Sepsis in Pediatric Cardiac Intensive Care.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27490609)

Published in Pediatr Crit Care Med on August 01, 2016

Authors

Derek S Wheeler1, Hector R Wong

Author Affiliations

1: Both authors: Department of Pediatrics, Section of Critical Care Medicine, Cincinnati College of Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Articles cited by this

Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med (2001) 51.99

Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet (2010) 26.48

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med (1992) 20.79

A randomized trial of protocol-based care for early septic shock. N Engl J Med (2014) 16.05

International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med (2005) 13.40

Goal-directed resuscitation for patients with early septic shock. N Engl J Med (2014) 11.32

Trial of early, goal-directed resuscitation for septic shock. N Engl J Med (2015) 8.24

Systemic inflammatory response syndrome criteria in defining severe sepsis. N Engl J Med (2015) 7.73

Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine. Crit Care Med (2009) 7.55

The epidemiology of severe sepsis in children in the United States. Am J Respir Crit Care Med (2002) 4.72

Profound but reversible myocardial depression in patients with septic shock. Ann Intern Med (1984) 3.81

Early reversal of pediatric-neonatal septic shock by community physicians is associated with improved outcome. Pediatrics (2003) 3.49

Clinical practice parameters for hemodynamic support of pediatric and neonatal patients in septic shock. Crit Care Med (2002) 3.41

Surviving Sepsis Campaign: association between performance metrics and outcomes in a 7.5-year study. Crit Care Med (2015) 2.81

Multimodal monitoring for hemodynamic categorization and management of pediatric septic shock: a pilot observational study*. Pediatr Crit Care Med (2014) 2.72

Hemodynamic changes in preterm neonates with septic shock: a prospective observational study*. Pediatr Crit Care Med (2014) 2.65

Pediatric severe sepsis in U.S. children's hospitals. Pediatr Crit Care Med (2014) 2.43

ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation. Intensive Care Med (2008) 2.40

A myocardial cytotoxic process is involved in the cardiac dysfunction of meningococcal septic shock. Crit Care Med (2000) 2.35

Proof of principle: the predisposition, infection, response, organ failure sepsis staging system. Crit Care Med (2011) 2.30

A circulating myocardial depressant substance in humans with septic shock. Septic shock patients with a reduced ejection fraction have a circulating factor that depresses in vitro myocardial cell performance. J Clin Invest (1985) 2.26

Identification of pediatric septic shock subclasses based on genome-wide expression profiling. BMC Med (2009) 2.23

Validation of a gene expression-based subclassification strategy for pediatric septic shock. Crit Care Med (2011) 2.20

Developing a clinically feasible personalized medicine approach to pediatric septic shock. Am J Respir Crit Care Med (2015) 2.09

Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and therapies study. Am J Respir Crit Care Med (2015) 2.09

Biomarker discovery and development in pediatric critical care medicine. Pediatr Crit Care Med (2011) 2.08

The pediatric sepsis biomarker risk model. Crit Care (2012) 1.99

Epidemiology of sepsis and multiple organ dysfunction syndrome in children. Chest (1996) 1.96

Steroid use before pediatric cardiac operations using cardiopulmonary bypass: an international survey of 36 centers. Pediatr Crit Care Med (2005) 1.93

Endotoxin tolerance: is there a clinical relevance? J Endotoxin Res (2003) 1.87

Delayed antimicrobial therapy increases mortality and organ dysfunction duration in pediatric sepsis. Crit Care Med (2014) 1.81

Do outcomes vary according to the source of admission to the pediatric intensive care unit? Pediatr Crit Care Med (2008) 1.74

Post-ICU admission fluid balance and pediatric septic shock outcomes: a risk-stratified analysis. Crit Care Med (2014) 1.72

Functional outcomes in pediatric severe sepsis: further analysis of the researching severe sepsis and organ dysfunction in children: a global perspective trial. Pediatr Crit Care Med (2013) 1.70

Two-dimensional speckle tracking imaging detects impaired myocardial performance in children with septic shock, not recognized by conventional echocardiography. Pediatr Crit Care Med (2012) 1.69

