Published in Lab Chip on July 20, 2017
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
PatternHunter: faster and more sensitive homology search. Bioinformatics (2002) 35.65
ZOOM! Zillions of oligos mapped. Bioinformatics (2008) 29.78
Mouse genomic variation and its effect on phenotypes and gene regulation. Nature (2011) 10.66
Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol (2002) 10.15
Epidermal electronics. Science (2011) 8.65
Stretching single talin rod molecules activates vinculin binding. Science (2009) 8.11
The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev Cell (2003) 6.86
DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer. N Engl J Med (2015) 5.39
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell (2006) 5.36
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol (2009) 5.27
PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. J Exp Med (2010) 4.74
PEAKS: powerful software for peptide de novo sequencing by tandem mass spectrometry. Rapid Commun Mass Spectrom (2003) 4.56
An immunosurveillance mechanism controls cancer cell ploidy. Science (2012) 4.35
Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells. Nat Struct Mol Biol (2013) 4.04
CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat Med (2002) 4.02
Human infection with avian influenza A H7N9 virus: an assessment of clinical severity. Lancet (2013) 3.90
APOBEC3 proteins mediate the clearance of foreign DNA from human cells. Nat Struct Mol Biol (2010) 3.61
Paternally inherited inactivating mutations of the GNAS1 gene in progressive osseous heteroplasia. N Engl J Med (2002) 3.31
Biological features of novel avian influenza A (H7N9) virus. Nature (2013) 3.24
Mental health system in China: history, recent service reform and future challenges. World Psychiatry (2011) 3.23
The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture. Proc Natl Acad Sci U S A (2006) 3.19
The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin. J Biol Chem (2003) 2.89
DNACompress: fast and effective DNA sequence compression. Bioinformatics (2002) 2.82
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection. Nature (2011) 2.71
Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles. J Am Chem Soc (2004) 2.54
C. elegans screen identifies autophagy genes specific to multicellular organisms. Cell (2010) 2.50
Obesity and incidence of lung cancer: a meta-analysis. Int J Cancer (2012) 2.48
A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates. PLoS One (2007) 2.47
Th17 and natural Treg cell population dynamics in systemic lupus erythematosus. Arthritis Rheum (2009) 2.43
Discovering patterns to extract protein-protein interactions from full texts. Bioinformatics (2004) 2.42
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements. Am J Hum Genet (2013) 2.40
Molecular censusing doubles giant panda population estimate in a key nature reserve. Curr Biol (2006) 2.39
NONCODEv4: exploring the world of long non-coding RNA genes. Nucleic Acids Res (2013) 2.37
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. J Clin Invest (2013) 2.30
RAPTOR: optimal protein threading by linear programming. J Bioinform Comput Biol (2003) 2.27
Regulation of p53 target gene expression by peptidylarginine deiminase 4. Mol Cell Biol (2008) 2.27
Human thymic stromal lymphopoietin promotes dendritic cell-mediated CD4+ T cell homeostatic expansion. Nat Immunol (2004) 2.27
Waterproof AlInGaP optoelectronics on stretchable substrates with applications in biomedicine and robotics. Nat Mater (2010) 2.20
Foxa2 and H2A.Z mediate nucleosome depletion during embryonic stem cell differentiation. Cell (2012) 2.02
"Nerve combing" for trigeminal neuralgia without vascular compression: report of 10 cases. Clin J Pain (2009) 2.01
From dopamine to salience to psychosis--linking biology, pharmacology and phenomenology of psychosis. Schizophr Res (2005) 2.00
Selection of appropriate reference genes for gene expression studies by quantitative real-time polymerase chain reaction in cucumber. Anal Biochem (2009) 1.96
Global impact of oncogenic Src on a phosphotyrosine proteome. J Proteome Res (2008) 1.94
Role of C. elegans TAT-1 protein in maintaining plasma membrane phosphatidylserine asymmetry. Science (2008) 1.93
Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1. Proc Natl Acad Sci U S A (2012) 1.91
Human IgG2 antibodies display disulfide-mediated structural isoforms. J Biol Chem (2008) 1.88
What do we need to know about speciation? Trends Ecol Evol (2011) 1.82
Pro12Ala polymorphism in the PPARG gene contributes to the development of diabetic nephropathy in Chinese type 2 diabetic patients. Diabetes Care (2009) 1.82
Increasing fluoroquinolone resistance in Campylobacter jejuni, Pennsylvania, USA,1982-2001. Emerg Infect Dis (2002) 1.81
L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice. J Lipid Res (2008) 1.80
FePt@CoS(2) yolk-shell nanocrystals as a potent agent to kill HeLa cells. J Am Chem Soc (2007) 1.80
1B50-1, a mAb raised against recurrent tumor cells, targets liver tumor-initiating cells by binding to the calcium channel α2δ1 subunit. Cancer Cell (2013) 1.79
Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. Nat Genet (2012) 1.78
A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy. Nat Genet (2011) 1.77
Dynamically tunable hemispherical electronic eye camera system with adjustable zoom capability. Proc Natl Acad Sci U S A (2011) 1.74
Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity. Proc Natl Acad Sci U S A (2005) 1.73
CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21. J Clin Invest (2011) 1.71
Extracorporeal high intensity focused ultrasound ablation in the treatment of 1038 patients with solid carcinomas in China: an overview. Ultrason Sonochem (2004) 1.70
The hOGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis. Breast Cancer Res Treat (2010) 1.69
Bisphenol A levels in blood and urine in a Chinese population and the personal factors affecting the levels. Environ Res (2009) 1.67
Cav3.1 (alpha1G) T-type Ca2+ channels mediate vaso-occlusion of sickled erythrocytes in lung microcirculation. Circ Res (2003) 1.66
Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway. J Bacteriol (2006) 1.66
Equivalence of protein inventories obtained from formalin-fixed paraffin-embedded and frozen tissue in multidimensional liquid chromatography-tandem mass spectrometry shotgun proteomic analysis. Mol Cell Proteomics (2009) 1.66
Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα. J Clin Invest (2014) 1.66
Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces. Structure (2010) 1.65
RN181 suppresses hepatocellular carcinoma growth by inhibition of the ERK/MAPK pathway. Hepatology (2011) 1.64
Surgery for patients with Marfan syndrome with type A dissection involving the aortic arch using total arch replacement combined with stented elephant trunk implantation: the acute versus the chronic. J Thorac Cardiovasc Surg (2011) 1.62
Genetic viability and population history of the giant panda, putting an end to the "evolutionary dead end"? Mol Biol Evol (2007) 1.61
Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats. Hypertension (2009) 1.61
In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis. Cancer Res (2005) 1.61
Acupuncture mobilizes the brain's default mode and its anti-correlated network in healthy subjects. Brain Res (2009) 1.60
Commercially available outbred mice for genome-wide association studies. PLoS Genet (2010) 1.58
Number, density, and surface/cytoplasmic distribution of GABA transporters at presynaptic structures of knock-in mice carrying GABA transporter subtype 1-green fluorescent protein fusions. J Neurosci (2002) 1.58
The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis. Neoplasia (2013) 1.58
A systematic review of p53 as a biomarker of survival in patients with osteosarcoma. Tumour Biol (2013) 1.57
Stretchable GaAs photovoltaics with designs that enable high areal coverage. Adv Mater (2011) 1.56
Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family. Plant Cell (2003) 1.56
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Mol Cell Proteomics (2012) 1.55
Evaluation of strong cation exchange versus isoelectric focusing of peptides for multidimensional liquid chromatography-tandem mass spectrometry. J Proteome Res (2008) 1.55
Acoustic environment determines phosphorylation state of the Kv3.1 potassium channel in auditory neurons. Nat Neurosci (2005) 1.55
Th1 and Th17 cells induce proliferative glomerulonephritis. J Am Soc Nephrol (2009) 1.55
Dynamic evolution of oryza genomes is revealed by comparative genomic analysis of a genus-wide vertical data set. Plant Cell (2008) 1.55
Discovering patterns to extract protein-protein interactions from the literature: Part II. Bioinformatics (2005) 1.55
Methodological reporting quality of randomized controlled trials in three spine journals from 2010 to 2012. Eur Spine J (2014) 1.55
ExonHunter: a comprehensive approach to gene finding. Bioinformatics (2005) 1.55
Aberrant subclavian artery pathologies and Kommerell's diverticulum: a review and analysis of published endovascular/hybrid treatment options. J Endovasc Ther (2012) 1.54
Mutation of the rice Narrow leaf1 gene, which encodes a novel protein, affects vein patterning and polar auxin transport. Plant Physiol (2008) 1.54
Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of patient-derived tumor xenograft models. Clin Cancer Res (2012) 1.53
An indole-3-acetic acid carboxyl methyltransferase regulates Arabidopsis leaf development. Plant Cell (2005) 1.53
Rapid formin-mediated actin-filament elongation is essential for polarized plant cell growth. Proc Natl Acad Sci U S A (2009) 1.52
Comparative and phylogenomic studies on the mitochondrial genomes of Pentatomomorpha (Insecta: Hemiptera: Heteroptera). BMC Genomics (2008) 1.52
DJ-1 may contribute to metastasis of non-small cell lung cancer. Mol Biol Rep (2011) 1.52
Highly complex neutralization determinants on a monophyletic lineage of newly transmitted subtype C HIV-1 Env clones from India. Virology (2009) 1.51
Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies. PLoS Comput Biol (2010) 1.51