The FACT Complex Promotes Avian Leukosis Virus DNA Integration.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 28122976)

Published in J Virol on March 13, 2017

Authors

Shelby Winans1, Ross C Larue2, Carly M Abraham2, Nikolozi Shkriabai2, Amelie Skopp3, Duane Winkler3, Mamuka Kvaratskhelia2, Karen L Beemon4

Author Affiliations

1: Department of Biology, Johns Hopkins University, Baltimore, Maryland, USA.
2: Center for Retrovirus Research and Comprehensive Cancer Center, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA.
3: Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas, USA.
4: Department of Biology, Johns Hopkins University, Baltimore, Maryland, USA KLB@jhu.edu.

Articles cited by this

HIV-1 integration in the human genome favors active genes and local hotspots. Cell (2002) 12.60

Transcription start regions in the human genome are favored targets for MLV integration. Science (2003) 12.21

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc Natl Acad Sci U S A (1993) 9.17

A quantitative assay for HIV DNA integration in vivo. Nat Med (2001) 8.67

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences. PLoS Biol (2004) 8.27

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients. J Clin Invest (2008) 7.05

HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells. J Biol Chem (2002) 4.91

FACT, a factor that facilitates transcript elongation through nucleosomes. Cell (1998) 4.91

A role for LEDGF/p75 in targeting HIV DNA integration. Nat Med (2005) 4.88

The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins. Nature (1999) 4.69

An essential role for LEDGF/p75 in HIV integration. Science (2006) 4.18

Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency. N Engl J Med (2004) 4.05

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells. J Biol Chem (2003) 3.97

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration. Genes Dev (2007) 3.96

Retroviral DNA integration: viral and cellular determinants of target-site selection. PLoS Pathog (2006) 3.67

Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75. Proc Natl Acad Sci U S A (2005) 3.18

Novel single-cell-level phenotypic assay for residual drug susceptibility and reduced replication capacity of drug-resistant human immunodeficiency virus type 1. J Virol (2004) 3.13

Genome-wide analyses of avian sarcoma virus integration sites. J Virol (2004) 2.68

de FACTo nucleosome dynamics. J Biol Chem (2006) 2.39

Distribution of targets for avian retrovirus DNA integration in vivo. Genes Dev (1994) 1.80

Histone chaperone FACT coordinates nucleosome interaction through multiple synergistic binding events. J Biol Chem (2011) 1.63

Dynamic modulation of HIV-1 integrase structure and function by cellular lens epithelium-derived growth factor (LEDGF) protein. J Biol Chem (2008) 1.61

Integration targeting by avian sarcoma-leukosis virus and human immunodeficiency virus in the chicken genome. J Virol (2005) 1.61

Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors. J Biol Chem (2012) 1.55

The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module. Proc Natl Acad Sci U S A (2008) 1.50

CENP-H-containing complex facilitates centromere deposition of CENP-A in cooperation with FACT and CHD1. Mol Biol Cell (2009) 1.50

The RCAS vector system. Folia Biol (Praha) (2004) 1.48

BET proteins promote efficient murine leukemia virus integration at transcription start sites. Proc Natl Acad Sci U S A (2013) 1.47

Facts about FACT and transcript elongation through chromatin. Curr Opin Genet Dev (2004) 1.40

Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes. Nucleic Acids Res (2013) 1.37

The histone chaperone FACT: structural insights and mechanisms for nucleosome reorganization. J Biol Chem (2011) 1.34

Retroviral integrations in gene therapy trials. Mol Ther (2012) 1.34

Bromo- and extraterminal domain chromatin regulators serve as cofactors for murine leukemia virus integration. J Virol (2013) 1.34

Replication defect of moloney murine leukemia virus with a mutant reverse transcriptase that can incorporate ribonucleotides and deoxyribonucleotides. J Virol (1998) 1.33

The BET family of proteins targets moloney murine leukemia virus integration near transcription start sites. Cell Rep (2013) 1.26

The role of FACT in making and breaking nucleosomes. Biochim Biophys Acta (2011) 1.25

The chicken B cell line DT40: a novel tool for gene disruption experiments. J Immunol Methods (2001) 1.25

Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription. Nucleic Acids Res (2013) 1.12

Retroviral vectors: new applications for an old tool. Gene Ther (2004) 1.10

Host factors for retroviral integration site selection. Trends Biochem Sci (2014) 1.06

HMG domain containing SSRP1 is required for DNA demethylation and genomic imprinting in Arabidopsis. Dev Cell (2011) 1.04

Molecular mechanisms of retroviral integration site selection. Nucleic Acids Res (2014) 1.01

FACT Disrupts Nucleosome Structure by Binding H2A-H2B with Conserved Peptide Motifs. Mol Cell (2015) 1.00

Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction. Nucleic Acids Res (2014) 1.00

The histone chaperone facilitates chromatin transcription (FACT) protein maintains normal replication fork rates. J Biol Chem (2011) 0.99

Stepwise analysis of reverse transcription in a cell-to-cell human immunodeficiency virus infection model: kinetics and implications. J Gen Virol (1995) 0.99

Structure of the Spt16 middle domain reveals functional features of the histone chaperone FACT. J Biol Chem (2013) 0.98

A role for SSRP1 in recombination-mediated DNA damage response. J Cell Biochem (2009) 0.95

Reference gene selection for normalization of PCR analysis in chicken embryo fibroblast infected with H5N1 AIV. Virol Sin (2010) 0.95

Histone chaperone FACT regulates homologous recombination by chromatin remodeling through interaction with RNF20. J Cell Sci (2013) 0.93

BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements. Mol Ther Nucleic Acids (2014) 0.91

Complex mutual regulation of facilitates chromatin transcription (FACT) subunits on both mRNA and protein levels in human cells. Cell Cycle (2013) 0.87

Large-scale preparation and concentration of retrovirus stocks. Curr Protoc Mol Biol (2001) 0.85

Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes. Nucleic Acids Res (2014) 0.84

Host Factors in Retroviral Integration and the Selection of Integration Target Sites. Microbiol Spectr (2014) 0.83

Structure of the Brd4 ET domain bound to a C-terminal motif from γ-retroviral integrases reveals a conserved mechanism of interaction. Proc Natl Acad Sci U S A (2016) 0.82

Marek's disease virus induces Th-2 activity during cytolytic infection. Viral Immunol (2008) 0.82

Analysis of 2-LTR circle junctions of viral DNA in infected cells. Methods Mol Biol (2009) 0.80

In Vivo Mapping of FACT-Histone Interactions Identifies a Role of Pob3 C-terminus in H2A-H2B Binding. ACS Chem Biol (2015) 0.79

Crystal Structure of Human SSRP1 Middle Domain Reveals a Role in DNA Binding. Sci Rep (2015) 0.77

B'-protein phosphatase 2A is a functional binding partner of delta-retroviral integrase. Nucleic Acids Res (2015) 0.76