Increases in serum levels of troponin I are associated with cardiac dysfunction and disease severity in pediatric patients with septic shock. Pediatr Crit Care Med (2004) 1.69

Early postoperative monocyte deactivation predicts systemic inflammation and prolonged stay in pediatric cardiac intensive care. Crit Care Med (2002) 1.68

The host response to sepsis and developmental impact. Pediatrics (2010) 1.62

Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept. Crit Care Med (2010) 1.51

Defining pediatric sepsis by different criteria: discrepancies in populations and implications for clinical practice. Pediatr Crit Care Med (2012) 1.51

Persistent preload defect in severe sepsis despite fluid loading: A longitudinal echocardiographic study in patients with septic shock. Chest (1999) 1.46

Predisposition, insult/infection, response, and organ dysfunction: A new model for staging severe sepsis. Crit Care Med (2009) 1.39

Right ventricular dysfunction and dilatation, similar to left ventricular changes, characterize the cardiac depression of septic shock in humans. Chest (1990) 1.38

Readmission and late mortality after pediatric severe sepsis. Pediatrics (2009) 1.38

An emergency department septic shock protocol and care guideline for children initiated at triage. Pediatrics (2011) 1.37

Interleukin-10 and its role in clinical immunoparalysis following pediatric cardiac surgery. Crit Care Med (2006) 1.35

Implementation of goal-directed therapy for children with suspected sepsis in the emergency department. Pediatrics (2011) 1.34

Hemodynamic patterns of meningococcal shock in children. Crit Care Med (1988) 1.31

Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children. Crit Care (2012) 1.31

Hemodynamic support in fluid-refractory pediatric septic shock. Pediatrics (1998) 1.29

Nosocomial infections after cardiac surgery in infants and children: incidence and risk factors. J Hosp Infect (2003) 1.23

The relationship between inflammatory activation and clinical outcome after infant cardiopulmonary bypass. Anesth Analg (2010) 1.23

Testing the prognostic accuracy of the updated pediatric sepsis biomarker risk model. PLoS One (2014) 1.22

Sepsis-induced cardiomyopathy. Curr Cardiol Rev (2011) 1.21

Sepsis-induced cardiomyopathy: a review of pathophysiologic mechanisms. Heart Fail Rev (2010) 1.18

Critical decision method: a technique for eliciting concrete assessment indicators from the intuition of NICU nurses. ANS Adv Nurs Sci (1993) 1.14

Risk factors for sternal wound and other infections in pediatric cardiac surgery patients. Pediatr Infect Dis J (2000) 1.14

Novel pharmacologic approaches to the management of sepsis: targeting the host inflammatory response. Recent Pat Inflamm Allergy Drug Discov (2009) 1.14

Corticosteroids and pediatric septic shock outcomes: a risk stratified analysis. PLoS One (2014) 1.13

Cardiac performance and mortality early after intracardiac surgery in infants and young children. Circulation (1975) 1.12

Depressed left ventricular performance. Response to volume infusion in patients with sepsis and septic shock. Chest (1988) 1.09

Reducing catheter-associated bloodstream infections in the pediatric intensive care unit: Business case for quality improvement. Pediatr Crit Care Med (2010) 1.08

Distributions of cardiopulmonary variables in pediatric survivors and nonsurvivors of septic shock. Crit Care Med (1985) 1.06

Right ventricular performance in septic shock: a combined radionuclide and hemodynamic study. J Am Coll Cardiol (1984) 1.03

The temporal version of the pediatric sepsis biomarker risk model. PLoS One (2014) 1.02

Biomarkers of sepsis and their potential value in diagnosis, prognosis and treatment. Expert Rev Clin Immunol (2014) 1.01

The business case for preventing ventilator-associated pneumonia in pediatric intensive care unit patients. Jt Comm J Qual Patient Saf (2008) 1.00

Clinical implications and molecular mechanisms of immunoparalysis after cardiopulmonary bypass. J Thorac Cardiovasc Surg (2011) 1.00

Pediatric cardiac surgery with cardiopulmonary bypass: pathways contributing to transient systemic immune suppression. Shock (2001) 0.99

