Published in Pediatr Crit Care Med on November 01, 2016
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA (2016) 17.49
A randomized trial of protocol-based care for early septic shock. N Engl J Med (2014) 16.05
International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med (2005) 13.40
Goal-directed resuscitation for patients with early septic shock. N Engl J Med (2014) 11.32
Trial of early, goal-directed resuscitation for septic shock. N Engl J Med (2015) 8.24
Sepsis: a roadmap for future research. Lancet Infect Dis (2015) 6.72
Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock. Crit Care Med (2015) 6.64
Trends in the epidemiology of pediatric severe sepsis*. Pediatr Crit Care Med (2013) 2.67
The role of healthcare delivery in the outcome of meningococcal disease in children: case-control study of fatal and non-fatal cases. BMJ (2005) 2.52
Pediatric severe sepsis in U.S. children's hospitals. Pediatr Crit Care Med (2014) 2.43
Pediatric severe sepsis: current trends and outcomes from the Pediatric Health Information Systems database. Pediatr Crit Care Med (2014) 2.41
ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation. Intensive Care Med (2008) 2.40
Developing a clinically feasible personalized medicine approach to pediatric septic shock. Am J Respir Crit Care Med (2015) 2.09
Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and therapies study. Am J Respir Crit Care Med (2015) 2.09
Delayed antimicrobial therapy increases mortality and organ dysfunction duration in pediatric sepsis. Crit Care Med (2014) 1.81
Patient and hospital correlates of clinical outcomes and resource utilization in severe pediatric sepsis. Pediatrics (2007) 1.78
Suboptimal care in the initial management of children who died from severe bacterial infection: a population-based confidential inquiry. Pediatr Crit Care Med (2010) 1.61
Mortality related to invasive infections, sepsis, and septic shock in critically ill children in Australia and New Zealand, 2002-13: a multicentre retrospective cohort study. Lancet Infect Dis (2014) 1.61
Mitochondrial dysfunction in peripheral blood mononuclear cells in pediatric septic shock. Pediatr Crit Care Med (2015) 1.59
A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury. Crit Care Med (2015) 1.49
An emergency department septic shock protocol and care guideline for children initiated at triage. Pediatrics (2011) 1.37
Adherence to PALS Sepsis Guidelines and Hospital Length of Stay. Pediatrics (2012) 1.35
Implementation of goal-directed therapy for children with suspected sepsis in the emergency department. Pediatrics (2011) 1.34
Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock. Am J Respir Crit Care Med (2014) 1.20
Timing of death in children referred for intensive care with severe sepsis: implications for interventional studies. Pediatr Crit Care Med (2015) 1.10
The utility of early lactate testing in undifferentiated pediatric systemic inflammatory response syndrome. Acad Emerg Med (2012) 1.02
Postdischarge mortality in children with acute infectious diseases: derivation of postdischarge mortality prediction models. BMJ Open (2015) 1.02
Improving adherence to PALS septic shock guidelines. Pediatrics (2014) 0.96
Timing of antibiotics, volume, and vasoactive infusions in children with sepsis admitted to intensive care. Crit Care (2015) 0.95
Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study. Crit Care (2015) 0.87
Sepsis and the Global Burden of Disease in Children. JAMA Pediatr (2016) 0.86
Sepsis research and the poorest of the poor. Lancet Infect Dis (2015) 0.85
Association between vasoactive-inotropic score and mortality in pediatric septic shock. Indian Pediatr (2015) 0.82
Resuscitation Bundle in Pediatric Shock Decreases Acute Kidney Injury and Improves Outcomes. J Pediatr (2015) 0.82
Disparities in Adherence to Pediatric Sepsis Guidelines across a Spectrum of Emergency Departments: A Multicenter, Cross-Sectional Observational In Situ Simulation Study. J Emerg Med (2015) 0.81
Neonatal sepsis: an old issue needing new answers. Lancet Infect Dis (2015) 0.78
