Published in Proc Natl Acad Sci U S A on July 01, 1986
Metal-specific synthesis of two metallothioneins and gamma-glutamyl peptides in Candida glabrata. Proc Natl Acad Sci U S A (1988) 2.07
Glutathione is required for intestinal function. Proc Natl Acad Sci U S A (1990) 1.43
Isolation, genetic mapping, and characterization of Escherichia coli K-12 mutants lacking gamma-glutamyltranspeptidase. J Bacteriol (1987) 1.30
Prominent role of gamma-glutamyl-transpeptidase on the growth of Helicobacter pylori. World J Gastroenterol (2004) 0.81
A role for gamma-glutamyl transpeptidase and the amino acid transport system xc- in cystine transport by a human pancreatic duct cell line. J Physiol (1995) 0.78
Benzene oxide is a substrate for glutathione S-transferases. Chem Biol Interact (2015) 0.77
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem (1969) 15.62
Glutathione. Annu Rev Biochem (1983) 15.18
Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal Biochem (1980) 10.52
Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol (1985) 7.45
Interaction of gamma-glutamyl transpeptidase with amino acids, dipeptides, and derivatives and analogs of glutathione. J Biol Chem (1974) 3.18
Glutathione: interorgan translocation, turnover, and metabolism. Proc Natl Acad Sci U S A (1979) 2.71
Translocation of intracellular glutathione to membrane-bound gamma-glutamyl transpeptidase as a discrete step in the gamma-glutamyl cycle: glutathionuria after inhibition of transpeptidase. Proc Natl Acad Sci U S A (1979) 2.20
GAMMA-GLUTAMYL-P-NITROANILIDE: A NEW CONVENIENT SUBSTRATE FOR DETERMINATION AND STUDY OF L- AND D-GAMMA-GLUTAMYLTRANSPEPTIDASE ACTIVITIES. Biochim Biophys Acta (1963) 2.12
A COLORIMETRIC MICRO-METHOD FOR THE DETERMINATION OF GLUTATHIONE. Biochem J (1965) 1.90
Glutathione monoethyl ester: preparation, uptake by tissues, and conversion to glutathione. Arch Biochem Biophys (1985) 1.82
gamma-Glutamyl transpeptidase from kidney. Methods Enzymol (1985) 1.69
Gamma-glutamyl transpeptidase. Methods Enzymol (1981) 1.63
Leukotrienes. Annu Rev Biochem (1983) 1.49
Transport and direct utilization of gamma-glutamylcyst(e)ine for glutathione synthesis. Proc Natl Acad Sci U S A (1983) 1.45
Hydrolysis and transfer reactions catalyzed by gamma-glutamyl transpeptidase; evidence for separate substrate sites and for high affinity of L-cystine. Biochem Biophys Res Commun (1976) 1.36
Excretion of cysteine and gamma-glutamylcysteine moieties in human and experimental animal gamma-glutamyl transpeptidase deficiency. Proc Natl Acad Sci U S A (1980) 1.33
Dynamic state of glutathione in blood plasma. J Biol Chem (1980) 1.13
Extracellular metabolism of glutathione accounts for its disappearance from the basolateral circulation of the kidney. J Biol Chem (1984) 1.03
Intrahepatic transport and utilization of biliary glutathione and its metabolites. Proc Natl Acad Sci U S A (1986) 1.02
Preparation of gamma-glutamyl amino acids by chemical and enzymatic methods. Methods Enzymol (1985) 0.98
A new antitumor antimetabolite, (alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (NSC-163501): antimicrobial reversal studies and preliminary evaluation against L1210 mouse leukemia in vivo. Cancer Chemother Rep (1973) 0.95
Formation of gamma-glutamycyst(e)ine in vivo is catalyzed by gamma-glutamyl transpeptidase. Proc Natl Acad Sci U S A (1981) 0.94
Biochemical and pharmacological effects of the fermentation-derived antitumor agent, (alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125). Cancer Res (1979) 0.88
gamma-Glutamyl amino acids. Transport and conversion to 5-oxoproline in the kidney. J Biol Chem (1985) 0.83
Glutathione. Annu Rev Biochem (1983) 15.18
Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol (1985) 7.45
Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J Biol Chem (1979) 7.16
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis. Nat Genet (2001) 6.36
CoREST: a functional corepressor required for regulation of neural-specific gene expression. Proc Natl Acad Sci U S A (1999) 4.59
Regulation of neuronal traits by a novel transcriptional complex. Neuron (2001) 4.02
Glutathione and related gamma-glutamyl compounds: biosynthesis and utilization. Annu Rev Biochem (1976) 3.84
Selective modification of glutathione metabolism. Science (1983) 3.64
On the enzymology of amino acid transport. Science (1973) 3.24
Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione. J Biol Chem (1975) 3.23
High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis. Proc Natl Acad Sci U S A (1992) 3.22
Interaction of gamma-glutamyl transpeptidase with amino acids, dipeptides, and derivatives and analogs of glutathione. J Biol Chem (1974) 3.18
The gamma-glutamyl cycle: a possible transport system for amino acids. Proc Natl Acad Sci U S A (1970) 3.13
Studies on the mechanism of inhibition of glutamine synthetase by methionine sulfoximine. Biochemistry (1969) 3.10
Cytologically integrated physical restriction fragment length polymorphism maps for the barley genome based on translocation breakpoints. Genetics (2000) 3.05
Retracted Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat Cell Biol (2000) 2.86
p53 domains: identification and characterization of two autonomous DNA-binding regions. Genes Dev (1993) 2.74
Glutathione: interorgan translocation, turnover, and metabolism. Proc Natl Acad Sci U S A (1979) 2.71
Pan: a transcriptional regulator that binds chymotrypsin, insulin, and AP-4 enhancer motifs. Genes Dev (1990) 2.46
Origin and turnover of mitochondrial glutathione. Proc Natl Acad Sci U S A (1985) 2.37
Three domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen. J Virol (1990) 2.24
Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens. Proc Natl Acad Sci U S A (1990) 2.22
Translocation of intracellular glutathione to membrane-bound gamma-glutamyl transpeptidase as a discrete step in the gamma-glutamyl cycle: glutathionuria after inhibition of transpeptidase. Proc Natl Acad Sci U S A (1979) 2.20
Catalytic and regulatory properties of the heavy subunit of rat kidney gamma-glutamylcysteine synthetase. J Biol Chem (1993) 2.13
An efficient screen for reproductive pathways using mature seeds of monocots and dicots. Plant J (2000) 2.11
Serine-borate complex as a transition-state inhibitor of gamma-glutamyl transpeptidase. Proc Natl Acad Sci U S A (1978) 2.03
gamma-Glutamyl transpeptidase: catalytic, structural and functional aspects. Mol Cell Biochem (1981) 1.98
Inhibition of glutathione biosynthesis by prothionine sulfoximine (S-n-propyl homocysteine sulfoximine), a selective inhibitor of gamma-glutamylcysteine synthetase. J Biol Chem (1979) 1.91
Role of cysteine residues in regulation of p53 function. Mol Cell Biol (1995) 1.91
The specificity of glutamine synthetase and its relationship to substrate conformation at the active site. Adv Enzymol Relat Areas Mol Biol (1968) 1.91
Enzymatic conversion of 5-oxo-L-proline (L-pyrrolidone carboxylate) to L-glutamate coupled with cleavage of adenosine triphosphate to adenosine diphosphate, a reaction in the -glutamyl cycle. Proc Natl Acad Sci U S A (1971) 1.90
Isolation and properties of gamma-L-glutamylcyclotransferase from human brain. Biochemistry (1969) 1.89
Glutathione monoethyl ester: preparation, uptake by tissues, and conversion to glutathione. Arch Biochem Biophys (1985) 1.82
