 active site revealed by enzyme inhibition kinetic studies, protein sequence analyses, and homology modeling. J Biol Chem (2003) 0.98