Extracorporeal therapies in pediatric severe sepsis: findings from the pediatric health-care information system. Crit Care (2015) 0.78
Comparison of Two Sepsis Recognition Methods in a Pediatric Emergency Department. Acad Emerg Med (2015) 0.77
"Beat the Shock Clock": An Interprofessional Team Improves Pediatric Septic Shock Care. Clin Pediatr (Phila) (2015) 0.77
A Survey of the First-Hour Basic Care Tasks of Severe Sepsis and Septic Shock in Pediatric Patients and an Evaluation of Medical Simulation on Improving the Compliance of the Tasks. J Emerg Med (2015) 0.76
Identifying Pediatric Severe Sepsis and Septic Shock: Accuracy of Diagnosis Codes. J Pediatr (2015) 0.76
Lactate Clearance and Normalization and Prolonged Organ Dysfunction in Pediatric Sepsis. J Pediatr (2015) 0.76
Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine. Crit Care Med (2009) 7.55
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents--second edition. Pediatr Crit Care Med (2012) 4.65
Dengue hemorrhagic fever and shock syndromes. Pediatr Crit Care Med (2011) 3.18
Multimodal monitoring for hemodynamic categorization and management of pediatric septic shock: a pilot observational study*. Pediatr Crit Care Med (2014) 2.72
Pediatric severe sepsis in U.S. children's hospitals. Pediatr Crit Care Med (2014) 2.43
Aggressive management of dengue shock syndrome may decrease mortality rate: a suggested protocol. Pediatr Crit Care Med (2005) 2.17
An epidemiologic survey of pediatric sepsis in regional hospitals in China. Pediatr Crit Care Med (2014) 2.16
Developing a clinically feasible personalized medicine approach to pediatric septic shock. Am J Respir Crit Care Med (2015) 2.09
Recommendations for sepsis management in resource-limited settings. Intensive Care Med (2012) 2.03
Post-ICU admission fluid balance and pediatric septic shock outcomes: a risk-stratified analysis. Crit Care Med (2014) 1.72
Dengue and dengue hemorrhagic fever: management issues in an intensive care unit. J Pediatr (Rio J) (2007) 1.66
Care of the child with Ebola virus disease. Pediatr Crit Care Med (2015) 1.62
Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department. Cochrane Database Syst Rev (2009) 1.58
A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury. Crit Care Med (2015) 1.49
Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome. J Pediatr Hematol Oncol (2010) 1.49
A randomized, controlled trial of the impact of early and rapid diagnosis of viral infections in children brought to an emergency department with febrile respiratory tract illnesses. J Pediatr (2008) 1.48
Toward the inclusion of parents on pediatric critical care unit rounds. Pediatr Crit Care Med (2011) 1.46
Dealing with aggressive behavior within the health care team: a leadership challenge. J Crit Care (2006) 1.44
The development of an internet-based knowledge exchange platform for pediatric critical care clinicians worldwide*. Pediatr Crit Care Med (2014) 1.44
Evaluation of a pediatric central venous oximetry catheter in critically ill children. Pediatr Crit Care Med (2010) 1.43
Application of Sepsis Definitions to Pediatric Patients Admitted With Suspected Infections in Uganda. Pediatr Crit Care Med (2016) 1.41
Use of extracorporeal technology during pandemics: ethical and staffing considerations. Pediatr Crit Care Med (2010) 1.38
Computer modeling of patient flow in a pediatric emergency department using discrete event simulation. Pediatr Emerg Care (2007) 1.28
Pediatric post-discharge mortality in resource poor countries: a systematic review. PLoS One (2013) 1.20
Corticosteroids are associated with repression of adaptive immunity gene programs in pediatric septic shock. Am J Respir Crit Care Med (2014) 1.20
Simulation in paediatrics: An educational revolution. Paediatr Child Health (2007) 1.16
Pediatric sepsis in the developing world: challenges in defining sepsis and issues in post-discharge mortality. Clin Epidemiol (2012) 1.13
Association analyses of adrenergic receptor polymorphisms with obesity and metabolic alterations. Metabolism (2007) 1.08
Combining Prognostic and Predictive Enrichment Strategies to Identify Children With Septic Shock Responsive to Corticosteroids. Crit Care Med (2016) 1.08