Identification of L-methionine S-sulfoximine as the diastereoisomer of L-methionine SR-sulfoximine that inhibits glutamine synthetase. Biochemistry (1969) 1.82
Cooperative assembly of simian virus 40 T-antigen hexamers on functional halves of the replication origin. J Virol (1991) 1.78
gamma-Glutamyl transpeptidase, a lymphoid cell-surface marker: relationship to blastogenesis, differentiation, and neoplasia. Proc Natl Acad Sci U S A (1976) 1.78
Glutathione export by human lymphoid cells: depletion of glutathione by inhibition of its synthesis decreases export and increases sensitivity to irradiation. Proc Natl Acad Sci U S A (1981) 1.77
Evidence that the gamma-glutamyl cycle functions in vivo using intracellular glutathione: effects of amino acids and selective inhibition of enzymes. Proc Natl Acad Sci U S A (1978) 1.77
Studies on glutamine synthetase from Escherichia coli. Formation of pyrrolidone carboxylate and inhibition by methionine sulfoximine. J Biol Chem (1973) 1.76
Histone H4 acetylation of euchromatin and heterochromatin is cell cycle dependent and correlated with replication rather than with transcription. Plant Cell (2000) 1.75
Urinary tract infections due to Staphylococcus saprophyticus biotype 3. Can Med Assoc J (1981) 1.75
Phosphorylation of methionine sulfoximine by glutamine synthetase. Proc Natl Acad Sci U S A (1968) 1.72
gamma-Glutamyl transpeptidase from kidney. Methods Enzymol (1985) 1.69
p53 domains: structure, oligomerization, and transformation. Mol Cell Biol (1994) 1.68
Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester. Proc Natl Acad Sci U S A (1989) 1.66
Association of Enzymatic Activity with Submicroscopic Particles. Science (1952) 1.65
Gamma-glutamyl transpeptidase. Methods Enzymol (1981) 1.63
CaM kinase augments cardiac L-type Ca2+ current: a cellular mechanism for long Q-T arrhythmias. Am J Physiol (1999) 1.62
The effects of movement velocity, mass displaced, and task certainty on associated postural adjustments made by normal and hemiplegic individuals. J Neurol Neurosurg Psychiatry (1984) 1.62
Determinants for calmodulin binding on voltage-dependent Ca2+ channels. J Biol Chem (2000) 1.61
Pause-dependent polymorphic ventricular tachycardia during long-term treatment with dofetilide: a placebo-controlled, implantable cardioverter-defibrillator-based evaluation. J Am Coll Cardiol (2001) 1.60
Control of Escherichia coli carbamyl phosphate synthetase by purine and pyrimidine nucleotides. Biochemistry (1966) 1.58
-Glutamyl cyclotransferase. Distribution, isozymic forms, and specificity. J Biol Chem (1973) 1.56
Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system. Circ Res (1999) 1.55
The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation. Proc Natl Acad Sci U S A (1995) 1.52
Amino acid sequence and function of the light subunit of rat kidney gamma-glutamylcysteine synthetase. J Biol Chem (1993) 1.52
Interconversion of leukotrienes catalyzed by purified gamma-glutamyl transpeptidase: concomitant formation of leukotriene D4 and gamma-glutamyl amino acids. Proc Natl Acad Sci U S A (1982) 1.52
Glutathione synthetase deficiency, an inborn error of metabolism involving the gamma-glutamyl cycle in patients with 5-oxoprolinuria (pyroglutamic aciduria). Proc Natl Acad Sci U S A (1974) 1.51
Identity of maleate-stimulated glutaminase with gamma-glutamyl transpeptidase in rat kidney. J Biol Chem (1975) 1.50
Glutathione biosynthesis; gamma-glutamylcysteine synthetase from rat kidney. Methods Enzymol (1985) 1.50
Speckle tracking for multi-dimensional flow estimation. Ultrasonics (2000) 1.50
Asparagine synthetase activity of mouse leukemias. Science (1968) 1.49
