Published in Blood on January 01, 1989
Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo. Proc Natl Acad Sci U S A (2003) 1.88
Development and characterization of novel erythropoiesis stimulating protein (NESP). Br J Cancer (2001) 1.72
Role of erythropoietin in the brain. Crit Rev Oncol Hematol (2007) 1.50
Survival and proliferative roles of erythropoietin beyond the erythroid lineage. Expert Rev Mol Med (2008) 1.36
Developments in the identification of glycan biomarkers for the detection of cancer. Mol Cell Proteomics (2013) 1.12
Glycotherapy: new advances inspire a reemergence of glycans in medicine. Chem Biol (2013) 1.04
Glycosylation of human milk lactoferrin exhibits dynamic changes during early lactation enhancing its role in pathogenic bacteria-host interactions. Mol Cell Proteomics (2012) 1.02
The pharmacokinetics and pharmacodynamics of recombinant human erythropoietin in haemodialysis patients. Br J Clin Pharmacol (1992) 1.01
Safety of epoietin beta-quinine drug combination in children with cerebral malaria in Mali. Malar J (2009) 1.01
Enzymatic basis for N-glycan sialylation: structure of rat α2,6-sialyltransferase (ST6GAL1) reveals conserved and unique features for glycan sialylation. J Biol Chem (2013) 1.01
Engineering of sialylated mucin-type O-glycosylation in plants. J Biol Chem (2012) 0.99
Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin. Angew Chem Int Ed Engl (2011) 0.93
Enhancement of ventricular-subventricular zone-derived neurogenesis and oligodendrogenesis by erythropoietin and its derivatives. Front Cell Neurosci (2013) 0.91
Engineered CHO cells for production of diverse, homogeneous glycoproteins. Nat Biotechnol (2015) 0.91
The GalNAc-type O-Glycoproteome of CHO cells characterized by the SimpleCell strategy. Mol Cell Proteomics (2014) 0.89
Erythropoietin in brain development and beyond. Anat Res Int (2012) 0.86
Analysis of glycans derived from glycoconjugates by capillary electrophoresis-mass spectrometry. Electrophoresis (2011) 0.86
2D-LC analysis of BRP 3 erythropoietin N-glycosylation using anion exchange fractionation and hydrophilic interaction UPLC reveals long poly-N-acetyl lactosamine extensions. Anal Chem (2011) 0.85
A safety evaluation of DAS181, a sialidase fusion protein, in rodents. Toxicol Sci (2011) 0.85
N-Glycosylation engineering of tobacco plants to produce asialoerythropoietin. Plant Cell Rep (2012) 0.84
Natural form of noncytolytic flexible human Fc as a long-acting carrier of agonistic ligand, erythropoietin. PLoS One (2011) 0.84
Design of homogeneous, monopegylated erythropoietin analogs with preserved in vitro bioactivity. Exp Hematol (2006) 0.84
Change in erythropoietin pharmacokinetics following hematopoietic transplantation. Clin Pharmacol Ther (2007) 0.83
Targeted biomarker discovery by high throughput glycosylation profiling of human plasma alpha1-antitrypsin and immunoglobulin A. PLoS One (2013) 0.82
Comparative study of idursulfase beta and idursulfase in vitro and in vivo. J Hum Genet (2016) 0.81
Erythropoiesis suppression is associated with anthrax lethal toxin-mediated pathogenic progression. PLoS One (2013) 0.80
Green algae Chlamydomonas reinhardtii possess endogenous sialylated N-glycans. FEBS Open Bio (2011) 0.80
Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care. Crit Care (2012) 0.80
Erythropoiesis stimulating agents: approaches to modulate activity. Biologics (2013) 0.80
Methods development for Analysis of Partially Deglycosylated Proteins and Application to an HIV Envelope Protein Vaccine Candidate. Int J Mass Spectrom (2011) 0.80
Engineering β1,4-galactosyltransferase I to reduce secretion and enhance N-glycan elongation in insect cells. J Biotechnol (2014) 0.79
Novel recombinant human lactoferrin: differential activation of oxidative stress related gene expression. J Biotechnol (2013) 0.79
N-glycosylation modification of plant-derived virus-like particles: an application in vaccines. Biomed Res Int (2014) 0.79
Improvement of in vivo efficacy of recombinant human erythropoietin by encapsulation in PEG-PLA micelle. Int J Nanomedicine (2012) 0.78
Overloading and removal of N-glycosylation targets on human acetylcholinesterase: effects on glycan composition and circulatory residence time. Biochem J (2002) 0.78
