Published in Proc Natl Acad Sci U S A on August 01, 1988
Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc Natl Acad Sci U S A (1994) 2.30
Cancer stem cells from colorectal cancer-derived cell lines. Proc Natl Acad Sci U S A (2010) 2.22
Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro. Am J Pathol (2003) 1.80
Identification of a talin binding site in the cytoskeletal protein vinculin. J Cell Biol (1989) 1.60
Human colon carcinoma cells use multiple receptors to adhere to laminin: involvement of alpha 6 beta 4 and alpha 2 beta 1 integrins. Cell Regul (1990) 1.55
Deregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiation. Neoplasia (2002) 1.37
Morphoregulatory activities of E-cadherin and beta-1 integrins in colorectal tumour cells. Br J Cancer (1992) 1.28
Low expression of collagen receptors in moderate and poorly differentiated colorectal adenocarcinomas. Br J Cancer (1990) 1.25
Carcinoembryonic antigen functions as an accessory adhesion molecule mediating colon epithelial cell-collagen interactions. Proc Natl Acad Sci U S A (1990) 1.23
Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells. Proc Natl Acad Sci U S A (1999) 1.23
Mapping the heparin-binding sites on type I collagen monomers and fibrils. J Cell Biol (1994) 1.08
Molecular genetics of colorectal carcinoma. BMJ (1989) 0.82
Reversal of glandular polarity in the lymphovascular compartment of breast cancer. J Clin Pathol (2004) 0.81
Are different events involved in the development of sporadic versus hereditary tumours? The possible importance of the microenvironment in hereditary cancer. Br J Cancer (1990) 0.80
The second Bagshawe lecture. Matching basic research to the management of cancer: the view from the other side of the fence. Br J Cancer (1990) 0.78
Establishment and characterisation of two cell lines derived from a primary adenocarcinoma of the duodenum. Clin Mol Pathol (1996) 0.75
New perspectives in cell adhesion: RGD and integrins. Science (1987) 18.41
Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature (1977) 16.54
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell (1978) 14.82
Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature (1984) 14.25
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature (1983) 11.57
The spread of rectal cancer and its effect on prognosis. Br J Cancer (1958) 10.06
The growth of cells on a transparent gel of reconstituted rat-tail collagen. J Natl Cancer Inst (1956) 7.73
Classification of human colorectal adenocarcinoma cell lines. Cancer Res (1976) 7.00
How does the extracellular matrix direct gene expression? J Theor Biol (1982) 6.38
The 24 fluorescence patterns of the human metaphase chromosomes - distinguishing characters and variability. Hereditas (1972) 6.31
Production of mammalian somatic cell hybrids by means of polyethylene glycol treatment. Somatic Cell Genet (1975) 4.74
Chromosome 5 allele loss in human colorectal carcinomas. Nature (1987) 4.46
The use of proteolytic enzymes for the mapping of structural rearrangements in the chromosomes of man. Chromosoma (1972) 3.63
Characterization of a monoclonal anti-beta 2-microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens. Eur J Immunol (1979) 3.27
A monoclonal antibody to the human epidermal growth factor receptor. J Cell Biochem (1982) 3.04
Human colonic adenocarcinoma cells. I. Establishment and description of a new line. In Vitro (1976) 2.65
Lumen formation by epithelial cell lines in response to collagen overlay: a morphogenetic model in culture. Proc Natl Acad Sci U S A (1982) 2.44
Regulation of pigment synthesis in mammalian cells, as studied by somatic hybridization. Proc Natl Acad Sci U S A (1966) 2.36
Differential staining of human and mouse chromosomes in interspecific cell hybrids. Nature (1974) 2.28
Genetics of human cancer. Annu Rev Genet (1986) 2.28
Detachment of cells from culture substrate by soluble fibronectin peptides. J Cell Biol (1985) 2.26
Sustained growth and three-dimensional organization of primary mammary tumor epithelial cells embedded in collagen gels. Proc Natl Acad Sci U S A (1979) 2.15
