Published in Nanotechnology on December 14, 2016
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Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I. Nature (2004) 2.39
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Hedgehog regulates smoothened activity by inducing a conformational switch. Nature (2007) 2.23
Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways. Proc Natl Acad Sci U S A (2010) 2.16
A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor. Dev Cell (2006) 2.13
Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy. Mol Cancer Res (2011) 1.76
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Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail. Genes Dev (2003) 1.44
The Caenorhabditis elegans heterochronic regulator LIN-14 is a novel transcription factor that controls the developmental timing of transcription from the insulin/insulin-like growth factor gene ins-33 by direct DNA binding. Mol Cell Biol (2005) 1.44
Oxidation of sulfoxides and arsenic(III) in corrosion of nanoscale zero valent iron by oxygen: evidence against ferryl ions (Fe(IV)) as active intermediates in Fenton reaction. Environ Sci Technol (2010) 1.42
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Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened. PLoS Biol (2011) 1.36
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Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells. J Cell Biol (2011) 1.13
Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors. J Biol Chem (2007) 1.13
A novel mutation in the major intrinsic protein (MIP) associated with autosomal dominant congenital cataracts in a Chinese family. Mol Vis (2010) 1.13
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Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2. Cell Res (2012) 1.11
Dual Roles of Helicobacter pylori NapA in inducing and combating oxidative stress. Infect Immun (2006) 1.11
Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila. PLoS Biol (2012) 1.09
Novel FBN1 mutations associated with predominant ectopia lentis and marfanoid habitus in Chinese patients. Mol Vis (2007) 1.09
Targeted engineering of the Drosophila genome. Fly (Austin) (2009) 1.09
Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus. J Biol Chem (2010) 1.07
Maternal cannabis use alters ventral striatal dopamine D2 gene regulation in the offspring. Biol Psychiatry (2011) 1.07
Actin-related protein 2/3 complex is required for actin ring formation. J Bone Miner Res (2003) 1.07
Decoding the phosphorylation code in Hedgehog signal transduction. Cell Res (2013) 1.06
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Regulation of wingless signaling by the CKI family in Drosophila limb development. Dev Biol (2006) 1.04
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The tomato SlIAA15 is involved in trichome formation and axillary shoot development. New Phytol (2012) 1.02
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Study on differences in the pathology, T cell subsets and gene expression in susceptible and non-susceptible hosts infected with Schistosoma japonicum. PLoS One (2010) 0.98
The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation. Development (2011) 0.98
Emdogain promotes osteoblast proliferation and differentiation and stimulates osteoprotegerin expression. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2004) 0.98
MiR-320a down-regulation mediates bladder carcinoma invasion by targeting ITGB3. Mol Biol Rep (2014) 0.97
Porphyromonas gingivalis lipids inhibit osteoblastic differentiation and function. Infect Immun (2010) 0.97
A nonsense mutation in CRYGC associated with autosomal dominant congenital nuclear cataract in a Chinese family. Mol Vis (2008) 0.96
Intestinal epithelium-derived BMP controls stem cell self-renewal in Drosophila adult midgut. Elife (2014) 0.96
Apoptosis governs the elimination of Schistosoma japonicum from the non-permissive host Microtus fortis. PLoS One (2011) 0.96
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MiR-21 up-regulation mediates glioblastoma cancer stem cells apoptosis and proliferation by targeting FASLG. Mol Biol Rep (2014) 0.94
Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nat Commun (2013) 0.94
Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinases. Mol Cell Biol (2009) 0.94
Using immunoprecipitation to study protein-protein interactions in the Hedgehog-signaling pathway. Methods Mol Biol (2007) 0.94
Modes of failure of ProTaper nickel-titanium rotary instruments after clinical use. J Endod (2007) 0.93
Actin binding activity of subunit B of vacuolar H+-ATPase is involved in its targeting to ruffled membranes of osteoclasts. J Bone Miner Res (2006) 0.93
Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association. PLoS Biol (2013) 0.92
Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila. Proc Natl Acad Sci U S A (2003) 0.92
Lipid peroxidation as a source of oxidative damage in Helicobacter pylori: protective roles of peroxiredoxins. Biochim Biophys Acta (2006) 0.92
Distribution of human papillomavirus 58 and 52 E6/E7 variants in cervical neoplasia in Chinese women. Gynecol Oncol (2010) 0.91
Converse conformational control of smoothened activity by structurally related small molecules. J Biol Chem (2009) 0.90
Cytotoxicity evaluation of Gutta Flow and Endo Sequence BC sealers. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2011) 0.90
Suppression of Hedgehog signaling by Cul3 ligases in proliferation control of retinal precursors. Dev Biol (2007) 0.90
Pd(II)-catalyzed C-H iodination using molecular I2 as the sole oxidant. J Am Chem Soc (2013) 0.89
Dimerization and cytoplasmic localization regulate Hippo kinase signaling activity in organ size control. J Biol Chem (2012) 0.89
Comparison of worm development and host immune responses in natural hosts of Schistosoma japonicum, yellow cattle and water buffalo. BMC Vet Res (2012) 0.89
Nicotinamide adenine dinucleotide (NAD)-regulated DNA methylation alters CCCTC-binding factor (CTCF)/cohesin binding and transcription at the BDNF locus. Proc Natl Acad Sci U S A (2010) 0.89
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Identification of five human novel genes associated with cell proliferation by cell-based screening from an expressed cDNA ORF library. Life Sci (2007) 0.88
Fem1b promotes ubiquitylation and suppresses transcriptional activity of Gli1. Biochem Biophys Res Commun (2013) 0.87
Apical infection spreading to adjacent teeth: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2011) 0.87
MicroRNA expression profile in different tissues of BALB/c mice in the early phase of Schistosoma japonicum infection. Mol Biochem Parasitol (2013) 0.87
Measurement and analysis of light distribution in intralipid-10% at 650 nm. Appl Opt (2003) 0.87