Rapid assays for lectin toxicity and binding changes that reflect altered glycosylation in mammalian cells. Curr Protoc Chem Biol (2014) 0.77
Receptor-based dosing optimization of erythropoietin in juvenile sheep after phlebotomy. Drug Metab Dispos (2011) 0.77
Erythropoietin use and abuse. Indian J Endocrinol Metab (2012) 0.77
Integration of systems glycobiology with bioinformatics toolboxes, glycoinformatics resources, and glycoproteomics data. Wiley Interdiscip Rev Syst Biol Med (2015) 0.77
The influence of artificially introduced N-glycosylation sites on the in vitro activity of Xenopus laevis erythropoietin. PLoS One (2015) 0.77
Quantitation of human milk proteins and their glycoforms using multiple reaction monitoring (MRM). Anal Bioanal Chem (2016) 0.77
Plant-produced human recombinant erythropoietic growth factors support erythroid differentiation in vitro. Stem Cells Dev (2013) 0.76
An Integrated Approach for a Structural and Functional Evaluation of Biosimilars: Implications for Erythropoietin. BioDrugs (2015) 0.76
Characterization of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori). MAbs (2015) 0.76
Applications of Multiple Reaction Monitoring to Clinical Glycomics. Chromatographia (2015) 0.76
Fucosylated Glycans in α1-Acid Glycoprotein for Monitoring Treatment Outcomes and Prognosis of Cancer Patients. PLoS One (2016) 0.75
Producing recombinant therapeutic glycoproteins with enhanced sialylation using CHO-gmt4 glycosylation mutant cells. Bioengineered (2014) 0.75
Enhancement of recombinant erythropoietin production in CHO cells in an incubator without CO(2) addition. Cytotechnology (2001) 0.75
The Diversity of Biosimilar Design and Development: Implications for Policies and Stakeholders. BioDrugs (2015) 0.75
Neuroprotective activity of a new erythropoietin formulation with increased penetration in the central nervous system. BMC Proc (2011) 0.75
A rationally engineered yeast pyruvyltransferase Pvg1p introduces sialylation-like properties in neo-human-type complex oligosaccharide. Sci Rep (2016) 0.75
Structural Identification of a Non-Glycosylated Variant at Ser126 for O-Glycosylation Site from EPO BRP, Human Recombinant Erythropoietin by LC/MS Analysis. Mol Cells (2015) 0.75
Enhancing the sialylation of recombinant EPO produced in CHO cells via the inhibition of glycosphingolipid biosynthesis. Sci Rep (2017) 0.75
Functional annotation of a full-length mouse cDNA collection. Nature (2001) 23.61
Ecological meltdown in predator-free forest fragments. Science (2001) 9.84
Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300. EMBO J (1998) 6.94
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science (1995) 6.37
The Cognitive Abilities Screening Instrument (CASI): a practical test for cross-cultural epidemiological studies of dementia. Int Psychogeriatr (1994) 5.47
Acquired growth hormone deficiency due to pituitary stalk transection after head trauma in childhood. Eur J Pediatr (1993) 5.16
Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell (2000) 4.69
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol (1998) 4.64
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation. J Biol Chem (2001) 4.51
Pandemic influenza A(H1N1)v in New Zealand: the experience from April to August 2009. Euro Surveill (2009) 4.23
Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Mol Psychiatry (2011) 4.16
Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. J Exp Med (1991) 4.15
Cloning and sequencing of two tandem genes involved in degradation of 2,3-dihydroxybiphenyl to benzoic acid in the polychlorinated biphenyl-degrading soil bacterium Pseudomonas sp. strain KKS102. J Bacteriol (1989) 3.83
Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J Cell Biol (1999) 3.78
Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells. J Cell Biol (2001) 3.66
Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol (1999) 3.57
Relationship between antimycobacterial activities of rifampicin, rifabutin and KRM-1648 and rpoB mutations of Mycobacterium tuberculosis. J Antimicrob Chemother (1998) 3.41
Magnifying endoscopy combined with narrow band imaging system for early gastric cancer: correlation of vascular pattern with histopathology (including video). Endoscopy (2004) 3.36