A cell surface receptor complex for collagen type I recognizes the Arg-Gly-Asp sequence. J Cell Biol (1987) 2.04
A human X-linked antigen defined by a monoclonal antibody. Somatic Cell Genet (1980) 1.64
A monoclonal antibody recognizing a cell surface antigen coded for by a gene on human chromosome 17. Ann Hum Genet (1982) 1.46
Characterization and chromosomal assignment of a human cell surface antigen defined by the monoclonal antibody AUAI. Int J Cancer (1986) 1.45
Recent advances in research on fibronectin and other cell attachment proteins. J Cell Biochem (1985) 1.38
Different mechanisms in the attachment of cells to native and denatured collagen. J Cell Sci (1979) 1.37
Expression of human transferrin receptor is controlled by a gene on chromosome 3: assignment using species specificity of a monoclonal antibody. Somatic Cell Genet (1982) 1.23
A human cell-surface antigen defined by a monoclonal antibody and controlled by a gene on human chromosome 1. Ann Hum Genet (1985) 1.18
A cell line from an induced carcinoma of mouse rectum. J Pathol (1978) 1.16
Colonic pericrypt sheath cells: characterisation of cell type with new monoclonal antibody. J Clin Pathol (1987) 1.11
A human cell-surface antigen defined by a monoclonal antibody and controlled by a gene on chromosome 12. Somatic Cell Genet (1981) 1.04
Assignment of a fibronection gene to human chromosome 2 using monoclonal antibodies. Exp Cell Res (1982) 1.02
Comparative analysis of the sequences of the three collagen chains alpha 1(I), alpha 2 and alpha 1(III) Functional and genetic aspects. J Mol Biol (1980) 0.91
Monoclonal antibodies that distinguish between human cellular and plasma fibronectin. Mol Biol Med (1984) 0.91
Human muscle cell surface antigen 16.3A5 is encoded by a gene on chromosome 11. Somat Cell Mol Genet (1984) 0.87
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell (1978) 14.82
Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature (1987) 10.21
The number of balanced polymorphisms that can be maintained in a natural population. Genetics (1967) 8.80
Linkage and selection: theoretical analysis of the deterministic two locus random mating model. Genetics (1967) 7.12
Monoclonal antibodies for analysis of the HLA system. Immunol Rev (1979) 6.63
HL-A, immune-response genes, and disease. Lancet (1974) 5.67
p53 mutations in colorectal cancer. Proc Natl Acad Sci U S A (1990) 5.43
Use of a monoclonal antibody (W6/32) in structural studies of HLA-A,B,C, antigens. J Immunol (1979) 5.06
A migration matrix model for the study of random genetic drift. Genetics (1968) 4.59
Chromosome 5 allele loss in human colorectal carcinomas. Nature (1987) 4.46
HL-A antigens and disease. Statistical and genetical considerations. Tissue Antigens (1974) 4.41
Monoclonal antibody to cytokeratin for use in routine histopathology. J Clin Pathol (1984) 4.36
Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proc Natl Acad Sci U S A (1999) 4.35
The ABC of APC. Hum Mol Genet (2001) 4.16
Evolutionary significance of the HL-A system. Nature (1972) 4.06
Monoclonal antibodies to epithelium-specific components of the human milk fat globule membrane: production and reaction with cells in culture. Int J Cancer (1981) 3.90
Beta-catenin mutations in cell lines established from human colorectal cancers. Proc Natl Acad Sci U S A (1997) 3.79
Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas. Lancet (1992) 3.44
APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits". Proc Natl Acad Sci U S A (2000) 3.41
The Eurasian heartland: a continental perspective on Y-chromosome diversity. Proc Natl Acad Sci U S A (2001) 3.38
Characterization of a monoclonal anti-beta 2-microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens. Eur J Immunol (1979) 3.27
Nomenclature for factors of the HLA system, 2010. Tissue Antigens (2010) 3.22
Recombination and integration in Bacillus subtilis transformation: involvement of DNA synthesis. J Mol Biol (1965) 3.21
Evolution of sickle variant gene. Lancet (1979) 3.09