Myocardial depression in sepsis: from pathogenesis to clinical manifestations and treatment. J Crit Care (2014) 0.98

The pediatric sepsis biomarker risk model: potential implications for sepsis therapy and biology. Expert Rev Anti Infect Ther (2014) 0.98

Interleukin 27 as a sepsis diagnostic biomarker in critically ill adults. Shock (2013) 0.98

Early nosocomial infections in pediatric cardiovascular surgery patients. Crit Care Med (1990) 0.98

Perioperative steroids administration in pediatric cardiac surgery: a meta-analysis of randomized controlled trials*. Pediatr Crit Care Med (2014) 0.96

Improving adherence to PALS septic shock guidelines. Pediatrics (2014) 0.96

Right ventricular dysfunction in septic shock: assessment by measurements of right ventricular ejection fraction using the thermodilution technique. Acta Anaesthesiol Scand (1989) 0.96

Characterization of cardiac dysfunction in sepsis: an ongoing challenge. Shock (2014) 0.95

Impact of bloodstream infection on the outcome of children undergoing cardiac surgery. Pediatr Cardiol (2010) 0.94

Differences between adult and pediatric septic shock. Minerva Anestesiol (2011) 0.94

Factors prolonging length of stay in the cardiac intensive care unit following the arterial switch operation. Cardiol Young (2007) 0.93

Sepsis: going to the heart of the matter. Pathobiology (2012) 0.92

Nosocomial infections after pediatric cardiac surgery. Am J Infect Control (2008) 0.92

Left ventricular failure complicating severe pediatric burn injuries. J Pediatr Surg (1995) 0.91

Financial impact of failing to prevent surgical site infections. Qual Manag Health Care (2007) 0.90

Sequential cardiopulmonary variables of infants and children in septic shock. Crit Care Med (1984) 0.90

Sepsis in the pediatric cardiac intensive care unit. World J Pediatr Congenit Heart Surg (2011) 0.90

Quantitated left ventricular systolic mechanics in children with septic shock utilizing noninvasive wall-stress analysis. Crit Care Med (1994) 0.88

Evolution of haemodynamics and outcome of fluid-refractory septic shock in children. Intensive Care Med (2013) 0.88

A review of sepsis-induced cardiomyopathy. J Intensive Care (2015) 0.88

Pediatric Sepsis - Part I: "Children are not small adults!" Open Inflamm J (2011) 0.87

Age-related variations of left ventricular endocardial and midwall function in healthy infants, children, and adolescents. Ital Heart J (2005) 0.85

The prevalence and diagnostic utility of systemic inflammatory response syndrome vital signs in a pediatric emergency department. Acad Emerg Med (2015) 0.81

L-type Ca2+ channel function and expression in neonatal rabbit ventricular myocytes. Am J Physiol Heart Circ Physiol (2005) 0.79

Myocardial dysfunction in pediatric septic shock. J Pediatr (2013) 0.79

Age-related variation in left ventricular myocardial contractile state expressed by the stress velocity relation. Pediatr Cardiol (1999) 0.77

Prevention of sepsis in children: a new paradigm for public policy. Crit Care Res Pract (2011) 0.77

Pediatric sepsis: preparing for the future against a global scourge. Curr Infect Dis Rep (2012) 0.76

Articles by these authors

(truncated to the top 100)

Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock. Mol Med (2007) 2.58

Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock. Crit Care Med (2008) 2.32

Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis. Crit Care Med (2003) 2.25

Metabolomics as a novel approach for early diagnosis of pediatric septic shock and its mortality. Am J Respir Crit Care Med (2013) 2.14

A novel role for matrix metalloproteinase-8 in sepsis. Crit Care Med (2012) 2.11

Biomarker discovery and development in pediatric critical care medicine. Pediatr Crit Care Med (2011) 2.08

The pediatric sepsis biomarker risk model. Crit Care (2012) 1.99

Validating the genomic signature of pediatric septic shock. Physiol Genomics (2008) 1.96