Discrete event simulation as a tool in optimization of a professional complex adaptive system. Stud Health Technol Inform (2008) 1.06
Bacterial sepsis in Brazilian children: a trend analysis from 1992 to 2006. PLoS One (2011) 1.03
Modeling the metabolic effects of terbutaline in beta2-adrenergic receptor diplotypes. Clin Pharmacol Ther (2004) 1.00
A systematic review: The role and impact of the physician assistant in the emergency department. Emerg Med Australas (2011) 0.98
The burden of sepsis-a call to action in support of World Sepsis Day 2013. J Crit Care (2013) 0.96
Canadians' willingness to receive care from physician assistants. Can Fam Physician (2012) 0.96
Physician-diagnosed asthma and acute chest syndrome: associations with NOS polymorphisms. Pediatr Pulmonol (2007) 0.95
Pediatric Sepsis Biomarker Risk Model-II: Redefining the Pediatric Sepsis Biomarker Risk Model With Septic Shock Phenotype. Crit Care Med (2016) 0.93
Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department. Cochrane Database Syst Rev (2012) 0.92
Clinical research ethics for critically ill patients: a pandemic proposal. Crit Care Med (2010) 0.91
A prospective randomized controlled study of two fluid regimens in the initial management of septic shock in the emergency department. Pediatr Emerg Care (2008) 0.91
Can peripheral blood mononuclear cells be used as a proxy for mitochondrial dysfunction in vital organs during hemorrhagic shock and resuscitation? Shock (2013) 0.89
Introduction and executive summary: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest (2014) 0.89
End-tidal carbon dioxide monitoring in pediatric emergencies. Pediatr Emerg Care (2005) 0.88
Methodology: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest (2014) 0.87
A simulation-based acute care curriculum for pediatric emergency medicine fellowship training programs. Pediatr Emerg Care (2010) 0.87
Intraosseous infusion and pulmonary fat embolism. Pediatr Crit Care Med (2001) 0.87
Effect of montelukast on time-course of exhaled nitric oxide in asthma: influence of LTC4 synthase A(-444)C polymorphism. Pediatr Pulmonol (2003) 0.86
Neonatal and pediatric regionalized systems in pediatric emergency mass critical care. Pediatr Crit Care Med (2011) 0.85
Ultrasound guidance for central vascular access in the pediatric emergency department. Pediatr Emerg Care (2007) 0.85
The impact of an oral rehydration clinical pathway in a paediatric emergency department. Paediatr Child Health (2010) 0.85
Robust coupling of body movement and gaze in young infants. Dev Psychobiol (2007) 0.84
Influence of sex and beta2 adrenergic receptor haplotype on resting and terbutaline-stimulated whole body lipolysis. Metabolism (2005) 0.84
GAP between knowledge and skills for the implementation of the ACCM/PALS septic shock guidelines in India: is the bridge too far? Indian J Crit Care Med (2009) 0.84
Ethical considerations: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest (2014) 0.84
Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department. Cochrane Database Syst Rev (2014) 0.83
Early differentiation between dengue and septic shock by comparison of admission hemodynamic, clinical, and laboratory variables: a pilot study. Pediatr Emerg Care (2007) 0.83
H1N1 pandemic--once more onto the breach, dear friends, once more. Pediatr Crit Care Med (2010) 0.83
Elevated malondialdehyde levels in sepsis - something to 'stress' about? Crit Care (2014) 0.82
Surge capacity principles: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest (2014) 0.81
The role of physician assistants in pediatric emergency medicine: the physician's view. CJEM (2013) 0.81
Triage: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest (2014) 0.81
The role of physician assistants in a pediatric emergency department: a center review and survey. Pediatr Emerg Care (2012) 0.81
Mortality after fluid bolus in African children with sepsis. N Engl J Med (2011) 0.81
American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock. Crit Care Med (2017) 0.81
Exhaled nitric oxide reflects asthma severity and asthma control. Pediatr Crit Care Med (2004) 0.81