Monoclonal antibody to a human histocompatibility alloantigen, HLA-A2. Nature (1978) 2.93
Evolution and function of the HLA system. Br Med Bull (1978) 2.91
The mutation rate and cancer. Proc Natl Acad Sci U S A (1996) 2.73
Histocompatibility (HL-A) antigens associated with systemic lupus erythematosus. A possible genetic predisposition to disease. N Engl J Med (1971) 2.69
CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli. Proc Natl Acad Sci U S A (1989) 2.66
Protein clinical manifestations of primary tumors of the heart. Am J Med (1972) 2.61
Human genetics: the molecular challenge. Cold Spring Harb Symp Quant Biol (1986) 2.54
cDNA clones coding for the heavy chain of human HLA-DR antigen. Proc Natl Acad Sci U S A (1982) 2.51
Targeting of iodine-123-labelled tumour-associated monoclonal antibodies to ovarian, breast, and gastrointestinal tumours. Lancet (1982) 2.51
The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin. Tissue Antigens (1978) 2.40
Integration of deoxyribonuclease-treated DNA in bacillus subtilis transformation. J Gen Physiol (1966) 2.32
The beta2-microglobulin gene is on chromosome 15 and not in the HL-A region. Nature (1975) 2.29
The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history. Proc Natl Acad Sci U S A (1998) 2.27
Polyclonal origin of colonic adenomas in an XO/XY patient with FAP. Science (1996) 2.22
Sequence of an HLA-DR alpha-chain cDNA clone and intron-exon organization of the corresponding gene. Nature (1982) 2.18
Cellular distrubtion, purification, and molecular nature of human Ia antigens. Scand J Immunol (1977) 2.04
Chromosomal localisation of the human homologues to the oncogenes erbA and B. EMBO J (1984) 2.02
A monoclonal antibody that detects HLA-D region antigen in routinely fixed, wax embedded sections of normal and neoplastic lymphoid tissues. J Clin Pathol (1985) 2.00
Assignment of the structural gene for the third component of human complement to chromosome 19. Proc Natl Acad Sci U S A (1982) 2.00
Rapid isolation of human chromosome-specific DNA probes from a somatic cell hybrid. Genomics (1990) 1.99
Genetic factors in Hodgkin's disease: association with a disease-susceptibility locus (DSA) in the HL-A region. Natl Cancer Inst Monogr (1973) 1.98
Nomenclature for factors of the HLA system, 1990. Tissue Antigens (1991) 1.98
Clinical and molecular features of the hereditary mixed polyposis syndrome. Gastroenterology (1997) 1.96
Chromosomal localization of human cellular homologues of two viral oncogenes. Nature (1982) 1.96
Six HLA-D region alpha-chain genes on human chromosome 6: polymorphisms and associations of DC alpha-related sequences with DR types. Proc Natl Acad Sci U S A (1984) 1.90
Nomenclature for factors of the HLA system, 2002. Tissue Antigens (2002) 1.89
Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement. Proc Natl Acad Sci U S A (2001) 1.85
Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens. Immunology (1983) 1.85
Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin. Proc Natl Acad Sci U S A (2000) 1.83
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. Am J Hum Genet (2001) 1.81
New genetic model for allelism at histocompatibility and other complex loci: polymorphism for control of gene expression. Transplant Proc (1973) 1.80
Failure of programmed cell death and differentiation as causes of tumors: some simple mathematical models. Proc Natl Acad Sci U S A (1995) 1.78
Use of two epithelium-specific monoclonal antibodies for diagnosis of malignancy in serous effusions. Lancet (1982) 1.76
APC in the regulation of intestinal crypt fission. J Pathol (1998) 1.73
Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. Proc Natl Acad Sci U S A (1998) 1.70
Genetic testing is important in families with a history suggestive of hereditary non-polyposis colorectal cancer even if the Amsterdam criteria are not fulfilled. Br J Surg (1997) 1.66
SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway. Proc Natl Acad Sci U S A (2001) 1.65
