Published in Science on March 05, 2010
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The Arabidopsis thaliana homolog of the helicase RTEL1 plays multiple roles in preserving genome stability. Plant Cell (2014) 0.80
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RTEL1 polymorphisms are associated with lung cancer risk in the Chinese Han population. Oncotarget (2016) 0.75
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Early decision; meiotic crossover interference prior to stable strand exchange and synapsis. Cell (2004) 3.47
Condensins regulate meiotic DNA break distribution, thus crossover frequency, by controlling chromosome structure. Cell (2009) 3.07
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ZHP-3 acts at crossovers to couple meiotic recombination with synaptonemal complex disassembly and bivalent formation in C. elegans. PLoS Genet (2008) 1.64
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RTEL1 maintains genomic stability by suppressing homologous recombination. Cell (2008) 3.84
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Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2. Nat Struct Mol Biol (2007) 3.45
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. Cell (2010) 3.43
Identification of Holliday junction resolvases from humans and yeast. Nature (2008) 3.33
Structural and functional relationships of the XPF/MUS81 family of proteins. Annu Rev Biochem (2008) 3.32
A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination. Mol Cell (2007) 3.23
Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination. Mol Cell (2005) 3.16
C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis. Genes Dev (2002) 3.13
Condensins regulate meiotic DNA break distribution, thus crossover frequency, by controlling chromosome structure. Cell (2009) 3.07
RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Mol Cell (2013) 3.05
RAD51C is required for Holliday junction processing in mammalian cells. Science (2004) 3.05
Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia. Mol Cell (2010) 2.91
The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates. Nature (2006) 2.86
Inhibition of homologous recombination by the PCNA-interacting protein PARI. Mol Cell (2011) 2.61
Defective DNA repair and neurodegenerative disease. Cell (2007) 2.57
Condensin and cohesin: more than chromosome compactor and glue. Nat Rev Genet (2003) 2.56
TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation. Curr Biol (2002) 2.51
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FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia. Mol Cell (2009) 2.29
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity. Cell (2012) 2.24
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Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair. Mol Cell (2010) 1.90
Chromosome cohesion is regulated by a clock gene paralogue TIM-1. Nature (2003) 1.90
Telomere maintenance requires the RAD51D recombination/repair protein. Cell (2004) 1.89
Clustered DNA motifs mark X chromosomes for repression by a dosage compensation complex. Nature (2006) 1.88
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Condensin restructures chromosomes in preparation for meiotic divisions. J Cell Biol (2004) 1.85
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HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis. Dev Cell (2008) 1.76
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Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. EMBO J (2003) 1.68
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Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells. Mol Cell (2013) 1.67
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The axial element protein HTP-3 promotes cohesin loading and meiotic axis assembly in C. elegans to implement the meiotic program of chromosome segregation. Genes Dev (2009) 1.62
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BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair. J Cell Sci (2012) 1.55
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DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair. Mol Cell Biol (2007) 1.53