Regulation of imprinted X-chromosome inactivation in mice by Tsix. Development (2001) 3.12
Parental-origin-specific epigenetic modification of the mouse H19 gene. Nature (1993) 3.11
Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT. Nat Genet (1996) 3.07
Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia. Blood (2001) 3.07
Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am J Hum Genet (2000) 3.06
Distribution of bifidobacterial species in human intestinal microflora examined with 16S rRNA-gene-targeted species-specific primers. Appl Environ Microbiol (1999) 3.06
Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan. J Biol Chem (1988) 3.05
Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier. J Cell Biol (1999) 3.02
Basal cell carcinomas in mice overexpressing Gli2 in skin. Nat Genet (2000) 2.82
Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell (1995) 2.81
Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M. Nat Genet (1996) 2.77
Amantadine and pneumonia. Lancet (1999) 2.69
Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development (1998) 2.67
Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail. J Cell Biol (1990) 2.57
Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2. Proc Natl Acad Sci U S A (1997) 2.52
Characterization of biphenyl catabolic genes of gram-positive polychlorinated biphenyl degrader Rhodococcus sp. strain RHA1. Appl Environ Microbiol (1995) 2.47
Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. Nature (1993) 2.45
Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis. J Cell Biol (1999) 2.40
Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testis. J Cell Biol (1999) 2.40
ACE inhibitors and pneumonia. Lancet (1998) 2.38
Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint. EMBO J (1998) 2.38
Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases. Nucleic Acids Res (2001) 2.36
Treatment of hemoptysis patients by thrombin and fibrinogen-thrombin infusion therapy using a fiberoptic bronchoscope. Chest (1989) 2.36
Pro----leu change at position 102 of prion protein is the most common but not the sole mutation related to Gerstmann-Sträussler syndrome. Biochem Biophys Res Commun (1989) 2.35
A Novel Transformation of Polychlorinated Biphenyls by Rhodococcus sp. Strain RHA1. Appl Environ Microbiol (1995) 2.35
Motoneuron-disease-like disorder after ganglioside therapy. Lancet (1991) 2.30
Molecular subtypes of anaplastic oligodendroglioma: implications for patient management at diagnosis. Clin Cancer Res (2001) 2.28
A simple method for estimating 24 h urinary sodium and potassium excretion from second morning voiding urine specimen in adults. Clin Exp Pharmacol Physiol (1993) 2.26
Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan. Ann Neurol (1998) 2.25
Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase. Proc Natl Acad Sci U S A (1994) 2.25
Association of Trp64Arg mutation of the beta3-adrenergic-receptor with NIDDM and body weight gain. Diabetologia (1996) 2.22
Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients. J Hepatol (1998) 2.21
MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis. J Neurochem (2003) 2.21
Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice. Proc Natl Acad Sci U S A (2000) 2.19
Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines. Biochem Biophys Res Commun (2000) 2.14
Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis. Cancer Res (1994) 2.13
Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack. Chest (1992) 2.13
Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr Biol (1999) 2.12
Rapid detection of chromosome aneuploidies in uncultured amniocytes by using fluorescence in situ hybridization (FISH). Am J Hum Genet (1992) 2.09
Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions. J Cell Biol (2001) 2.06
Molecular cloning of a Pseudomonas paucimobilis gene encoding a 17-kilodalton polypeptide that eliminates HCl molecules from gamma-hexachlorocyclohexane. J Bacteriol (1991) 2.03
Site of airway obstruction in pulmonary disease: direct measurement of intrabronchial pressure. J Appl Physiol (1985) (1992) 2.01
Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation. Immunity (1998) 2.00