Molecular structure of human histocompatibility antigens: the HLA-C series. Eur J Immunol (1977) 1.61
Two-dimensional gel analysis of the polypeptides precipitated by a polymorphic HLA-DR1,2,w6 monoclonal antibody: evidence for a third locus. Eur J Immunol (1982) 1.59
Nomenclature for factors of the HLA system, 1991. WHO Nomenclature Committee for factors of the HLA system. Tissue Antigens (1992) 1.58
Nomenclature for factors of the HLA system, 2004. Tissue Antigens (2005) 1.57
Expression of HLA antigens, beta 2-microglobulin and enzymes by human amniotic epithelial cells. Nature (1982) 1.57
Expression of HLA system antigens on placenta. Transplantation (1976) 1.56
Intron splice acceptor site sequence variation in the hereditary non-polyposis colorectal cancer gene hMSH2. Eur J Cancer (1994) 1.54
HLA polymorphism in Israel. 9. An overall comparative analysis. Tissue Antigens (1978) 1.54
Genetic pathways in colorectal and other cancers. Eur J Cancer (1999) 1.53
Monoclonal antibodies to HLA--DRw determinants. Tissue Antigens (1980) 1.49
Genetic pathways in colorectal and other cancers. Eur J Cancer (1999) 1.49
Permanent lymphoid lines from genetically marked lymphocytes: success with lymphocytes recovered from frozen storage. Tissue Antigens (1976) 1.48
Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome. Cancer Res (1997) 1.47
Chromosome assignment of some human enzyme loci: mitochondrial malate dehydrogenase to 7, mannosephosphate isomerase and pyruvate kinase to 15 and probably, esterase D to 13. Ann Hum Genet (1975) 1.45
Characterization and chromosomal assignment of a human cell surface antigen defined by the monoclonal antibody AUAI. Int J Cancer (1986) 1.45
A rapid micro method for counting cells "in situ" using a fluorogenic alkaline phosphatase enzyme assay. In Vitro Cell Dev Biol (1989) 1.45
Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1. Proc Natl Acad Sci U S A (1999) 1.45
Human gene mapping using an X/autosome translocation. Somatic Cell Genet (1976) 1.44
A family study of the association between insulin dependent diabetes mellitus, autoantibodies and the HLA system. Tissue Antigens (1984) 1.44
Genetics and serology of HL-A-linked human Ia antigens. Cold Spring Harb Symp Quant Biol (1977) 1.42
HLA-DP based resistance to Hodgkin's disease. Lancet (1989) 1.42
Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours. Hum Mutat (1998) 1.41
Nomenclature for factors of the HLA system, 1998. Tissue Antigens (1999) 1.40
Phenotypic expression in familial adenomatous polyposis: partial prediction by mutation analysis. Gut (1994) 1.39
Medical genetics in China. J Med Genet (1979) 1.39
A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin. Eur J Immunol (1982) 1.39
Subcellular separation and molecular nature of human histocompatibility antigens (HL-A). Nature (1974) 1.39
Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC. Proc Natl Acad Sci U S A (2002) 1.36
Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines. Proc Natl Acad Sci U S A (1993) 1.34
Nomenclature for factors of the HLA system, 1995. Tissue Antigens (1995) 1.34
CDX1 is an important molecular mediator of Barrett's metaplasia. Proc Natl Acad Sci U S A (2005) 1.34
DNA mismatch repair genes and colorectal cancer. Gut (2000) 1.34
Analysis of genetic and phenotypic heterogeneity in juvenile polyposis. Gut (2000) 1.34
Demonstration of two distinct light chains in HLA-DR-associated antigens by two-dimensional gel electrophoresis. Eur J Immunol (1982) 1.33
Serum marker potential of placental alkaline phosphatase-like activity in testicular germ cell tumours evaluated by H17E2 monoclonal antibody assay. Br J Cancer (1985) 1.32
Expression of low molecular weight cytokeratin proteins in cervical neoplasia. J Pathol (1986) 1.31
Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer. Gut (2001) 1.29
Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice. Proc Natl Acad Sci U S A (1997) 1.29
Beta 2-microglobulin gene mutations: a study of established colorectal cell lines and fresh tumors. Proc Natl Acad Sci U S A (1994) 1.29