Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells.

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Published in Nucleic Acids Res on September 29, 2016

Authors

Lisa Rank1, Sebastian Veith1,2, Eva C Gwosch3,4, Janine Demgenski1, Magdalena Ganz3,4, Marjolijn C Jongmans5,6, Christopher Vogel1, Arthur Fischbach1,4, Stefanie Buerger7, Jan M F Fischer1,4, Tabea Zubel1,4, Anna Stier1, Christina Renner1, Michael Schmalz8, Sascha Beneke1,9, Marcus Groettrup7,10, Roland P Kuiper5, Alexander Bürkle1, Elisa Ferrando-May3, Aswin Mangerich11

Author Affiliations

1: Molecular Toxicology Group, Department of Biology, University of Konstanz, D-78457 Konstanz, Germany.
2: Research Training Group 1331, Department of Biology, University of Konstanz, D-78457 Konstanz, Germany.
3: Bioimaging Center, Department of Biology, University of Konstanz, D-78457 Konstanz, Germany.
4: Konstanz Research School Chemical Biology, Department of Biology, University of Konstanz, D-78457 Konstanz, Germany.
5: Department of Human Genetics, Radboud University Medical Center Nijmegen, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.
6: Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherland.
7: FlowKon FACS Facility, Department of Biology, University of Konstanz, D-78457 Konstanz, Germany.
8: Center of Applied Photonics, Department of Physics, Department of Biology, University of Konstanz, D-78457 Konstanz, Germany.
9: Ecotoxicology Group, Department of Biology, University of Konstanz, D-78457 Konstanz, Germany.
10: Immunology Group, Department of Biology, University of Konstanz, D-78457 Konstanz, Germany.
11: Molecular Toxicology Group, Department of Biology, University of Konstanz, D-78457 Konstanz, Germany aswin.mangerich@uni-konstanz.de.

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