Three-dimensional structures of free form and two substrate complexes of an extradiol ring-cleavage type dioxygenase, the BphC enzyme from Pseudomonas sp. strain KKS102. J Mol Biol (1996) 1.98
FGF-2 stimulates periodontal regeneration: results of a multi-center randomized clinical trial. J Dent Res (2010) 1.92
Novel sulfated lymphocyte homing receptors and their control by a Core1 extension beta 1,3-N-acetylglucosaminyltransferase. Cell (2001) 1.90
Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer. EMBO J (1999) 1.90
Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein. EMBO J (1998) 1.89
Tomographic 3D reconstruction of quick-frozen, Ca2+-activated contracting insect flight muscle. Cell (1999) 1.85
Bisulfite sequencing and dinucleotide content analysis of 15 imprinted mouse differentially methylated regions (DMRs): paternally methylated DMRs contain less CpGs than maternally methylated DMRs. Cytogenet Genome Res (2006) 1.84
The ST3Gal-I sialyltransferase controls CD8+ T lymphocyte homeostasis by modulating O-glycan biosynthesis. Immunity (2000) 1.83
The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm. Development (2001) 1.83
Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss. J Neurosurg (2000) 1.82
Fecal excretion of a nonenveloped DNA virus (TTV) associated with posttransfusion non-A-G hepatitis. J Med Virol (1998) 1.82
Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen. Proc Natl Acad Sci U S A (1992) 1.79
Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions. Curr Biol (1999) 1.78
Erythromycin and common cold in COPD. Chest (2001) 1.78
Development of spectral colour banding in cytogenetic analysis. Lancet (2001) 1.78
Risk factors of aspiration pneumonia in Alzheimer's disease patients. Gerontology (2001) 1.77
Carbohydrate structure of erythropoietin expressed in Chinese hamster ovary cells by a human erythropoietin cDNA. J Biol Chem (1987) 1.76
The clinical and genetic spectrum of spinocerebellar ataxia 14. Neurology (2005) 1.74
Characterization of cry genes in a Mexican Bacillus thuringiensis strain collection. Appl Environ Microbiol (1998) 1.74
Isolation and characterization of leukosialin, a major sialoglycoprotein on human leukocytes. J Biol Chem (1986) 1.74
Identification of the bphA4 gene encoding ferredoxin reductase involved in biphenyl and polychlorinated biphenyl degradation in Pseudomonas sp. strain KKS102. J Bacteriol (1994) 1.74
ACE inhibitor and swallowing reflex. Chest (1998) 1.73
Glucagon: role in the hyperglycemia of diabetes mellitus. Science (1975) 1.72
Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the Ftz-F1 disrupted mice. Dev Dyn (1995) 1.72
Electron microscopic studies of Dane particles in hepatocytes with special reference to intracellular development of Dane particles and their relation with HBeAg in serum. Hepatology (1982) 1.72
Differential glycosylation and cell surface expression of lysosomal membrane glycoproteins in sublines of a human colon cancer exhibiting distinct metastatic potentials. J Biol Chem (1992) 1.71
Characterization of cDNAs encoding human leukosialin and localization of the leukosialin gene to chromosome 16. Proc Natl Acad Sci U S A (1989) 1.68
Cloning and sequencing of a dehalogenase gene encoding an enzyme with hydrolase activity involved in the degradation of gamma-hexachlorocyclohexane in Pseudomonas paucimobilis. J Bacteriol (1993) 1.67
A cDNA clone used to study mRNA inducible in human tonsillar lymphocytes by a tumor promoter. J Biochem (1986) 1.66
Structure of sialylated fucosyl lactosaminoglycan isolated from human granulocytes. J Biol Chem (1984) 1.65
Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells. Diabetologia (2008) 1.64
GNE mutations causing distal myopathy with rimmed vacuoles with inflammation. Neurology (2003) 1.63
Human T-lymphocyte activation is associated with changes in O-glycan biosynthesis. J Biol Chem (1988) 1.63
Relationship between C-reactive protein and visceral adipose tissue in healthy Japanese subjects. Diabetes Obes Metab (2004) 1.62
A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells. J Neurochem (1994) 1.62
Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism. J Cell Biol (2000) 1.60
Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration. J Biol Chem (1999) 1.60