Admission angiopoietin levels in children with septic shock. Shock (2007) 1.82

Extracellular hsp70 levels in children with septic shock. Pediatr Crit Care Med (2005) 1.79

Zinc homeostasis in pediatric critical illness. Pediatr Crit Care Med (2009) 1.77

Post-ICU admission fluid balance and pediatric septic shock outcomes: a risk-stratified analysis. Crit Care Med (2014) 1.72

A survey of stated physician practices and beliefs on the use of steroids in pediatric fluid and/or vasoactive infusion-dependent shock. Pediatr Crit Care Med (2013) 1.63

The host response to sepsis and developmental impact. Pediatrics (2010) 1.62

Plasma interleukin-8 is not an effective risk stratification tool for adults with vasopressor-dependent septic shock. Crit Care Med (2010) 1.60

Sesquiterpene lactone parthenolide, an inhibitor of IkappaB kinase complex and nuclear factor-kappaB, exerts beneficial effects in myocardial reperfusion injury. Shock (2002) 1.59

The influence of developmental age on the early transcriptomic response of children with septic shock. Mol Med (2011) 1.57

Admission chemokine (C-C motif) ligand 4 levels predict survival in pediatric septic shock. Pediatr Crit Care Med (2010) 1.57

Time for a neonatal-specific consensus definition for sepsis. Pediatr Crit Care Med (2014) 1.56

Extracellular heat shock protein-70 induces endotoxin tolerance in THP-1 cells. J Immunol (2006) 1.55

Lung injury after hemorrhage is age dependent: role of peroxisome proliferator-activated receptor gamma. Crit Care Med (2009) 1.55

Induction of endotoxin tolerance enhances bacterial clearance and survival in murine polymicrobial sepsis. Shock (2008) 1.48

Genetic association research: understanding its challenges and limitations. Pediatr Crit Care Med (2010) 1.46

The PICU perspective on monitoring hemodynamics and oxygen transport. Pediatr Crit Care Med (2011) 1.46

Glucocorticoid Receptor Expression in Peripheral WBCs of Critically Ill Children. Pediatr Crit Care Med (2015) 1.41

Adaptation and increased susceptibility to infection associated with constitutive expression of misfolded SP-C. J Cell Biol (2006) 1.41

Hsp72 induces inflammation and regulates cytokine production in airway epithelium through a TLR4- and NF-kappaB-dependent mechanism. J Immunol (2007) 1.40

The myeloid transcription factor KLF2 regulates the host response to polymicrobial infection and endotoxic shock. Immunity (2011) 1.39

Nuclear factor-kappaB as a therapeutic target in critical care medicine. Crit Care Med (2003) 1.33

Interleukin-27 is a novel candidate diagnostic biomarker for bacterial infection in critically ill children. Crit Care (2012) 1.31

Heat shock response and acute lung injury. Free Radic Biol Med (2006) 1.29

Hepatocyte NF-kappaB activation is hepatoprotective during ischemia-reperfusion injury and is augmented by ischemic hypothermia. Am J Physiol Gastrointest Liver Physiol (2006) 1.28

Contribution of MKP-1 regulation of p38 to endotoxin tolerance. Shock (2005) 1.28

Biomarkers for pediatric sepsis and septic shock. Expert Rev Anti Infect Ther (2011) 1.27

Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents. Mol Pharmacol (2002) 1.23

Pediatric septic shock treatment: new clues from genomic profiling. Pharmacogenomics (2007) 1.22

Mechanisms and regulation of the gene-expression response to sepsis. Pediatrics (2010) 1.22

Pediatric sepsis: challenges and adjunctive therapies. Crit Care Clin (2013) 1.19

Role of biomarkers in sepsis care. Shock (2013) 1.19

Pathophysiology and treatment of septic shock in neonates. Clin Perinatol (2010) 1.17

Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray. Crit Care (2011) 1.16

Absence of inducible nitric oxide synthase modulates early reperfusion-induced NF-kappaB and AP-1 activation and enhances myocardial damage. FASEB J (2002) 1.16