Impact of follow-up calls from the pediatric emergency department on return visits within 72 hours: a randomized controlled trial. Pediatr Emerg Care (2014) 0.80
Surge capacity logistics: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest (2014) 0.80
Resuscitation interventions in a tertiary level pediatric emergency department: implications for maintenance of skills. CJEM (2011) 0.80
Bedside echocardiography is useful in assessing children with fluid and inotrope resistant septic shock. Indian J Crit Care Med (2013) 0.80
New or Progressive Multiple Organ Dysfunction Syndrome in Pediatric Severe Sepsis: A Sepsis Phenotype With Higher Morbidity and Mortality. Pediatr Crit Care Med (2017) 0.80
Potential pediatric intensive care unit demand/capacity mismatch due to novel pH1N1 in Canada. Pediatr Crit Care Med (2011) 0.80
Hypothermia therapy for cardiac arrest in pediatric patients. Pediatr Clin North Am (2008) 0.80
Sepsis guideline implementation: benefits, pitfalls and possible solutions. Crit Care (2014) 0.79
A comparison of decision-making by physicians and administrators in healthcare settings. Crit Care (2006) 0.79
Body mass index and the risk of acute injury in adolescents. Paediatr Child Health (2010) 0.79
Culture, communication and safety: lessons from the airline industry. Indian J Pediatr (2010) 0.79
Evacuation of the ICU: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest (2014) 0.79
Pediatric emergency medicine: a world of potential. CJEM (2007) 0.79
Pathophysiology of Pediatric Multiple Organ Dysfunction Syndrome. Pediatr Crit Care Med (2017) 0.78
Vasopressin in pediatric shock and cardiac arrest. Pediatr Crit Care Med (2008) 0.78
Infections of the developing world. Crit Care Clin (2013) 0.78
Engaging pediatric intensive care unit (PICU) clinical staff to lead practice improvement: the PICU participatory action research project (PICU-PAR). Implement Sci (2014) 0.78
Impact of an observation unit and an emergency department-admitted patient transfer mandate in decreasing overcrowding in a pediatric emergency department: a discrete event simulation exercise. Pediatr Emerg Care (2009) 0.78
An international fellowship training program in pediatric emergency medicine: establishing a new subspecialty in the Land of the Dragon. Pediatr Emerg Care (2011) 0.78
Pediatric emergency mass critical care: focus on family-centered care. Pediatr Crit Care Med (2011) 0.77
System-level planning, coordination, and communication: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest (2014) 0.77
Nitric oxide metabolism and the acute chest syndrome of sickle cell anemia. Pediatr Crit Care Med (2008) 0.77
Comparison of Pediatric Severe Sepsis Managed in U.S. and European ICUs. Pediatr Crit Care Med (2016) 0.77
Sepsis and septic shock: progress and future considerations. Indian J Pediatr (2008) 0.77
Monitoring in pediatric cardiac critical care: a worldwide perspective. Pediatr Crit Care Med (2011) 0.77
Preventing intensive care admissions for sepsis in tropical Africa: PICASTA-food for thought. Pediatr Crit Care Med (2013) 0.77
Legal preparedness: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest (2014) 0.77
Engagement and education: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest (2014) 0.77
Emergency management of increased intracranial pressure. Pediatr Emerg Care (2012) 0.77
Effect of continuous blood purification on concentrations of plasma vasoactive substances and cardiac function in endotoxic shock. Pediatr Crit Care Med (2012) 0.76
Amiodarone treatment of junctional ectopic tachycardia in a neonate receiving extracorporeal membrane oxygenation. Ann Pharmacother (2006) 0.76
Recognizing, understanding, and treating critical community acquired methicillin-resistant Staphylococcus aureus infection in children. Pediatr Crit Care Med (2009) 0.76
Family presence during cardiopulmonary resuscitation: our anxiety versus their needs. Pediatr Crit Care Med (2006) 0.76
Supplies and equipment for pediatric emergency mass critical care. Pediatr Crit Care Med (2011) 0.76
Vitamin K deficiency mimicking child abuse. J Emerg Med (2005) 0.76