Published in Nat Struct Mol Biol on June 06, 2017
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RTEL1 maintains genomic stability by suppressing homologous recombination. Cell (2008) 3.84
Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science (2009) 3.68
Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins. Nature (2008) 3.67
A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination. Mol Cell (2007) 3.23
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Mol Cell (2013) 3.05
Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia. Mol Cell (2010) 2.91
Inhibition of homologous recombination by the PCNA-interacting protein PARI. Mol Cell (2011) 2.61
A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites. EMBO J (2006) 2.41
MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism. Science (2012) 2.39
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity. Cell (2012) 2.24
FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex. Mol Cell (2008) 2.14
Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis. Curr Biol (2002) 2.06
NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies. Mol Cell (2013) 1.97
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FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. J Biol Chem (2008) 1.93
Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair. Mol Cell (2010) 1.90
HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability. Nat Cell Biol (2007) 1.77
HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis. Dev Cell (2008) 1.76
RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair. Mol Cell Biol (2005) 1.74
RTEL-1 enforces meiotic crossover interference and homeostasis. Science (2010) 1.70
Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast. Genes Dev (2008) 1.68
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HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature (2013) 1.57
BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair. J Cell Sci (2012) 1.55
DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair. Mol Cell Biol (2007) 1.53
Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates. PLoS Genet (2009) 1.52
CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability. Mol Cell (2010) 1.51
The choice in meiosis - defining the factors that influence crossover or non-crossover formation. J Cell Sci (2011) 1.49
Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells. Cancer Res (2007) 1.48
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Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways. DNA Repair (Amst) (2008) 1.33
Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2. Proc Natl Acad Sci U S A (2007) 1.30
Replication blocking lesions present a unique substrate for homologous recombination. EMBO J (2007) 1.29
The centriolar satellite protein Cep131 is important for genome stability. J Cell Sci (2012) 1.27
RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination. Nucleic Acids Res (2010) 1.27
RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication. Science (2013) 1.21
C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repair. DNA Repair (Amst) (2006) 1.14
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Emerging links between the biological clock and the DNA damage response. Chromosoma (2007) 1.12
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Meiotic recombination in Caenorhabditis elegans. Chromosome Res (2007) 1.08
Joint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosis. PLoS Genet (2013) 1.06
A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome. PLoS Genet (2013) 1.05
Phosphorylation of the cyclin-dependent kinase inhibitor p21Cip1 on serine 130 is essential for viral cyclin-mediated bypass of a p21Cip1-imposed G1 arrest. Mol Cell Biol (2006) 1.05
Abrogation of the CLK-2 checkpoint leads to tolerance to base-excision repair intermediates. EMBO Rep (2006) 0.98
BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair. EMBO Rep (2008) 0.97
The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans. EMBO J (2009) 0.93
C. elegans: a model of Fanconi anemia and ICL repair. Mutat Res (2008) 0.92
Alternative induction of meiotic recombination from single-base lesions of DNA deaminases. Genetics (2009) 0.89
Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein. J Biol Chem (2013) 0.89
BRCA1 ubiquitylation of CtIP: Just the tIP of the iceberg? DNA Repair (Amst) (2006) 0.89
The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling. Cell Cycle (2014) 0.88
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with multifunctional angiogenin to utilize its antiapoptotic functions. J Virol (2012) 0.85
Metabolism of postsynaptic recombination intermediates. FEBS Lett (2010) 0.82
High-throughput expression, purification, and characterization of recombinant Caenorhabditis elegans proteins. Biochem Biophys Res Commun (2003) 0.81
FANCM-FAAP24 and HCLK2: roles in ATR signalling and the Fanconi anemia pathway. Cell Cycle (2009) 0.78
Helicase and translocases required for the maintenance of genome stability. DNA Repair (Amst) (2010) 0.77
FANCM: fork pause, rewind and play. EMBO J (2010) 0.77
DNA repair: Decision at the break point. Nature (2010) 0.77
Differential regulation of the PIKK kinase family by Tel2. Cell Cycle (2008) 0.76
DNA repair: A heavyweight joins the fray. Nature (2009) 0.76
How to exchange your partner. Workshop on recombination mechanisms and the maintenance of genomic stability. EMBO Rep (2006) 0.75
TRF2 Recruits RTEL1 to Telomeres in S Phase to Promote T-Loop Unwinding. Mol Cell (2016) 0.75
RTEL1 Inhibits Trinucleotide Repeat Expansions and Fragility. Cell Rep (2016) 0.75