Published in Cell Signal on February 09, 2017
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics (1989) 105.30
New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene (1988) 42.65
Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics (1996) 24.62
Cyclin is degraded by the ubiquitin pathway. Nature (1991) 17.93
Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol (1983) 12.99
The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol (2006) 10.76
Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev (1996) 8.28
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science (1997) 8.00
Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1. Nature (1999) 7.21
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J Cell Biol (2001) 6.80
The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes Dev (2000) 6.43
The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes Dev (1998) 5.96
An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast. Cell (1998) 5.29
Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1. Mol Cell (1998) 5.28
Segregating sister genomes: the molecular biology of chromosome separation. Science (2002) 4.92
Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth. Nature (2000) 4.52
The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction. Nat Cell Biol (2008) 4.08
APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5. Nature (1999) 4.05
Mitotic regulation of the APC activator proteins CDC20 and CDH1. Mol Biol Cell (2000) 4.01
Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex. Mol Biol Cell (2002) 3.65
Guide to yeast genetics and molecular biology. Methods Enzymol (1991) 3.61
MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity. Proc Natl Acad Sci U S A (1997) 3.42
Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins. Science (1998) 3.38
MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol (2000) 3.31
The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates. Mol Cell (2005) 2.77
Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters. Nature (2000) 2.74
TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. Curr Biol (2003) 2.71
Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover. Nat Rev Mol Cell Biol (2003) 2.64
Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC. EMBO J (2001) 2.55
Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle. Genes Dev (2002) 2.52
The regulation of Cdc20 proteolysis reveals a role for APC components Cdc23 and Cdc27 during S phase and early mitosis. Curr Biol (1998) 2.43
Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint. Genes Dev (2007) 2.32
Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae. Genes Dev (2004) 2.11
Exit from mitosis in budding yeast: biphasic inactivation of the Cdc28-Clb2 mitotic kinase and the role of Cdc20. Mol Cell (2000) 2.10
Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1. J Biol Chem (1997) 2.07
A role for the Fizzy/Cdc20 family of proteins in activation of the APC/C distinct from substrate recruitment. Mol Cell (2008) 1.95
Securin and B-cyclin/CDK are the only essential targets of the APC. Nat Cell Biol (2003) 1.84
NDD1, a high-dosage suppressor of cdc28-1N, is essential for expression of a subset of late-S-phase-specific genes in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.75
A competitive transcription factor binding mechanism determines the timing of late cell cycle-dependent gene expression. Mol Cell (2010) 1.74
The protein kinase Kin4 inhibits exit from mitosis in response to spindle position defects. Mol Cell (2005) 1.67
The APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation. Mol Cell (2012) 1.47
Regulation of cell cycle-specific gene expression through cyclin-dependent kinase-mediated phosphorylation of the forkhead transcription factor Fkh2p. Mol Cell Biol (2004) 1.46
Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Nature (2003) 1.42
Two different modes of cyclin clb2 proteolysis during mitosis in Saccharomyces cerevisiae. FEBS Lett (2000) 1.25
The CRY box: a second APCcdh1-dependent degron in mammalian cdc20. EMBO Rep (2006) 1.21
Ubiquitination of Cdc20 by the APC occurs through an intramolecular mechanism. Curr Biol (2011) 1.10
Regulation of a transcription factor network by Cdk1 coordinates late cell cycle gene expression. EMBO J (2014) 0.92
Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint. EMBO Rep (2014) 0.87