Incorporation of biomarkers with the renal angina index for prediction of severe AKI in critically ill children. Clin J Am Soc Nephrol (2014) 1.15

Novel pharmacologic approaches to the management of sepsis: targeting the host inflammatory response. Recent Pat Inflamm Allergy Drug Discov (2009) 1.14

Epigallocatechin, a green tea polyphenol, attenuates myocardial ischemia reperfusion injury in rats. Mol Med (2004) 1.12

Plasma angiopoietin-2 levels increase in children following cardiopulmonary bypass. Intensive Care Med (2008) 1.10

The A2A receptor mediates an endogenous regulatory pathway of cytokine expression in THP-1 cells. J Leukoc Biol (2002) 1.07

Activation of hepatocytes by extracellular heat shock protein 72. Am J Physiol Cell Physiol (2008) 1.07

Theaflavin, a black tea extract, is a novel anti-inflammatory compound. Crit Care Med (2004) 1.06

Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4. Respir Res (2009) 1.05

Therapeutic effect of epigallocatechin-3-gallate in a mouse model of colitis. Eur J Pharmacol (2007) 1.04

Epigallocatechin-3-gallate, a green tea-derived polyphenol, inhibits IL-1 beta-dependent proinflammatory signal transduction in cultured respiratory epithelial cells. J Nutr (2004) 1.04

A green tea-derived polyphenol, epigallocatechin-3-gallate, inhibits IkappaB kinase activation and IL-8 gene expression in respiratory epithelium. Inflammation (2002) 1.01

Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: role of nuclear factor-kappaB, heat shock factor 1, and Akt. Shock (2007) 1.01

Role of heat shock protein 70 in hepatic ischemia-reperfusion injury in mice. Am J Physiol Gastrointest Liver Physiol (2006) 1.01

Biomarkers of sepsis and their potential value in diagnosis, prognosis and treatment. Expert Rev Clin Immunol (2014) 1.01

Identifying critically ill patients who may benefit from adjunctive corticosteroids: not as easy as we thought. Pediatr Crit Care Med (2014) 1.00

Reduced peroxisome proliferator-activated receptor α expression is associated with decreased survival and increased tissue bacterial load in sepsis. Shock (2012) 0.99

Glutamine's protection against cellular injury is dependent on heat shock factor-1. Am J Physiol Cell Physiol (2006) 0.98

The pediatric sepsis biomarker risk model: potential implications for sepsis therapy and biology. Expert Rev Anti Infect Ther (2014) 0.98

Decompressive abdominal laparotomy for abdominal compartment syndrome in an unengrafted bone marrow recipient with septic shock. Crit Care Res Pract (2010) 0.96

Heat shock inhibits tnf-induced ICAM-1 expression in human endothelial cells via I kappa kinase inhibition. Shock (2002) 0.95

Interactions between the heat shock response and the nuclear factor-kappa B signaling pathway. Crit Care Med (2002) 0.94

Intestine-Derived Matrix Metalloproteinase-8 Is a Critical Mediator of Polymicrobial Peritonitis. Crit Care Med (2016) 0.94

Sepsis in the pediatric cardiac intensive care unit. World J Pediatr Congenit Heart Surg (2011) 0.90

Proteasome inhibitors induce heat shock response and increase IL-6 expression in human intestinal epithelial cells. Am J Physiol Regul Integr Comp Physiol (2002) 0.90

Age-related decrease in proteasome expression contributes to defective nuclear factor-kappaB activation during hepatic ischemia/reperfusion. Hepatology (2009) 0.89

Plasmapheresis to treat hypertriglyceridemia in a child with diabetic ketoacidosis and pancreatitis. Pediatrics (2011) 0.89

PP2A regulates upstream members of the c-jun N-terminal kinase mitogen-activated protein kinase signaling pathway. Shock (2008) 0.89

Selectively increasing inducible heat shock protein 70 via TAT-protein transduction protects neurons from nitrosative stress and excitotoxicity. J Neurochem (2005) 0.89

Differential regulation of activator protein-1 and heat shock factor-1 in myocardial ischemia and reperfusion injury: role of poly(ADP-ribose) polymerase-1. Am J Physiol Heart Circ Physiol (2003) 0.89