Critical spatial requirement within the origin of simian virus 40 DNA replication. J Virol (1984) 1.49
Tripeptide (glutathione) synthetase. Purification, properties, and mechanism of action. Biochemistry (1967) 1.46
Affinity labeling of gamma-glutamyl transpeptidase and location of the gamma-glutamyl binding site on the light subunit. Proc Natl Acad Sci U S A (1977) 1.45
Should fewer premature infants be screened for retinopathy of prematurity in the managed care era? Pediatrics (1998) 1.45
Transport and direct utilization of gamma-glutamylcyst(e)ine for glutathione synthesis. Proc Natl Acad Sci U S A (1983) 1.45
Glutamine-dependent asparagine synthetase from leukemia cells. Chloride dependence, mechanism of action, and inhibition. J Biol Chem (1972) 1.45
Glutathione, a first line of defense against cadmium toxicity. FASEB J (1987) 1.44
Reversible dissociation of gamma-glutamylcysteine synthetase into two subunits. J Biol Chem (1984) 1.44
Glutathione deficiency leads to mitochondrial damage in brain. Proc Natl Acad Sci U S A (1991) 1.43
Enzymes of the gamma-glutamyl cycle in the ciliary body and lens. Proc Natl Acad Sci U S A (1973) 1.43
Glutathione is required for intestinal function. Proc Natl Acad Sci U S A (1990) 1.43
Inhibition of glutathione synthesis in the newborn rat: a model for endogenously produced oxidative stress. Proc Natl Acad Sci U S A (1991) 1.43
The gamma-glutamyl cycle. Diseases associated with specific enzyme deficiencies. Ann Intern Med (1974) 1.43
Translocation of glutathione from lymphoid cells that have markedly different gamma-glutamyl transpeptidase activities. Proc Natl Acad Sci U S A (1979) 1.43
Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine. Proc Natl Acad Sci U S A (1991) 1.40
Resolution of the light-harvesting chlorophyll a/b-protein of vicia faba chloroplasts into two different chlorophyll-protein complexes. Biochim Biophys Acta (1979) 1.38
Transport of gamma-glutamyl amino acids: role of glutathione and gamma-glutamyl transpeptidase. Proc Natl Acad Sci U S A (1979) 1.38
Accumulation of 5-oxoproline in mouse tissues after inhibition of 5-oxoprolinase and administration of amino acids: evidence for function of the gamma-glutamyl cycle. Proc Natl Acad Sci U S A (1974) 1.37
Glutathione ester prevents buthionine sulfoximine-induced cataracts and lens epithelial cell damage. Proc Natl Acad Sci U S A (1989) 1.37
Stimulation of the hydrolytic activity and decrease of the transpeptidase activity of gamma-glutamyl transpeptidase by maleate; identity of a rat kidney maleate-stimulated glutaminase and gamma-glutamyl transpeptidase. Proc Natl Acad Sci U S A (1974) 1.37
Regulation of rat liver glutamine synthetase: activation by alpha-ketoglutarate and inhibition by glycine, alanine, and carbamyl phosphate. Proc Natl Acad Sci U S A (1971) 1.37
Hydrolysis and transfer reactions catalyzed by gamma-glutamyl transpeptidase; evidence for separate substrate sites and for high affinity of L-cystine. Biochem Biophys Res Commun (1976) 1.36
Rat liver glutamine synthetase. Preparation, properties, and mechanism of inhibition by carbamyl phosphate. J Biol Chem (1972) 1.36
Glutamine-binding subunit of glutamate synthase and partial reactions catalyzed by this glutamine amidotransferase. Proc Natl Acad Sci U S A (1974) 1.36
Inhibition of 5-oxoprolinase by 2-imidazolidone-4-carboxylic acid. Proc Natl Acad Sci U S A (1973) 1.36
Reversible dissociation of carbamyl phosphate synthetase into a regulated synthesis subunit and a subunit required for glutamine utilization. Proc Natl Acad Sci U S A (1971) 1.35
Radioprotection by glutathione ester: transport of glutathione ester into human lymphoid cells and fibroblasts. Proc Natl Acad Sci U S A (1984) 1.35