CpG DNA modulates interleukin 1beta-induced interleukin-8 expression in human bronchial epithelial (16HBE14o-) cells. Respir Res (2006) 0.89

The role of endogenously produced extracellular hsp72 in mononuclear cell reprogramming. Shock (2008) 0.87

Pediatric Sepsis - Part I: "Children are not small adults!" Open Inflamm J (2011) 0.87

Proteasome inhibitors induce inhibitory kappa B (I kappa B) kinase activation, I kappa B alpha degradation, and nuclear factor kappa B activation in HT-29 cells. Mol Pharmacol (2004) 0.87

Corticosteroids in Pediatric Shock: A Call to Arms. Pediatr Crit Care Med (2015) 0.87

The green tea polyphenol epigallocatechin-3-gallate improves systemic hemodynamics and survival in rodent models of polymicrobial sepsis. Shock (2007) 0.86

Molecular genetics in the pediatric intensive care unit. Crit Care Clin (2003) 0.86

Heat shock inhibits activation of NF-kappaB in the absence of heat shock factor-1. Biochem Biophys Res Commun (2002) 0.85

Mast cell activation is differentially affected by heat shock. Exp Hematol (2005) 0.85

Prophylactic zinc supplementation reduces bacterial load and improves survival in a murine model of sepsis. Pediatr Crit Care Med (2012) 0.85

Temporal and mechanistic effects of heat shock on LPS-mediated degradation of IkappaBalpha in macrophages. Inflammation (2002) 0.84

Acetylsalicylic acid-induced release of HSP70 from mast cells results in cell activation through TLR pathway. Exp Hematol (2006) 0.83

Inhaled nitric oxide increases endothelin-1 levels: a potential cause of rebound pulmonary hypertension. Crit Care Med (2002) 0.83

The United States critical illness and injury trials group: an introduction. J Trauma (2009) 0.83

Ablation of the heat shock factor-1 increases susceptibility to hyperoxia-mediated cellular injury. Exp Lung Res (2002) 0.82

A Cohort Study of Pediatric Shock: Frequency of Corticosteriod Use and Association with Clinical Outcomes. Shock (2015) 0.82

Combined zinc supplementation with proinsulin C-peptide treatment decreases the inflammatory response and mortality in murine polymicrobial sepsis. Shock (2014) 0.81

Intracellular delivery of HSP70 using HIV-1 Tat protein transduction domain. Biochem Biophys Res Commun (2003) 0.81

The stress response decreases NF-kappaB activation in liver of endotoxemic mice. Shock (2002) 0.81

Heat shock inhibition of lipopolysaccharide-mediated tumor necrosis factor expression is associated with nuclear induction of MKP-1 and inhibition of mitogen-activated protein kinase activation. Crit Care Med (2004) 0.81

Critically associating. Crit Care Med (2009) 0.80

Primary Outcome Measures in Pediatric Septic Shock Trials: A Systematic Review. Pediatr Crit Care Med (2017) 0.80

Short-term modulation of interleukin-1beta signaling by hyperoxia: uncoupling of IkappaB kinase activation and NF-kappaB-dependent gene expression. Am J Physiol Lung Cell Mol Physiol (2003) 0.79

Loss of matrix metalloproteinase-8 is associated with worsened recovery after ischemic kidney injury. Ren Fail (2015) 0.78

Antecedent acute kidney injury worsens subsequent endotoxin-induced lung inflammation in a two-hit mouse model. Am J Physiol Renal Physiol (2011) 0.78

Biological activity of truncated C-terminus human heat shock protein 72. Immunol Lett (2010) 0.78

Therapeutic application of intrapericardial tissue plasminogen activator in a 4-month-old child with complex fibropurulent pericarditis. Pediatr Crit Care Med (2008) 0.77

The immunomodulatory effects of albumin in vitro and in vivo. Adv Pharmacol Sci (2011) 0.77

Finding new therapies for sepsis: the need for patient stratification and the use of genetic biomarkers. Crit Care (2011) 0.77